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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              19     869
NP_001075109                                                           19     869
NP_003706                                                              17    3301
NP_001276978                                                           17    3301
XP_006714460                                                           17    3301
XP_006714459                                                           17    3301
NP_057197                                                              17    4312
XP_006721606                                                           17    4312
XP_006721605                                                           17    4312
XP_006721604                                                           17    4312
XP_005256733                                                           17    4312
NP_061849                                                              16    5631
NP_037524                                                              16    5631
XP_005269040                                                           16    5631
XP_005264331                                                           16    5631
NP_000250                                                              16    7355
NP_001135967                                                           16    7355
XP_005254459                                                           16    7355
XP_005254458                                                           16    7355
XP_005254457                                                           16    7355
XP_005254456                                                           16    7355
XP_005254455                                                           16    7355
XP_005254454                                                           16    7355
NP_001073936                                                           15    9605
NP_001248755                                                           15    9605
NP_003929                                                              15    9605
XP_006722995                                                           15    9605

>NP_008835
          Length = 4128

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SLLSETINT 9
            SL SETINT
Sbjct: 1561 SLFSETINT 1569



>NP_001075109
          Length = 4097

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    SLLSETINT 9
            SL SETINT
Sbjct: 1561 SLFSETINT 1569



>NP_003706
          Length = 962

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LLSETINT 9
           +L+ETINT
Sbjct: 329 ILTETINT 336



>NP_001276978
          Length = 973

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LLSETINT 9
           +L+ETINT
Sbjct: 333 ILTETINT 340



>XP_006714460
          Length = 966

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LLSETINT 9
           +L+ETINT
Sbjct: 333 ILTETINT 340



>XP_006714459
          Length = 969

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LLSETINT 9
           +L+ETINT
Sbjct: 329 ILTETINT 336



>NP_057197
          Length = 764

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SLLSETINT 9
           +L+SET+N+
Sbjct: 643 ALMSETVNS 651



>XP_006721606
          Length = 680

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SLLSETINT 9
           +L+SET+N+
Sbjct: 643 ALMSETVNS 651



>XP_006721605
          Length = 680

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SLLSETINT 9
           +L+SET+N+
Sbjct: 643 ALMSETVNS 651



>XP_006721604
          Length = 733

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SLLSETINT 9
           +L+SET+N+
Sbjct: 643 ALMSETVNS 651



>XP_005256733
          Length = 763

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SLLSETINT 9
           +L+SET+N+
Sbjct: 642 ALMSETVNS 650



>NP_061849
          Length = 506

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LLSETINT 9
           +++ETINT
Sbjct: 252 IINETINT 259



>NP_037524
          Length = 535

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SLLSETIN 8
           SLL ET+N
Sbjct: 509 SLLEETLN 516



>XP_005269040
          Length = 406

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LLSETINT 9
           +++ETINT
Sbjct: 152 IINETINT 159



>XP_005264331
          Length = 535

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   SLLSETIN 8
           SLL ET+N
Sbjct: 509 SLLEETLN 516



>NP_000250
          Length = 1855

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SLLSETINT 9
            SLL+ TIN+
Sbjct: 1531 SLLTSTINS 1539



>NP_001135967
          Length = 1828

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SLLSETINT 9
            SLL+ TIN+
Sbjct: 1504 SLLTSTINS 1512



>XP_005254459
          Length = 1825

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SLLSETINT 9
            SLL+ TIN+
Sbjct: 1501 SLLTSTINS 1509



>XP_005254458
          Length = 1852

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SLLSETINT 9
            SLL+ TIN+
Sbjct: 1528 SLLTSTINS 1536



>XP_005254457
          Length = 1853

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SLLSETINT 9
            SLL+ TIN+
Sbjct: 1529 SLLTSTINS 1537



>XP_005254456
          Length = 1877

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SLLSETINT 9
            SLL+ TIN+
Sbjct: 1553 SLLTSTINS 1561



>XP_005254455
          Length = 1880

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SLLSETINT 9
            SLL+ TIN+
Sbjct: 1556 SLLTSTINS 1564



>XP_005254454
          Length = 1880

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SLLSETINT 9
            SLL+ TIN+
Sbjct: 1556 SLLTSTINS 1564



>NP_001073936
          Length = 1848

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    SLLSETIN 8
            SLL+ TIN
Sbjct: 1523 SLLTSTIN 1530



>NP_001248755
          Length = 1215

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLLSETINT 9
           SLL E +NT
Sbjct: 274 SLLYECVNT 282



>NP_003929
          Length = 1153

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLLSETINT 9
           SLL E +NT
Sbjct: 274 SLLYECVNT 282



>XP_006722995
          Length = 1203

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLLSETINT 9
           SLL E +NT
Sbjct: 274 SLLYECVNT 282



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.296    0.113    0.254 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 294,749
Number of extensions: 266
Number of successful extensions: 27
Number of sequences better than 10000.0: 27
Number of HSP's gapped: 27
Number of HSP's successfully gapped: 27
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.1 bits)
S2: 28 (15.4 bits)