Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000537                                                              20     509
NP_001263689                                                           20     509
NP_001119584                                                           20     509
NP_001119586                                                           20     509
NP_001263625                                                           20     509
NP_001119590                                                           20     509
NP_001263690                                                           20     509
NP_001119585                                                           20     509
NP_001263624                                                           20     509
NP_001119588                                                           20     509
NP_001119587                                                           20     509
NP_001119589                                                           20     509
NP_001263627                                                           20     509
NP_001263628                                                           20     509
NP_001263626                                                           20     509
NP_002903                                                              17    4312
NP_001273361                                                           17    4312
NP_001273360                                                           17    4312
XP_005267148                                                           17    4312
XP_005267147                                                           17    4312
XP_006715607                                                           17    4312
XP_006715606                                                           17    4312
NP_055178                                                              16    5631
NP_001264984                                                           16    5631
NP_001123572                                                           16    5631
NP_001123571                                                           16    5631
NP_005541                                                              16    5631
XP_006721253                                                           16    5631
XP_005256003                                                           16    5631
XP_005256002                                                           16    5631
XP_005256001                                                           16    5631
XP_006721252                                                           16    5631
XP_005256000                                                           16    5631
XP_005255994                                                           16    5631
XP_006721251                                                           16    5631
XP_005266395                                                           16    5631
NP_001265617                                                           16    7355
XP_006717747                                                           16    7355
NP_001121782                                                           15    9605
NP_004675                                                              15    9605
NP_001269629                                                           15    9605
NP_006834                                                              15    9605
NP_001269632                                                           15    9605
NP_001269631                                                           15    9605
NP_001269630                                                           15    9605
NP_001269628                                                           15    9605
NP_001269627                                                           15    9605
NP_001269626                                                           15    9605
NP_001269624                                                           15    9605
NP_113641                                                              15    9605
NP_001001521                                                           15    9605
NP_006750                                                              15    9605
NP_002230                                                              15    9605
NP_001269625                                                           15    9605
XP_005252673                                                           15    9605
XP_006712152                                                           15    9605
XP_006712151                                                           15    9605
XP_005264594                                                           15    9605
XP_005264595                                                           15    9605
NP_001073870                                                           15    9605
>NP_000537
          Length = 393

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   RVEGNLRV 9
           RVEGNLRV
Sbjct: 196 RVEGNLRV 203
>NP_001263689
          Length = 354

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   RVEGNLRV 9
           RVEGNLRV
Sbjct: 157 RVEGNLRV 164
>NP_001119584
          Length = 393

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   RVEGNLRV 9
           RVEGNLRV
Sbjct: 196 RVEGNLRV 203
>NP_001119586
          Length = 341

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   RVEGNLRV 9
           RVEGNLRV
Sbjct: 196 RVEGNLRV 203
>NP_001263625
          Length = 302

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   RVEGNLRV 9
           RVEGNLRV
Sbjct: 157 RVEGNLRV 164
>NP_001119590
          Length = 354

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   RVEGNLRV 9
           RVEGNLRV
Sbjct: 157 RVEGNLRV 164
>NP_001263690
          Length = 354

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   RVEGNLRV 9
           RVEGNLRV
Sbjct: 157 RVEGNLRV 164
>NP_001119585
          Length = 346

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   RVEGNLRV 9
           RVEGNLRV
Sbjct: 196 RVEGNLRV 203
>NP_001263624
          Length = 307

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   RVEGNLRV 9
           RVEGNLRV
Sbjct: 157 RVEGNLRV 164
>NP_001119588
          Length = 209

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  RVEGNLRV 9
          RVEGNLRV
Sbjct: 64 RVEGNLRV 71
>NP_001119587
          Length = 261

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  RVEGNLRV 9
          RVEGNLRV
Sbjct: 64 RVEGNLRV 71
>NP_001119589
          Length = 214

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  RVEGNLRV 9
          RVEGNLRV
Sbjct: 64 RVEGNLRV 71
>NP_001263627
          Length = 182

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  RVEGNLRV 9
          RVEGNLRV
Sbjct: 37 RVEGNLRV 44
>NP_001263628
          Length = 187

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  RVEGNLRV 9
          RVEGNLRV
Sbjct: 37 RVEGNLRV 44
>NP_001263626
          Length = 234

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  RVEGNLRV 9
          RVEGNLRV
Sbjct: 37 RVEGNLRV 44
>NP_002903
          Length = 3130

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SRVEGNLRV 9
            SRV GNL++
Sbjct: 2522 SRVRGNLQM 2530
>NP_001273361
          Length = 3052

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SRVEGNLRV 9
            SRV GNL++
Sbjct: 2444 SRVRGNLQM 2452
>NP_001273360
          Length = 3052

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SRVEGNLRV 9
            SRV GNL++
Sbjct: 2444 SRVRGNLQM 2452
>XP_005267148
          Length = 2679

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SRVEGNLRV 9
            SRV GNL++
Sbjct: 2522 SRVRGNLQM 2530
>XP_005267147
          Length = 2689

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SRVEGNLRV 9
            SRV GNL++
Sbjct: 2522 SRVRGNLQM 2530
>XP_006715607
          Length = 3052

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SRVEGNLRV 9
            SRV GNL++
Sbjct: 2444 SRVRGNLQM 2452
>XP_006715606
          Length = 3130

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SRVEGNLRV 9
            SRV GNL++
Sbjct: 2522 SRVRGNLQM 2530
>NP_055178
          Length = 4579

