Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001245202                                                           18    1482
NP_001245200                                                           18    1482
NP_001161091                                                           18    1482
NP_000240                                                              18    1482
NP_001161090                                                           18    1482
NP_001161089                                                           18    1482
NP_001245203                                                           18    1482
XP_005265221                                                           18    1482
XP_005265220                                                           18    1482
NP_000476                                                              16    5631
NP_000283                                                              16    7355
NP_057250                                                              16    7355
NP_438170                                                              16    7355
NP_001273429                                                           16    7355
NP_001018170                                                           16    7355
NP_001018169                                                           16    7355
NP_003896                                                              16    7355
NP_077015                                                              16    7355
XP_006724561                                                           16    7355
XP_005274607                                                           16    7355
XP_005274605                                                           16    7355
XP_006724560                                                           16    7355
XP_006724559                                                           16    7355
XP_005256272                                                           16    7355
XP_005254792                                                           16    7355
XP_005254791                                                           16    7355
NP_001244899                                                           16    7355
NP_061959                                                              15    9605
XP_006719530                                                           15    9605
>NP_001245202
          Length = 515

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LVESTSLR 9
          LVESTSLR
Sbjct: 25 LVESTSLR 32
>NP_001245200
          Length = 687

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LVESTSLR 9
           LVESTSLR
Sbjct: 266 LVESTSLR 273
>NP_001161091
          Length = 515

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LVESTSLR 9
          LVESTSLR
Sbjct: 25 LVESTSLR 32
>NP_000240
          Length = 756

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LVESTSLR 9
           LVESTSLR
Sbjct: 266 LVESTSLR 273
>NP_001161090
          Length = 515

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LVESTSLR 9
          LVESTSLR
Sbjct: 25 LVESTSLR 32
>NP_001161089
          Length = 658

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LVESTSLR 9
           LVESTSLR
Sbjct: 168 LVESTSLR 175
>NP_001245203
          Length = 515

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LVESTSLR 9
          LVESTSLR
Sbjct: 25 LVESTSLR 32
>XP_005265221
          Length = 515

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LVESTSLR 9
          LVESTSLR
Sbjct: 25 LVESTSLR 32
>XP_005265220
          Length = 515

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LVESTSLR 9
          LVESTSLR
Sbjct: 25 LVESTSLR 32
>NP_000476
          Length = 180

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SLVESTSLR 9
           SLVE TSL+
Sbjct: 155 SLVELTSLK 163
>NP_000283
          Length = 1235

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LVESTSLR 9
           L++STSLR
Sbjct: 667 LLQSTSLR 674
>NP_057250
          Length = 651

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SLVESTSLR 9
           SLV S SLR
Sbjct: 614 SLVSSNSLR 622
>NP_438170
          Length = 434

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SLVESTSLR 9
           SLVE  SLR
Sbjct: 141 SLVEKDSLR 149
>NP_001273429
          Length = 537

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LVESTSLR 9
           L ESTSLR
Sbjct: 134 LPESTSLR 141
>NP_001018170
          Length = 445

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  LVESTSLR 9
          L ESTSLR
Sbjct: 42 LPESTSLR 49
>NP_001018169
          Length = 528

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LVESTSLR 9
           L ESTSLR
Sbjct: 125 LPESTSLR 132
>NP_003896
          Length = 534

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   LVESTSLR 9
           L ESTSLR
Sbjct: 131 LPESTSLR 138
>NP_077015
          Length = 1004

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SLVESTSLR 9
           SLVE  SLR
Sbjct: 378 SLVEKDSLR 386
>XP_006724561
          Length = 1061

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LVESTSLR 9
           L++STSLR
Sbjct: 485 LLQSTSLR 492
>XP_005274607
          Length = 1207

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LVESTSLR 9
           L++STSLR
Sbjct: 667 LLQSTSLR 674
>XP_005274605
          Length = 1217

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LVESTSLR 9
           L++STSLR
Sbjct: 667 LLQSTSLR 674
>XP_006724560
          Length = 1225

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LVESTSLR 9
           L++STSLR
Sbjct: 667 LLQSTSLR 674
>XP_006724559
          Length = 1243

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LVESTSLR 9
           L++STSLR
Sbjct: 667 LLQSTSLR 674
>XP_005256272
          Length = 445

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  LVESTSLR 9
          L ESTSLR
Sbjct: 42 LPESTSLR 49
>XP_005254792
          Length = 642

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SLVESTSLR 9
           SLV S SLR
Sbjct: 605 SLVSSNSLR 613
>XP_005254791
          Length = 644

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SLVESTSLR 9
           SLV S SLR
Sbjct: 607 SLVSSNSLR 615
>NP_001244899
          Length = 740

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SLVESTSLR 9
           SLVE  SLR
Sbjct: 378 SLVEKDSLR 386
>NP_061959
          Length = 540

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  SLVESTSL 8
          SLV++TSL
Sbjct: 81 SLVDATSL 88
>XP_006719530
          Length = 439

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  SLVESTSL 8
          SLV++TSL
Sbjct: 81 SLVDATSL 88
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.300    0.112    0.241 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 238,586
Number of extensions: 243
Number of successful extensions: 29
Number of sequences better than 10000.0: 29
Number of HSP's gapped: 29
Number of HSP's successfully gapped: 29
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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