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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001268421                                                           19     869
NP_000170                                                              19     869
NP_001268422                                                           19     869
NP_001268423                                                           19     869
XP_005264328                                                           19     869
NP_877439                                                              16    7355
NP_000432                                                              15    9605
NP_003881                                                              15    9605
NP_001129284                                                           15    9605
NP_067061                                                              15    9605
XP_006725214                                                           15    9605
XP_006725213                                                           15    9605
XP_006725212                                                           15    9605
XP_005253515                                                           15    9605
XP_005253514                                                           15    9605
XP_005253513                                                           15    9605
XP_005250483                                                           15    9605
XP_006716087                                                           15    9605
XP_005250482                                                           15    9605
NP_001129283                                                           15    9605

>NP_001268421
          Length = 1230

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SDAVSTTRS 9
           SD VSTTRS
Sbjct: 584 SDTVSTTRS 592



>NP_000170
          Length = 1360

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SDAVSTTRS 9
           SD VSTTRS
Sbjct: 714 SDTVSTTRS 722



>NP_001268422
          Length = 1058

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SDAVSTTRS 9
           SD VSTTRS
Sbjct: 412 SDTVSTTRS 420



>NP_001268423
          Length = 1058

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SDAVSTTRS 9
           SD VSTTRS
Sbjct: 412 SDTVSTTRS 420



>XP_005264328
          Length = 1261

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   SDAVSTTRS 9
           SD VSTTRS
Sbjct: 615 SDTVSTTRS 623



>NP_877439
          Length = 852

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   SDAVSTTRS 9
           SD+V TTR+
Sbjct: 626 SDSVFTTRN 634



>NP_000432
          Length = 780

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SDAVSTTRS 9
           SDAVST  +
Sbjct: 606 SDAVSTNNA 614



>NP_003881
          Length = 5405

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    SDAVSTTRS 9
            S AVS TRS
Sbjct: 2123 SQAVSYTRS 2131




 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    SDAVSTTRS 9
            S AVS TRS
Sbjct: 3324 SQAVSYTRS 3332




 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    SDAVSTTRS 9
            S AVS TRS
Sbjct: 4525 SQAVSYTRS 4533



>NP_001129284
          Length = 221

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SDAVSTTRS 9
           SDA STT S
Sbjct: 120 SDAHSTTSS 128



>NP_067061
          Length = 221

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SDAVSTTRS 9
           SDA STT S
Sbjct: 120 SDAHSTTSS 128



>XP_006725214
          Length = 221

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SDAVSTTRS 9
           SDA STT S
Sbjct: 120 SDAHSTTSS 128



>XP_006725213
          Length = 221

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SDAVSTTRS 9
           SDA STT S
Sbjct: 120 SDAHSTTSS 128



>XP_006725212
          Length = 250

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SDAVSTTRS 9
           SDA STT S
Sbjct: 149 SDAHSTTSS 157



>XP_005253515
          Length = 221

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SDAVSTTRS 9
           SDA STT S
Sbjct: 120 SDAHSTTSS 128



>XP_005253514
          Length = 221

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SDAVSTTRS 9
           SDA STT S
Sbjct: 120 SDAHSTTSS 128



>XP_005253513
          Length = 250

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SDAVSTTRS 9
           SDA STT S
Sbjct: 149 SDAHSTTSS 157



>XP_005250483
          Length = 367

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SDAVSTTRS 9
           SDAVST  +
Sbjct: 193 SDAVSTNNA 201



>XP_006716087
          Length = 780

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SDAVSTTRS 9
           SDAVST  +
Sbjct: 606 SDAVSTNNA 614



>XP_005250482
          Length = 780

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   SDAVSTTRS 9
           SDAVST  +
Sbjct: 606 SDAVSTNNA 614



>NP_001129283
          Length = 221

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   SDAVSTTRS 9
           SDA STT S
Sbjct: 120 SDAHSTTSS 128



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.288   0.0947    0.211 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 264,919
Number of extensions: 329
Number of successful extensions: 22
Number of sequences better than 10000.0: 20
Number of HSP's gapped: 22
Number of HSP's successfully gapped: 22
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.0 bits)
S2: 28 (15.4 bits)