Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              20     390
NP_001075109                                                           20     390
NP_004483                                                              18    1482
XP_005254381                                                           18    1482
XP_005254382                                                           18    1482
NP_003791                                                              17    4312
NP_056020                                                              17    4312
NP_001273357                                                           17    4312
NP_001273355                                                           17    4312
NP_115565                                                              17    4312
XP_006720028                                                           17    4312
XP_005268363                                                           17    4312
XP_005268362                                                           17    4312
XP_005268358                                                           17    4312
XP_005268360                                                           17    4312
XP_005268357                                                           17    4312
XP_005268356                                                           17    4312
XP_006715652                                                           17    4312
NP_001131032                                                           17    4312
NP_003551                                                              16    5631
NP_056040                                                              16    5631
XP_006724395                                                           16    5631
XP_005261823                                                           16    5631
XP_005261822                                                           16    5631
XP_005261821                                                           16    5631
XP_005251811                                                           16    5631
XP_005251810                                                           16    5631
XP_005251809                                                           16    5631
XP_005251808                                                           16    5631
XP_005251807                                                           16    5631
XP_005251805                                                           16    5631
XP_005251803                                                           16    5631
XP_006717050                                                           16    5631
XP_005251802                                                           16    5631
XP_006717049                                                           16    5631
XP_006717048                                                           16    5631
XP_006717047                                                           16    5631
XP_006717046                                                           16    5631
XP_006717045                                                           16    5631
NP_001157413                                                           16    7355
NP_680477                                                              16    7355
NP_001254481                                                           16    7355
NP_848654                                                              16    7355
NP_001186623                                                           16    7355
NP_001186622                                                           16    7355
NP_001186621                                                           16    7355
NP_003031                                                              16    7355
NP_001842                                                              15    9605
NP_000771                                                              15    9605
NP_004906                                                              15    9605
NP_997511                                                              15    9605
NP_058198                                                              15    9605
NP_997512                                                              15    9605
NP_997510                                                              15    9605
NP_997057                                                              15    9605
NP_115667                                                              15    9605
XP_005271327                                                           15    9605
XP_005271326                                                           15    9605
XP_006711037                                                           15    9605
XP_005271325                                                           15    9605
XP_006711036                                                           15    9605
XP_006711035                                                           15    9605
XP_006711034                                                           15    9605
XP_005271323                                                           15    9605
XP_006711032                                                           15    9605
XP_006711031                                                           15    9605
XP_006711030                                                           15    9605
XP_006711029                                                           15    9605
XP_005271322                                                           15    9605
XP_006711028                                                           15    9605
XP_006711027                                                           15    9605
XP_006711026                                                           15    9605
XP_005271321                                                           15    9605
XP_006711025                                                           15    9605
XP_006711024                                                           15    9605
NP_597812                                                              15    9605
NP_113669                                                              15    9605
>NP_008835
          Length = 4128

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  SLNNIEFRE 9
          SLN+IEFRE
Sbjct: 72 SLNSIEFRE 80
>NP_001075109
          Length = 4097

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  SLNNIEFRE 9
          SLN+IEFRE
Sbjct: 72 SLNSIEFRE 80
>NP_004483
          Length = 109

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  LNNIEFRE 9
          LN++EFRE
Sbjct: 76 LNDVEFRE 83
>XP_005254381
          Length = 109

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  LNNIEFRE 9
          LN++EFRE
Sbjct: 76 LNDVEFRE 83
>XP_005254382
          Length = 109

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  LNNIEFRE 9
          LN++EFRE
Sbjct: 76 LNDVEFRE 83
>NP_003791
          Length = 597

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SLNNIEFR 8
           SLN+++FR
Sbjct: 463 SLNSVDFR 470
>NP_056020
          Length = 1134

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   NNIEFRE 9
           NN+EF+E
Sbjct: 422 NNMEFKE 428
>NP_001273357
          Length = 514

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SLNNIEFR 8
           SLN+++FR
Sbjct: 380 SLNSVDFR 387
>NP_001273355
          Length = 574

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SLNNIEFR 8
           SLN+++FR
Sbjct: 440 SLNSVDFR 447
>NP_115565
          Length = 1191

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   NNIEFRE 9
           NN+EF+E
Sbjct: 422 NNMEFKE 428
>XP_006720028
          Length = 1134

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   NNIEFRE 9
           NN+EF+E
Sbjct: 422 NNMEFKE 428
>XP_005268363
          Length = 1134

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   NNIEFRE 9
           NN+EF+E
Sbjct: 422 NNMEFKE 428
>XP_005268362
          Length = 1134

