Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006197                                                              19     869
XP_006714104                                                           19     869
XP_005265800                                                           19     869
XP_006714103                                                           19     869
XP_006714102                                                           19     869
NP_001177894                                                           17    4312
NP_001177893                                                           17    4312
NP_932072                                                              17    4312
NP_003444                                                              17    4312
XP_005266578                                                           17    4312
XP_005266576                                                           17    4312
XP_005266575                                                           17    4312
XP_005266577                                                           17    4312
XP_005266574                                                           17    4312
NP_001002880                                                           16    5631
NP_056188                                                              16    5631
NP_055521                                                              16    7355
NP_055895                                                              16    7355
NP_620060                                                              16    7355
XP_005269298                                                           16    7355
XP_006718812                                                           16    7355
XP_005274463                                                           16    7355
XP_006718811                                                           16    7355
XP_006718810                                                           16    7355
XP_006718809                                                           16    7355
XP_006718808                                                           16    7355
XP_006718807                                                           16    7355
XP_006718806                                                           16    7355
XP_006718805                                                           16    7355
XP_005274459                                                           16    7355
XP_005274458                                                           16    7355
XP_005274457                                                           16    7355
NP_001155048                                                           15    9605
NP_056404                                                              15    9605
NP_001110                                                              15    9605
NP_054909                                                              15    9605
NP_001158213                                                           15    9605
NP_054908                                                              15    9605
NP_789771                                                              15    9605
NP_001657                                                              15    9605
NP_997698                                                              15    9605
NP_001073986                                                           15    9605
NP_001597                                                              15    9605
XP_005268297                                                           15    9605
XP_006717059                                                           15    9605
XP_006716762                                                           15    9605
XP_005251165                                                           15    9605
XP_005251164                                                           15    9605
XP_005251163                                                           15    9605
XP_006716755                                                           15    9605
XP_005265364                                                           15    9605
XP_006713308                                                           15    9605
XP_006713307                                                           15    9605
XP_006713306                                                           15    9605
XP_005265360                                                           15    9605
XP_006713305                                                           15    9605
XP_005265358                                                           15    9605
XP_006713304                                                           15    9605
XP_006713303                                                           15    9605
XP_005265356                                                           15    9605
XP_006713302                                                           15    9605
XP_006713301                                                           15    9605
XP_006713300                                                           15    9605
XP_006713299                                                           15    9605
XP_006713298                                                           15    9605
NP_001098                                                              15    9605
>NP_006197
          Length = 1089

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SLDRSTVEG 9
           S DRSTVEG
Sbjct: 478 SRDRSTVEG 486
>XP_006714104
          Length = 832

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SLDRSTVEG 9
           S DRSTVEG
Sbjct: 503 SRDRSTVEG 511
>XP_005265800
          Length = 1089

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SLDRSTVEG 9
           S DRSTVEG
Sbjct: 478 SRDRSTVEG 486
>XP_006714103
          Length = 1111

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SLDRSTVEG 9
           S DRSTVEG
Sbjct: 500 SRDRSTVEG 508
>XP_006714102
          Length = 1114

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SLDRSTVEG 9
           S DRSTVEG
Sbjct: 503 SRDRSTVEG 511
>NP_001177894
          Length = 1377

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    SLDRSTVE 8
            SLDR+T+E
Sbjct: 1345 SLDRNTLE 1352
>NP_001177893
          Length = 1377

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    SLDRSTVE 8
            SLDR+T+E
Sbjct: 1345 SLDRNTLE 1352
>NP_932072
          Length = 1377

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    SLDRSTVE 8
            SLDR+T+E
Sbjct: 1345 SLDRNTLE 1352
>NP_003444
          Length = 1377

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    SLDRSTVE 8
            SLDR+T+E
Sbjct: 1345 SLDRNTLE 1352
>XP_005266578
          Length = 1290

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    SLDRSTVE 8
            SLDR+T+E
Sbjct: 1258 SLDRNTLE 1265
>XP_005266576
          Length = 1377

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    SLDRSTVE 8
            SLDR+T+E
Sbjct: 1345 SLDRNTLE 1352
>XP_005266575
          Length = 1377

