Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001895                                                              19     665
NP_001091680                                                           19     665
NP_001091679                                                           19     665
XP_006713048                                                           19     665
XP_006713047                                                           19     665
XP_006713046                                                           19     665
XP_005264943                                                           19     665
NP_001138565                                                           16    5631
NP_001138554                                                           16    5631
NP_001138555                                                           16    5631
NP_060639                                                              16    5631
XP_006719162                                                           16    5631
XP_005253462                                                           16    5631
XP_006713176                                                           16    5631
XP_006713175                                                           16    5631
NP_001600                                                              16    7355
NP_001888                                                              16    7355
NP_001121084                                                           15    9605
NP_945328                                                              15    9605
NP_945353                                                              15    9605
NP_004697                                                              15    9605
NP_000271                                                              15    9605
NP_001245394                                                           15    9605
NP_001245393                                                           15    9605
NP_001245391                                                           15    9605
NP_001245392                                                           15    9605
NP_001595                                                              15    9605
NP_075384                                                              15    9605
NP_001157207                                                           15    9605
XP_006725418                                                           15    9605
XP_006725417                                                           15    9605
XP_006725416                                                           15    9605
XP_006725415                                                           15    9605
XP_006725414                                                           15    9605
XP_006723526                                                           15    9605
XP_005259447                                                           15    9605
XP_005259446                                                           15    9605
XP_005259445                                                           15    9605
XP_005259444                                                           15    9605
XP_005259443                                                           15    9605
XP_005257754                                                           15    9605
XP_005257753                                                           15    9605
XP_006722172                                                           15    9605
XP_006722171                                                           15    9605
XP_006722170                                                           15    9605
XP_005253015                                                           15    9605
XP_006718309                                                           15    9605
XP_006718308                                                           15    9605
XP_006718307                                                           15    9605
XP_005253014                                                           15    9605
XP_005253013                                                           15    9605
XP_005253012                                                           15    9605
XP_005253011                                                           15    9605
>NP_001895
          Length = 781

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  SQSFAQEQV 9
          SQSF QEQV
Sbjct: 71 SQSFTQEQV 79
>NP_001091680
          Length = 781

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  SQSFAQEQV 9
          SQSF QEQV
Sbjct: 71 SQSFTQEQV 79
>NP_001091679
          Length = 781

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  SQSFAQEQV 9
          SQSF QEQV
Sbjct: 71 SQSFTQEQV 79
>XP_006713048
          Length = 720

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  SQSFAQEQV 9
          SQSF QEQV
Sbjct: 71 SQSFTQEQV 79
>XP_006713047
          Length = 774

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  SQSFAQEQV 9
          SQSF QEQV
Sbjct: 64 SQSFTQEQV 72
>XP_006713046
          Length = 774

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  SQSFAQEQV 9
          SQSF QEQV
Sbjct: 64 SQSFTQEQV 72
>XP_005264943
          Length = 781

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  SQSFAQEQV 9
          SQSF QEQV
Sbjct: 71 SQSFTQEQV 79
>NP_001138565
          Length = 576

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QSFAQEQV 9
           Q FA+EQV
Sbjct: 195 QGFAKEQV 202
>NP_001138554
          Length = 616

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QSFAQEQV 9
           Q FA+EQV
Sbjct: 235 QGFAKEQV 242
>NP_001138555
          Length = 532

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QSFAQEQV 9
           Q FA+EQV
Sbjct: 151 QGFAKEQV 158
>NP_060639
          Length = 1747

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SQSFAQEQV 9
           +QSF+++QV
Sbjct: 187 NQSFSEQQV 195
>XP_006719162
          Length = 1676

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SQSFAQEQV 9
           +QSF+++QV
Sbjct: 187 NQSFSEQQV 195
>XP_005253462
          Length = 1747

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SQSFAQEQV 9
           +QSF+++QV
Sbjct: 187 NQSFSEQQV 195
>XP_006713176
          Length = 531

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QSFAQEQV 9
           Q FA+EQV
Sbjct: 150 QGFAKEQV 157
>XP_006713175
          Length = 575

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QSFAQEQV 9
           Q FA+EQV
Sbjct: 194 QGFAKEQV 201
>NP_001600
          Length = 432

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  QSFAQEQV 9
          + FAQEQ+
Sbjct: 69 KKFAQEQI 76
>NP_001888
          Length = 2322

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    QSFAQEQV 9
            QSF+QE V
Sbjct: 1306 QSFSQEAV 1313
>NP_001121084
          Length = 422

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   SFAQEQV 9
           SF QEQ+
Sbjct: 216 SFTQEQI 222
>NP_945328
          Length = 879

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QSFAQEQV 9
           QSFA EQ+
Sbjct: 486 QSFALEQL 493
>NP_945353
          Length = 927

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QSFAQEQV 9
           QSFA EQ+
Sbjct: 534 QSFALEQL 541
>NP_004697
          Length = 912

