Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001269166                                                           16    5631
NP_001269167                                                           16    5631
NP_075049                                                              16    5631
NP_612808                                                              16    5631
NP_115731                                                              16    7355
XP_006713408                                                           16    7355
NP_001139661                                                           15    9605
NP_001139662                                                           15    9605
NP_060227                                                              15    9605
XP_006722564                                                           15    9605
XP_006722563                                                           15    9605
XP_005266783                                                           15    9605
>NP_001269166
          Length = 893

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  SGLGVMV 7
          SGLG+MV
Sbjct: 41 SGLGLMV 47
>NP_001269167
          Length = 822

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  SGLGVMV 7
          SGLG+MV
Sbjct: 41 SGLGLMV 47
>NP_075049
          Length = 823

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  SGLGVMV 7
          SGLG+MV
Sbjct: 42 SGLGLMV 48
>NP_612808
          Length = 894

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  SGLGVMV 7
          SGLG+MV
Sbjct: 42 SGLGLMV 48
>NP_115731
          Length = 652

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SGLGVMVAM 9
           S +GVMVA+
Sbjct: 277 STMGVMVAL 285
>XP_006713408
          Length = 555

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SGLGVMVAM 9
           S +GVMVA+
Sbjct: 180 STMGVMVAL 188
>NP_001139661
          Length = 1815

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SGLGVMVAM 9
            SGL V +AM
Sbjct: 1427 SGLNVHIAM 1435
>NP_001139662
          Length = 1660

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SGLGVMVAM 9
            SGL V +AM
Sbjct: 1427 SGLNVHIAM 1435
>NP_060227
          Length = 2248

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SGLGVMVAM 9
            SGL V +AM
Sbjct: 1427 SGLNVHIAM 1435
>XP_006722564
          Length = 1628

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SGLGVMVAM 9
            SGL V +AM
Sbjct: 1427 SGLNVHIAM 1435
>XP_006722563
          Length = 1630

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SGLGVMVAM 9
            SGL V +AM
Sbjct: 1427 SGLNVHIAM 1435
>XP_005266783
          Length = 2248

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    SGLGVMVAM 9
            SGL V +AM
Sbjct: 1427 SGLNVHIAM 1435
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.326    0.136    0.362 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 361,401
Number of extensions: 267
Number of successful extensions: 12
Number of sequences better than 10000.0: 12
Number of HSP's gapped: 12
Number of HSP's successfully gapped: 12
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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