Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006197                                                              20     299
XP_006714104                                                           20     299
XP_005265800                                                           20     299
XP_006714103                                                           20     299
XP_006714102                                                           20     299
NP_003639                                                              17    2528
NP_690618                                                              17    2528
XP_005246166                                                           17    2528
XP_005246165                                                           17    2528
XP_005246164                                                           17    2528
NP_060822                                                              17    3301
NP_005436                                                              17    4312
NP_056503                                                              17    4312
NP_001008212                                                           16    5631
NP_068815                                                              16    5631
NP_001008214                                                           16    5631
NP_001008213                                                           16    5631
NP_076952                                                              16    5631
NP_932155                                                              16    5631
NP_001234940                                                           16    5631
XP_006723247                                                           16    5631
XP_005258908                                                           16    5631
XP_005258907                                                           16    5631
XP_006723246                                                           16    5631
XP_005258906                                                           16    5631
XP_005252395                                                           16    5631
XP_005252394                                                           16    5631
XP_005252393                                                           16    5631
NP_001025168                                                           16    5631
NP_001139137                                                           16    5631
NP_057028                                                              16    7355
NP_001139287                                                           16    7355
NP_003119                                                              16    7355
NP_689778                                                              16    7355
XP_005264575                                                           16    7355
XP_006712150                                                           16    7355
XP_005264574                                                           16    7355
NP_842565                                                              16    7355
NP_009148                                                              15    9605
NP_665858                                                              15    9605
NP_665859                                                              15    9605
NP_000133                                                              15    9605
NP_001099038                                                           15    9605
NP_001099037                                                           15    9605
NP_001099036                                                           15    9605
NP_071396                                                              15    9605
XP_006715230                                                           15    9605
XP_006715229                                                           15    9605
XP_005249350                                                           15    9605
XP_005249349                                                           15    9605
XP_005249348                                                           15    9605
XP_005249347                                                           15    9605
XP_005249346                                                           15    9605
XP_006713936                                                           15    9605
XP_006713935                                                           15    9605
XP_005247145                                                           15    9605
XP_005247144                                                           15    9605
XP_005247143                                                           15    9605
XP_006713548                                                           15    9605
XP_005245161                                                           15    9605
NP_037485                                                              15    9605
>NP_006197
          Length = 1089

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   SELEAVNLH 9
           S+LEAVNLH
Sbjct: 322 SQLEAVNLH 330
>XP_006714104
          Length = 832

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   SELEAVNLH 9
           S+LEAVNLH
Sbjct: 347 SQLEAVNLH 355
>XP_005265800
          Length = 1089

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   SELEAVNLH 9
           S+LEAVNLH
Sbjct: 322 SQLEAVNLH 330
>XP_006714103
          Length = 1111

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   SELEAVNLH 9
           S+LEAVNLH
Sbjct: 344 SQLEAVNLH 352
>XP_006714102
          Length = 1114

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   SELEAVNLH 9
           S+LEAVNLH
Sbjct: 347 SQLEAVNLH 355
>NP_003639
          Length = 1170

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SELEAVNLH 9
           SE++++NLH
Sbjct: 344 SEIDSLNLH 352
>NP_690618
          Length = 1214

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SELEAVNLH 9
           SE++++NLH
Sbjct: 388 SEIDSLNLH 396
>XP_005246166
          Length = 944

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SELEAVNLH 9
           SE++++NLH
Sbjct: 388 SEIDSLNLH 396
>XP_005246165
          Length = 1081

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SELEAVNLH 9
           SE++++NLH
Sbjct: 255 SEIDSLNLH 263
>XP_005246164
          Length = 1102

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   SELEAVNLH 9
           SE++++NLH
Sbjct: 276 SEIDSLNLH 284
>NP_060822
          Length = 203

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  SELEAVNLH 9
          SELE + LH
Sbjct: 87 SELEQIELH 95
>NP_005436
          Length = 1217

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SELEAVN 7
           SELEA+N
Sbjct: 864 SELEAIN 870
>NP_056503
          Length = 1060

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SELEAVNLH 9
           ++LEA NLH
Sbjct: 361 NDLEAGNLH 369
>NP_001008212
          Length = 577

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SELEAVNL 8
           SE+EA+NL
Sbjct: 297 SEVEALNL 304
>NP_068815
          Length = 577

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SELEAVNL 8
           SE+EA+NL
Sbjct: 297 SEVEALNL 304
>NP_001008214
          Length = 577

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SELEAVNL 8
           SE+EA+NL
Sbjct: 297 SEVEALNL 304
>NP_001008213
          Length = 577

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SELEAVNL 8
           SE+EA+NL
Sbjct: 297 SEVEALNL 304
>NP_076952
          Length = 350

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ELEAVNLH 9
           E EAVN H
Sbjct: 281 ETEAVNYH 288
>NP_932155
          Length = 300

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ELEAVNLH 9
           E EAVN H
Sbjct: 231 ETEAVNYH 238
>NP_001234940
          Length = 318

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ELEAVNLH 9
           E EAVN H
Sbjct: 249 ETEAVNYH 256
>XP_006723247
          Length = 566

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   SELEAVNLH 9
           ++LE++N+H
Sbjct: 438 NQLESLNMH 446
>XP_005258908
          Length = 567

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   SELEAVNLH 9
           ++LE++N+H
Sbjct: 439 NQLESLNMH 447
>XP_005258907
          Length = 570

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   SELEAVNLH 9
           ++LE++N+H
Sbjct: 442 NQLESLNMH 450
>XP_006723246
          Length = 571

