Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

XP_006712163                                                           17    3301
XP_005264606                                                           17    3301
XP_006712161                                                           17    3301
XP_005264605                                                           17    3301
XP_005264604                                                           17    3301
NP_208382                                                              17    3301
NP_001137357                                                           17    4312
NP_001137358                                                           17    4312
NP_001231921                                                           17    4312
NP_001231919                                                           17    4312
NP_002471                                                              17    4312
XP_005268950                                                           17    4312
XP_005268949                                                           17    4312
XP_005268948                                                           17    4312
XP_005268946                                                           17    4312
XP_005268944                                                           17    4312
XP_005268945                                                           17    4312
XP_005268943                                                           17    4312
XP_005268942                                                           17    4312
NP_005261                                                              16    5631
NP_001073964                                                           16    5631
NP_258428                                                              16    5631
NP_056078                                                              16    5631
NP_001167587                                                           16    5631
NP_001167588                                                           16    5631
NP_005169                                                              16    5631
NP_387467                                                              16    5631
XP_005259186                                                           16    5631
XP_005254315                                                           16    5631
XP_005254314                                                           16    5631
XP_006720509                                                           16    5631
XP_005254313                                                           16    5631
XP_005254312                                                           16    5631
XP_005269291                                                           16    5631
XP_006715861                                                           16    5631
XP_006715860                                                           16    5631
XP_006712486                                                           16    5631
XP_006712485                                                           16    5631
NP_065750                                                              16    7355
NP_115791                                                              16    7355
NP_690851                                                              16    7355
NP_001156794                                                           16    7355
NP_001156793                                                           16    7355
XP_005255298                                                           16    7355
XP_006715858                                                           16    7355
XP_006715857                                                           16    7355
XP_005245421                                                           16    7355
XP_006711532                                                           16    7355
XP_005245420                                                           16    7355
NP_001012986                                                           16    7355
NP_001001890                                                           15    9605
NP_001745                                                              15    9605
NP_001231933                                                           15    9605
NP_001159845                                                           15    9605
NP_005588                                                              15    9605
NP_542399                                                              15    9605
NP_060393                                                              15    9605
NP_001231931                                                           15    9605
NP_995315                                                              15    9605
NP_001231934                                                           15    9605
XP_005261126                                                           15    9605
XP_005261125                                                           15    9605
XP_005259621                                                           15    9605
XP_006722822                                                           15    9605
XP_005259620                                                           15    9605
XP_006718491                                                           15    9605
XP_005273791                                                           15    9605
XP_005273790                                                           15    9605
XP_006714311                                                           15    9605
XP_006714310                                                           15    9605
>XP_006712163
          Length = 363

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   PRLSSRLS 9
           PRLS RLS
Sbjct: 300 PRLSPRLS 307
>XP_005264606
          Length = 399

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   PRLSSRLS 9
           PRLS RLS
Sbjct: 336 PRLSPRLS 343
>XP_006712161
          Length = 399

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   PRLSSRLS 9
           PRLS RLS
Sbjct: 336 PRLSPRLS 343
>XP_005264605
          Length = 407

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   PRLSSRLS 9
           PRLS RLS
Sbjct: 344 PRLSPRLS 351
>XP_005264604
          Length = 412

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   PRLSSRLS 9
           PRLS RLS
Sbjct: 349 PRLSPRLS 356
>NP_208382
          Length = 648

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  SPRLSSRL 8
          SPRL SRL
Sbjct: 36 SPRLRSRL 43
>NP_001137357
          Length = 1030

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SPRLSSRL 8
           SPRLSS L
Sbjct: 473 SPRLSSSL 480
>NP_001137358
          Length = 943

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SPRLSSRL 8
           SPRLSS L
Sbjct: 386 SPRLSSSL 393
>NP_001231921
          Length = 974

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SPRLSSRL 8
           SPRLSS L
Sbjct: 473 SPRLSSSL 480
>NP_001231919
          Length = 995

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SPRLSSRL 8
           SPRLSS L
Sbjct: 473 SPRLSSSL 480
>NP_002471
          Length = 1030

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SPRLSSRL 8
           SPRLSS L
Sbjct: 473 SPRLSSSL 480
>XP_005268950
          Length = 931

