Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006715                                                              19     665
NP_005913                                                              19     665
XP_005267046                                                           19     665
XP_005267045                                                           19     665
NP_055722                                                              18    1135
NP_060854                                                              18    1935
NP_001186506                                                           18    1935
XP_006717956                                                           18    1935
NP_055928                                                              17    4312
NP_055726                                                              17    4312
NP_060128                                                              17    4312
XP_005256619                                                           17    4312
XP_006721549                                                           17    4312
XP_006721548                                                           17    4312
XP_005256618                                                           17    4312
XP_005256617                                                           17    4312
XP_006720237                                                           17    4312
XP_005267827                                                           17    4312
XP_005267826                                                           17    4312
NP_055874                                                              16    5631
XP_006720784                                                           16    5631
XP_006720783                                                           16    5631
XP_006720782                                                           16    5631
XP_006720781                                                           16    5631
XP_005254772                                                           16    5631
XP_005254771                                                           16    5631
XP_006720780                                                           16    5631
XP_005254769                                                           16    5631
XP_005254770                                                           16    5631
XP_005254765                                                           16    5631
XP_005254767                                                           16    5631
XP_006720779                                                           16    5631
XP_005254768                                                           16    5631
XP_005254764                                                           16    5631
NP_002949                                                              16    7355
NP_055714                                                              16    7355
NP_001005861                                                           16    7355
NP_001268678                                                           15    9605
NP_079440                                                              15    9605
NP_001268677                                                           15    9605
NP_057427                                                              15    9605
NP_055178                                                              15    9605
NP_006292                                                              15    9605
NP_001180440                                                           15    9605
NP_001264984                                                           15    9605
NP_001171988                                                           15    9605
NP_078893                                                              15    9605
XP_005266395                                                           15    9605
XP_005269197                                                           15    9605
XP_006719652                                                           15    9605
XP_006719651                                                           15    9605
XP_005269195                                                           15    9605
XP_005271543                                                           15    9605
XP_005271542                                                           15    9605
XP_005271541                                                           15    9605
XP_005271539                                                           15    9605
XP_005271538                                                           15    9605
XP_006717349                                                           15    9605
XP_005252266                                                           15    9605
XP_005252265                                                           15    9605
XP_005252264                                                           15    9605
XP_006717348                                                           15    9605
XP_006717347                                                           15    9605
XP_006717346                                                           15    9605
>NP_006715
          Length = 1558

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SIKLLVREC 9
           SIK LVREC
Sbjct: 647 SIKQLVREC 655
>NP_005913
          Length = 1608

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SIKLLVREC 9
           SIK LVREC
Sbjct: 647 SIKQLVREC 655
>XP_005267046
          Length = 1554

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SIKLLVREC 9
           SIK LVREC
Sbjct: 647 SIKQLVREC 655
>XP_005267045
          Length = 1604

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SIKLLVREC 9
           SIK LVREC
Sbjct: 647 SIKQLVREC 655
>NP_055722
          Length = 1578

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    SIKLLVREC 9
            S+KLL R+C
Sbjct: 1550 SVKLLARQC 1558
>NP_060854
          Length = 307

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SIKLLVREC 9
           S+K LVREC
Sbjct: 172 SLKDLVREC 180
>NP_001186506
          Length = 511

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SIKLLVREC 9
           S+K LVREC
Sbjct: 376 SLKDLVREC 384
>XP_006717956
          Length = 375

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IKLLVREC 9
           +KLLV+EC
Sbjct: 139 LKLLVQEC 146
>NP_055928
          Length = 2961

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    IKLLVREC 9
            +KLLV++C
Sbjct: 2381 LKLLVKKC 2388
>NP_055726
          Length = 961

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SIKLLVREC 9
           S KLL +EC
Sbjct: 311 SFKLLKKEC 319
>NP_060128
          Length = 571

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IKLLVREC 9
           IKL+++EC
Sbjct: 117 IKLVLKEC 124
>XP_005256619
          Length = 1581