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    SLDRSTVE 8
            SLDR+T+E
Sbjct: 1345 SLDRNTLE 1352
>XP_005266577
          Length = 1377

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    SLDRSTVE 8
            SLDR+T+E
Sbjct: 1345 SLDRNTLE 1352
>XP_005266574
          Length = 1377

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    SLDRSTVE 8
            SLDR+T+E
Sbjct: 1345 SLDRNTLE 1352
>NP_001002880
          Length = 169

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  SLDRSTVE 8
          SLDRST E
Sbjct: 69 SLDRSTRE 76
>NP_056188
          Length = 126

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  SLDRSTVE 8
          SLDRST E
Sbjct: 26 SLDRSTRE 33
>NP_055521
          Length = 963

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LDRSTVEG 9
           +DR +VEG
Sbjct: 765 MDRKSVEG 772
>NP_055895
          Length = 1712

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLDRSTVEG 9
           S+D  TVEG
Sbjct: 838 SVDNVTVEG 846
>NP_620060
          Length = 1642

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLDRSTVEG 9
           S+D  TVEG
Sbjct: 798 SVDNVTVEG 806
>XP_005269298
          Length = 981

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LDRSTVEG 9
           +DR +VEG
Sbjct: 783 MDRKSVEG 790
>XP_006718812
          Length = 1226

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLDRSTVEG 9
           S+D  TVEG
Sbjct: 576 SVDNVTVEG 584
>XP_005274463
          Length = 974

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLDRSTVEG 9
           S+D  TVEG
Sbjct: 100 SVDNVTVEG 108
>XP_006718811
          Length = 1420

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLDRSTVEG 9
           S+D  TVEG
Sbjct: 576 SVDNVTVEG 584
>XP_006718810
          Length = 1450

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLDRSTVEG 9
           S+D  TVEG
Sbjct: 576 SVDNVTVEG 584
>XP_006718809
          Length = 1450

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLDRSTVEG 9
           S+D  TVEG
Sbjct: 576 SVDNVTVEG 584
>XP_006718808
          Length = 1454

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLDRSTVEG 9
           S+D  TVEG
Sbjct: 610 SVDNVTVEG 618
>XP_006718807
          Length = 1464

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLDRSTVEG 9
           S+D  TVEG
Sbjct: 590 SVDNVTVEG 598
>XP_006718806
          Length = 1474

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLDRSTVEG 9
           S+D  TVEG
Sbjct: 600 SVDNVTVEG 608
>XP_006718805
          Length = 1484

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLDRSTVEG 9
           S+D  TVEG
Sbjct: 610 SVDNVTVEG 618
>XP_005274459
          Length = 1503

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLDRSTVEG 9
           S+D  TVEG
Sbjct: 823 SVDNVTVEG 831
>XP_005274458
          Length = 1511

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLDRSTVEG 9
           S+D  TVEG
Sbjct: 831 SVDNVTVEG 839
>XP_005274457
          Length = 1705

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SLDRSTVEG 9
           S+D  TVEG
Sbjct: 831 SVDNVTVEG 839
>NP_001155048
          Length = 630

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SLDRSTVEG 9
           SL+R  +EG
Sbjct: 301 SLERDIIEG 309
>NP_056404
          Length = 718

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SLDRSTVEG 9
           SL+R  +EG
Sbjct: 389 SLERDIIEG 397
>NP_001110
          Length = 737

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LDRSTVEG 9
           +DRS V+G
Sbjct: 529 MDRSLVQG 536
>NP_054909
          Length = 631

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LDRSTVEG 9
           +DRS V+G
Sbjct: 529 MDRSLVQG 536
>NP_001158213
          Length = 986

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   LDRSTVE 8
           LDR T+E
Sbjct: 409 LDRQTIE 415
>NP_054908
          Length = 768

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LDRSTVEG 9
           +DRS V+G
Sbjct: 560 MDRSLVQG 567
>NP_789771
          Length = 662

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LDRSTVEG 9
           +DRS V+G
Sbjct: 560 MDRSLVQG 567
>NP_001657
          Length = 946