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   NNIEFRE 9
           NN+EF+E
Sbjct: 422 NNMEFKE 428
>XP_005268358
          Length = 1139

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   NNIEFRE 9
           NN+EF+E
Sbjct: 422 NNMEFKE 428
>XP_005268360
          Length = 1139

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   NNIEFRE 9
           NN+EF+E
Sbjct: 422 NNMEFKE 428
>XP_005268357
          Length = 1171

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   NNIEFRE 9
           NN+EF+E
Sbjct: 422 NNMEFKE 428
>XP_005268356
          Length = 1192

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   NNIEFRE 9
           NN+EF+E
Sbjct: 422 NNMEFKE 428
>XP_006715652
          Length = 574

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SLNNIEFR 8
           SLN+++FR
Sbjct: 440 SLNSVDFR 447
>NP_001131032
          Length = 566

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LNNIEFRE 9
           L N++FRE
Sbjct: 275 LKNVDFRE 282
>NP_003551
          Length = 806

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SLNNIEFRE 9
           SLNN+E ++
Sbjct: 445 SLNNLELQD 453
>NP_056040
          Length = 3088

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   NIEFRE 9
           N+EFRE
Sbjct: 137 NVEFRE 142
>XP_006724395
          Length = 806

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SLNNIEFRE 9
           SLNN+E ++
Sbjct: 445 SLNNLELQD 453
>XP_005261823
          Length = 806

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SLNNIEFRE 9
           SLNN+E ++
Sbjct: 445 SLNNLELQD 453
>XP_005261822
          Length = 806

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SLNNIEFRE 9
           SLNN+E ++
Sbjct: 445 SLNNLELQD 453
>XP_005261821
          Length = 806

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SLNNIEFRE 9
           SLNN+E ++
Sbjct: 445 SLNNLELQD 453
>XP_005251811
          Length = 3060

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   NIEFRE 9
           N+EFRE
Sbjct: 137 NVEFRE 142
>XP_005251810
          Length = 3062

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   NIEFRE 9
           N+EFRE
Sbjct: 137 NVEFRE 142
>XP_005251809
          Length = 3063

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   NIEFRE 9
           N+EFRE
Sbjct: 137 NVEFRE 142
>XP_005251808
          Length = 3075

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   NIEFRE 9
           N+EFRE
Sbjct: 137 NVEFRE 142
>XP_005251807
          Length = 3088

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   NIEFRE 9
           N+EFRE
Sbjct: 137 NVEFRE 142
>XP_005251805
          Length = 3090

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   NIEFRE 9
           N+EFRE
Sbjct: 137 NVEFRE 142
>XP_005251803
          Length = 3091

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   NIEFRE 9
           N+EFRE
Sbjct: 137 NVEFRE 142
>XP_006717050
          Length = 3092

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   NIEFRE 9
           N+EFRE
Sbjct: 137 NVEFRE 142
>XP_005251802
          Length = 3092

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   NIEFRE 9
           N+EFRE
Sbjct: 137 NVEFRE 142
>XP_006717049
          Length = 3100

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   NIEFRE 9
           N+EFRE
Sbjct: 137 NVEFRE 142
>XP_006717048
          Length = 3101

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   NIEFRE 9
           N+EFRE
Sbjct: 137 NVEFRE 142
>XP_006717047
          Length = 3101

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   NIEFRE 9
           N+EFRE
Sbjct: 137 NVEFRE 142
>XP_006717046
          Length = 3103

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   NIEFRE 9
           N+EFRE
Sbjct: 137 NVEFRE 142
>XP_006717045
          Length = 3104

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   NIEFRE 9
           N+EFRE
Sbjct: 137 NVEFRE 142
>NP_001157413
          Length = 1257

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    NIEFRE 9
            N+EFRE
Sbjct: 1014 NLEFRE 1019
>NP_680477
          Length = 236

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  LNNIEFRE 9
          L NI+FR+
Sbjct: 25 LGNIDFRQ 32
>NP_001254481
          Length = 232

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  LNNIEFRE 9
          L NI+FR+
Sbjct: 25 LGNIDFRQ 32
>NP_848654
          Length = 812

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   NIEFRE 9
           N+EFRE
Sbjct: 569 NLEFRE 574
>NP_001186623
          Length = 1227

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SLNNIEFRE 9
            SLN I+F E
Sbjct: 1115 SLNGIQFYE 1123
>NP_001186622
          Length = 1232

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SLNNIEFRE 9
            SLN I+F E
Sbjct: 1120 SLNGIQFYE 1128
>NP_001186621
          Length = 1241

