Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

XP_006725230                                                           17    4312
XP_006720283                                                           17    4312
NP_001193949                                                           16    7355
XP_006724319                                                           16    7355
XP_006724318                                                           16    7355
XP_006724317                                                           16    7355
NP_056194                                                              15    9605
NP_001152963                                                           15    9605
NP_001092264                                                           15    9605
NP_115503                                                              15    9605
XP_005253214                                                           15    9605
XP_006718406                                                           15    9605
XP_006718405                                                           15    9605
XP_005250309                                                           15    9605
XP_005250308                                                           15    9605
>XP_006725230
          Length = 2636

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   TVTRSLL 9
           TVTRSLL
Sbjct: 94  TVTRSLL 100
>XP_006720283
          Length = 2636

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   TVTRSLL 9
           TVTRSLL
Sbjct: 94  TVTRSLL 100
>NP_001193949
          Length = 397

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RTVTRSL 8
           RTVTR+L
Sbjct: 173 RTVTRAL 179
>XP_006724319
          Length = 452

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RTVTRSL 8
           RTVTR+L
Sbjct: 173 RTVTRAL 179
>XP_006724318
          Length = 456

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RTVTRSL 8
           RTVTR+L
Sbjct: 173 RTVTRAL 179
>XP_006724317
          Length = 492

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RTVTRSL 8
           RTVTR+L
Sbjct: 173 RTVTRAL 179
>NP_056194
          Length = 125

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  SRTVTR 6
          SRTVTR
Sbjct: 61 SRTVTR 66
>NP_001152963
          Length = 98

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  SRTVTR 6
          SRTVTR
Sbjct: 61 SRTVTR 66
>NP_001092264
          Length = 972

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SRTVTRSLL 9
           SRT  RSLL
Sbjct: 590 SRTKKRSLL 598
>NP_115503
          Length = 986

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SRTVTRSLL 9
           SRT  RSLL
Sbjct: 604 SRTKKRSLL 612
>XP_005253214
          Length = 854

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SRTVTRSLL 9
           SRT  RSLL
Sbjct: 590 SRTKKRSLL 598
>XP_006718406
          Length = 986

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SRTVTRSLL 9
           SRT  RSLL
Sbjct: 604 SRTKKRSLL 612
>XP_006718405
          Length = 986

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SRTVTRSLL 9
           SRT  RSLL
Sbjct: 604 SRTKKRSLL 612
>XP_005250309
          Length = 105

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  SRTVTR 6
          SRTVTR
Sbjct: 61 SRTVTR 66
>XP_005250308
          Length = 105

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  SRTVTR 6
          SRTVTR
Sbjct: 61 SRTVTR 66
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.321    0.124    0.289 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 274,627
Number of extensions: 234
Number of successful extensions: 15
Number of sequences better than 10000.0: 15
Number of HSP's gapped: 15
Number of HSP's successfully gapped: 15
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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