Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001136098                                                           19     665
NP_000360                                                              19     665
NP_001018046                                                           19     665
XP_005268096                                                           19     665
XP_006720308                                                           19     665
XP_005268094                                                           19     665
NP_064599                                                              17    3301
XP_005254616                                                           17    3301
XP_005254615                                                           17    3301
XP_005254614                                                           17    3301
NP_005329                                                              17    4312
XP_005250362                                                           17    4312
XP_005250361                                                           17    4312
NP_001161401                                                           16    5631
NP_002173                                                              16    5631
NP_001161403                                                           16    5631
NP_001161400                                                           16    5631
NP_001161402                                                           16    5631
NP_608273                                                              16    5631
XP_005247491                                                           16    5631
XP_005247490                                                           16    5631
NP_065783                                                              16    7355
NP_892006                                                              16    7355
NP_059989                                                              16    7355
NP_149062                                                              16    7355
NP_064627                                                              16    7355
NP_001157888                                                           16    7355
NP_001271210                                                           16    7355
XP_006724703                                                           16    7355
XP_005267899                                                           16    7355
XP_006720257                                                           16    7355
XP_006715590                                                           16    7355
XP_005267126                                                           16    7355
XP_006715589                                                           16    7355
XP_006715588                                                           16    7355
XP_006715587                                                           16    7355
XP_006715586                                                           16    7355
XP_006715488                                                           16    7355
XP_006715487                                                           16    7355
XP_006715486                                                           16    7355
XP_006715485                                                           16    7355
XP_006715484                                                           16    7355
XP_006715483                                                           16    7355
XP_006715482                                                           16    7355
XP_006715481                                                           16    7355
XP_006715480                                                           16    7355
XP_006715479                                                           16    7355
XP_006715478                                                           16    7355
XP_006715477                                                           16    7355
XP_006715476                                                           16    7355
XP_006715475                                                           16    7355
XP_006715474                                                           16    7355
XP_006715473                                                           16    7355
XP_006715472                                                           16    7355
XP_006715471                                                           16    7355
XP_006715470                                                           16    7355
XP_006713327                                                           16    7355
XP_006713325                                                           16    7355
XP_006713324                                                           16    7355
XP_005265385                                                           16    7355
NP_000375                                                              15    9605
NP_006266                                                              15    9605
NP_001161842                                                           15    9605
NP_001074260                                                           15    9605
NP_055595                                                              15    9605
NP_001276061                                                           15    9605
NP_443081                                                              15    9605
NP_001922                                                              15    9605
NP_037374                                                              15    9605
NP_006769                                                              15    9605
NP_001074261                                                           15    9605
XP_006715348                                                           15    9605
XP_005249560                                                           15    9605
>NP_001136098
          Length = 274

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  RVTSKDIQR 9
          RVT KDIQR
Sbjct: 38 RVTCKDIQR 46
>NP_000360
          Length = 764

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  RVTSKDIQR 9
          RVT KDIQR
Sbjct: 38 RVTCKDIQR 46
>NP_001018046
          Length = 253

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  RVTSKDIQR 9
          RVT KDIQR
Sbjct: 38 RVTCKDIQR 46
>XP_005268096
          Length = 253

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  RVTSKDIQR 9
          RVT KDIQR
Sbjct: 38 RVTCKDIQR 46
>XP_006720308
          Length = 274

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  RVTSKDIQR 9
          RVT KDIQR
Sbjct: 38 RVTCKDIQR 46
>XP_005268094
          Length = 764

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  RVTSKDIQR 9
          RVT KDIQR
Sbjct: 38 RVTCKDIQR 46
>NP_064599
          Length = 630

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VTSKDIQR 9
           +TSKD+Q+
Sbjct: 570 ITSKDLQK 577
>XP_005254616
          Length = 610

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VTSKDIQR 9
           +TSKD+Q+
Sbjct: 550 ITSKDLQK 557
>XP_005254615
          Length = 611

