Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           20     390
NP_001185763                                                           20     390
NP_055459                                                              20     390
XP_006726410                                                           20     390
XP_006711719                                                           20     390
XP_006711718                                                           20     390
XP_006711717                                                           20     390
XP_006711716                                                           20     390
XP_006711715                                                           20     390
XP_006711714                                                           20     390
XP_006711713                                                           20     390
XP_006711712                                                           20     390
XP_006711711                                                           20     390
XP_006711710                                                           20     390
XP_006711709                                                           20     390
XP_005277503                                                           20     390
XP_005273038                                                           20     390
XP_006711708                                                           20     390
XP_005277500                                                           20     390
XP_006711707                                                           20     390
XP_005277499                                                           20     390
XP_006711706                                                           20     390
XP_006711705                                                           20     390
XP_006711164                                                           20     390
XP_005276153                                                           20     390
XP_003846805                                                           20     390
NP_057218                                                              18    1935
XP_006716561                                                           18    1935
XP_005250812                                                           18    1935
NP_000833                                                              17    3301
NP_001137303                                                           17    3301
XP_006726598                                                           17    3301
XP_006718893                                                           17    3301
XP_006718892                                                           17    3301
XP_006718891                                                           17    3301
NP_001264994                                                           17    4312
NP_001264995                                                           17    4312
NP_001264996                                                           17    4312
NP_001264993                                                           17    4312
NP_060158                                                              17    4312
XP_006719941                                                           17    4312
XP_006719940                                                           17    4312
XP_005252120                                                           17    4312
XP_006717212                                                           17    4312
XP_006715531                                                           17    4312
XP_006715530                                                           17    4312
NP_113619                                                              17    4312
NP_997716                                                              16    5631
NP_001091102                                                           16    5631
XP_006717115                                                           16    5631
NP_001091105                                                           16    5631
NP_001481                                                              16    5631
NP_001091103                                                           16    5631
NP_001091104                                                           16    5631
NP_001165694                                                           16    7355
NP_443731                                                              16    7355
NP_001243064                                                           16    7355
NP_001307                                                              16    7355
NP_001012267                                                           15    9605
NP_060016                                                              15    9605
NP_063941                                                              15    9605
NP_001273898                                                           15    9605
NP_001269122                                                           15    9605
NP_001269121                                                           15    9605
NP_004600                                                              15    9605
NP_892121                                                              15    9605
NP_919412                                                              15    9605
NP_056311                                                              15    9605
NP_001273900                                                           15    9605
NP_002928                                                              15    9605
>NP_001185761
          Length = 2240

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SLVRSVCSF 9
            SLVRS CSF
Sbjct: 2100 SLVRSACSF 2108
>NP_001185763
          Length = 2362

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SLVRSVCSF 9
            SLVRS CSF
Sbjct: 2206 SLVRSACSF 2214
>NP_055459
          Length = 2346

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SLVRSVCSF 9
            SLVRS CSF
Sbjct: 2206 SLVRSACSF 2214
>XP_006726410
          Length = 2087

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SLVRSVCSF 9
            SLVRS CSF
Sbjct: 1947 SLVRSACSF 1955
>XP_006711719
          Length = 2302

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SLVRSVCSF 9
            SLVRS CSF
Sbjct: 2162 SLVRSACSF 2170
>XP_006711718
          Length = 1436

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SLVRSVCSF 9
            SLVRS CSF
Sbjct: 1213 SLVRSACSF 1221
>XP_006711717
          Length = 2385

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SLVRSVCSF 9
            SLVRS CSF
Sbjct: 2162 SLVRSACSF 2170
>XP_006711716
          Length = 2411

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SLVRSVCSF 9
            SLVRS CSF
Sbjct: 2271 SLVRSACSF 2279
>XP_006711715
          Length = 2428

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SLVRSVCSF 9
            SLVRS CSF
Sbjct: 2205 SLVRSACSF 2213
>XP_006711714
          Length = 2429

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SLVRSVCSF 9
            SLVRS CSF
Sbjct: 2206 SLVRSACSF 2214
>XP_006711713
          Length = 2432

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SLVRSVCSF 9
            SLVRS CSF
Sbjct: 2209 SLVRSACSF 2217
>XP_006711712
          Length = 2473

