Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_037440                                                              19     869
XP_005247460                                                           19     869
XP_005247459                                                           19     869
NP_001074924                                                           17    2528
XP_006713895                                                           17    2528
XP_005247980                                                           17    2528
XP_005247979                                                           17    2528
XP_005247978                                                           17    2528
NP_055694                                                              17    2528
NP_004358                                                              17    3301
NP_113597                                                              17    3301
NP_001245340                                                           17    3301
NP_001245342                                                           17    3301
NP_443176                                                              17    3301
NP_001245341                                                           17    3301
NP_001245343                                                           17    3301
XP_005255139                                                           17    3301
XP_006721078                                                           17    3301
XP_005255138                                                           17    3301
XP_006721077                                                           17    3301
XP_005255137                                                           17    3301
NP_775760                                                              17    4312
XP_006714502                                                           17    4312
NP_001010893                                                           16    5631
NP_001077430                                                           16    7355
NP_775907                                                              16    7355
NP_001257906                                                           16    7355
NP_001257904                                                           16    7355
NP_001257905                                                           16    7355
NP_055576                                                              16    7355
NP_665682                                                              16    7355
NP_001154806                                                           16    7355
NP_001188410                                                           16    7355
NP_115912                                                              16    7355
NP_001188411                                                           16    7355
NP_001188409                                                           16    7355
NP_056542                                                              16    7355
NP_056280                                                              16    7355
NP_005758                                                              16    7355
NP_001155969                                                           16    7355
NP_001049                                                              16    7355
NP_001239085                                                           16    7355
XP_005258866                                                           16    7355
XP_006716126                                                           16    7355
XP_005250566                                                           16    7355
XP_005250565                                                           16    7355
XP_006712295                                                           16    7355
XP_006712294                                                           16    7355
NP_001120832                                                           16    7355
NP_001120831                                                           16    7355
NP_001120829                                                           16    7355
NP_001120830                                                           16    7355
NP_065165                                                              16    7355
NP_001155970                                                           16    7355
NP_006436                                                              15    9605
NP_003741                                                              15    9605
NP_006662                                                              15    9605
NP_001274524                                                           15    9605
NP_001274526                                                           15    9605
NP_003560                                                              15    9605
NP_945314                                                              15    9605
>NP_037440
          Length = 319

 Score = 18.9 bits (37), Expect =   869
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SKIVSTVIW 9
           +K++STV+W
Sbjct: 131 AKMISTVVW 139
>XP_005247460
          Length = 319

 Score = 18.9 bits (37), Expect =   869
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SKIVSTVIW 9
           +K++STV+W
Sbjct: 131 AKMISTVVW 139
>XP_005247459
          Length = 319

 Score = 18.9 bits (37), Expect =   869
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SKIVSTVIW 9
           +K++STV+W
Sbjct: 131 AKMISTVVW 139
>NP_001074924
          Length = 338

 Score = 17.3 bits (33), Expect =  2528
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   SKIVSTVIW 9
           SK++S ++W
Sbjct: 138 SKLLSVIVW 146
>XP_006713895
          Length = 338

 Score = 17.3 bits (33), Expect =  2528
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   SKIVSTVIW 9
           SK++S ++W
Sbjct: 138 SKLLSVIVW 146
>XP_005247980
          Length = 338

 Score = 17.3 bits (33), Expect =  2528
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   SKIVSTVIW 9
           SK++S ++W
Sbjct: 138 SKLLSVIVW 146
>XP_005247979
          Length = 338

 Score = 17.3 bits (33), Expect =  2528
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   SKIVSTVIW 9
           SK++S ++W
Sbjct: 138 SKLLSVIVW 146
>XP_005247978
          Length = 338

 Score = 17.3 bits (33), Expect =  2528
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   SKIVSTVIW 9
           SK++S ++W
Sbjct: 138 SKLLSVIVW 146
>NP_055694
          Length = 338

 Score = 17.3 bits (33), Expect =  2528
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   SKIVSTVIW 9
           SK++S ++W
Sbjct: 138 SKLLSVIVW 146
>NP_004358
          Length = 374

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SKIVSTVIW 9
           SKI+  V+W
Sbjct: 164 SKIICLVVW 172
>NP_113597
          Length = 374

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SKIVSTVIW 9
           SKI+  V+W
Sbjct: 164 SKIICLVVW 172
>NP_001245340
          Length = 640

