Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_055365                                                              19     869
NP_057427                                                              16    5631
NP_115791                                                              16    5631
NP_001099129                                                           16    5631
NP_001139745                                                           16    5631
XP_006715859                                                           16    5631
XP_006715858                                                           16    5631
XP_006715857                                                           16    5631
XP_006710416                                                           16    5631
XP_006710415                                                           16    5631
XP_005270511                                                           16    5631
XP_005270508                                                           16    5631
NP_001008495                                                           16    5631
NP_001184033                                                           16    7355
NP_005924                                                              16    7355
NP_006551                                                              16    7355
NP_941989                                                              16    7355
NP_001020767                                                           16    7355
XP_006718194                                                           16    7355
XP_006718193                                                           16    7355
XP_006718192                                                           16    7355
XP_006718191                                                           16    7355
XP_006718190                                                           16    7355
XP_005252813                                                           16    7355
XP_005252812                                                           16    7355
XP_006718189                                                           16    7355
XP_006718188                                                           16    7355
XP_006718187                                                           16    7355
XP_005252811                                                           16    7355
XP_006718186                                                           16    7355
XP_006718185                                                           16    7355
NP_443179                                                              15    9605
>NP_055365
          Length = 1032

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   EKNSAVLR 9
           EKNSAVLR
Sbjct: 219 EKNSAVLR 226
>NP_057427
          Length = 3114

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SEKNSAVLR 9
           S KNSA+L+
Sbjct: 821 SPKNSAILQ 829
>NP_115791
          Length = 1154

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EKNSAVLR 9
           EKN AV+R
Sbjct: 214 EKNMAVMR 221
>NP_001099129
          Length = 624

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SEKNSAVLR 9
           S KN+AVLR
Sbjct: 363 SLKNNAVLR 371

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EKNSAVLR 9
           EKN AVL+
Sbjct: 539 EKNEAVLK 546
>NP_001139745
          Length = 328

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SEKNSAVLR 9
           SEK SAV+R
Sbjct: 228 SEKLSAVIR 236
>XP_006715859
          Length = 854

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EKNSAVLR 9
           EKN AV+R
Sbjct: 214 EKNMAVMR 221
>XP_006715858
          Length = 1267

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EKNSAVLR 9
           EKN AV+R
Sbjct: 214 EKNMAVMR 221
>XP_006715857
          Length = 1268

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EKNSAVLR 9
           EKN AV+R
Sbjct: 214 EKNMAVMR 221
>XP_006710416
          Length = 304

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  SEKNSAVLR 9
          S KN+AVLR
Sbjct: 43 SLKNNAVLR 51

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EKNSAVLR 9
           EKN AVL+
Sbjct: 219 EKNEAVLK 226
>XP_006710415
          Length = 304

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  SEKNSAVLR 9
          S KN+AVLR
Sbjct: 43 SLKNNAVLR 51

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EKNSAVLR 9
           EKN AVL+
Sbjct: 219 EKNEAVLK 226
>XP_005270511
          Length = 304

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  SEKNSAVLR 9
          S KN+AVLR
Sbjct: 43 SLKNNAVLR 51

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EKNSAVLR 9
           EKN AVL+
Sbjct: 219 EKNEAVLK 226
>XP_005270508
          Length = 430

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SEKNSAVLR 9
           S KN+AVLR
Sbjct: 363 SLKNNAVLR 371
>NP_001008495
          Length = 380

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   SEKNSAVLR 9
           SEK SAV+R
Sbjct: 228 SEKLSAVIR 236
>NP_001184033
          Length = 3972

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SEKNSAVL 8
           S++NSA+L
Sbjct: 183 SDRNSAIL 190
>NP_005924
          Length = 3969

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   SEKNSAVL 8
           S++NSA+L
Sbjct: 183 SDRNSAIL 190
>NP_006551
          Length = 482

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SEKNSAV 7
           SEKN+AV
Sbjct: 99  SEKNNAV 105
>NP_941989
          Length = 483

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SEKNSAV 7
           SEKN+AV
Sbjct: 99  SEKNNAV 105
>NP_001020767
          Length = 486

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SEKNSAV 7
           SEKN+AV
Sbjct: 99  SEKNNAV 105
>XP_006718194
          Length = 487

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SEKNSAV 7
           SEKN+AV
Sbjct: 99  SEKNNAV 105
>XP_006718193
          Length = 487

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SEKNSAV 7
           SEKN+AV
Sbjct: 99  SEKNNAV 105
>XP_006718192
          Length = 487

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SEKNSAV 7
           SEKN+AV
Sbjct: 99  SEKNNAV 105
>XP_006718191
          Length = 487

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SEKNSAV 7
           SEKN+AV
Sbjct: 99  SEKNNAV 105
>XP_006718190
          Length = 513

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SEKNSAV 7
           SEKN+AV
Sbjct: 126 SEKNNAV 132
>XP_005252813
          Length = 514

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SEKNSAV 7
           SEKN+AV
Sbjct: 126 SEKNNAV 132
>XP_005252812
          Length = 519

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SEKNSAV 7
           SEKN+AV
Sbjct: 135 SEKNNAV 141
>XP_006718189
          Length = 519

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SEKNSAV 7
           SEKN+AV
Sbjct: 135 SEKNNAV 141
>XP_006718188
          Length = 522

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SEKNSAV 7
           SEKN+AV
Sbjct: 135 SEKNNAV 141
>XP_006718187
          Length = 522

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SEKNSAV 7
           SEKN+AV
Sbjct: 135 SEKNNAV 141
>XP_005252811
          Length = 523

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SEKNSAV 7
           SEKN+AV
Sbjct: 135 SEKNNAV 141
>XP_006718186
          Length = 523

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SEKNSAV 7
           SEKN+AV
Sbjct: 135 SEKNNAV 141
>XP_006718185
          Length = 523

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   SEKNSAV 7
           SEKN+AV
Sbjct: 135 SEKNNAV 141
>NP_443179
          Length = 2170

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  EKNSAVLR 9
          EK+ AVLR
Sbjct: 25 EKSDAVLR 32
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.295    0.109    0.244 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 423,607
Number of extensions: 551
Number of successful extensions: 36
Number of sequences better than 10000.0: 32
Number of HSP's gapped: 36
Number of HSP's successfully gapped: 36
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.1 bits)
S2: 28 (15.4 bits)

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