Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005350                                                              20     299
NP_005718                                                              17    3301
NP_065853                                                              16    5631
NP_689526                                                              16    5631
NP_699177                                                              16    5631
NP_001273068                                                           16    5631
XP_005271684                                                           16    5631
XP_005271472                                                           16    5631
XP_005271471                                                           16    5631
XP_005271470                                                           16    5631
XP_005271469                                                           16    5631
XP_006718826                                                           16    5631
XP_006718825                                                           16    5631
NP_689800                                                              16    5631
NP_001017969                                                           16    7355
NP_005378                                                              16    7355
NP_001275915                                                           16    7355
NP_001275914                                                           16    7355
NP_009099                                                              16    7355
XP_005256997                                                           16    7355
XP_005256995                                                           16    7355
XP_006718305                                                           16    7355
XP_005253007                                                           16    7355
XP_006716793                                                           16    7355
XP_005251442                                                           16    7355
NP_036421                                                              15    9605
NP_987096                                                              15    9605
NP_003830                                                              15    9605
NP_001265197                                                           15    9605
NP_055641                                                              15    9605
NP_003598                                                              15    9605
NP_005294                                                              15    9605
XP_005260231                                                           15    9605
XP_005260230                                                           15    9605
XP_005266834                                                           15    9605
XP_006711900                                                           15    9605
XP_005273381                                                           15    9605
XP_005273380                                                           15    9605
XP_005273379                                                           15    9605
XP_006711899                                                           15    9605
XP_005273378                                                           15    9605
XP_005273377                                                           15    9605
XP_006711898                                                           15    9605
XP_006711897                                                           15    9605
XP_005273375                                                           15    9605
XP_005273374                                                           15    9605
>NP_005350
          Length = 552

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   SNATNTANF 9
           SNAT+TANF
Sbjct: 206 SNATSTANF 214
>NP_005718
          Length = 241

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   NATNTAN 8
           N TNTAN
Sbjct: 178 NVTNTAN 184
>NP_065853
          Length = 1117

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ATNTAN 8
           ATNTAN
Sbjct: 360 ATNTAN 365
>NP_689526
          Length = 504

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SNATNTAN 8
           SN+TN++N
Sbjct: 193 SNSTNSSN 200
>NP_699177
          Length = 799

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NATNTANF 9
           N+T TAN+
Sbjct: 314 NSTETANY 321
>NP_001273068
          Length = 369

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  SNATNTAN 8
          SN+TN++N
Sbjct: 58 SNSTNSSN 65
>XP_005271684
          Length = 1081

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ATNTAN 8
           ATNTAN
Sbjct: 360 ATNTAN 365
>XP_005271472
          Length = 273

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   NATNTANF 9
           N TNT NF
Sbjct: 235 NWTNTLNF 242
>XP_005271471
          Length = 273

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   NATNTANF 9
           N TNT NF
Sbjct: 235 NWTNTLNF 242
>XP_005271470
          Length = 282

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   NATNTANF 9
           N TNT NF
Sbjct: 204 NWTNTLNF 211
>XP_005271469
          Length = 295

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   NATNTANF 9
           N TNT NF
Sbjct: 217 NWTNTLNF 224
>XP_006718826
          Length = 345

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SNATNTAN 8
           SN+TN++N
Sbjct: 193 SNSTNSSN 200
>XP_006718825
          Length = 398

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  SNATNTAN 8
          SN+TN++N
Sbjct: 87 SNSTNSSN 94
>NP_689800
          Length = 313

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   NATNTANF 9
           N TNT NF
Sbjct: 235 NWTNTLNF 242
>NP_001017969
          Length = 2103

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    TNTANF 9
            TNT+NF
Sbjct: 1821 TNTSNF 1826
>NP_005378
          Length = 937

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TNTANF 9
           TNT+NF
Sbjct: 403 TNTSNF 408
>NP_001275915
          Length = 1616

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    SNATNTANF 9
            +NA N+ NF
Sbjct: 1261 ANALNSTNF 1269
>NP_001275914
          Length = 1621

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    SNATNTANF 9
            +NA N+ NF
Sbjct: 1266 ANALNSTNF 1274
>NP_009099
          Length = 1581

