Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              20     390
NP_671714                                                              20     390
XP_006715890                                                           20     390
XP_005250160                                                           20     390
XP_005250159                                                           20     390
NP_570925                                                              17    2528
NP_570924                                                              17    2528
NP_570923                                                              17    2528
NP_002841                                                              17    2528
XP_006722884                                                           17    2528
XP_005259667                                                           17    2528
XP_005259666                                                           17    2528
XP_006722883                                                           17    2528
XP_006722882                                                           17    2528
XP_006722881                                                           17    2528
XP_005259664                                                           17    2528
XP_005259663                                                           17    2528
XP_006722880                                                           17    2528
XP_006722879                                                           17    2528
XP_006722878                                                           17    2528
XP_006722877                                                           17    2528
XP_006722876                                                           17    2528
XP_006722875                                                           17    2528
XP_005259658                                                           17    2528
XP_005259657                                                           17    2528
XP_006722874                                                           17    2528
XP_006722873                                                           17    2528
XP_006722872                                                           17    2528
XP_006722871                                                           17    2528
NP_001180416                                                           15    9605
NP_006863                                                              15    9605
NP_001185523                                                           15    9605
NP_758515                                                              15    9605
NP_004220                                                              15    9605
NP_835368                                                              15    9605
NP_001185522                                                           15    9605
NP_835369                                                              15    9605
NP_004471                                                              15    9605
NP_060493                                                              15    9605
NP_569707                                                              15    9605
NP_002831                                                              15    9605
XP_005272757                                                           15    9605
XP_005272756                                                           15    9605
XP_005257998                                                           15    9605
XP_006720160                                                           15    9605
XP_006720159                                                           15    9605
XP_006713751                                                           15    9605
XP_005247655                                                           15    9605
XP_005247654                                                           15    9605
XP_006710864                                                           15    9605
XP_005271139                                                           15    9605
XP_006710863                                                           15    9605
XP_006710862                                                           15    9605
XP_006710861                                                           15    9605
XP_005271138                                                           15    9605
XP_006710860                                                           15    9605
XP_006710859                                                           15    9605
XP_005271137                                                           15    9605
XP_006710858                                                           15    9605
XP_005271136                                                           15    9605
NP_001138424                                                           15    9605
>NP_005742
          Length = 3907

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   SQKIETIQF 9
           SQKIET+QF
Sbjct: 675 SQKIETMQF 683
>NP_671714
          Length = 3899

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   SQKIETIQF 9
           SQKIET+QF
Sbjct: 675 SQKIETMQF 683
>XP_006715890
          Length = 3860

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   SQKIETIQF 9
           SQKIET+QF
Sbjct: 675 SQKIETMQF 683
>XP_005250160
          Length = 3939

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   SQKIETIQF 9
           SQKIET+QF
Sbjct: 675 SQKIETMQF 683
>XP_005250159
          Length = 3952

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   SQKIETIQF 9
           SQKIET+QF
Sbjct: 675 SQKIETMQF 683
>NP_570925
          Length = 1505

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SQKIETIQF 9
          SQ+ ETI+F
Sbjct: 75 SQRFETIEF 83
>NP_570924
          Length = 1910

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SQKIETIQF 9
          SQ+ ETI+F
Sbjct: 75 SQRFETIEF 83
>NP_570923
          Length = 1501

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SQKIETIQF 9
          SQ+ ETI+F
Sbjct: 75 SQRFETIEF 83
>NP_002841
          Length = 1948

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SQKIETIQF 9
          SQ+ ETI+F
Sbjct: 75 SQRFETIEF 83
>XP_006722884
          Length = 1490

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SQKIETIQF 9
          SQ+ ETI+F
Sbjct: 75 SQRFETIEF 83
>XP_005259667
          Length = 1497

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SQKIETIQF 9
          SQ+ ETI+F
Sbjct: 75 SQRFETIEF 83
>XP_005259666
          Length = 1501

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SQKIETIQF 9
          SQ+ ETI+F
Sbjct: 75 SQRFETIEF 83
>XP_006722883
          Length = 1510

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SQKIETIQF 9
          SQ+ ETI+F
Sbjct: 75 SQRFETIEF 83
>XP_006722882
          Length = 1522

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SQKIETIQF 9
          SQ+ ETI+F
Sbjct: 75 SQRFETIEF 83
>XP_006722881
          Length = 1526

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SQKIETIQF 9
          SQ+ ETI+F
Sbjct: 75 SQRFETIEF 83
>XP_005259664
          Length = 1906

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SQKIETIQF 9
          SQ+ ETI+F
Sbjct: 75 SQRFETIEF 83
>XP_005259663
          Length = 1910

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SQKIETIQF 9
          SQ+ ETI+F
Sbjct: 75 SQRFETIEF 83
>XP_006722880
          Length = 1915

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SQKIETIQF 9
          SQ+ ETI+F
Sbjct: 75 SQRFETIEF 83
>XP_006722879
          Length = 1917

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SQKIETIQF 9
          SQ+ ETI+F
Sbjct: 75 SQRFETIEF 83
>XP_006722878
          Length = 1924

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SQKIETIQF 9
          SQ+ ETI+F
Sbjct: 75 SQRFETIEF 83
>XP_006722877
          Length = 1928

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SQKIETIQF 9
          SQ+ ETI+F
Sbjct: 75 SQRFETIEF 83
>XP_006722876
          Length = 1933

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SQKIETIQF 9
          SQ+ ETI+F
Sbjct: 75 SQRFETIEF 83
>XP_006722875
          Length = 1935

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SQKIETIQF 9
          SQ+ ETI+F
Sbjct: 75 SQRFETIEF 83
>XP_005259658
          Length = 1935

