Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000360                                                              18    1135
XP_005268094                                                           18    1135
NP_115582                                                              16    7355
XP_006721363                                                           16    7355
XP_005256258                                                           16    7355
XP_005256257                                                           16    7355
XP_005256256                                                           16    7355
XP_005256255                                                           16    7355
XP_006721362                                                           16    7355
XP_006721361                                                           16    7355
XP_005256254                                                           16    7355
XP_005256253                                                           16    7355
XP_005256252                                                           16    7355
XP_005256251                                                           16    7355
XP_006721360                                                           16    7355
XP_005256250                                                           16    7355
NP_037363                                                              15    9605
NP_938205                                                              15    9605
NP_037413                                                              15    9605
XP_005260739                                                           15    9605
XP_006720158                                                           15    9605
XP_005267547                                                           15    9605
XP_005267546                                                           15    9605
>NP_000360
          Length = 764

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   SLLEVSQTS 9
           SLL+VSQTS
Sbjct: 229 SLLDVSQTS 237
>XP_005268094
          Length = 764

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   SLLEVSQTS 9
           SLL+VSQTS
Sbjct: 229 SLLDVSQTS 237
>NP_115582
          Length = 1866

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    SLLEVSQT 8
            SLL++SQT
Sbjct: 1166 SLLQLSQT 1173
>XP_006721363
          Length = 1385

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    SLLEVSQT 8
            SLL++SQT
Sbjct: 1166 SLLQLSQT 1173
>XP_005256258
          Length = 1397

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    SLLEVSQT 8
            SLL++SQT
Sbjct: 1136 SLLQLSQT 1143
>XP_005256257
          Length = 1405

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    SLLEVSQT 8
            SLL++SQT
Sbjct: 1166 SLLQLSQT 1173
>XP_005256256
          Length = 1427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    SLLEVSQT 8
            SLL++SQT
Sbjct: 1166 SLLQLSQT 1173
>XP_005256255
          Length = 1809

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    SLLEVSQT 8
            SLL++SQT
Sbjct: 1166 SLLQLSQT 1173
>XP_006721362
          Length = 1810

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    SLLEVSQT 8
            SLL++SQT
Sbjct: 1166 SLLQLSQT 1173
>XP_006721361
          Length = 1836

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    SLLEVSQT 8
            SLL++SQT
Sbjct: 1136 SLLQLSQT 1143
>XP_005256254
          Length = 1837

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    SLLEVSQT 8
            SLL++SQT
Sbjct: 1166 SLLQLSQT 1173
>XP_005256253
          Length = 1838

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    SLLEVSQT 8
            SLL++SQT
Sbjct: 1138 SLLQLSQT 1145
>XP_005256252
          Length = 1865

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    SLLEVSQT 8
            SLL++SQT
Sbjct: 1166 SLLQLSQT 1173
>XP_005256251
          Length = 1866

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    SLLEVSQT 8
            SLL++SQT
Sbjct: 1166 SLLQLSQT 1173
>XP_006721360
          Length = 1866

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    SLLEVSQT 8
            SLL++SQT
Sbjct: 1166 SLLQLSQT 1173
>XP_005256250
          Length = 1866

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    SLLEVSQT 8
            SLL++SQT
Sbjct: 1166 SLLQLSQT 1173
>NP_037363
          Length = 660

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SLLEVSQTS 9
           S+LE+++TS
Sbjct: 598 SILEMTETS 606
>NP_938205
          Length = 649

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SLLEVSQTS 9
           S+LE+ +TS
Sbjct: 585 SILEIRETS 593
>NP_037413
          Length = 649

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SLLEVSQTS 9
           S+LE+ +TS
Sbjct: 585 SILEIRETS 593
>XP_005260739
          Length = 649

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SLLEVSQTS 9
           S+LE+ +TS
Sbjct: 585 SILEIRETS 593
>XP_006720158
          Length = 660

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SLLEVSQTS 9
           S+LE+++TS
Sbjct: 598 SILEMTETS 606
>XP_005267547
          Length = 660

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SLLEVSQTS 9
           S+LE+++TS
Sbjct: 598 SILEMTETS 606
>XP_005267546
          Length = 660

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SLLEVSQTS 9
           S+LE+++TS
Sbjct: 598 SILEMTETS 606
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.289    0.104    0.216 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 286,676
Number of extensions: 322
Number of successful extensions: 23
Number of sequences better than 10000.0: 23
Number of HSP's gapped: 23
Number of HSP's successfully gapped: 23
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.0 bits)
S2: 28 (15.4 bits)

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