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    IKLLVREC 9
            +KLLV++C
Sbjct: 997  LKLLVKKC 1004
>XP_006721549
          Length = 1581

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    IKLLVREC 9
            +KLLV++C
Sbjct: 997  LKLLVKKC 1004
>XP_006721548
          Length = 1886

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    IKLLVREC 9
            +KLLV++C
Sbjct: 1302 LKLLVKKC 1309
>XP_005256618
          Length = 2962

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    IKLLVREC 9
            +KLLV++C
Sbjct: 2382 LKLLVKKC 2389
>XP_005256617
          Length = 2966

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    IKLLVREC 9
            +KLLV++C
Sbjct: 2382 LKLLVKKC 2389
>XP_006720237
          Length = 332

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IKLLVREC 9
           IKL+++EC
Sbjct: 131 IKLVLKEC 138
>XP_005267827
          Length = 571

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IKLLVREC 9
           IKL+++EC
Sbjct: 117 IKLVLKEC 124
>XP_005267826
          Length = 585

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   IKLLVREC 9
           IKL+++EC
Sbjct: 131 IKLVLKEC 138
>NP_055874
          Length = 2542

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SIKLLVREC 9
          S+K+ VR C
Sbjct: 5  SLKICVRHC 13
>XP_006720784
          Length = 2502

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SIKLLVREC 9
          S+K+ VR C
Sbjct: 5  SLKICVRHC 13
>XP_006720783
          Length = 2512

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SIKLLVREC 9
          S+K+ VR C
Sbjct: 5  SLKICVRHC 13
>XP_006720782
          Length = 2517

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SIKLLVREC 9
          S+K+ VR C
Sbjct: 5  SLKICVRHC 13
>XP_006720781
          Length = 2542

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SIKLLVREC 9
          S+K+ VR C
Sbjct: 5  SLKICVRHC 13
>XP_005254772
          Length = 2557

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SIKLLVREC 9
          S+K+ VR C
Sbjct: 5  SLKICVRHC 13
>XP_005254771
          Length = 2557

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SIKLLVREC 9
          S+K+ VR C
Sbjct: 5  SLKICVRHC 13
>XP_006720780
          Length = 2557

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SIKLLVREC 9
          S+K+ VR C
Sbjct: 5  SLKICVRHC 13
>XP_005254769
          Length = 2557

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SIKLLVREC 9
          S+K+ VR C
Sbjct: 5  SLKICVRHC 13
>XP_005254770
          Length = 2557

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SIKLLVREC 9
          S+K+ VR C
Sbjct: 5  SLKICVRHC 13
>XP_005254765
          Length = 2557

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SIKLLVREC 9
          S+K+ VR C
Sbjct: 5  SLKICVRHC 13
>XP_005254767
          Length = 2557

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SIKLLVREC 9
          S+K+ VR C
Sbjct: 5  SLKICVRHC 13
>XP_006720779
          Length = 2557

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SIKLLVREC 9
          S+K+ VR C
Sbjct: 5  SLKICVRHC 13
>XP_005254768
          Length = 2557

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SIKLLVREC 9
          S+K+ VR C
Sbjct: 5  SLKICVRHC 13
>XP_005254764
          Length = 2557

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  SIKLLVREC 9
          S+K+ VR C
Sbjct: 5  SLKICVRHC 13
>NP_002949
          Length = 607

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   SIKLLVREC 9
           ++KL +R+C
Sbjct: 418 NLKLFLRQC 426
>NP_055714
          Length = 611

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  SIKLLVREC 9
          ++KL+V +C
Sbjct: 65 NVKLVVHDC 73
>NP_001005861
          Length = 610

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   SIKLLVREC 9
           ++KL +R+C
Sbjct: 421 NLKLFLRQC 429
>NP_001268678
          Length = 1261

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SIKLLVREC 9
           SIK L +EC
Sbjct: 647 SIKQLQQEC 655
>NP_079440
          Length = 1321