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   LDRSTVE 8
           LDR T+E
Sbjct: 369 LDRQTIE 375
>NP_997698
          Length = 2466

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LDRSTV 7
           LDRSTV
Sbjct: 172 LDRSTV 177
>NP_001073986
          Length = 1442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SLDRSTVEG 9
           +LD +T EG
Sbjct: 197 NLDENTTEG 205
>NP_001597
          Length = 2436

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LDRSTV 7
           LDRSTV
Sbjct: 142 LDRSTV 147
>XP_005268297
          Length = 129

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  DRSTVEG 9
          DR TV+G
Sbjct: 74 DRGTVQG 80
>XP_006717059
          Length = 2435

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LDRSTV 7
           LDRSTV
Sbjct: 141 LDRSTV 146
>XP_006716762
          Length = 1571

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    SLDRSTVE 8
            +LDRST++
Sbjct: 1158 TLDRSTMD 1165
>XP_005251165
          Length = 1532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    SLDRSTVE 8
            +LDRST++
Sbjct: 1119 TLDRSTMD 1126
>XP_005251164
          Length = 1552

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    SLDRSTVE 8
            +LDRST++
Sbjct: 1139 TLDRSTMD 1146
>XP_005251163
          Length = 1574

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    SLDRSTVE 8
            +LDRST++
Sbjct: 1161 TLDRSTMD 1168
>XP_006716755
          Length = 1634

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    SLDRSTVE 8
            +LDRST++
Sbjct: 1221 TLDRSTMD 1228
>XP_005265364
          Length = 1344

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SLDRSTVEG 9
           +LD +T EG
Sbjct: 99  NLDENTTEG 107
>XP_006713308
          Length = 1351

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SLDRSTVEG 9
          +LD +T EG
Sbjct: 86 NLDENTTEG 94
>XP_006713307
          Length = 1351

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SLDRSTVEG 9
          +LD +T EG
Sbjct: 86 NLDENTTEG 94
>XP_006713306
          Length = 1364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SLDRSTVEG 9
           +LD +T EG
Sbjct: 99  NLDENTTEG 107
>XP_005265360
          Length = 1442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SLDRSTVEG 9
           +LD +T EG
Sbjct: 178 NLDENTTEG 186
>XP_006713305
          Length = 1456

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SLDRSTVEG 9
           +LD +T EG
Sbjct: 191 NLDENTTEG 199
>XP_005265358
          Length = 1461

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SLDRSTVEG 9
           +LD +T EG
Sbjct: 216 NLDENTTEG 224
>XP_006713304
          Length = 1468

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SLDRSTVEG 9
           +LD +T EG
Sbjct: 223 NLDENTTEG 231
>XP_006713303
          Length = 1475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SLDRSTVEG 9
           +LD +T EG
Sbjct: 210 NLDENTTEG 218
>XP_005265356
          Length = 1481

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SLDRSTVEG 9
           +LD +T EG
Sbjct: 236 NLDENTTEG 244
>XP_006713302
          Length = 1494

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SLDRSTVEG 9
           +LD +T EG
Sbjct: 229 NLDENTTEG 237
>XP_006713301
          Length = 1494

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SLDRSTVEG 9
           +LD +T EG
Sbjct: 229 NLDENTTEG 237
>XP_006713300
          Length = 1500

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SLDRSTVEG 9
           +LD +T EG
Sbjct: 236 NLDENTTEG 244
>XP_006713299
          Length = 1501

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SLDRSTVEG 9
           +LD +T EG
Sbjct: 236 NLDENTTEG 244
>XP_006713298
          Length = 1501

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SLDRSTVEG 9
           +LD +T EG
Sbjct: 236 NLDENTTEG 244
>NP_001098
          Length = 99

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  DRSTVEG 9
          DR TV+G
Sbjct: 44 DRGTVQG 50
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.299    0.121    0.300 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 452,478
Number of extensions: 791
Number of successful extensions: 66
Number of sequences better than 10000.0: 66
Number of HSP's gapped: 66
Number of HSP's successfully gapped: 66
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.1 bits)
S2: 28 (15.4 bits)

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