 Score = 16.9 bits (32), Expect =  3301
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   SKIVSTVIW 9
           SK+V  ++W
Sbjct: 580 SKVVKAILW 588
>NP_001245342
          Length = 611

 Score = 16.9 bits (32), Expect =  3301
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   SKIVSTVIW 9
           SK+V  ++W
Sbjct: 551 SKVVKAILW 559
>NP_443176
          Length = 675

 Score = 16.9 bits (32), Expect =  3301
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   SKIVSTVIW 9
           SK+V  ++W
Sbjct: 615 SKVVKAILW 623
>NP_001245341
          Length = 605

 Score = 16.9 bits (32), Expect =  3301
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   SKIVSTVIW 9
           SK+V  ++W
Sbjct: 545 SKVVKAILW 553
>NP_001245343
          Length = 519

 Score = 16.9 bits (32), Expect =  3301
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   SKIVSTVIW 9
           SK+V  ++W
Sbjct: 459 SKVVKAILW 467
>XP_005255139
          Length = 514

 Score = 16.9 bits (32), Expect =  3301
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   SKIVSTVIW 9
           SK+V  ++W
Sbjct: 454 SKVVKAILW 462
>XP_006721078
          Length = 576

 Score = 16.9 bits (32), Expect =  3301
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   SKIVSTVIW 9
           SK+V  ++W
Sbjct: 516 SKVVKAILW 524
>XP_005255138
          Length = 583

 Score = 16.9 bits (32), Expect =  3301
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   SKIVSTVIW 9
           SK+V  ++W
Sbjct: 523 SKVVKAILW 531
>XP_006721077
          Length = 655

 Score = 16.9 bits (32), Expect =  3301
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   SKIVSTVIW 9
           SK+V  ++W
Sbjct: 595 SKVVKAILW 603
>XP_005255137
          Length = 675

 Score = 16.9 bits (32), Expect =  3301
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   SKIVSTVIW 9
           SK+V  ++W
Sbjct: 615 SKVVKAILW 623
>NP_775760
          Length = 1585

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KIVSTVIW 9
           K +STV+W
Sbjct: 563 KNISTVLW 570
>XP_006714502
          Length = 1064

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  KIVSTVIW 9
          K +STV+W
Sbjct: 46 KNISTVLW 53
>NP_001010893
          Length = 438

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   SKIVSTVIW 9
           SKIVST+++
Sbjct: 272 SKIVSTLLF 280
>NP_001077430
          Length = 1523

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    SKIVSTVIW 9
            +++VST +W
Sbjct: 1453 TELVSTFLW 1461
>NP_775907
          Length = 1518

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    SKIVSTVIW 9
            +++VST +W
Sbjct: 1448 TELVSTFLW 1456
>NP_001257906
          Length = 335

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   VSTVIW 9
           VST+IW
Sbjct: 100 VSTLIW 105
>NP_001257904
          Length = 366

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   VSTVIW 9
           VST+IW
Sbjct: 100 VSTLIW 105
>NP_001257905
          Length = 379

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   VSTVIW 9
           VST+IW
Sbjct: 113 VSTLIW 118
>NP_055576
          Length = 360

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   VSTVIW 9
           VST+IW
Sbjct: 100 VSTLIW 105
>NP_665682
          Length = 938

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SKIVSTVIW 9
           SK+ S V+W
Sbjct: 930 SKVDSPVLW 938
>NP_001154806
          Length = 134

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/9 (33%), Positives = 7/9 (77%)

Query: 1   SKIVSTVIW 9
           SK++  ++W
Sbjct: 125 SKLIGPILW 133
>NP_001188410
          Length = 903

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SKIVSTVIW 9
           SK+ S V+W
Sbjct: 895 SKVDSPVLW 903
>NP_115912
          Length = 934

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SKIVSTVIW 9
           SK+ S V+W
Sbjct: 926 SKVDSPVLW 934
>NP_001188411
          Length = 898

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SKIVSTVIW 9
           SK+ S V+W
Sbjct: 890 SKVDSPVLW 898
>NP_001188409
          Length = 959

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SKIVSTVIW 9
           SK+ S V+W
Sbjct: 951 SKVDSPVLW 959
>NP_056542
          Length = 311

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SKIVSTVIW 9
           +K+V  VIW
Sbjct: 147 TKVVICVIW 155
>NP_056280
          Length = 1508