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SPRLSSRL 8
           SPRLSS L
Sbjct: 473 SPRLSSSL 480
>XP_005268949
          Length = 987

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SPRLSSRL 8
           SPRLSS L
Sbjct: 473 SPRLSSSL 480
>XP_005268948
          Length = 990

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SPRLSSRL 8
           SPRLSS L
Sbjct: 473 SPRLSSSL 480
>XP_005268946
          Length = 999

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SPRLSSRL 8
           SPRLSS L
Sbjct: 473 SPRLSSSL 480
>XP_005268944
          Length = 1005

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SPRLSSRL 8
           SPRLSS L
Sbjct: 473 SPRLSSSL 480
>XP_005268945
          Length = 1005

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SPRLSSRL 8
           SPRLSS L
Sbjct: 473 SPRLSSSL 480
>XP_005268943
          Length = 1034

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SPRLSSRL 8
           SPRLSS L
Sbjct: 473 SPRLSSSL 480
>XP_005268942
          Length = 1046

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SPRLSSRL 8
           SPRLSS L
Sbjct: 473 SPRLSSSL 480
>NP_005261
          Length = 1586

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SPRLSSRLS 9
           SPR++ RLS
Sbjct: 220 SPRVTPRLS 228
>NP_001073964
          Length = 2968

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   PRLSSRLS 9
           PRL+ RLS
Sbjct: 256 PRLAERLS 263
>NP_258428
          Length = 779

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  PRLSSRL 8
          PRL+SRL
Sbjct: 56 PRLASRL 62
>NP_056078
          Length = 3036

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SPRLSSRLS 9
           SPR  SRLS
Sbjct: 473 SPRTYSRLS 481
>NP_001167587
          Length = 3037

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SPRLSSRLS 9
           SPR  SRLS
Sbjct: 473 SPRTYSRLS 481
>NP_001167588
          Length = 2400

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SPRLSSRLS 9
           SPR  SRLS
Sbjct: 473 SPRTYSRLS 481
>NP_005169
          Length = 454

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SPRLSSRLS 9
           SP  SSRLS
Sbjct: 382 SPESSSRLS 390
>NP_387467
          Length = 1087

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    SPRLSSRL 8
            SP++SSRL
Sbjct: 1058 SPQVSSRL 1065
>XP_005259186
          Length = 650

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SPRLSSRLS 9
           SP  SSRLS
Sbjct: 578 SPESSSRLS 586
>XP_005254315
          Length = 2576

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SPRLSSRLS 9
           SPR  SRLS
Sbjct: 473 SPRTYSRLS 481
>XP_005254314
          Length = 2605

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SPRLSSRLS 9
           SPR  SRLS
Sbjct: 473 SPRTYSRLS 481
>XP_006720509
          Length = 2646

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SPRLSSRLS 9
           SPR  SRLS
Sbjct: 473 SPRTYSRLS 481
>XP_005254313
          Length = 3057

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SPRLSSRLS 9
           SPR  SRLS
Sbjct: 473 SPRTYSRLS 481
>XP_005254312
          Length = 3058

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SPRLSSRLS 9
           SPR  SRLS
Sbjct: 473 SPRTYSRLS 481
>XP_005269291
          Length = 1087

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    SPRLSSRL 8
            SP++SSRL
Sbjct: 1058 SPQVSSRL 1065
>XP_006715861
          Length = 2189

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   PRLSSRLS 9
           PRL+ RLS
Sbjct: 256 PRLAERLS 263
>XP_006715860
          Length = 2968

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   PRLSSRLS 9
           PRL+ RLS
Sbjct: 256 PRLAERLS 263
>XP_006712486
          Length = 1504

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SPRLSSRLS 9
           SPR++ RLS
Sbjct: 155 SPRVTPRLS 163
>XP_006712485
          Length = 1569

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SPRLSSRLS 9
           SPR++ RLS
Sbjct: 220 SPRVTPRLS 228
>NP_065750
          Length = 593

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SPRLSSRL 8
           SPR SSR+
Sbjct: 135 SPRSSSRM 142
>NP_115791
          Length = 1154

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   PRLSSRLS 9
           PR+S RLS
Sbjct: 883 PRVSPRLS 890
>NP_690851
          Length = 280

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  PRLSSRL 8
          PR+SSR+
Sbjct: 31 PRMSSRI 37
>NP_001156794
          Length = 649

