Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001255213                                                           18    1482
NP_005124                                                              18    1482
NP_079337                                                              18    1482
XP_005272554                                                           18    1482
NP_001255214                                                           18    1482
NP_942015                                                              17    3301
NP_055726                                                              17    3301
NP_055318                                                              17    4312
XP_006719406                                                           17    4312
XP_005266918                                                           17    4312
NP_001004339                                                           16    5631
NP_078922                                                              16    5631
NP_689654                                                              16    5631
XP_006710961                                                           16    5631
NP_001866                                                              16    7355
NP_001166896                                                           16    7355
NP_056219                                                              16    7355
NP_542410                                                              16    7355
NP_542411                                                              16    7355
NP_542412                                                              16    7355
NP_055664                                                              16    7355
NP_079146                                                              16    7355
NP_001116105                                                           16    7355
NP_612382                                                              16    7355
NP_001018655                                                           16    7355
NP_001277117                                                           16    7355
NP_001277118                                                           16    7355
NP_001018656                                                           16    7355
NP_001277121                                                           16    7355
NP_001277120                                                           16    7355
NP_001277123                                                           16    7355
NP_001018657                                                           16    7355
NP_001277122                                                           16    7355
NP_001277119                                                           16    7355
NP_001018654                                                           16    7355
NP_001269588                                                           16    7355
NP_060414                                                              16    7355
XP_005253054                                                           16    7355
XP_006717104                                                           16    7355
XP_005251954                                                           16    7355
XP_005251952                                                           16    7355
NP_085132                                                              15    9605
NP_938204                                                              15    9605
NP_036376                                                              15    9605
NP_001073906                                                           15    9605
NP_005867                                                              15    9605
XP_006721348                                                           15    9605
XP_005256239                                                           15    9605
XP_005256238                                                           15    9605
XP_005256236                                                           15    9605
XP_006712470                                                           15    9605
XP_006712469                                                           15    9605
XP_006712468                                                           15    9605
XP_005247054                                                           15    9605
XP_006712256                                                           15    9605
XP_005246298                                                           15    9605
XP_005246297                                                           15    9605
XP_005246299                                                           15    9605
XP_006712255                                                           15    9605
XP_005246296                                                           15    9605
XP_006712254                                                           15    9605
XP_005246295                                                           15    9605
XP_006712253                                                           15    9605
XP_006712252                                                           15    9605
XP_005246294                                                           15    9605
XP_006712251                                                           15    9605
XP_005246293                                                           15    9605
XP_005246292                                                           15    9605
XP_006712250                                                           15    9605
>NP_001255213
          Length = 796

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SGLRLLSVS 9
           SGLRLL VS
Sbjct: 676 SGLRLLDVS 684
>NP_005124
          Length = 329

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  GLRLLSVS 9
          GLRLLSVS
Sbjct: 8  GLRLLSVS 15
>NP_079337
          Length = 796

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SGLRLLSVS 9
           SGLRLL VS
Sbjct: 676 SGLRLLDVS 684
>XP_005272554
          Length = 796

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SGLRLLSVS 9
           SGLRLL VS
Sbjct: 676 SGLRLLDVS 684
>NP_001255214
          Length = 667

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SGLRLLSVS 9
           SGLRLL VS
Sbjct: 547 SGLRLLDVS 555
>NP_942015
          Length = 504

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SGLRLLSVS 9
           SGLRLL +S
Sbjct: 109 SGLRLLDLS 117
>NP_055726
          Length = 961

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SGLRLLSVS 9
           SGL LLSVS
Sbjct: 768 SGLPLLSVS 776
>NP_055318
          Length = 2785

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SGLRLLSVS 9
            SGLRLL +S
Sbjct: 2086 SGLRLLHLS 2094
>XP_006719406
          Length = 2380

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SGLRLLSVS 9
            SGLRLL +S
Sbjct: 2086 SGLRLLHLS 2094
>XP_005266918
          Length = 1298

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   GLRLLSV 8
           GLRLLSV
Sbjct: 855 GLRLLSV 861
>NP_001004339
          Length = 759

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SGLRLLSV 8
           +GLR+LSV
Sbjct: 181 TGLRILSV 188
>NP_078922
          Length = 744