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SIKLLVREC 9
           SIK L +EC
Sbjct: 647 SIKQLQQEC 655
>NP_001268677
          Length = 1102

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SIKLLVREC 9
           SIK L +EC
Sbjct: 488 SIKQLQQEC 496
>NP_057427
          Length = 3114

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2    IKLLVREC 9
            +KLL++ C
Sbjct: 2795 MKLLIKSC 2802
>NP_055178
          Length = 4579

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SIKLLVREC 9
            S+KLLV  C
Sbjct: 3131 SLKLLVDYC 3139
>NP_006292
          Length = 859

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   KLLVREC 9
           K+L+R+C
Sbjct: 340 KILLRQC 346
>NP_001180440
          Length = 892

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   KLLVREC 9
           K+L+R+C
Sbjct: 373 KILLRQC 379
>NP_001264984
          Length = 4432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SIKLLVREC 9
            S+KLLV  C
Sbjct: 2984 SLKLLVDYC 2992
>NP_001171988
          Length = 1495

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IKLLVREC 9
           + LLV+EC
Sbjct: 368 VLLLVQEC 375
>NP_078893
          Length = 1495

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IKLLVREC 9
           + LLV+EC
Sbjct: 368 VLLLVQEC 375
>XP_005266395
          Length = 4588

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SIKLLVREC 9
            S+KLLV  C
Sbjct: 3140 SLKLLVDYC 3148
>XP_005269197
          Length = 453

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   KLLVREC 9
           K+L+R+C
Sbjct: 373 KILLRQC 379
>XP_006719652
          Length = 759

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   KLLVREC 9
           K+L+R+C
Sbjct: 240 KILLRQC 246
>XP_006719651
          Length = 892

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   KLLVREC 9
           K+L+R+C
Sbjct: 373 KILLRQC 379
>XP_005269195
          Length = 892

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   KLLVREC 9
           K+L+R+C
Sbjct: 373 KILLRQC 379
>XP_005271543
          Length = 722

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  SIKLLVREC 9
          SIK L +EC
Sbjct: 48 SIKQLQQEC 56
>XP_005271542
          Length = 770

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SIKLLVREC 9
           SIK L +EC
Sbjct: 96  SIKQLQQEC 104
>XP_005271541
          Length = 1203

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SIKLLVREC 9
           SIK L +EC
Sbjct: 589 SIKQLQQEC 597
>XP_005271539
          Length = 1263

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SIKLLVREC 9
           SIK L +EC
Sbjct: 589 SIKQLQQEC 597
>XP_005271538
          Length = 1369

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SIKLLVREC 9
           SIK L +EC
Sbjct: 695 SIKQLQQEC 703
>XP_006717349
          Length = 1046

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IKLLVREC 9
           + LLV+EC
Sbjct: 368 VLLLVQEC 375
>XP_005252266
          Length = 1046

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IKLLVREC 9
           + LLV+EC
Sbjct: 368 VLLLVQEC 375
>XP_005252265
          Length = 1381

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IKLLVREC 9
           + LLV+EC
Sbjct: 368 VLLLVQEC 375
>XP_005252264
          Length = 1478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IKLLVREC 9
           + LLV+EC
Sbjct: 368 VLLLVQEC 375
>XP_006717348
          Length = 1541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IKLLVREC 9
           + LLV+EC
Sbjct: 368 VLLLVQEC 375
>XP_006717347
          Length = 1541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IKLLVREC 9
           + LLV+EC
Sbjct: 368 VLLLVQEC 375
>XP_006717346
          Length = 1541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   IKLLVREC 9
           + LLV+EC
Sbjct: 368 VLLLVQEC 375
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.333    0.144    0.417 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 447,279
Number of extensions: 745
Number of successful extensions: 64
Number of sequences better than 10000.0: 64
Number of HSP's gapped: 64
Number of HSP's successfully gapped: 64
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.3 bits)
S2: 28 (15.4 bits)

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