Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              16    5631
NP_671714                                                              16    5631
XP_006715890                                                           16    5631
XP_005250160                                                           16    5631
XP_005250159                                                           16    5631
NP_940931                                                              16    7355
XP_006721943                                                           16    7355
XP_006721942                                                           16    7355
NP_001185951                                                           15    9605
NP_055526                                                              15    9605
NP_001166246                                                           15    9605
NP_690004                                                              15    9605
NP_056372                                                              15    9605
XP_006721168                                                           15    9605
XP_005255778                                                           15    9605
XP_005255776                                                           15    9605
XP_005268211                                                           15    9605
NP_001092872                                                           15    9605
>NP_005742
          Length = 3907

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SLQKMMKRA 9
            +LQK +KRA
Sbjct: 3661 TLQKSLKRA 3669
>NP_671714
          Length = 3899

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SLQKMMKRA 9
            +LQK +KRA
Sbjct: 3653 TLQKSLKRA 3661
>XP_006715890
          Length = 3860

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SLQKMMKRA 9
            +LQK +KRA
Sbjct: 3614 TLQKSLKRA 3622
>XP_005250160
          Length = 3939

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SLQKMMKRA 9
            +LQK +KRA
Sbjct: 3693 TLQKSLKRA 3701
>XP_005250159
          Length = 3952

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SLQKMMKRA 9
            +LQK +KRA
Sbjct: 3706 TLQKSLKRA 3714
>NP_940931
          Length = 1503

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    LQKMMK 7
            LQKMMK
Sbjct: 1284 LQKMMK 1289
>XP_006721943
          Length = 1456

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    LQKMMK 7
            LQKMMK
Sbjct: 1284 LQKMMK 1289
>XP_006721942
          Length = 1503

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    LQKMMK 7
            LQKMMK
Sbjct: 1284 LQKMMK 1289
>NP_001185951
          Length = 1012

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SLQKMMKRA 9
           SLQ +MK++
Sbjct: 227 SLQNLMKKS 235
>NP_055526
          Length = 991

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SLQKMMKRA 9
           SLQ +MK++
Sbjct: 227 SLQNLMKKS 235
>NP_001166246
          Length = 627

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SLQKMMKR 8
           SLQK M+R
Sbjct: 493 SLQKHMRR 500
>NP_690004
          Length = 628

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SLQKMMKR 8
           SLQK M+R
Sbjct: 494 SLQKHMRR 501
>NP_056372
          Length = 1954

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    LQKMMKR 8
            LQKM+K+
Sbjct: 1029 LQKMLKK 1035
>XP_006721168
          Length = 971

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SLQKMMKRA 9
           SLQ +MK++
Sbjct: 227 SLQNLMKKS 235
>XP_005255778
          Length = 991

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SLQKMMKRA 9
           SLQ +MK++
Sbjct: 227 SLQNLMKKS 235
>XP_005255776
          Length = 1012

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SLQKMMKRA 9
           SLQ +MK++
Sbjct: 227 SLQNLMKKS 235
>XP_005268211
          Length = 580

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SLQKMMK 7
           SLQ MMK
Sbjct: 446 SLQSMMK 452
>NP_001092872
          Length = 580

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   SLQKMMK 7
           SLQ MMK
Sbjct: 446 SLQSMMK 452
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.324    0.118    0.274 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 338,919
Number of extensions: 575
Number of successful extensions: 18
Number of sequences better than 10000.0: 18
Number of HSP's gapped: 18
Number of HSP's successfully gapped: 18
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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