Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              18    1135
XP_005262424                                                           18    1135
NP_001274433                                                           16    5631
NP_065859                                                              16    5631
NP_490595                                                              16    5631
XP_005263889                                                           16    5631
XP_006712890                                                           16    5631
XP_005263888                                                           16    5631
XP_005263887                                                           16    5631
XP_005246870                                                           16    5631
XP_005246869                                                           16    5631
XP_006711862                                                           16    5631
XP_005273271                                                           16    5631
XP_005273270                                                           16    5631
XP_005273269                                                           16    5631
XP_005273268                                                           16    5631
XP_005273266                                                           16    5631
XP_006711861                                                           16    5631
NP_001123917                                                           16    5631
NP_001274432                                                           16    5631
NP_006742                                                              16    5631
NP_005621                                                              16    7355
NP_001139784                                                           16    7355
NP_705832                                                              16    7355
XP_005256921                                                           16    7355
NP_006720                                                              15    9605
NP_065816                                                              15    9605
NP_001019554                                                           15    9605
NP_705618                                                              15    9605
NP_055718                                                              15    9605
NP_004289                                                              15    9605
NP_001265241                                                           15    9605
XP_006719740                                                           15    9605
XP_006719739                                                           15    9605
XP_006719738                                                           15    9605
XP_005269272                                                           15    9605
XP_006710573                                                           15    9605
XP_006710572                                                           15    9605
XP_006710571                                                           15    9605
XP_006710570                                                           15    9605
XP_006710569                                                           15    9605
XP_006710568                                                           15    9605
XP_006710567                                                           15    9605
XP_006710566                                                           15    9605
XP_005245859                                                           15    9605
NP_002168                                                              15    9605
>NP_722576
          Length = 3080

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SKSSGAISS 9
            SKS+GAISS
Sbjct: 1682 SKSTGAISS 1690
>XP_005262424
          Length = 2875

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    SKSSGAISS 9
            SKS+GAISS
Sbjct: 1477 SKSTGAISS 1485
>NP_001274433
          Length = 1084

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  KSSGAISS 9
          KSSG +SS
Sbjct: 8  KSSGTVSS 15
>NP_065859
          Length = 1722

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SKSSGAISS 9
            SKSSG++ S
Sbjct: 1357 SKSSGSLDS 1365
>NP_490595
          Length = 730

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SKSSGAISS 9
           SKSSG+ SS
Sbjct: 638 SKSSGSSSS 646
>XP_005263889
          Length = 555

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SKSSGAISS 9
           SKSSG+ SS
Sbjct: 463 SKSSGSSSS 471
>XP_006712890
          Length = 586

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SKSSGAISS 9
           SKSSG+ SS
Sbjct: 494 SKSSGSSSS 502
>XP_005263888
          Length = 586

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SKSSGAISS 9
           SKSSG+ SS
Sbjct: 494 SKSSGSSSS 502
>XP_005263887
          Length = 709

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SKSSGAISS 9
           SKSSG+ SS
Sbjct: 617 SKSSGSSSS 625
>XP_005246870
          Length = 1252

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KSSGAISS 9
           KSSG +SS
Sbjct: 161 KSSGTVSS 168
>XP_005246869
          Length = 1255

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KSSGAISS 9
           KSSG +SS
Sbjct: 161 KSSGTVSS 168
>XP_006711862
          Length = 1704

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SKSSGAISS 9
            SKSSG++ S
Sbjct: 1357 SKSSGSLDS 1365
>XP_005273271
          Length = 1722

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SKSSGAISS 9
            SKSSG++ S
Sbjct: 1357 SKSSGSLDS 1365
>XP_005273270
          Length = 1722

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SKSSGAISS 9
            SKSSG++ S
Sbjct: 1357 SKSSGSLDS 1365
>XP_005273269
          Length = 1722

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SKSSGAISS 9
            SKSSG++ S
Sbjct: 1357 SKSSGSLDS 1365
>XP_005273268
          Length = 1722

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SKSSGAISS 9
            SKSSG++ S
Sbjct: 1357 SKSSGSLDS 1365
>XP_005273266
          Length = 1722

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SKSSGAISS 9
            SKSSG++ S
Sbjct: 1357 SKSSGSLDS 1365
>XP_006711861
          Length = 1722

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SKSSGAISS 9
            SKSSG++ S
Sbjct: 1357 SKSSGSLDS 1365
>NP_001123917
          Length = 1259