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SGLRLLSVS 9
           SGLR LS++
Sbjct: 162 SGLRALSIT 170
>NP_689654
          Length = 418

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   SGLRLLSVS 9
           +GLRLL++S
Sbjct: 228 TGLRLLNLS 236
>XP_006710961
          Length = 740

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SGLRLLSVS 9
           SGLR LS++
Sbjct: 158 SGLRALSIT 166
>NP_001866
          Length = 1500

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  GLRLLSV 8
          G+RLLSV
Sbjct: 35 GIRLLSV 41
>NP_001166896
          Length = 906

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SGLRLLSVS 9
          +GLRLLS +
Sbjct: 30 AGLRLLSAN 38
>NP_056219
          Length = 907

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SGLRLLSVS 9
          +GLRLLS +
Sbjct: 30 AGLRLLSAN 38
>NP_542410
          Length = 1629

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    LRLLSVS 9
            LRLLSVS
Sbjct: 1533 LRLLSVS 1539
>NP_542411
          Length = 1736

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    LRLLSVS 9
            LRLLSVS
Sbjct: 1640 LRLLSVS 1646
>NP_542412
          Length = 1650

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    LRLLSVS 9
            LRLLSVS
Sbjct: 1554 LRLLSVS 1560
>NP_055664
          Length = 742

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   GLRLLSVS 9
           GLRL SVS
Sbjct: 518 GLRLKSVS 525
>NP_079146
          Length = 1606

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    SGLRLLSVS 9
            SG+ LLSVS
Sbjct: 1506 SGVGLLSVS 1514
>NP_001116105
          Length = 1506

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  GLRLLSV 8
          G+RLLSV
Sbjct: 41 GIRLLSV 47
>NP_612382
          Length = 322

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SGLRLLSV 8
           SGL LLSV
Sbjct: 241 SGLALLSV 248
>NP_001018655
          Length = 322

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SGLRLLSV 8
           SGL LLSV
Sbjct: 241 SGLALLSV 248
>NP_001277117
          Length = 322

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SGLRLLSV 8
           SGL LLSV
Sbjct: 241 SGLALLSV 248
>NP_001277118
          Length = 322

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SGLRLLSV 8
           SGL LLSV
Sbjct: 241 SGLALLSV 248
>NP_001018656
          Length = 322

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SGLRLLSV 8
           SGL LLSV
Sbjct: 241 SGLALLSV 248
>NP_001277121
          Length = 322

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SGLRLLSV 8
           SGL LLSV
Sbjct: 241 SGLALLSV 248
>NP_001277120
          Length = 322

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SGLRLLSV 8
           SGL LLSV
Sbjct: 241 SGLALLSV 248
>NP_001277123
          Length = 322

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SGLRLLSV 8
           SGL LLSV
Sbjct: 241 SGLALLSV 248
>NP_001018657
          Length = 322

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SGLRLLSV 8
           SGL LLSV
Sbjct: 241 SGLALLSV 248
>NP_001277122
          Length = 322

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SGLRLLSV 8
           SGL LLSV
Sbjct: 241 SGLALLSV 248
>NP_001277119
          Length = 322

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SGLRLLSV 8
           SGL LLSV
Sbjct: 241 SGLALLSV 248
>NP_001018654
          Length = 322

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   SGLRLLSV 8
           SGL LLSV
Sbjct: 241 SGLALLSV 248
>NP_001269588
          Length = 1355

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   LRLLSVS 9
           LRLLSVS
Sbjct: 751 LRLLSVS 757
>NP_060414
          Length = 1287

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   LRLLSVS 9
           LRLLSVS
Sbjct: 683 LRLLSVS 689
>XP_005253054
          Length = 1375

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   LRLLSVS 9
           LRLLSVS
Sbjct: 771 LRLLSVS 777
>XP_006717104
          Length = 574

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SGLRLLSVS 9
          +GLRLLS +
Sbjct: 30 AGLRLLSAN 38
>XP_005251954
          Length = 686

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SGLRLLSVS 9
          +GLRLLS +
Sbjct: 30 AGLRLLSAN 38
>XP_005251952
          Length = 907

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  SGLRLLSVS 9
          +GLRLLS +
Sbjct: 30 AGLRLLSAN 38
>NP_085132
          Length = 679