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VTSKDIQR 9
           +TSKD+Q+
Sbjct: 551 ITSKDLQK 558
>XP_005254614
          Length = 631

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VTSKDIQR 9
           +TSKD+Q+
Sbjct: 571 ITSKDLQK 578
>NP_005329
          Length = 1037

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VTSKDIQR 9
           V SKD+QR
Sbjct: 839 VASKDLQR 846
>XP_005250362
          Length = 1003

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VTSKDIQR 9
           V SKD+QR
Sbjct: 805 VASKDLQR 812
>XP_005250361
          Length = 1008

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VTSKDIQR 9
           V SKD+QR
Sbjct: 810 VASKDLQR 817
>NP_001161401
          Length = 570

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   RVTSKDIQR 9
           +VTS+D++R
Sbjct: 320 KVTSEDLKR 328
>NP_002173
          Length = 570

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   RVTSKDIQR 9
           +VTS+D++R
Sbjct: 320 KVTSEDLKR 328
>NP_001161403
          Length = 687

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   RVTSKDIQR 9
           +VTS+D++R
Sbjct: 320 KVTSEDLKR 328
>NP_001161400
          Length = 570

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   RVTSKDIQR 9
           +VTS+D++R
Sbjct: 320 KVTSEDLKR 328
>NP_001161402
          Length = 356

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   RVTSKDIQR 9
           +VTS+D++R
Sbjct: 320 KVTSEDLKR 328
>NP_608273
          Length = 356

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   RVTSKDIQR 9
           +VTS+D++R
Sbjct: 320 KVTSEDLKR 328
>XP_005247491
          Length = 493

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   RVTSKDIQR 9
           +VTS+D++R
Sbjct: 126 KVTSEDLKR 134
>XP_005247490
          Length = 687

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   RVTSKDIQR 9
           +VTS+D++R
Sbjct: 320 KVTSEDLKR 328
>NP_065783
          Length = 2249

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    RVTSKDI 7
            ++TSKDI
Sbjct: 1625 KITSKDI 1631
>NP_892006
          Length = 8797

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    RVTSKDIQR 9
            + T+KDIQ+
Sbjct: 4105 KTTAKDIQQ 4113
>NP_059989
          Length = 2236

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    RVTSKDI 7
            ++TSKDI
Sbjct: 1612 KITSKDI 1618
>NP_149062
          Length = 8749

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    RVTSKDIQR 9
            + T+KDIQ+
Sbjct: 4034 KTTAKDIQQ 4042
>NP_064627
          Length = 1388

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    RVTSKDIQR 9
            R+ S+DI+R
Sbjct: 1050 RILSEDIER 1058
>NP_001157888
          Length = 154

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VTSKDIQ 8
           +TS+DIQ
Sbjct: 112 ITSRDIQ 118
>NP_001271210
          Length = 594

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RVTSKDI 7
           ++TSKDI
Sbjct: 179 KITSKDI 185
>XP_006724703
          Length = 154

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VTSKDIQ 8
           +TS+DIQ
Sbjct: 112 ITSRDIQ 118
>XP_005267899
          Length = 833

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RVTSKDI 7
           ++TSKDI
Sbjct: 418 KITSKDI 424
>XP_006720257
          Length = 833

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RVTSKDI 7
           ++TSKDI
Sbjct: 418 KITSKDI 424
>XP_006715590
          Length = 2277

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    RVTSKDI 7
            ++TSKDI
Sbjct: 1653 KITSKDI 1659
>XP_005267126
          Length = 2316

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    RVTSKDI 7
            ++TSKDI
Sbjct: 1692 KITSKDI 1698
>XP_006715589
          Length = 2320

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    RVTSKDI 7
            ++TSKDI
Sbjct: 1696 KITSKDI 1702
>XP_006715588
          Length = 2330