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QSFAQEQV 9
           QSFA EQ+
Sbjct: 519 QSFALEQL 526
>NP_000271
          Length = 422

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   SFAQEQV 9
           SF QEQ+
Sbjct: 216 SFTQEQI 222
>NP_001245394
          Length = 422

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   SFAQEQV 9
           SF QEQ+
Sbjct: 216 SFTQEQI 222
>NP_001245393
          Length = 422

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   SFAQEQV 9
           SF QEQ+
Sbjct: 216 SFTQEQI 222
>NP_001245391
          Length = 436

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   SFAQEQV 9
           SF QEQ+
Sbjct: 230 SFTQEQI 236
>NP_001245392
          Length = 436

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   SFAQEQV 9
           SF QEQ+
Sbjct: 230 SFTQEQI 236
>NP_001595
          Length = 436

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   SFAQEQV 9
           SF QEQ+
Sbjct: 230 SFTQEQI 236
>NP_075384
          Length = 709

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SQSFAQEQ 8
           SQS+ +EQ
Sbjct: 156 SQSYVEEQ 163
>NP_001157207
          Length = 970

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SQSFAQEQV 9
           +Q+F QE+V
Sbjct: 628 AQTFLQEEV 636
>XP_006725418
          Length = 705

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SQSFAQEQV 9
           +Q+F QE+V
Sbjct: 363 AQTFLQEEV 371
>XP_006725417
          Length = 725

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SQSFAQEQV 9
           +Q+F QE+V
Sbjct: 383 AQTFLQEEV 391
>XP_006725416
          Length = 808

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SQSFAQEQV 9
           +Q+F QE+V
Sbjct: 466 AQTFLQEEV 474
>XP_006725415
          Length = 990

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SQSFAQEQV 9
           +Q+F QE+V
Sbjct: 648 AQTFLQEEV 656
>XP_006725414
          Length = 1034

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SQSFAQEQV 9
           +Q+F QE+V
Sbjct: 692 AQTFLQEEV 700
>XP_006723526
          Length = 693

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QSFAQEQV 9
           QSFA EQ+
Sbjct: 594 QSFALEQL 601
>XP_005259447
          Length = 981

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QSFAQEQV 9
           QSFA EQ+
Sbjct: 534 QSFALEQL 541
>XP_005259446
          Length = 987

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QSFAQEQV 9
           QSFA EQ+
Sbjct: 594 QSFALEQL 601
>XP_005259445
          Length = 1026

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QSFAQEQV 9
           QSFA EQ+
Sbjct: 579 QSFALEQL 586
>XP_005259444
          Length = 1037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QSFAQEQV 9
           QSFA EQ+
Sbjct: 590 QSFALEQL 597
>XP_005259443
          Length = 1041

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QSFAQEQV 9
           QSFA EQ+
Sbjct: 594 QSFALEQL 601
>XP_005257754
          Length = 705

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SQSFAQEQV 9
           +Q+F QE+V
Sbjct: 363 AQTFLQEEV 371
>XP_005257753
          Length = 707

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SQSFAQEQV 9
           +Q+F QE+V
Sbjct: 365 AQTFLQEEV 373
>XP_006722172
          Length = 808

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SQSFAQEQV 9
           +Q+F QE+V
Sbjct: 466 AQTFLQEEV 474
>XP_006722171
          Length = 972

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SQSFAQEQV 9
           +Q+F QE+V
Sbjct: 630 AQTFLQEEV 638
>XP_006722170
          Length = 1016

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SQSFAQEQV 9
           +Q+F QE+V
Sbjct: 674 AQTFLQEEV 682
>XP_005253015
          Length = 286

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  SFAQEQV 9
          SF QEQ+
Sbjct: 80 SFTQEQI 86
>XP_006718309
          Length = 355

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   SFAQEQV 9
           SF QEQ+
Sbjct: 149 SFTQEQI 155
>XP_006718308
          Length = 369

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   SFAQEQV 9
           SF QEQ+
Sbjct: 163 SFTQEQI 169
>XP_006718307
          Length = 377

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   SFAQEQV 9
           SF QEQ+
Sbjct: 171 SFTQEQI 177
>XP_005253014
          Length = 415

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   SFAQEQV 9
           SF QEQ+
Sbjct: 230 SFTQEQI 236
>XP_005253013
          Length = 422

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   SFAQEQV 9
           SF QEQ+
Sbjct: 216 SFTQEQI 222
>XP_005253012
          Length = 422

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   SFAQEQV 9
           SF QEQ+
Sbjct: 216 SFTQEQI 222
>XP_005253011
          Length = 436

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   SFAQEQV 9
           SF QEQ+
Sbjct: 230 SFTQEQI 236
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.301    0.106    0.239 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 445,855
Number of extensions: 801
Number of successful extensions: 53
Number of sequences better than 10000.0: 53
Number of HSP's gapped: 53
Number of HSP's successfully gapped: 53
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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