Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001136098                                                           20     509
NP_000360                                                              20     509
NP_001018046                                                           20     509
XP_005268096                                                           20     509
XP_006720308                                                           20     509
XP_005268094                                                           20     509
XP_005273758                                                           17    3301
XP_006718820                                                           17    3301
NP_005458                                                              17    3301
NP_443171                                                              16    5631
NP_689914                                                              16    5631
NP_079330                                                              16    5631
NP_443125                                                              16    5631
NP_001165889                                                           16    5631
XP_005276254                                                           16    5631
XP_006726434                                                           16    5631
XP_006726433                                                           16    5631
XP_006726432                                                           16    5631
XP_006726431                                                           16    5631
XP_006726411                                                           16    5631
XP_005273759                                                           16    5631
XP_005248898                                                           16    5631
XP_005277553                                                           16    5631
XP_006711781                                                           16    5631
XP_006711780                                                           16    5631
XP_006711779                                                           16    5631
XP_006711778                                                           16    5631
XP_006711209                                                           16    5631
XP_006711208                                                           16    5631
XP_006711165                                                           16    5631
NP_001092742                                                           16    5631
NP_689946                                                              16    5631
NP_848537                                                              16    7355
NP_113659                                                              16    7355
NP_071442                                                              16    7355
XP_006718767                                                           16    7355
XP_006718766                                                           16    7355
NP_004178                                                              15    9605
NP_001269551                                                           15    9605
NP_001140177                                                           15    9605
NP_056163                                                              15    9605
NP_835235                                                              15    9605
NP_775885                                                              15    9605
NP_004644                                                              15    9605
NP_001004060                                                           15    9605
NP_001004067                                                           15    9605
XP_006726609                                                           15    9605
XP_006725258                                                           15    9605
XP_005262620                                                           15    9605
XP_005262619                                                           15    9605
XP_005262618                                                           15    9605
XP_005262617                                                           15    9605
XP_006724672                                                           15    9605
XP_005262092                                                           15    9605
XP_005255375                                                           15    9605
XP_006719787                                                           15    9605
XP_005263969                                                           15    9605
XP_005263968                                                           15    9605
XP_005263967                                                           15    9605
XP_005263966                                                           15    9605
XP_006710027                                                           15    9605
NP_055102                                                              15    9605
>NP_001136098
          Length = 274

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SLYNLSKVT 9
           S YNLSKVT
Sbjct: 96  SFYNLSKVT 104
>NP_000360
          Length = 764

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SLYNLSKVT 9
           S YNLSKVT
Sbjct: 96  SFYNLSKVT 104
>NP_001018046
          Length = 253

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SLYNLSKVT 9
           S YNLSKVT
Sbjct: 96  SFYNLSKVT 104
>XP_005268096
          Length = 253

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SLYNLSKVT 9
           S YNLSKVT
Sbjct: 96  SFYNLSKVT 104
>XP_006720308
          Length = 274

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SLYNLSKVT 9
           S YNLSKVT
Sbjct: 96  SFYNLSKVT 104
>XP_005268094
          Length = 764

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SLYNLSKVT 9
           S YNLSKVT
Sbjct: 96  SFYNLSKVT 104
>XP_005273758
          Length = 686

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SLYNLSK 7
           S+YNLSK
Sbjct: 546 SIYNLSK 552

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   LYNLSKVT 9
           +YN++K+T
Sbjct: 282 VYNINKIT 289
>XP_006718820
          Length = 707

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SLYNLSK 7
           S+YNLSK
Sbjct: 567 SIYNLSK 573

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   LYNLSKVT 9
           +YN++K+T
Sbjct: 303 VYNINKIT 310
>NP_005458
          Length = 740

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SLYNLSK 7
           S+YNLSK
Sbjct: 600 SIYNLSK 606

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   LYNLSKVT 9
           +YN++K+T
Sbjct: 336 VYNINKIT 343
>NP_443171
          Length = 734

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   YNLSKVT 9
           YNL K+T
Sbjct: 144 YNLEKIT 150
>NP_689914
          Length = 5058

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    LYNLSK 7
            LYNLSK
Sbjct: 4720 LYNLSK 4725
>NP_079330
          Length = 1222

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LYNLSKVT 9
           LYNL+K T
Sbjct: 491 LYNLAKST 498
>NP_443125
          Length = 612

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SLYNLSKVT 9
           SLY+L K+T
Sbjct: 150 SLYSLPKLT 158
>NP_001165889
          Length = 582

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SLYNLSKVT 9
          SLY+L K+T
Sbjct: 91 SLYSLPKLT 99
>XP_005276254
          Length = 308

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LYNLSKVT 9
          ++N+SKVT
Sbjct: 82 MHNMSKVT 89
>XP_006726434
          Length = 146

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LYNLSKVT 9
          ++N+SKVT
Sbjct: 48 MHNMSKVT 55
>XP_006726433
          Length = 164

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LYNLSKVT 9
          ++N+SKVT
Sbjct: 82 MHNMSKVT 89
>XP_006726432
          Length = 180

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LYNLSKVT 9
          ++N+SKVT
Sbjct: 82 MHNMSKVT 89
>XP_006726431
          Length = 196

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LYNLSKVT 9
          ++N+SKVT
Sbjct: 82 MHNMSKVT 89
>XP_006726411
          Length = 274

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LYNLSKVT 9
          ++N+SKVT
Sbjct: 82 MHNMSKVT 89
>XP_005273759
          Length = 451

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   LYNLSKVT 9
           +YN++K+T
Sbjct: 336 VYNINKIT 343
>XP_005248898
          Length = 612

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SLYNLSKVT 9
           SLY+L K+T
Sbjct: 150 SLYSLPKLT 158
>XP_005277553
          Length = 308

