Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001277144                                                           20     509
NP_001277143                                                           20     509
NP_001077383                                                           20     509
NP_001320                                                              20     509
NP_073713                                                              20     509
XP_005269629                                                           20     509
XP_005269628                                                           20     509
XP_005269627                                                           20     509
XP_005269626                                                           20     509
XP_006717706                                                           20     509
XP_005269625                                                           20     509
XP_005269624                                                           20     509
XP_006717705                                                           20     509
XP_005269622                                                           20     509
XP_005269621                                                           20     509
XP_006717704                                                           20     509
XP_005269619                                                           20     509
XP_005269618                                                           20     509
NP_001319                                                              18    1135
NP_001012632                                                           18    1135
XP_005272320                                                           18    1135
XP_005272319                                                           18    1135
XP_005272318                                                           18    1135
NP_003259                                                              18    1935
XP_006711570                                                           18    1935
XP_006711569                                                           18    1935
XP_006711568                                                           18    1935
XP_005273300                                                           18    1935
XP_006711567                                                           18    1935
XP_006711566                                                           18    1935
XP_005273298                                                           18    1935
XP_005273299                                                           18    1935
NP_055864                                                              17    3301
NP_055989                                                              17    4312
NP_001139112                                                           17    4312
NP_005076                                                              16    7355
XP_005272276                                                           16    7355
XP_005272275                                                           16    7355
XP_006717355                                                           16    7355
XP_005272274                                                           16    7355
XP_005272273                                                           16    7355
XP_005265867                                                           16    7355
XP_005265868                                                           16    7355
XP_005265869                                                           16    7355
XP_005265866                                                           16    7355
XP_005265865                                                           16    7355
XP_005265864                                                           16    7355
NP_001124336                                                           16    7355
NP_689522                                                              15    9605
XP_005269556                                                           15    9605
XP_005269555                                                           15    9605
>NP_001277144
          Length = 445

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SESFSFAQG 9
           SE FSFAQG
Sbjct: 300 SEPFSFAQG 308
>NP_001277143
          Length = 445

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SESFSFAQG 9
           SE FSFAQG
Sbjct: 300 SEPFSFAQG 308
>NP_001077383
          Length = 445

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SESFSFAQG 9
           SE FSFAQG
Sbjct: 300 SEPFSFAQG 308
>NP_001320
          Length = 445

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SESFSFAQG 9
           SE FSFAQG
Sbjct: 300 SEPFSFAQG 308
>NP_073713
          Length = 985

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SESFSFAQG 9
           SE FSFAQG
Sbjct: 840 SEPFSFAQG 848
>XP_005269629
          Length = 445

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SESFSFAQG 9
           SE FSFAQG
Sbjct: 300 SEPFSFAQG 308
>XP_005269628
          Length = 445

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SESFSFAQG 9
           SE FSFAQG
Sbjct: 300 SEPFSFAQG 308
>XP_005269627
          Length = 445

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SESFSFAQG 9
           SE FSFAQG
Sbjct: 300 SEPFSFAQG 308
>XP_005269626
          Length = 445

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SESFSFAQG 9
           SE FSFAQG
Sbjct: 300 SEPFSFAQG 308
>XP_006717706
          Length = 445

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SESFSFAQG 9
           SE FSFAQG
Sbjct: 300 SEPFSFAQG 308
>XP_005269625
          Length = 445

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SESFSFAQG 9
           SE FSFAQG
Sbjct: 300 SEPFSFAQG 308
>XP_005269624
          Length = 445

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SESFSFAQG 9
           SE FSFAQG
Sbjct: 300 SEPFSFAQG 308
>XP_006717705
          Length = 445

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SESFSFAQG 9
           SE FSFAQG
Sbjct: 300 SEPFSFAQG 308
>XP_005269622
          Length = 445

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SESFSFAQG 9
           SE FSFAQG
Sbjct: 300 SEPFSFAQG 308
>XP_005269621
          Length = 445

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SESFSFAQG 9
           SE FSFAQG
Sbjct: 300 SEPFSFAQG 308
>XP_006717704
          Length = 445

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SESFSFAQG 9
           SE FSFAQG
Sbjct: 300 SEPFSFAQG 308
>XP_005269619
          Length = 445

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SESFSFAQG 9
           SE FSFAQG
Sbjct: 300 SEPFSFAQG 308
>XP_005269618
          Length = 445

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SESFSFAQG 9
           SE FSFAQG
Sbjct: 300 SEPFSFAQG 308
>NP_001319
          Length = 440

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SESFSFAQG 9
           SE FSF+QG
Sbjct: 294 SEPFSFSQG 302
>NP_001012632
          Length = 429

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SESFSFAQG 9
           SE FSF+QG
Sbjct: 283 SEPFSFSQG 291
>XP_005272320
          Length = 430