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KSSGAISS 9
           KSSG +SS
Sbjct: 161 KSSGTVSS 168
>NP_001274432
          Length = 1237

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KSSGAISS 9
           KSSG +SS
Sbjct: 161 KSSGTVSS 168
>NP_006742
          Length = 1256

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KSSGAISS 9
           KSSG +SS
Sbjct: 161 KSSGTVSS 168
>NP_005621
          Length = 643

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  SKSSGAISS 9
          S SSG ISS
Sbjct: 67 SSSSGLISS 75
>NP_001139784
          Length = 986

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SKSSGAIS 8
           SKSS AIS
Sbjct: 756 SKSSSAIS 763
>NP_705832
          Length = 938

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SKSSGAIS 8
           SKSS AIS
Sbjct: 708 SKSSSAIS 715
>XP_005256921
          Length = 907

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SKSSGAIS 8
           SKSS AIS
Sbjct: 677 SKSSSAIS 684
>NP_006720
          Length = 1101

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SKSSGAISS 9
            S+ +GAISS
Sbjct: 1092 SRHNGAISS 1100
>NP_065816
          Length = 5183

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SKSSGAISS 9
            S S+GAIS+
Sbjct: 2934 SSSTGAIST 2942
>NP_001019554
          Length = 2385

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SKSSGAISS 9
            SKS+GA +S
Sbjct: 1168 SKSAGATTS 1176
>NP_705618
          Length = 1391

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SKSSGAISS 9
            +KSS AISS
Sbjct: 1125 AKSSTAISS 1133
>NP_055718
          Length = 2363

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SKSSGAISS 9
            SKS+GA +S
Sbjct: 1168 SKSAGATTS 1176
>NP_004289
          Length = 1332

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SKSSGAISS 9
            +KSS AISS
Sbjct: 1066 AKSSTAISS 1074
>NP_001265241
          Length = 1327

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SKSSGAISS 9
            +KSS AISS
Sbjct: 1061 AKSSTAISS 1069
>XP_006719740
          Length = 1863

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SKSSGAISS 9
           SKS+GA +S
Sbjct: 668 SKSAGATTS 676
>XP_006719739
          Length = 2306

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SKSSGAISS 9
            SKS+GA +S
Sbjct: 1111 SKSAGATTS 1119
>XP_006719738
          Length = 2340

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SKSSGAISS 9
            SKS+GA +S
Sbjct: 1145 SKSAGATTS 1153
>XP_005269272
          Length = 2356

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SKSSGAISS 9
            SKS+GA +S
Sbjct: 1168 SKSAGATTS 1176
>XP_006710573
          Length = 5177

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SKSSGAISS 9
            S S+GAIS+
Sbjct: 2928 SSSTGAIST 2936
>XP_006710572
          Length = 5188

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SKSSGAISS 9
            S S+GAIS+
Sbjct: 2939 SSSTGAIST 2947
>XP_006710571
          Length = 5194

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SKSSGAISS 9
            S S+GAIS+
Sbjct: 2945 SSSTGAIST 2953
>XP_006710570
          Length = 5195

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SKSSGAISS 9
            S S+GAIS+
Sbjct: 2946 SSSTGAIST 2954
>XP_006710569
          Length = 5212

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SKSSGAISS 9
            S S+GAIS+
Sbjct: 2963 SSSTGAIST 2971
>XP_006710568
          Length = 5221

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SKSSGAISS 9
            S S+GAIS+
Sbjct: 2972 SSSTGAIST 2980
>XP_006710567
          Length = 5222

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SKSSGAISS 9
            S S+GAIS+
Sbjct: 2973 SSSTGAIST 2981
>XP_006710566
          Length = 5222

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SKSSGAISS 9
            S S+GAIS+
Sbjct: 2973 SSSTGAIST 2981
>XP_005245859
          Length = 5223

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SKSSGAISS 9
            S S+GAIS+
Sbjct: 2974 SSSTGAIST 2982
>NP_002168
          Length = 195

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   KSSGAISS 9
           +S+GAISS
Sbjct: 131 ESAGAISS 138
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.272   0.0901    0.188 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 350,864
Number of extensions: 521
Number of successful extensions: 46
Number of sequences better than 10000.0: 46
Number of HSP's gapped: 46
Number of HSP's successfully gapped: 46
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.5 bits)
S2: 28 (15.4 bits)

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