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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006197                                                              20     390
XP_005265800                                                           20     390
XP_006714103                                                           20     390
XP_006714102                                                           20     390
NP_005219                                                              17    4312
NP_001276866                                                           17    4312
NP_004439                                                              17    4312
NP_001276865                                                           17    4312
NP_001005862                                                           17    4312
XP_005257197                                                           17    4312
XP_006721828                                                           17    4312
NP_001036064                                                           16    5631
NP_005226                                                              16    5631
NP_001973                                                              16    5631
NP_004514                                                              16    5631
NP_002218                                                              16    5631
NP_002010                                                              16    5631
XP_005246434                                                           16    5631
XP_005246433                                                           16    5631
XP_005246432                                                           16    5631
XP_006712427                                                           16    5631
XP_005270898                                                           16    5631
XP_006710687                                                           16    5631
NP_002600                                                              16    7355
NP_002006                                                              16    7355
XP_005268521                                                           16    7355

>NP_006197
          Length = 1089

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   SEVYQIMVK 9
           SEVY+IMVK
Sbjct: 923 SEVYEIMVK 931



>XP_005265800
          Length = 1089

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   SEVYQIMVK 9
           SEVY+IMVK
Sbjct: 923 SEVYEIMVK 931



>XP_006714103
          Length = 1111

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   SEVYQIMVK 9
           SEVY+IMVK
Sbjct: 945 SEVYEIMVK 953



>XP_006714102
          Length = 1114

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   SEVYQIMVK 9
           SEVY+IMVK
Sbjct: 948 SEVYEIMVK 956



>NP_005219
          Length = 1210

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EVYQIMVK 9
           +VY IMVK
Sbjct: 942 DVYMIMVK 949



>NP_001276866
          Length = 1055

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EVYQIMVK 9
           +VY IMVK
Sbjct: 950 DVYMIMVK 957



>NP_004439
          Length = 1255

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EVYQIMVK 9
           +VY IMVK
Sbjct: 950 DVYMIMVK 957



>NP_001276865
          Length = 1240

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EVYQIMVK 9
           +VY IMVK
Sbjct: 935 DVYMIMVK 942



>NP_001005862
          Length = 1225

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EVYQIMVK 9
           +VY IMVK
Sbjct: 920 DVYMIMVK 927



>XP_005257197
          Length = 1225

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EVYQIMVK 9
           +VY IMVK
Sbjct: 920 DVYMIMVK 927



>XP_006721828
          Length = 1336

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    EVYQIMVK 9
            +VY IMVK
Sbjct: 1031 DVYMIMVK 1038



>NP_001036064
          Length = 1292

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EVYQIMVK 9
           +VY +MVK
Sbjct: 948 DVYMVMVK 955



>NP_005226
          Length = 1308

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EVYQIMVK 9
           +VY +MVK
Sbjct: 948 DVYMVMVK 955



>NP_001973
          Length = 1342

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EVYQIMVK 9
           +VY +MVK
Sbjct: 939 DVYMVMVK 946



>NP_004514
          Length = 1056

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EVYQIMVK 9
           EVYQI+ K
Sbjct: 209 EVYQILEK 216



>NP_002218
          Length = 1154

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    EVYQIMVK 9
            EVYQ+M K
Sbjct: 1123 EVYQLMRK 1130



>NP_002010
          Length = 1338

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    EVYQIMV 8
            E+YQIM+
Sbjct: 1128 EIYQIML 1134



>XP_005246434
          Length = 1282

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EVYQIMVK 9
           +VY +MVK
Sbjct: 938 DVYMVMVK 945



>XP_005246433
          Length = 1298

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EVYQIMVK 9
           +VY +MVK
Sbjct: 938 DVYMVMVK 945



>XP_005246432
          Length = 1307

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EVYQIMVK 9
           +VY +MVK
Sbjct: 963 DVYMVMVK 970



>XP_006712427
          Length = 1323

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EVYQIMVK 9
           +VY +MVK
Sbjct: 963 DVYMVMVK 970



>XP_005270898
          Length = 1154

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    EVYQIMVK 9
            EVYQ+M K
Sbjct: 1123 EVYQLMRK 1130



>XP_006710687
          Length = 1154

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    EVYQIMVK 9
            EVYQ+M K
Sbjct: 1123 EVYQLMRK 1130



>NP_002600
          Length = 1106

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EVYQIMVK 9
           E+Y+IM K
Sbjct: 932 EIYEIMQK 939



>NP_002006
          Length = 655

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   SEVYQIMVK 9
           S++Y+ MVK
Sbjct: 184 SQIYEWMVK 192



>XP_005268521
          Length = 1042

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EVYQIMVK 9
           E+Y+IM K
Sbjct: 868 EIYEIMQK 875



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.319    0.129    0.314 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 334,955
Number of extensions: 429
Number of successful extensions: 26
Number of sequences better than 10000.0: 26
Number of HSP's gapped: 26
Number of HSP's successfully gapped: 26
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)