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SRVEGNLRV 9
            SR++GN+ V
Sbjct: 3932 SRIQGNIGV 3940
>NP_001264984
          Length = 4432

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SRVEGNLRV 9
            SR++GN+ V
Sbjct: 3785 SRIQGNIGV 3793
>NP_001123572
          Length = 826

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RVEGNLRV 9
           R++GN+RV
Sbjct: 441 RLKGNIRV 448
>NP_001123571
          Length = 687

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RVEGNLRV 9
           R++GN+RV
Sbjct: 302 RLKGNIRV 309
>NP_005541
          Length = 833

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RVEGNLRV 9
           R++GN+RV
Sbjct: 441 RLKGNIRV 448
>XP_006721253
          Length = 828

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RVEGNLRV 9
           R++GN+RV
Sbjct: 436 RLKGNIRV 443
>XP_005256003
          Length = 768

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RVEGNLRV 9
           R++GN+RV
Sbjct: 383 RLKGNIRV 390
>XP_005256002
          Length = 769

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RVEGNLRV 9
           R++GN+RV
Sbjct: 384 RLKGNIRV 391
>XP_005256001
          Length = 775

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RVEGNLRV 9
           R++GN+RV
Sbjct: 383 RLKGNIRV 390
>XP_006721252
          Length = 775

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RVEGNLRV 9
           R++GN+RV
Sbjct: 383 RLKGNIRV 390
>XP_005256000
          Length = 776

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RVEGNLRV 9
           R++GN+RV
Sbjct: 384 RLKGNIRV 391
>XP_005255994
          Length = 996

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RVEGNLRV 9
           R++GN+RV
Sbjct: 604 RLKGNIRV 611
>XP_006721251
          Length = 1022

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RVEGNLRV 9
           R++GN+RV
Sbjct: 630 RLKGNIRV 637
>XP_005266395
          Length = 4588

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SRVEGNLRV 9
            SR++GN+ V
Sbjct: 3941 SRIQGNIGV 3949
>NP_001265617
          Length = 631

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   RVEGNL 7
           R+EGNL
Sbjct: 441 RIEGNL 446
>XP_006717747
          Length = 601

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   RVEGNL 7
           R+EGNL
Sbjct: 411 RIEGNL 416
>NP_001121782
          Length = 664

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   EGNLRV 9
           EGN+RV
Sbjct: 422 EGNMRV 427
>NP_004675
          Length = 664

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   EGNLRV 9
           EGN+RV
Sbjct: 422 EGNMRV 427
>NP_001269629
          Length = 131

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   RVEGNLR 8
           +V+GNLR
Sbjct: 113 KVKGNLR 119
>NP_006834
          Length = 328

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   RVEGNLR 8
           ++EGNLR
Sbjct: 286 QLEGNLR 292
>NP_001269632
          Length = 131

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   RVEGNLR 8
           +V+GNLR
Sbjct: 113 KVKGNLR 119
>NP_001269631
          Length = 131

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   RVEGNLR 8
           +V+GNLR
Sbjct: 113 KVKGNLR 119
>NP_001269630
          Length = 131

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   RVEGNLR 8
           +V+GNLR
Sbjct: 113 KVKGNLR 119
>NP_001269628
          Length = 131

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   RVEGNLR 8
           +V+GNLR
Sbjct: 113 KVKGNLR 119
>NP_001269627
          Length = 131

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   RVEGNLR 8
           +V+GNLR
Sbjct: 113 KVKGNLR 119
>NP_001269626
          Length = 131

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   RVEGNLR 8
           +V+GNLR
Sbjct: 113 KVKGNLR 119
>NP_001269624
          Length = 131

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   RVEGNLR 8
           +V+GNLR
Sbjct: 113 KVKGNLR 119
>NP_113641
          Length = 306

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   RVEGNLR 8
           +V+GNLR
Sbjct: 288 KVKGNLR 294
>NP_001001521
          Length = 497

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   VEGNLRV 9
           V GNLR+
Sbjct: 488 VSGNLRI 494
>NP_006750
          Length = 508

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   VEGNLRV 9
           V GNLR+
Sbjct: 499 VSGNLRI 505
>NP_002230
          Length = 501

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SRVEGNL 7
           +R+EGNL
Sbjct: 482 ARMEGNL 488
>NP_001269625
          Length = 131

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   RVEGNLR 8
           +V+GNLR
Sbjct: 113 KVKGNLR 119
>XP_005252673
          Length = 131

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   RVEGNLR 8
           +V+GNLR
Sbjct: 113 KVKGNLR 119
>XP_006712152
          Length = 388

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   VEGNLRV 9
           V GNLR+
Sbjct: 379 VSGNLRI 385
>XP_006712151
          Length = 388

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   VEGNLRV 9
           V GNLR+
Sbjct: 379 VSGNLRI 385
>XP_005264594
          Length = 497

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   VEGNLRV 9
           V GNLR+
Sbjct: 488 VSGNLRI 494
>XP_005264595
          Length = 497

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   VEGNLRV 9
           V GNLR+
Sbjct: 488 VSGNLRI 494
>NP_001073870
          Length = 430

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RVEGNLRV 9
           RVEG+L V
Sbjct: 222 RVEGSLAV 229
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.316    0.135    0.349 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 540,363
Number of extensions: 814
Number of successful extensions: 60
Number of sequences better than 10000.0: 60
Number of HSP's gapped: 60
Number of HSP's successfully gapped: 60
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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