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    SNATNTANF 9
            +NA N+ NF
Sbjct: 1226 ANALNSTNF 1234
>XP_005256997
          Length = 1560

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    SNATNTANF 9
            +NA N+ NF
Sbjct: 1205 ANALNSTNF 1213
>XP_005256995
          Length = 1621

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    SNATNTANF 9
            +NA N+ NF
Sbjct: 1266 ANALNSTNF 1274
>XP_006718305
          Length = 1743

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TNTANF 9
           TNT+NF
Sbjct: 403 TNTSNF 408
>XP_005253007
          Length = 1817

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TNTANF 9
           TNT+NF
Sbjct: 403 TNTSNF 408
>XP_006716793
          Length = 1317

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    TNTANF 9
            TNT+NF
Sbjct: 1035 TNTSNF 1040
>XP_005251442
          Length = 2073

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    TNTANF 9
            TNT+NF
Sbjct: 1791 TNTSNF 1796
>NP_036421
          Length = 624

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   SNATNTANF 9
           SNA   ANF
Sbjct: 182 SNAIGIANF 190
>NP_987096
          Length = 624

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   SNATNTANF 9
           SNA   ANF
Sbjct: 182 SNAIGIANF 190
>NP_003830
          Length = 616

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ATNTANF 9
           +T+TANF
Sbjct: 270 STHTANF 276
>NP_001265197
          Length = 602

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ATNTANF 9
           +T+TANF
Sbjct: 256 STHTANF 262
>NP_055641
          Length = 1638

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SNATNTANF 9
           S+ T+T+NF
Sbjct: 363 SSPTDTSNF 371
>NP_003598
          Length = 1719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SNATNTANF 9
           S+ T+T+NF
Sbjct: 363 SSPTDTSNF 371
>NP_005294
          Length = 300

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NATNTANF 9
           NA+N A+F
Sbjct: 241 NASNVASF 248
>XP_005260231
          Length = 624

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   SNATNTANF 9
           SNA   ANF
Sbjct: 182 SNAIGIANF 190
>XP_005260230
          Length = 624

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   SNATNTANF 9
           SNA   ANF
Sbjct: 182 SNAIGIANF 190
>XP_005266834
          Length = 523

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ATNTANF 9
           +T+TANF
Sbjct: 270 STHTANF 276
>XP_006711900
          Length = 993

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SNATNTANF 9
           S+ T+T+NF
Sbjct: 363 SSPTDTSNF 371
>XP_005273381
          Length = 1732

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SNATNTANF 9
           S+ T+T+NF
Sbjct: 363 SSPTDTSNF 371
>XP_005273380
          Length = 1751

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SNATNTANF 9
           S+ T+T+NF
Sbjct: 363 SSPTDTSNF 371
>XP_005273379
          Length = 1754

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SNATNTANF 9
           S+ T+T+NF
Sbjct: 363 SSPTDTSNF 371
>XP_006711899
          Length = 1770

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SNATNTANF 9
           S+ T+T+NF
Sbjct: 363 SSPTDTSNF 371
>XP_005273378
          Length = 1781

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SNATNTANF 9
           S+ T+T+NF
Sbjct: 363 SSPTDTSNF 371
>XP_005273377
          Length = 1794

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SNATNTANF 9
           S+ T+T+NF
Sbjct: 363 SSPTDTSNF 371
>XP_006711898
          Length = 1797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SNATNTANF 9
           S+ T+T+NF
Sbjct: 363 SSPTDTSNF 371
>XP_006711897
          Length = 1816

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SNATNTANF 9
           S+ T+T+NF
Sbjct: 363 SSPTDTSNF 371
>XP_005273375
          Length = 1829

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SNATNTANF 9
           S+ T+T+NF
Sbjct: 363 SSPTDTSNF 371
>XP_005273374
          Length = 1832

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SNATNTANF 9
           S+ T+T+NF
Sbjct: 363 SSPTDTSNF 371
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.296    0.101    0.263 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 344,429
Number of extensions: 720
Number of successful extensions: 46
Number of sequences better than 10000.0: 46
Number of HSP's gapped: 46
Number of HSP's successfully gapped: 46
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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