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   PRLSSRLS 9
           P LS+RLS
Sbjct: 621 PELSARLS 628
>NP_001156793
          Length = 696

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   PRLSSRLS 9
           P LS+RLS
Sbjct: 668 PELSARLS 675
>XP_005255298
          Length = 280

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  PRLSSRL 8
          PR+SSR+
Sbjct: 31 PRMSSRI 37
>XP_006715858
          Length = 1267

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    PRLSSRLS 9
            PR+S RLS
Sbjct: 996  PRVSPRLS 1003
>XP_006715857
          Length = 1268

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    PRLSSRLS 9
            PR+S RLS
Sbjct: 997  PRVSPRLS 1004
>XP_005245421
          Length = 593

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SPRLSSRL 8
           SPR SSR+
Sbjct: 135 SPRSSSRM 142
>XP_006711532
          Length = 593

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SPRLSSRL 8
           SPR SSR+
Sbjct: 135 SPRSSSRM 142
>XP_005245420
          Length = 599

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SPRLSSRL 8
           SPR SSR+
Sbjct: 141 SPRSSSRM 148
>NP_001012986
          Length = 249

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SPRLSSRLS 9
           +PR+ SRL+
Sbjct: 107 TPRIDSRLA 115
>NP_001001890
          Length = 453

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SPRLSSRLS 9
           S  LSSRLS
Sbjct: 287 SAELSSRLS 295
>NP_001745
          Length = 480

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SPRLSSRLS 9
           S  LSSRLS
Sbjct: 314 SAELSSRLS 322
>NP_001231933
          Length = 439

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SPRLSS 6
           SPRLSS
Sbjct: 343 SPRLSS 348
>NP_001159845
          Length = 289

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  SPRLSSRLS 9
          +PR  SRLS
Sbjct: 63 APRSQSRLS 71
>NP_005588
          Length = 428

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SPRLSS 6
           SPRLSS
Sbjct: 343 SPRLSS 348
>NP_542399
          Length = 252

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  SPRLSSRLS 9
          SPR S R+S
Sbjct: 75 SPRRSPRIS 83
>NP_060393
          Length = 272

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  SPRLSSRLS 9
          +PR  SRLS
Sbjct: 46 APRSQSRLS 54
>NP_001231931
          Length = 508

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SPRLSS 6
           SPRLSS
Sbjct: 343 SPRLSS 348
>NP_995315
          Length = 499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SPRLSS 6
           SPRLSS
Sbjct: 334 SPRLSS 339
>NP_001231934
          Length = 430

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SPRLSS 6
           SPRLSS
Sbjct: 334 SPRLSS 339
>XP_005261126
          Length = 416

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SPRLSSRLS 9
           S  LSSRLS
Sbjct: 250 SAELSSRLS 258
>XP_005261125
          Length = 468

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SPRLSSRLS 9
           S  LSSRLS
Sbjct: 302 SAELSSRLS 310
>XP_005259621
          Length = 511

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SPRLSS 6
           SPRLSS
Sbjct: 343 SPRLSS 348
>XP_006722822
          Length = 526

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SPRLSS 6
           SPRLSS
Sbjct: 334 SPRLSS 339
>XP_005259620
          Length = 535

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   SPRLSS 6
           SPRLSS
Sbjct: 343 SPRLSS 348
>XP_006718491
          Length = 408

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  SPRLSSRLS 9
          SPR S R+S
Sbjct: 75 SPRRSPRIS 83
>XP_005273791
          Length = 441

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  SPRLSSRLS 9
          SPR S R+S
Sbjct: 75 SPRRSPRIS 83
>XP_005273790
          Length = 467

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  SPRLSSRLS 9
          SPR S R+S
Sbjct: 75 SPRRSPRIS 83
>XP_006714311
          Length = 289

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  SPRLSSRLS 9
          +PR  SRLS
Sbjct: 63 APRSQSRLS 71
>XP_006714310
          Length = 367

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  SPRLSSRLS 9
          +PR  SRLS
Sbjct: 63 APRSQSRLS 71
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.307    0.117    0.288 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 470,937
Number of extensions: 757
Number of successful extensions: 70
Number of sequences better than 10000.0: 70
Number of HSP's gapped: 70
Number of HSP's successfully gapped: 70
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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