Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005148                                                              20     390
NP_009297                                                              20     390
NP_055553                                                              17    4312
XP_005257925                                                           17    4312
XP_005257924                                                           17    4312
XP_005257923                                                           17    4312
XP_005257922                                                           17    4312
XP_005257921                                                           17    4312
XP_006722263                                                           17    4312
XP_005257920                                                           17    4312
NP_000193                                                              16    7355
NP_006114                                                              16    7355
NP_000126                                                              15    9605
NP_001018122                                                           15    9605
NP_001010872                                                           15    9605
NP_001138473                                                           15    9605
NP_001273096                                                           15    9605
NP_001159643                                                           15    9605
NP_001159639                                                           15    9605
NP_001002836                                                           15    9605
NP_001159641                                                           15    9605
NP_001159640                                                           15    9605
NP_001159642                                                           15    9605
NP_055212                                                              15    9605
XP_005256351                                                           15    9605
XP_006721230                                                           15    9605
XP_006716999                                                           15    9605
XP_005251721                                                           15    9605
XP_006716998                                                           15    9605
XP_006716997                                                           15    9605
XP_005277661                                                           15    9605
XP_006715085                                                           15    9605
>NP_005148
          Length = 1130

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SSEQMASHS 9
            +SEQMASHS
Sbjct: 1046 NSEQMASHS 1054
>NP_009297
          Length = 1149

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SSEQMASHS 9
            +SEQMASHS
Sbjct: 1065 NSEQMASHS 1073
>NP_055553
          Length = 1356

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSEQMASH 8
           S+EQM SH
Sbjct: 696 STEQMLSH 703
>XP_005257925
          Length = 850

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSEQMASH 8
           S+EQM SH
Sbjct: 160 STEQMLSH 167
>XP_005257924
          Length = 1122

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSEQMASH 8
           S+EQM SH
Sbjct: 432 STEQMLSH 439
>XP_005257923
          Length = 1131

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSEQMASH 8
           S+EQM SH
Sbjct: 441 STEQMLSH 448
>XP_005257922
          Length = 1366

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSEQMASH 8
           S+EQM SH
Sbjct: 706 STEQMLSH 713
>XP_005257921
          Length = 1370

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSEQMASH 8
           S+EQM SH
Sbjct: 710 STEQMLSH 717
>XP_006722263
          Length = 1390

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSEQMASH 8
           S+EQM SH
Sbjct: 700 STEQMLSH 707
>XP_005257920
          Length = 1390

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SSEQMASH 8
           S+EQM SH
Sbjct: 700 STEQMLSH 707
>NP_000193
          Length = 550

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  EQMASHS 9
          +Q+ASHS
Sbjct: 65 DQLASHS 71
>NP_006114
          Length = 343

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  EQMASHS 9
          +Q+ASHS
Sbjct: 65 DQLASHS 71
>NP_000126
          Length = 1455

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  SSEQMASHS 9
          SSE  A+HS
Sbjct: 82 SSEAYANHS 90
>NP_001018122
          Length = 297

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  SSEQMASHS 9
          SSE  A+HS
Sbjct: 82 SSEAYANHS 90
>NP_001010872
          Length = 1011

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SSEQMASHS 9
           SSE + SHS
Sbjct: 920 SSELLRSHS 928
>NP_001138473
          Length = 347

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SSEQMASHS 9
           SSE  A+HS
Sbjct: 232 SSETTAAHS 240
>NP_001273096
          Length = 1424

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  SSEQMASHS 9
          SSE  A+HS
Sbjct: 82 SSEAYANHS 90
>NP_001159643
          Length = 347

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SSEQMASHS 9
           SSE  A+HS
Sbjct: 232 SSETTAAHS 240
>NP_001159639
          Length = 331

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SSEQMASHS 9
           SSE  A+HS
Sbjct: 216 SSETTAAHS 224
>NP_001002836
          Length = 382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  EQMASH 8
          +QMASH
Sbjct: 18 QQMASH 23
>NP_001159641
          Length = 338

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SSEQMASHS 9
           SSE  A+HS
Sbjct: 223 SSETTAAHS 231
>NP_001159640
          Length = 313

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SSEQMASHS 9
           SSE  A+HS
Sbjct: 198 SSETTAAHS 206
>NP_001159642
          Length = 313

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SSEQMASHS 9
           SSE  A+HS
Sbjct: 198 SSETTAAHS 206
>NP_055212
          Length = 313

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SSEQMASHS 9
           SSE  A+HS
Sbjct: 198 SSETTAAHS 206
>XP_005256351
          Length = 1463

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  SSEQMASHS 9
          SSE  A+HS
Sbjct: 82 SSEAYANHS 90
>XP_006721230
          Length = 1412

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  SSEQMASHS 9
          SSE  A+HS
Sbjct: 82 SSEAYANHS 90
>XP_006716999
          Length = 313

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SSEQMASHS 9
           SSE  A+HS
Sbjct: 198 SSETTAAHS 206
>XP_005251721
          Length = 313

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SSEQMASHS 9
           SSE  A+HS
Sbjct: 198 SSETTAAHS 206
>XP_006716998
          Length = 357

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SSEQMASHS 9
           SSE  A+HS
Sbjct: 242 SSETTAAHS 250
>XP_006716997
          Length = 371

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SSEQMASHS 9
           SSE  A+HS
Sbjct: 256 SSETTAAHS 264
>XP_005277661
          Length = 381

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SSEQMASHS 9
           SSE  A+HS
Sbjct: 337 SSEPCATHS 345
>XP_006715085
          Length = 1011

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SSEQMASHS 9
           SSE + SHS
Sbjct: 920 SSELLRSHS 928
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.278   0.0834    0.184 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 470,451
Number of extensions: 653
Number of successful extensions: 32
Number of sequences better than 10000.0: 32
Number of HSP's gapped: 32
Number of HSP's successfully gapped: 32
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.8 bits)
S2: 28 (15.4 bits)

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