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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004251                                                              19     869
NP_150094                                                              16    7355
NP_001106853                                                           16    7355
NP_443132                                                              16    7355
NP_006034                                                              16    7355
NP_937757                                                              16    7355
NP_937756                                                              16    7355
NP_004389                                                              16    7355
XP_006712889                                                           16    7355
NP_003310                                                              15    9605
NP_597676                                                              15    9605
NP_001243779                                                           15    9605
NP_596869                                                              15    9605
NP_932341                                                              15    9605
NP_940959                                                              15    9605
XP_005252834                                                           15    9605
XP_006725198                                                           15    9605
XP_006725197                                                           15    9605
XP_006725196                                                           15    9605
XP_006725195                                                           15    9605
XP_006725194                                                           15    9605
XP_006718198                                                           15    9605
XP_005252833                                                           15    9605
XP_006718197                                                           15    9605
XP_006718196                                                           15    9605
XP_006718195                                                           15    9605
XP_005252832                                                           15    9605
XP_005246888                                                           15    9605
XP_006712788                                                           15    9605
XP_006712787                                                           15    9605
XP_006712786                                                           15    9605
NP_001254479                                                           15    9605
NP_597681                                                              15    9605

>NP_004251
          Length = 1208

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SMDFLAVKR 9
           S DFLAVKR
Sbjct: 836 STDFLAVKR 844



>NP_150094
          Length = 3564

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   DFLAVK 8
           DFLAVK
Sbjct: 636 DFLAVK 641



>NP_001106853
          Length = 2093

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SMDFLAVKR 9
            +MD+LA +R
Sbjct: 1820 TMDYLAAER 1828



>NP_443132
          Length = 3538

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   DFLAVK 8
           DFLAVK
Sbjct: 669 DFLAVK 674



>NP_006034
          Length = 367

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   DFLAVKR 9
           DFL +KR
Sbjct: 290 DFLGIKR 296



>NP_937757
          Length = 3667

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   DFLAVK 8
           DFLAVK
Sbjct: 733 DFLAVK 738



>NP_937756
          Length = 3707

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   DFLAVK 8
           DFLAVK
Sbjct: 773 DFLAVK 778



>NP_004389
          Length = 875

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   DFLAVKR 9
           DFL VKR
Sbjct: 634 DFLKVKR 640



>XP_006712889
          Length = 2069

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    SMDFLAVKR 9
            +MD+LA +R
Sbjct: 1796 TMDYLAAER 1804



>NP_003310
          Length = 26926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     DFLAVKR 9
             D+LA+KR
Sbjct: 25604 DYLAMKR 25610



>NP_597676
          Length = 27051

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     DFLAVKR 9
             D+LA+KR
Sbjct: 25729 DYLAMKR 25735



>NP_001243779
          Length = 34350

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     DFLAVKR 9
             D+LA+KR
Sbjct: 33028 DYLAMKR 33034



>NP_596869
          Length = 33423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     DFLAVKR 9
             D+LA+KR
Sbjct: 32101 DYLAMKR 32107



>NP_932341
          Length = 542

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SMDFLAVK 8
           S D+LAVK
Sbjct: 246 SQDWLAVK 253



>NP_940959
          Length = 357

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   FLAVKR 9
           FLAVKR
Sbjct: 156 FLAVKR 161



>XP_005252834
          Length = 406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SMDFLAVK 8
           S D+LAVK
Sbjct: 246 SQDWLAVK 253



>XP_006725198
          Length = 483

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SMDFLAVK 8
           S D+LAVK
Sbjct: 246 SQDWLAVK 253



>XP_006725197
          Length = 537

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SMDFLAVK 8
           S D+LAVK
Sbjct: 246 SQDWLAVK 253



>XP_006725196
          Length = 542

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SMDFLAVK 8
           S D+LAVK
Sbjct: 246 SQDWLAVK 253



>XP_006725195
          Length = 542

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SMDFLAVK 8
           S D+LAVK
Sbjct: 246 SQDWLAVK 253



>XP_006725194
          Length = 542

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SMDFLAVK 8
           S D+LAVK
Sbjct: 246 SQDWLAVK 253



>XP_006718198
          Length = 406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SMDFLAVK 8
           S D+LAVK
Sbjct: 246 SQDWLAVK 253



>XP_005252833
          Length = 483

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SMDFLAVK 8
           S D+LAVK
Sbjct: 246 SQDWLAVK 253



>XP_006718197
          Length = 537

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SMDFLAVK 8
           S D+LAVK
Sbjct: 246 SQDWLAVK 253



>XP_006718196
          Length = 542

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SMDFLAVK 8
           S D+LAVK
Sbjct: 246 SQDWLAVK 253



>XP_006718195
          Length = 542

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SMDFLAVK 8
           S D+LAVK
Sbjct: 246 SQDWLAVK 253



>XP_005252832
          Length = 542

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SMDFLAVK 8
           S D+LAVK
Sbjct: 246 SQDWLAVK 253



>XP_005246888
          Length = 22663

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     DFLAVKR 9
             D+LA+KR
Sbjct: 21341 DYLAMKR 21347



>XP_006712788
          Length = 24022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     DFLAVKR 9
             D+LA+KR
Sbjct: 22700 DYLAMKR 22706



>XP_006712787
          Length = 33978

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     DFLAVKR 9
             D+LA+KR
Sbjct: 32656 DYLAMKR 32662



>XP_006712786
          Length = 35484

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     DFLAVKR 9
             D+LA+KR
Sbjct: 34162 DYLAMKR 34168



>NP_001254479
          Length = 35991

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     DFLAVKR 9
             D+LA+KR
Sbjct: 34669 DYLAMKR 34675



>NP_597681
          Length = 27118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3     DFLAVKR 9
             D+LA+KR
Sbjct: 25796 DYLAMKR 25802



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.336    0.139    0.366 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 385,375
Number of extensions: 636
Number of successful extensions: 33
Number of sequences better than 10000.0: 33
Number of HSP's gapped: 33
Number of HSP's successfully gapped: 33
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)