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LYNLSKVT 9
          ++N+SKVT
Sbjct: 82 MHNMSKVT 89
>XP_006711781
          Length = 146

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LYNLSKVT 9
          ++N+SKVT
Sbjct: 48 MHNMSKVT 55
>XP_006711780
          Length = 164

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LYNLSKVT 9
          ++N+SKVT
Sbjct: 82 MHNMSKVT 89
>XP_006711779
          Length = 180

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LYNLSKVT 9
          ++N+SKVT
Sbjct: 82 MHNMSKVT 89
>XP_006711778
          Length = 196

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LYNLSKVT 9
          ++N+SKVT
Sbjct: 82 MHNMSKVT 89
>XP_006711209
          Length = 613

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   YNLSKVT 9
           YNL K+T
Sbjct: 144 YNLEKIT 150
>XP_006711208
          Length = 734

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   YNLSKVT 9
           YNL K+T
Sbjct: 144 YNLEKIT 150
>XP_006711165
          Length = 274

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LYNLSKVT 9
          ++N+SKVT
Sbjct: 82 MHNMSKVT 89
>NP_001092742
          Length = 612

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SLYNLSKVT 9
           SLY+L K+T
Sbjct: 150 SLYSLPKLT 158
>NP_689946
          Length = 544

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SLYNLSKVT 9
          SLY+L K+T
Sbjct: 82 SLYSLPKLT 90
>NP_848537
          Length = 667

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LYNLSKV 8
           LY+LSKV
Sbjct: 161 LYDLSKV 167
>NP_113659
          Length = 663

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LYNLSKV 8
           LY+LSKV
Sbjct: 161 LYDLSKV 167
>NP_071442
          Length = 690

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SLYNLSKVT 9
           +LY L K+T
Sbjct: 346 TLYELEKIT 354
>XP_006718767
          Length = 616

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LYNLSKV 8
           LY+LSKV
Sbjct: 114 LYDLSKV 120
>XP_006718766
          Length = 663

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LYNLSKV 8
           LY+LSKV
Sbjct: 161 LYDLSKV 167
>NP_004178
          Length = 1560

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LYNLSKV 8
           LY+LSK+
Sbjct: 112 LYSLSKI 118
>NP_001269551
          Length = 1559

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LYNLSKV 8
           LY+LSK+
Sbjct: 112 LYSLSKI 118
>NP_001140177
          Length = 1570

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LYNLSKV 8
           LY+LSK+
Sbjct: 112 LYSLSKI 118
>NP_056163
          Length = 1883

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SLYNLSKV 8
           S +NLSKV
Sbjct: 883 SRFNLSKV 890
>NP_835235
          Length = 505

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   SLYNLSKVT 9
           +++NLSK++
Sbjct: 214 AVFNLSKIS 222
>NP_775885
          Length = 1222

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   LYNLSK 7
           +YNLSK
Sbjct: 616 IYNLSK 621
>NP_004644
          Length = 1539

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LYNLSKV 8
           LY+LSK+
Sbjct: 112 LYSLSKI 118
>NP_001004060
          Length = 1267

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   LYNLSK 7
           +YNLSK
Sbjct: 616 IYNLSK 621
>NP_001004067
          Length = 1222

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   LYNLSK 7
           +YNLSK
Sbjct: 616 IYNLSK 621
>XP_006726609
          Length = 2838

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SLYNLSKV 8
            S YNL+K+
Sbjct: 2317 SFYNLTKL 2324
>XP_006725258
          Length = 1267

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   LYNLSK 7
           +YNLSK
Sbjct: 616 IYNLSK 621
>XP_005262620
          Length = 785

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LYNLSKV 8
           LY+LSK+
Sbjct: 112 LYSLSKI 118
>XP_005262619
          Length = 888

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LYNLSKV 8
           LY+LSK+
Sbjct: 112 LYSLSKI 118
>XP_005262618
          Length = 1462

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LYNLSKV 8
           LY+LSK+
Sbjct: 112 LYSLSKI 118
>XP_005262617
          Length = 1494

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LYNLSKV 8
           LY+LSK+
Sbjct: 112 LYSLSKI 118
>XP_006724672
          Length = 1446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LYNLSKV 8
           LY+LSK+
Sbjct: 112 LYSLSKI 118
>XP_005262092
          Length = 1557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LYNLSKV 8
           LY+LSK+
Sbjct: 112 LYSLSKI 118
>XP_005255375
          Length = 1267

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   LYNLSK 7
           +YNLSK
Sbjct: 616 IYNLSK 621
>XP_006719787
          Length = 2838

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SLYNLSKV 8
            S YNL+K+
Sbjct: 2317 SFYNLTKL 2324
>XP_005263969
          Length = 1844

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SLYNLSKV 8
           S +NLSKV
Sbjct: 844 SRFNLSKV 851
>XP_005263968
          Length = 1861

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SLYNLSKV 8
           S +NLSKV
Sbjct: 861 SRFNLSKV 868
>XP_005263967
          Length = 1899

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SLYNLSKV 8
           S +NLSKV
Sbjct: 900 SRFNLSKV 907
>XP_005263966
          Length = 1900

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SLYNLSKV 8
           S +NLSKV
Sbjct: 900 SRFNLSKV 907
>XP_006710027
          Length = 2837

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    SLYNLSKV 8
            S YNL+K+
Sbjct: 2316 SFYNLTKL 2323
>NP_055102
          Length = 1222

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   LYNLSK 7
           +YNLSK
Sbjct: 616 IYNLSK 621
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.307    0.120    0.296 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 457,708
Number of extensions: 588
Number of successful extensions: 65
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 65
Number of HSP's successfully gapped: 65
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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