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SESFSFAQG 9
           SE FSF+QG
Sbjct: 283 SEPFSFSQG 291
>XP_005272319
          Length = 430

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SESFSFAQG 9
           SE FSF+QG
Sbjct: 283 SEPFSFSQG 291
>XP_005272318
          Length = 441

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SESFSFAQG 9
           SE FSF+QG
Sbjct: 294 SEPFSFSQG 302
>NP_003259
          Length = 858

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ESFSFAQG 9
           E+FS+AQG
Sbjct: 770 EAFSYAQG 777
>XP_006711570
          Length = 858

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ESFSFAQG 9
           E+FS+AQG
Sbjct: 770 EAFSYAQG 777
>XP_006711569
          Length = 858

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ESFSFAQG 9
           E+FS+AQG
Sbjct: 770 EAFSYAQG 777
>XP_006711568
          Length = 858

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ESFSFAQG 9
           E+FS+AQG
Sbjct: 770 EAFSYAQG 777
>XP_005273300
          Length = 858

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ESFSFAQG 9
           E+FS+AQG
Sbjct: 770 EAFSYAQG 777
>XP_006711567
          Length = 858

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ESFSFAQG 9
           E+FS+AQG
Sbjct: 770 EAFSYAQG 777
>XP_006711566
          Length = 858

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ESFSFAQG 9
           E+FS+AQG
Sbjct: 770 EAFSYAQG 777
>XP_005273298
          Length = 858

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ESFSFAQG 9
           E+FS+AQG
Sbjct: 770 EAFSYAQG 777
>XP_005273299
          Length = 858

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ESFSFAQG 9
           E+FS+AQG
Sbjct: 770 EAFSYAQG 777
>NP_055864
          Length = 914

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SESFSFAQG 9
           +ESFS +QG
Sbjct: 198 NESFSLSQG 206
>NP_055989
          Length = 939

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  SESFSFAQG 9
          S+ F FAQG
Sbjct: 4  SQYFDFAQG 12
>NP_001139112
          Length = 70

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  SESFSFAQG 9
          S+ F FAQG
Sbjct: 4  SQYFDFAQG 12
>NP_005076
          Length = 2090

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    SESFSFAQ 8
            S SFSF Q
Sbjct: 1781 SSSFSFGQ 1788
>XP_005272276
          Length = 2036

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    SESFSFAQ 8
            S SFSF Q
Sbjct: 1727 SSSFSFGQ 1734
>XP_005272275
          Length = 2083

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    SESFSFAQ 8
            S SFSF Q
Sbjct: 1774 SSSFSFGQ 1781
>XP_006717355
          Length = 2120

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    SESFSFAQ 8
            S SFSF Q
Sbjct: 1811 SSSFSFGQ 1818
>XP_005272274
          Length = 2121

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    SESFSFAQ 8
            S SFSF Q
Sbjct: 1812 SSSFSFGQ 1819
>XP_005272273
          Length = 2132

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    SESFSFAQ 8
            S SFSF Q
Sbjct: 1823 SSSFSFGQ 1830
>XP_005265867
          Length = 538

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   SESFSFAQG 9
           SESF F  G
Sbjct: 384 SESFDFPPG 392
>XP_005265868
          Length = 538

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   SESFSFAQG 9
           SESF F  G
Sbjct: 384 SESFDFPPG 392
>XP_005265869
          Length = 538

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   SESFSFAQG 9
           SESF F  G
Sbjct: 384 SESFDFPPG 392
>XP_005265866
          Length = 538

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   SESFSFAQG 9
           SESF F  G
Sbjct: 384 SESFDFPPG 392
>XP_005265865
          Length = 538

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   SESFSFAQG 9
           SESF F  G
Sbjct: 384 SESFDFPPG 392
>XP_005265864
          Length = 538

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   SESFSFAQG 9
           SESF F  G
Sbjct: 384 SESFDFPPG 392
>NP_001124336
          Length = 755

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   SESFSFAQG 9
           SESF F  G
Sbjct: 601 SESFDFPPG 609
>NP_689522
          Length = 805

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   SESFSFAQ 8
           SESF F Q
Sbjct: 640 SESFRFQQ 647
>XP_005269556
          Length = 627

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   SESFSFAQ 8
           SESF F Q
Sbjct: 462 SESFRFQQ 469
>XP_005269555
          Length = 627

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   SESFSFAQ 8
           SESF F Q
Sbjct: 462 SESFRFQQ 469
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.309    0.118    0.308 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 420,133
Number of extensions: 664
Number of successful extensions: 51
Number of sequences better than 10000.0: 51
Number of HSP's gapped: 51
Number of HSP's successfully gapped: 51
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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