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   KIVSTVIW 9
           K+V+T+ W
Sbjct: 579 KLVNTISW 586
>NP_005758
          Length = 344

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SKIVSTVIW 9
           +KIV T +W
Sbjct: 133 AKIVCTGVW 141
>NP_001155969
          Length = 344

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SKIVSTVIW 9
           +KIV T +W
Sbjct: 133 AKIVCTGVW 141
>NP_001049
          Length = 407

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SKIVSTVIW 9
           +K+V  VIW
Sbjct: 147 TKVVICVIW 155
>NP_001239085
          Length = 1507

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   KIVSTVIW 9
           K+V+T+ W
Sbjct: 578 KLVNTISW 585
>XP_005258866
          Length = 1486

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    SKIVSTVIW 9
            +++VST +W
Sbjct: 1416 TELVSTFLW 1424
>XP_006716126
          Length = 708

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/9 (33%), Positives = 6/9 (66%)

Query: 1  SKIVSTVIW 9
          SK+   ++W
Sbjct: 3  SKVTDAIVW 11
>XP_005250566
          Length = 751

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/9 (33%), Positives = 6/9 (66%)

Query: 1  SKIVSTVIW 9
          SK+   ++W
Sbjct: 3  SKVTDAIVW 11
>XP_005250565
          Length = 751

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/9 (33%), Positives = 6/9 (66%)

Query: 1  SKIVSTVIW 9
          SK+   ++W
Sbjct: 3  SKVTDAIVW 11
>XP_006712295
          Length = 923

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SKIVSTVIW 9
           SK+ S V+W
Sbjct: 915 SKVDSPVLW 923
>XP_006712294
          Length = 928

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SKIVSTVIW 9
           SK+ S V+W
Sbjct: 920 SKVDSPVLW 928
>NP_001120832
          Length = 352

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/9 (33%), Positives = 6/9 (66%)

Query: 1  SKIVSTVIW 9
          SK+   ++W
Sbjct: 3  SKVTDAIVW 11
>NP_001120831
          Length = 356

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/9 (33%), Positives = 6/9 (66%)

Query: 1  SKIVSTVIW 9
          SK+   ++W
Sbjct: 3  SKVTDAIVW 11
>NP_001120829
          Length = 751

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/9 (33%), Positives = 6/9 (66%)

Query: 1  SKIVSTVIW 9
          SK+   ++W
Sbjct: 3  SKVTDAIVW 11
>NP_001120830
          Length = 747

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/9 (33%), Positives = 6/9 (66%)

Query: 1  SKIVSTVIW 9
          SK+   ++W
Sbjct: 3  SKVTDAIVW 11
>NP_065165
          Length = 747

 Score = 15.8 bits (29), Expect =  7355
 Identities = 3/9 (33%), Positives = 6/9 (66%)

Query: 1  SKIVSTVIW 9
          SK+   ++W
Sbjct: 3  SKVTDAIVW 11
>NP_001155970
          Length = 344

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SKIVSTVIW 9
           +KIV T +W
Sbjct: 133 AKIVCTGVW 141
>NP_006436
          Length = 2335

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 2    KIVSTVIW 9
            KI+ T +W
Sbjct: 1820 KIIHTSVW 1827
>NP_003741
          Length = 1382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4   VSTVIW 9
           VSTV W
Sbjct: 279 VSTVFW 284
>NP_006662
          Length = 560

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 2   KIVSTVIW 9
           KIV+  +W
Sbjct: 259 KIVAVAVW 266
>NP_001274524
          Length = 619

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 2   KIVSTVIW 9
           KIV+  +W
Sbjct: 259 KIVAVAVW 266
>NP_001274526
          Length = 472

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 2   KIVSTVIW 9
           KIV+  +W
Sbjct: 187 KIVAVAVW 194
>NP_003560
          Length = 261

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   IVSTVIW 9
           I+S +IW
Sbjct: 251 IISLIIW 257
>NP_945314
          Length = 1386

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1    SKIVSTVI 8
            S+I+ST++
Sbjct: 1373 SRIISTIV 1380
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.321    0.126    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 356,160
Number of extensions: 524
Number of successful extensions: 61
Number of sequences better than 10000.0: 61
Number of HSP's gapped: 61
Number of HSP's successfully gapped: 61
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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