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   SELEAVNLH 9
           ++LE++N+H
Sbjct: 443 NQLESLNMH 451
>XP_005258906
          Length = 571

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   SELEAVNLH 9
           ++LE++N+H
Sbjct: 443 NQLESLNMH 451
>XP_005252395
          Length = 520

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SELEAVNL 8
           SE+EA+NL
Sbjct: 240 SEVEALNL 247
>XP_005252394
          Length = 571

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SELEAVNL 8
           SE+EA+NL
Sbjct: 291 SEVEALNL 298
>XP_005252393
          Length = 571

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   SELEAVNL 8
           SE+EA+NL
Sbjct: 291 SEVEALNL 298
>NP_001025168
          Length = 571

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   SELEAVNLH 9
           ++LE++N+H
Sbjct: 443 NQLESLNMH 451
>NP_001139137
          Length = 570

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   SELEAVNLH 9
           ++LE++N+H
Sbjct: 442 NQLESLNMH 450
>NP_057028
          Length = 439

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SELEAVNLH 9
           S LEA +LH
Sbjct: 382 SALEAASLH 390
>NP_001139287
          Length = 594

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SELEAVNLH 9
           S LEA +LH
Sbjct: 382 SALEAASLH 390
>NP_003119
          Length = 2364

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ELEAVNLH 9
           ELEA N H
Sbjct: 487 ELEAENYH 494
>NP_689778
          Length = 350

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SELEAVNL 8
           +E+EAVN+
Sbjct: 136 TEMEAVNI 143
>XP_005264575
          Length = 2351

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ELEAVNLH 9
           ELEA N H
Sbjct: 474 ELEAENYH 481
>XP_006712150
          Length = 2364

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ELEAVNLH 9
           ELEA N H
Sbjct: 487 ELEAENYH 494
>XP_005264574
          Length = 2364

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ELEAVNLH 9
           ELEA N H
Sbjct: 487 ELEAENYH 494
>NP_842565
          Length = 2155

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ELEAVNLH 9
           ELEA N H
Sbjct: 474 ELEAENYH 481
>NP_009148
          Length = 212

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SELEAVNL 8
          +ELE VNL
Sbjct: 31 NELERVNL 38
>NP_665858
          Length = 212

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SELEAVNL 8
          +ELE VNL
Sbjct: 31 NELERVNL 38
>NP_665859
          Length = 212

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SELEAVNL 8
          +ELE VNL
Sbjct: 31 NELERVNL 38
>NP_000133
          Length = 806

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ELEAVNLH 9
           ELE ++LH
Sbjct: 320 ELEVLSLH 327
>NP_001099038
          Length = 1749

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    SELEAVN 7
            +ELEA+N
Sbjct: 1486 NELEAIN 1492
>NP_001099037
          Length = 1757

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    SELEAVN 7
            +ELEA+N
Sbjct: 1486 NELEAIN 1492
>NP_001099036
          Length = 1770

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    SELEAVN 7
            +ELEA+N
Sbjct: 1499 NELEAIN 1505
>NP_071396
          Length = 1805

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    SELEAVN 7
            +ELEA+N
Sbjct: 1534 NELEAIN 1540
>XP_006715230
          Length = 1734

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    SELEAVN 7
            +ELEA+N
Sbjct: 1463 NELEAIN 1469
>XP_006715229
          Length = 1782

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    SELEAVN 7
            +ELEA+N
Sbjct: 1511 NELEAIN 1517
>XP_005249350
          Length = 1810

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    SELEAVN 7
            +ELEA+N
Sbjct: 1539 NELEAIN 1545
>XP_005249349
          Length = 1824

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    SELEAVN 7
            +ELEA+N
Sbjct: 1553 NELEAIN 1559
>XP_005249348
          Length = 1832

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    SELEAVN 7
            +ELEA+N
Sbjct: 1561 NELEAIN 1567
>XP_005249347
          Length = 1837

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    SELEAVN 7
            +ELEA+N
Sbjct: 1574 NELEAIN 1580
>XP_005249346
          Length = 1845

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    SELEAVN 7
            +ELEA+N
Sbjct: 1574 NELEAIN 1580
>XP_006713936
          Length = 807

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ELEAVNLH 9
           ELE ++LH
Sbjct: 320 ELEVLSLH 327
>XP_006713935
          Length = 807

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ELEAVNLH 9
           ELE ++LH
Sbjct: 320 ELEVLSLH 327
>XP_005247145
          Length = 212

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SELEAVNL 8
          +ELE VNL
Sbjct: 31 NELERVNL 38
>XP_005247144
          Length = 212

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SELEAVNL 8
          +ELE VNL
Sbjct: 31 NELERVNL 38
>XP_005247143
          Length = 212

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SELEAVNL 8
          +ELE VNL
Sbjct: 31 NELERVNL 38
>XP_006713548
          Length = 212

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  SELEAVNL 8
          +ELE VNL
Sbjct: 31 NELERVNL 38
>XP_005245161
          Length = 306

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ELEAVNLH 9
           ELE VNL+
Sbjct: 157 ELEEVNLN 164
>NP_037485
          Length = 345

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ELEAVNLH 9
           ELE VNL+
Sbjct: 196 ELEEVNLN 203
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.304    0.121    0.303 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 461,252
Number of extensions: 828
Number of successful extensions: 61
Number of sequences better than 10000.0: 61
Number of HSP's gapped: 61
Number of HSP's successfully gapped: 61
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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