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SLVRSVCSF 9
            SLVRS CSF
Sbjct: 2250 SLVRSACSF 2258
>XP_006711711
          Length = 2482

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SLVRSVCSF 9
            SLVRS CSF
Sbjct: 2259 SLVRSACSF 2267
>XP_006711710
          Length = 2494

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SLVRSVCSF 9
            SLVRS CSF
Sbjct: 2271 SLVRSACSF 2279
>XP_006711709
          Length = 2495

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SLVRSVCSF 9
            SLVRS CSF
Sbjct: 2272 SLVRSACSF 2280
>XP_005277503
          Length = 2498

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SLVRSVCSF 9
            SLVRS CSF
Sbjct: 2369 SLVRSACSF 2377
>XP_005273038
          Length = 2509

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SLVRSVCSF 9
            SLVRS CSF
Sbjct: 2369 SLVRSACSF 2377
>XP_006711708
          Length = 2512

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SLVRSVCSF 9
            SLVRS CSF
Sbjct: 2289 SLVRSACSF 2297
>XP_005277500
          Length = 2525

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SLVRSVCSF 9
            SLVRS CSF
Sbjct: 2369 SLVRSACSF 2377
>XP_006711707
          Length = 2553

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SLVRSVCSF 9
            SLVRS CSF
Sbjct: 2330 SLVRSACSF 2338
>XP_005277499
          Length = 2561

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SLVRSVCSF 9
            SLVRS CSF
Sbjct: 2369 SLVRSACSF 2377
>XP_006711706
          Length = 2591

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SLVRSVCSF 9
            SLVRS CSF
Sbjct: 2368 SLVRSACSF 2376
>XP_006711705
          Length = 2592

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SLVRSVCSF 9
            SLVRS CSF
Sbjct: 2369 SLVRSACSF 2377
>XP_006711164
          Length = 2087

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SLVRSVCSF 9
            SLVRS CSF
Sbjct: 1947 SLVRSACSF 1955
>XP_005276153
          Length = 267

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SLVRSVCSF 9
           SLVRS CSF
Sbjct: 163 SLVRSACSF 171
>XP_003846805
          Length = 306

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SLVRSVCSF 9
           SLVRS CSF
Sbjct: 202 SLVRSACSF 210
>NP_057218
          Length = 472

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SLVRSVCSF 9
           SL+RSV SF
Sbjct: 202 SLIRSVASF 210
>XP_006716561
          Length = 304

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SLVRSVCSF 9
           SL+RSV SF
Sbjct: 202 SLIRSVASF 210
>XP_005250812
          Length = 472

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SLVRSVCSF 9
           SL+RSV SF
Sbjct: 202 SLIRSVASF 210
>NP_000833
          Length = 1180

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SLVRSVCS 8
           +++RSVCS
Sbjct: 505 NIIRSVCS 512
>NP_001137303
          Length = 1212

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SLVRSVCS 8
           +++RSVCS
Sbjct: 505 NIIRSVCS 512
>XP_006726598
          Length = 885

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LVRSVCSF 9
           L+R +CSF
Sbjct: 668 LIRGLCSF 675
>XP_006718893
          Length = 1180

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SLVRSVCS 8
           +++RSVCS
Sbjct: 505 NIIRSVCS 512
>XP_006718892
          Length = 1212

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SLVRSVCS 8
           +++RSVCS
Sbjct: 505 NIIRSVCS 512
>XP_006718891
          Length = 1212

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SLVRSVCS 8
           +++RSVCS
Sbjct: 505 NIIRSVCS 512
>NP_001264994
          Length = 906

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LVRSVCS 8
           +VRSVCS
Sbjct: 519 VVRSVCS 525
>NP_001264995
          Length = 906

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LVRSVCS 8
           +VRSVCS
Sbjct: 519 VVRSVCS 525
>NP_001264996
          Length = 908

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LVRSVCS 8
           +VRSVCS
Sbjct: 519 VVRSVCS 525
>NP_001264993
          Length = 1194

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LVRSVCS 8
           +VRSVCS
Sbjct: 519 VVRSVCS 525
>NP_060158
          Length = 402

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SLVRSVC 7
           SLVRS+C
Sbjct: 115 SLVRSLC 121
>XP_006719941
          Length = 699

