Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006197                                                              22     103
XP_006714104                                                           22     103
XP_005265800                                                           22     103
XP_006714103                                                           22     103
XP_006714102                                                           22     103
XP_006715597                                                           17    4312
XP_005248809                                                           17    4312
NP_001695                                                              17    4312
NP_002244                                                              16    5631
NP_057647                                                              16    5631
NP_004775                                                              16    5631
XP_005254491                                                           16    5631
XP_005254490                                                           16    5631
XP_006714479                                                           16    5631
NP_996920                                                              16    7355
NP_001990                                                              16    7355
NP_996919                                                              16    7355
NP_996921                                                              16    7355
NP_003196                                                              16    7355
NP_057205                                                              16    7355
NP_002010                                                              16    7355
NP_001153392                                                           16    7355
NP_000867                                                              16    7355
NP_001153503                                                           16    7355
NP_001153502                                                           16    7355
NP_115823                                                              16    7355
NP_001002034                                                           16    7355
XP_005261430                                                           16    7355
XP_006722988                                                           16    7355
XP_006720722                                                           16    7355
XP_006720721                                                           16    7355
XP_005273215                                                           16    7355
XP_005273214                                                           16    7355
XP_005273213                                                           16    7355
NP_003836                                                              15    9605
NP_115518                                                              15    9605
NP_001124320                                                           15    9605
NP_004901                                                              15    9605
NP_067058                                                              15    9605
NP_001693                                                              15    9605
NP_001245304                                                           15    9605
NP_001245303                                                           15    9605
NP_061170                                                              15    9605
XP_006722890                                                           15    9605
XP_006722889                                                           15    9605
XP_006722888                                                           15    9605
XP_006722887                                                           15    9605
XP_006722886                                                           15    9605
XP_006722395                                                           15    9605
XP_006722392                                                           15    9605
XP_006722391                                                           15    9605
XP_006722390                                                           15    9605
XP_005258166                                                           15    9605
XP_006722389                                                           15    9605
XP_005258165                                                           15    9605
XP_005258164                                                           15    9605
XP_005251072                                                           15    9605
XP_005272088                                                           15    9605
NP_071414                                                              15    9605
>NP_006197
          Length = 1089

 Score = 21.9 bits (45), Expect =   103
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   SFDSRQGFN 9
           S+DSRQGFN
Sbjct: 171 SYDSRQGFN 179
>XP_006714104
          Length = 832

 Score = 21.9 bits (45), Expect =   103
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   SFDSRQGFN 9
           S+DSRQGFN
Sbjct: 196 SYDSRQGFN 204
>XP_005265800
          Length = 1089

 Score = 21.9 bits (45), Expect =   103
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   SFDSRQGFN 9
           S+DSRQGFN
Sbjct: 171 SYDSRQGFN 179
>XP_006714103
          Length = 1111

 Score = 21.9 bits (45), Expect =   103
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   SFDSRQGFN 9
           S+DSRQGFN
Sbjct: 193 SYDSRQGFN 201
>XP_006714102
          Length = 1114

 Score = 21.9 bits (45), Expect =   103
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   SFDSRQGFN 9
           S+DSRQGFN
Sbjct: 196 SYDSRQGFN 204
>XP_006715597
          Length = 1489

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    FDSRQGF 8
            FDS QGF
Sbjct: 1102 FDSLQGF 1108
>XP_005248809
          Length = 1522

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    FDSRQGF 8
            FDS QGF
Sbjct: 1135 FDSLQGF 1141
>NP_001695
          Length = 1522

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    FDSRQGF 8
            FDS QGF
Sbjct: 1135 FDSLQGF 1141
>NP_002244
          Length = 1356

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SFDSRQGF 8
           S+DS++GF
Sbjct: 178 SWDSKKGF 185
>NP_057647
          Length = 266

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SFDSRQGFN 9
           S DSRQ F+
Sbjct: 99  SVDSRQSFD 107
>NP_004775
          Length = 873

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SFDSRQGF 8
           +FDS +GF
Sbjct: 800 TFDSHKGF 807
>XP_005254491
          Length = 151

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SFDSRQGFN 9
           S DSRQ F+
Sbjct: 99  SVDSRQSFD 107
>XP_005254490
          Length = 247

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  SFDSRQGFN 9
          S DSRQ F+
Sbjct: 80 SVDSRQSFD 88
>XP_006714479
          Length = 873

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SFDSRQGF 8
           +FDS +GF
Sbjct: 800 TFDSHKGF 807
>NP_996920
          Length = 706

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  SFDSRQGF 8
          S+DS +GF
Sbjct: 69 SYDSSRGF 76
>NP_001990
          Length = 2912

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    FDSRQGF 8
            FD+RQ F
Sbjct: 2097 FDTRQSF 2103
>NP_996919
          Length = 706

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  SFDSRQGF 8
          S+DS +GF
Sbjct: 69 SYDSSRGF 76
>NP_996921
          Length = 682

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  SFDSRQGF 8
          S+DS +GF
Sbjct: 69 SYDSSRGF 76
>NP_003196
          Length = 682

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  SFDSRQGF 8
          S+DS +GF
Sbjct: 69 SYDSSRGF 76
>NP_057205
          Length = 815

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   SFDSRQGFN 9
           S DSR G N
Sbjct: 145 SADSRNGLN 153
>NP_002010
          Length = 1338

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   FDSRQGF 8
           +DSR+GF
Sbjct: 186 WDSRKGF 192
>NP_001153392
          Length = 687