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SQKIETIQF 9
          SQ+ ETI+F
Sbjct: 75 SQRFETIEF 83
>XP_005259657
          Length = 1935

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SQKIETIQF 9
          SQ+ ETI+F
Sbjct: 75 SQRFETIEF 83
>XP_006722874
          Length = 1940

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SQKIETIQF 9
          SQ+ ETI+F
Sbjct: 75 SQRFETIEF 83
>XP_006722873
          Length = 1944

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SQKIETIQF 9
          SQ+ ETI+F
Sbjct: 75 SQRFETIEF 83
>XP_006722872
          Length = 1944

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SQKIETIQF 9
          SQ+ ETI+F
Sbjct: 75 SQRFETIEF 83
>XP_006722871
          Length = 1944

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SQKIETIQF 9
          SQ+ ETI+F
Sbjct: 75 SQRFETIEF 83
>NP_001180416
          Length = 444

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SQKIETI 7
           SQ+IET+
Sbjct: 153 SQRIETV 159
>NP_006863
          Length = 478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SQKIETI 7
           SQ+IET+
Sbjct: 187 SQRIETV 193
>NP_001185523
          Length = 1135

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SQKIETI 7
           SQ+IET+
Sbjct: 844 SQRIETV 850
>NP_758515
          Length = 1182

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SQKIETI 7
           SQ+IET+
Sbjct: 891 SQRIETV 897
>NP_004220
          Length = 1454

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  QKIETIQF 9
          +KIE +QF
Sbjct: 81 RKIEIVQF 88
>NP_835368
          Length = 575

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   QKIETIQF 9
           +KIET+++
Sbjct: 560 EKIETVKY 567
>NP_001185522
          Length = 1158

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   SQKIETI 7
           SQ+IET+
Sbjct: 891 SQRIETV 897
>NP_835369
          Length = 575

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   QKIETIQF 9
           +KIET+++
Sbjct: 560 EKIETVKY 567
>NP_004471
          Length = 412

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   QKIETIQF 9
           +KIET+++
Sbjct: 397 EKIETVKY 404
>NP_060493
          Length = 1422

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  QKIETI 7
          QKIETI
Sbjct: 40 QKIETI 45
>NP_569707
          Length = 1898

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SQKIETIQF 9
          SQ+ E I+F
Sbjct: 75 SQRFEVIEF 83
>NP_002831
          Length = 1907

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SQKIETIQF 9
          SQ+ E I+F
Sbjct: 75 SQRFEVIEF 83
>XP_005272757
          Length = 1410

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  QKIETIQF 9
          +KIE +QF
Sbjct: 81 RKIEIVQF 88
>XP_005272756
          Length = 1443

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  QKIETIQF 9
          +KIE +QF
Sbjct: 81 RKIEIVQF 88
>XP_005257998
          Length = 733

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QKIETIQF 9
           QK+ T+QF
Sbjct: 665 QKLFTVQF 672
>XP_006720160
          Length = 575

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   QKIETIQF 9
           +KIET+++
Sbjct: 560 EKIETVKY 567
>XP_006720159
          Length = 575

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   QKIETIQF 9
           +KIET+++
Sbjct: 560 EKIETVKY 567
>XP_006713751
          Length = 1423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  QKIETI 7
          QKIETI
Sbjct: 40 QKIETI 45
>XP_005247655
          Length = 1423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  QKIETI 7
          QKIETI
Sbjct: 40 QKIETI 45
>XP_005247654
          Length = 1423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  QKIETI 7
          QKIETI
Sbjct: 40 QKIETI 45
>XP_006710864
          Length = 1729

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SQKIETIQF 9
          SQ+ E I+F
Sbjct: 75 SQRFEVIEF 83
>XP_005271139
          Length = 1796

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SQKIETIQF 9
          SQ+ E I+F
Sbjct: 75 SQRFEVIEF 83
>XP_006710863
          Length = 1811

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SQKIETIQF 9
          SQ+ E I+F
Sbjct: 75 SQRFEVIEF 83
>XP_006710862
          Length = 1820

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SQKIETIQF 9
          SQ+ E I+F
Sbjct: 75 SQRFEVIEF 83
>XP_006710861
          Length = 1902

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SQKIETIQF 9
          SQ+ E I+F
Sbjct: 75 SQRFEVIEF 83
>XP_005271138
          Length = 1909

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SQKIETIQF 9
          SQ+ E I+F
Sbjct: 75 SQRFEVIEF 83
>XP_006710860
          Length = 1911

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SQKIETIQF 9
          SQ+ E I+F
Sbjct: 75 SQRFEVIEF 83
>XP_006710859
          Length = 1913

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SQKIETIQF 9
          SQ+ E I+F
Sbjct: 75 SQRFEVIEF 83
>XP_005271137
          Length = 1918

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SQKIETIQF 9
          SQ+ E I+F
Sbjct: 75 SQRFEVIEF 83
>XP_006710858
          Length = 1922

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SQKIETIQF 9
          SQ+ E I+F
Sbjct: 75 SQRFEVIEF 83
>XP_005271136
          Length = 1922

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SQKIETIQF 9
          SQ+ E I+F
Sbjct: 75 SQRFEVIEF 83
>NP_001138424
          Length = 2172

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    SQKIETIQ 8
            S+KI+T+Q
Sbjct: 1086 SRKIQTLQ 1093
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.317    0.128    0.309 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 344,599
Number of extensions: 476
Number of successful extensions: 61
Number of sequences better than 10000.0: 61
Number of HSP's gapped: 61
Number of HSP's successfully gapped: 61
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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