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SLNNIEFRE 9
            SLN I+F E
Sbjct: 1129 SLNGIQFYE 1137
>NP_003031
          Length = 1241

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SLNNIEFRE 9
            SLN I+F E
Sbjct: 1129 SLNGIQFYE 1137
>NP_001842
          Length = 921

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 3  NNIEFR 8
          NN++FR
Sbjct: 91 NNVDFR 96
>NP_000771
          Length = 504

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LNNIEFR 8
           LN+IEF+
Sbjct: 492 LNDIEFK 498
>NP_004906
          Length = 678

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  NIEFRE 9
          NIEFR+
Sbjct: 76 NIEFRD 81
>NP_997511
          Length = 644

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  NIEFRE 9
          NIEFR+
Sbjct: 54 NIEFRD 59
>NP_058198
          Length = 666

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  NIEFRE 9
          NIEFR+
Sbjct: 76 NIEFRD 81
>NP_997512
          Length = 663

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  NIEFRE 9
          NIEFR+
Sbjct: 73 NIEFRD 78
>NP_997510
          Length = 668

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  NIEFRE 9
          NIEFR+
Sbjct: 78 NIEFRD 83
>NP_997057
          Length = 677

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  NIEFRE 9
          NIEFR+
Sbjct: 87 NIEFRD 92
>NP_115667
          Length = 828

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   SLNNIEF 7
           +LNN++F
Sbjct: 719 ALNNVQF 725
>XP_005271327
          Length = 629

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   SLNNIEF 7
           +LNN++F
Sbjct: 520 ALNNVQF 526
>XP_005271326
          Length = 631

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   SLNNIEF 7
           +LNN++F
Sbjct: 522 ALNNVQF 528
>XP_006711037
          Length = 631

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   SLNNIEF 7
           +LNN++F
Sbjct: 522 ALNNVQF 528
>XP_005271325
          Length = 637

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   SLNNIEF 7
           +LNN++F
Sbjct: 528 ALNNVQF 534
>XP_006711036
          Length = 659

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   SLNNIEF 7
           +LNN++F
Sbjct: 550 ALNNVQF 556
>XP_006711035
          Length = 665

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   SLNNIEF 7
           +LNN++F
Sbjct: 556 ALNNVQF 562
>XP_006711034
          Length = 667

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   SLNNIEF 7
           +LNN++F
Sbjct: 558 ALNNVQF 564
>XP_005271323
          Length = 798

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   SLNNIEF 7
           +LNN++F
Sbjct: 689 ALNNVQF 695
>XP_006711032
          Length = 804

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   SLNNIEF 7
           +LNN++F
Sbjct: 695 ALNNVQF 701
>XP_006711031
          Length = 806

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   SLNNIEF 7
           +LNN++F
Sbjct: 697 ALNNVQF 703
>XP_006711030
          Length = 808

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   SLNNIEF 7
           +LNN++F
Sbjct: 699 ALNNVQF 705
>XP_006711029
          Length = 812

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   SLNNIEF 7
           +LNN++F
Sbjct: 703 ALNNVQF 709
>XP_005271322
          Length = 822

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   SLNNIEF 7
           +LNN++F
Sbjct: 713 ALNNVQF 719
>XP_006711028
          Length = 826

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   SLNNIEF 7
           +LNN++F
Sbjct: 717 ALNNVQF 723
>XP_006711027
          Length = 830

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   SLNNIEF 7
           +LNN++F
Sbjct: 721 ALNNVQF 727
>XP_006711026
          Length = 830

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   SLNNIEF 7
           +LNN++F
Sbjct: 721 ALNNVQF 727
>XP_005271321
          Length = 832

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   SLNNIEF 7
           +LNN++F
Sbjct: 723 ALNNVQF 729
>XP_006711025
          Length = 834

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   SLNNIEF 7
           +LNN++F
Sbjct: 725 ALNNVQF 731
>XP_006711024
          Length = 834

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   SLNNIEF 7
           +LNN++F
Sbjct: 725 ALNNVQF 731
>NP_597812
          Length = 1121

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLNNIEFRE 9
           SLN I+F E
Sbjct: 967 SLNGIQFWE 975
>NP_113669
          Length = 315

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SLNNIEFRE 9
           +LNN+ F E
Sbjct: 206 NLNNLGFNE 214
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.313    0.133    0.344 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 440,206
Number of extensions: 770
Number of successful extensions: 77
Number of sequences better than 10000.0: 77
Number of HSP's gapped: 77
Number of HSP's successfully gapped: 77
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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