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SLVRSVCSF 9
           +LVRS C+F
Sbjct: 235 ALVRSGCAF 243
>XP_006719940
          Length = 820

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SLVRSVCSF 9
           +LVRS C+F
Sbjct: 364 ALVRSGCAF 372
>XP_005252120
          Length = 193

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SLVRSVC 7
           SLVRS+C
Sbjct: 115 SLVRSLC 121
>XP_006717212
          Length = 401

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SLVRSVC 7
           SLVRS+C
Sbjct: 115 SLVRSLC 121
>XP_006715531
          Length = 1029

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LVRSVCS 8
           +VRSVCS
Sbjct: 519 VVRSVCS 525
>XP_006715530
          Length = 906

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LVRSVCS 8
           +VRSVCS
Sbjct: 519 VVRSVCS 525
>NP_113619
          Length = 828

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SLVRSVCSF 9
           +LVRS C+F
Sbjct: 364 ALVRSGCAF 372
>NP_997716
          Length = 227

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SLVRSVCS 8
          SLV+S CS
Sbjct: 26 SLVQSACS 33
>NP_001091102
          Length = 428

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   VRSVCSF 9
           VRSVC F
Sbjct: 377 VRSVCIF 383
>XP_006717115
          Length = 428

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   VRSVCSF 9
           VRSVC F
Sbjct: 377 VRSVCIF 383
>NP_001091105
          Length = 428

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   VRSVCSF 9
           VRSVC F
Sbjct: 377 VRSVCIF 383
>NP_001481
          Length = 428

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   VRSVCSF 9
           VRSVC F
Sbjct: 377 VRSVCIF 383
>NP_001091103
          Length = 428

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   VRSVCSF 9
           VRSVC F
Sbjct: 377 VRSVCIF 383
>NP_001091104
          Length = 428

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   VRSVCSF 9
           VRSVC F
Sbjct: 377 VRSVCIF 383
>NP_001165694
          Length = 268

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   SLVRSVC 7
           SLVR +C
Sbjct: 173 SLVRKIC 179
>NP_443731
          Length = 237

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   SLVRSVC 7
           SLVR +C
Sbjct: 142 SLVRKIC 148
>NP_001243064
          Length = 915

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   LVRSVCSF 9
           LVR +C F
Sbjct: 333 LVRGLCKF 340
>NP_001307
          Length = 971

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   LVRSVCSF 9
           LVR +C F
Sbjct: 389 LVRGLCKF 396
>NP_001012267
          Length = 288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   SLVRSVCS 8
           SL++S+C+
Sbjct: 277 SLIKSLCA 284
>NP_060016
          Length = 510

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LVRSVCSF 9
           LVR VC F
Sbjct: 448 LVRLVCVF 455
>NP_063941
          Length = 323

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SLVRSVCS 8
           SLV S+C+
Sbjct: 127 SLVASICN 134
>NP_001273898
          Length = 176

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   SLVRSVCS 8
           SL++S+C+
Sbjct: 165 SLIKSLCA 172
>NP_001269122
          Length = 147

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 3  VRSVCS 8
          +RS+CS
Sbjct: 81 IRSICS 86
>NP_001269121
          Length = 147

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 3  VRSVCS 8
          +RS+CS
Sbjct: 81 IRSICS 86
>NP_004600
          Length = 199

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   RSVCSF 9
           RS+C+F
Sbjct: 162 RSICTF 167
>NP_892121
          Length = 1147

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   LVRSVCSF 9
           L+R++C F
Sbjct: 731 LIRALCHF 738
>NP_919412
          Length = 147

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 3  VRSVCS 8
          +RS+CS
Sbjct: 81 IRSICS 86
>NP_056311
          Length = 1812

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   LVRSVCSF 9
           L+R++C F
Sbjct: 731 LIRALCHF 738
>NP_001273900
          Length = 115

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   SLVRSVCS 8
           SL++S+C+
Sbjct: 104 SLIKSLCA 111
>NP_002928
          Length = 147

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 3  VRSVCS 8
          +RS+CS
Sbjct: 81 IRSICS 86
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.337    0.134    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 527,980
Number of extensions: 544
Number of successful extensions: 70
Number of sequences better than 10000.0: 70
Number of HSP's gapped: 70
Number of HSP's successfully gapped: 70
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.5 bits)
S2: 28 (15.4 bits)

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