Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_002967                                                              16    5631
XP_006712745                                                           16    5631
XP_006712744                                                           16    5631
XP_006712743                                                           16    5631
NP_002181                                                              16    7355
NP_054722                                                              16    7355
NP_003578                                                              16    7355
NP_112170                                                              16    7355
NP_001139693                                                           16    7355
NP_001157711                                                           16    7355
XP_006726516                                                           16    7355
XP_005256326                                                           16    7355
XP_006719087                                                           16    7355
NP_001005328                                                           16    7355
NP_060139                                                              15    9605
NP_997294                                                              15    9605
NP_001276902                                                           15    9605
>NP_002967
          Length = 1682

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    SLVNIILLL 9
            +L+NIILL+
Sbjct: 1379 ALLNIILLI 1387
>XP_006712745
          Length = 1682

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    SLVNIILLL 9
            +L+NIILL+
Sbjct: 1379 ALLNIILLI 1387
>XP_006712744
          Length = 1682

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    SLVNIILLL 9
            +L+NIILL+
Sbjct: 1379 ALLNIILLI 1387
>XP_006712743
          Length = 1682

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    SLVNIILLL 9
            +L+NIILL+
Sbjct: 1379 ALLNIILLI 1387
>NP_002181
          Length = 155

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  SLVNIILLL 9
          SLV+++LLL
Sbjct: 7  SLVSLLLLL 15
>NP_054722
          Length = 1227

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SLVNIILLL 9
           +L N++LLL
Sbjct: 890 NLANVVLLL 898
>NP_003578
          Length = 1041

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SLVNIILLL 9
           SL N++LLL
Sbjct: 759 SLGNVVLLL 767
>NP_112170
          Length = 310

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SLVNIILLL 9
           SL++++LLL
Sbjct: 155 SLIHLVLLL 163
>NP_001139693
          Length = 340

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  VNIILLL 9
          VN+ILLL
Sbjct: 8  VNVILLL 14
>NP_001157711
          Length = 981

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SLVNIILLL 9
           SL N++LLL
Sbjct: 699 SLGNVVLLL 707
>XP_006726516
          Length = 310

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SLVNIILLL 9
           SL++++LLL
Sbjct: 155 SLIHLVLLL 163
>XP_005256326
          Length = 1192

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SLVNIILLL 9
           +L N++LLL
Sbjct: 855 NLANVVLLL 863
>XP_006719087
          Length = 295

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  VNIILLL 9
          VN+ILLL
Sbjct: 8  VNVILLL 14
>NP_001005328
          Length = 310

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SLVNIILLL 9
           SL++++LLL
Sbjct: 155 SLIHLVLLL 163
>NP_060139
          Length = 1250

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SLVNIILLL 9
           SLVN +LL+
Sbjct: 143 SLVNHVLLI 151
>NP_997294
          Length = 686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LVNIILLL 9
           L NIILLL
Sbjct: 273 LENIILLL 280
>NP_001276902
          Length = 523

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LVNIILLL 9
           L NIILLL
Sbjct: 110 LENIILLL 117
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.340    0.162    0.381 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 335,936
Number of extensions: 318
Number of successful extensions: 17
Number of sequences better than 10000.0: 17
Number of HSP's gapped: 17
Number of HSP's successfully gapped: 17
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)

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