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SGLRLLS 7
           +GLRLLS
Sbjct: 607 AGLRLLS 613
>NP_938204
          Length = 773

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SGLRLLS 7
           +GLRLLS
Sbjct: 701 AGLRLLS 707
>NP_036376
          Length = 535

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SGLRLLS 7
           SGLRLL+
Sbjct: 159 SGLRLLA 165
>NP_001073906
          Length = 1413

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  SGLRLLSV 8
          SGLR LSV
Sbjct: 51 SGLRPLSV 58
>NP_005867
          Length = 3267

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    GLRLLSVS 9
            GLRLLS S
Sbjct: 2348 GLRLLSRS 2355
>XP_006721348
          Length = 586

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SGLRLLS 7
           +GLRLLS
Sbjct: 514 AGLRLLS 520
>XP_005256239
          Length = 586

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SGLRLLS 7
           +GLRLLS
Sbjct: 514 AGLRLLS 520
>XP_005256238
          Length = 586

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SGLRLLS 7
           +GLRLLS
Sbjct: 514 AGLRLLS 520
>XP_005256236
          Length = 737

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SGLRLLS 7
           +GLRLLS
Sbjct: 665 AGLRLLS 671
>XP_006712470
          Length = 1327

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  SGLRLLSV 8
          SGLR LSV
Sbjct: 51 SGLRPLSV 58
>XP_006712469
          Length = 1380

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  SGLRLLSV 8
          SGLR LSV
Sbjct: 51 SGLRPLSV 58
>XP_006712468
          Length = 1413

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  SGLRLLSV 8
          SGLR LSV
Sbjct: 51 SGLRPLSV 58
>XP_005247054
          Length = 1434

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  SGLRLLSV 8
          SGLR LSV
Sbjct: 51 SGLRPLSV 58
>XP_006712256
          Length = 2418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    GLRLLSVS 9
            GLRLLS S
Sbjct: 1499 GLRLLSRS 1506
>XP_005246298
          Length = 2418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    GLRLLSVS 9
            GLRLLS S
Sbjct: 1499 GLRLLSRS 1506
>XP_005246297
          Length = 2418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    GLRLLSVS 9
            GLRLLS S
Sbjct: 1499 GLRLLSRS 1506
>XP_005246299
          Length = 2480

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    GLRLLSVS 9
            GLRLLS S
Sbjct: 1561 GLRLLSRS 1568
>XP_006712255
          Length = 2622

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    GLRLLSVS 9
            GLRLLS S
Sbjct: 2348 GLRLLSRS 2355
>XP_005246296
          Length = 2475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    GLRLLSVS 9
            GLRLLS S
Sbjct: 1556 GLRLLSRS 1563
>XP_006712254
          Length = 2475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    GLRLLSVS 9
            GLRLLS S
Sbjct: 1556 GLRLLSRS 1563
>XP_005246295
          Length = 3114

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    GLRLLSVS 9
            GLRLLS S
Sbjct: 2195 GLRLLSRS 2202
>XP_006712253
          Length = 3117

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    GLRLLSVS 9
            GLRLLS S
Sbjct: 2198 GLRLLSRS 2205
>XP_006712252
          Length = 3163

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    GLRLLSVS 9
            GLRLLS S
Sbjct: 2244 GLRLLSRS 2251
>XP_005246294
          Length = 3173

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    GLRLLSVS 9
            GLRLLS S
Sbjct: 2254 GLRLLSRS 2261
>XP_006712251
          Length = 3176

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    GLRLLSVS 9
            GLRLLS S
Sbjct: 2257 GLRLLSRS 2264
>XP_005246293
          Length = 3206

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    GLRLLSVS 9
            GLRLLS S
Sbjct: 2287 GLRLLSRS 2294
>XP_005246292
          Length = 3208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    GLRLLSVS 9
            GLRLLS S
Sbjct: 2289 GLRLLSRS 2296
>XP_006712250
          Length = 3248

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    GLRLLSVS 9
            GLRLLS S
Sbjct: 2329 GLRLLSRS 2336
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.316    0.133    0.315 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 374,165
Number of extensions: 670
Number of successful extensions: 69
Number of sequences better than 10000.0: 69
Number of HSP's gapped: 69
Number of HSP's successfully gapped: 69
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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