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   FDSRQGF 8
           +DSR+GF
Sbjct: 186 WDSRKGF 192
>NP_000867
          Length = 2491

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   FDSRQGFN 9
           FDS+ GF+
Sbjct: 630 FDSQAGFS 637
>NP_001153503
          Length = 541

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   FDSRQGF 8
           +DSR+GF
Sbjct: 186 WDSRKGF 192
>NP_001153502
          Length = 733

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   FDSRQGF 8
           +DSR+GF
Sbjct: 186 WDSRKGF 192
>NP_115823
          Length = 2809

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    FDSRQGF 8
            FD+RQ F
Sbjct: 2010 FDTRQSF 2016
>NP_001002034
          Length = 259

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  SFDSRQG 7
          SF+SR+G
Sbjct: 54 SFESREG 60
>XP_005261430
          Length = 259

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  SFDSRQG 7
          SF+SR+G
Sbjct: 54 SFESREG 60
>XP_006722988
          Length = 2818

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    FDSRQGF 8
            FD+RQ F
Sbjct: 2019 FDTRQSF 2025
>XP_006720722
          Length = 681

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  SFDSRQGF 8
          S+DS +GF
Sbjct: 69 SYDSSRGF 76
>XP_006720721
          Length = 705

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  SFDSRQGF 8
          S+DS +GF
Sbjct: 69 SYDSSRGF 76
>XP_005273215
          Length = 713

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  SFDSRQGFN 9
          S DSR G N
Sbjct: 43 SADSRNGLN 51
>XP_005273214
          Length = 788

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   SFDSRQGFN 9
           S DSR G N
Sbjct: 118 SADSRNGLN 126
>XP_005273213
          Length = 813

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   SFDSRQGFN 9
           S DSR G N
Sbjct: 145 SADSRNGLN 153
>NP_003836
          Length = 520

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 1  SFDSRQGF 8
          SFD   GF
Sbjct: 84 SFDDEHGF 91
>NP_115518
          Length = 2537

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SFDSRQGFN 9
           SF+S+Q  N
Sbjct: 489 SFNSKQNLN 497
>NP_001124320
          Length = 1243

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   FDSRQGFN 9
           FD+ +GF+
Sbjct: 351 FDAHEGFS 358
>NP_004901
          Length = 1244

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   FDSRQGFN 9
           FD+ +GF+
Sbjct: 351 FDAHEGFS 358
>NP_067058
          Length = 864

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SFDSRQGF 8
           SF+S +GF
Sbjct: 734 SFNSAEGF 741
>NP_001693
          Length = 1584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    FDSRQGF 8
            FDS +GF
Sbjct: 1172 FDSLEGF 1178
>NP_001245304
          Length = 754

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SFDSRQGF 8
           SF+S +GF
Sbjct: 734 SFNSAEGF 741
>NP_001245303
          Length = 910

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SFDSRQGF 8
           SF+S +GF
Sbjct: 734 SFNSAEGF 741
>NP_061170
          Length = 728

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   DSRQGFN 9
           +SR GFN
Sbjct: 538 ESRAGFN 544
>XP_006722890
          Length = 750

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SFDSRQGF 8
           SF+S +GF
Sbjct: 734 SFNSAEGF 741
>XP_006722889
          Length = 796

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SFDSRQGF 8
           SF+S +GF
Sbjct: 734 SFNSAEGF 741
>XP_006722888
          Length = 797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SFDSRQGF 8
           SF+S +GF
Sbjct: 734 SFNSAEGF 741
>XP_006722887
          Length = 829

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SFDSRQGF 8
           SF+S +GF
Sbjct: 637 SFNSAEGF 644
>XP_006722886
          Length = 926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   SFDSRQGF 8
           SF+S +GF
Sbjct: 734 SFNSAEGF 741
>XP_006722395
          Length = 1419

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SFDSRQGFN 9
           SF+S+Q  N
Sbjct: 489 SFNSKQNLN 497
>XP_006722392
          Length = 2444

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SFDSRQGFN 9
           SF+S+Q  N
Sbjct: 395 SFNSKQNLN 403
>XP_006722391
          Length = 2448

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SFDSRQGFN 9
           SF+S+Q  N
Sbjct: 399 SFNSKQNLN 407
>XP_006722390
          Length = 2467

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SFDSRQGFN 9
           SF+S+Q  N
Sbjct: 489 SFNSKQNLN 497
>XP_005258166
          Length = 2468

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SFDSRQGFN 9
           SF+S+Q  N
Sbjct: 489 SFNSKQNLN 497
>XP_006722389
          Length = 2506

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SFDSRQGFN 9
           SF+S+Q  N
Sbjct: 489 SFNSKQNLN 497
>XP_005258165
          Length = 2534

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SFDSRQGFN 9
           SF+S+Q  N
Sbjct: 485 SFNSKQNLN 493
>XP_005258164
          Length = 2538

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   SFDSRQGFN 9
           SF+S+Q  N
Sbjct: 489 SFNSKQNLN 497
>XP_005251072
          Length = 1586

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    FDSRQGF 8
            FDS +GF
Sbjct: 1169 FDSLEGF 1175
>XP_005272088
          Length = 716

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   DSRQGFN 9
           +SR GFN
Sbjct: 526 ESRAGFN 532
>NP_071414
          Length = 955

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 2   FDSRQG 7
           FD RQG
Sbjct: 358 FDGRQG 363
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.321    0.135    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 590,743
Number of extensions: 914
Number of successful extensions: 59
Number of sequences better than 10000.0: 59
Number of HSP's gapped: 59
Number of HSP's successfully gapped: 59
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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