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    RVTSKDI 7
            ++TSKDI
Sbjct: 1706 KITSKDI 1712
>XP_006715587
          Length = 2359

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    RVTSKDI 7
            ++TSKDI
Sbjct: 1735 KITSKDI 1741
>XP_006715586
          Length = 2373

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    RVTSKDI 7
            ++TSKDI
Sbjct: 1749 KITSKDI 1755
>XP_006715488
          Length = 8721

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    RVTSKDIQR 9
            + T+KDIQ+
Sbjct: 4112 KTTAKDIQQ 4120
>XP_006715487
          Length = 8744

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    RVTSKDIQR 9
            + T+KDIQ+
Sbjct: 4112 KTTAKDIQQ 4120
>XP_006715486
          Length = 8758

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    RVTSKDIQR 9
            + T+KDIQ+
Sbjct: 4112 KTTAKDIQQ 4120
>XP_006715485
          Length = 8793

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    RVTSKDIQR 9
            + T+KDIQ+
Sbjct: 4059 KTTAKDIQQ 4067
>XP_006715484
          Length = 8794

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    RVTSKDIQR 9
            + T+KDIQ+
Sbjct: 4060 KTTAKDIQQ 4068
>XP_006715483
          Length = 8795

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    RVTSKDIQR 9
            + T+KDIQ+
Sbjct: 4112 KTTAKDIQQ 4120
>XP_006715482
          Length = 8797

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    RVTSKDIQR 9
            + T+KDIQ+
Sbjct: 4105 KTTAKDIQQ 4113
>XP_006715481
          Length = 8799

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    RVTSKDIQR 9
            + T+KDIQ+
Sbjct: 4065 KTTAKDIQQ 4073
>XP_006715480
          Length = 8799

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    RVTSKDIQR 9
            + T+KDIQ+
Sbjct: 4112 KTTAKDIQQ 4120
>XP_006715479
          Length = 8804

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    RVTSKDIQR 9
            + T+KDIQ+
Sbjct: 4112 KTTAKDIQQ 4120
>XP_006715478
          Length = 8809

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    RVTSKDIQR 9
            + T+KDIQ+
Sbjct: 4112 KTTAKDIQQ 4120
>XP_006715477
          Length = 8822

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    RVTSKDIQR 9
            + T+KDIQ+
Sbjct: 4088 KTTAKDIQQ 4096
>XP_006715476
          Length = 8823

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    RVTSKDIQR 9
            + T+KDIQ+
Sbjct: 4112 KTTAKDIQQ 4120
>XP_006715475
          Length = 8827

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    RVTSKDIQR 9
            + T+KDIQ+
Sbjct: 4112 KTTAKDIQQ 4120
>XP_006715474
          Length = 8829

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    RVTSKDIQR 9
            + T+KDIQ+
Sbjct: 4095 KTTAKDIQQ 4103
>XP_006715473
          Length = 8832

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    RVTSKDIQR 9
            + T+KDIQ+
Sbjct: 4112 KTTAKDIQQ 4120
>XP_006715472
          Length = 8839

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    RVTSKDIQR 9
            + T+KDIQ+
Sbjct: 4105 KTTAKDIQQ 4113
>XP_006715471
          Length = 8842

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    RVTSKDIQR 9
            + T+KDIQ+
Sbjct: 4112 KTTAKDIQQ 4120
>XP_006715470
          Length = 8846

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    RVTSKDIQR 9
            + T+KDIQ+
Sbjct: 4112 KTTAKDIQQ 4120
>XP_006713327
          Length = 1023

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RVTSKDIQR 9
           R+ S+DI+R
Sbjct: 685 RILSEDIER 693
>XP_006713325
          Length = 1195

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    RVTSKDIQR 9
            R+ S+DI+R
Sbjct: 1050 RILSEDIER 1058
>XP_006713324
          Length = 1285

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    RVTSKDIQR 9
            R+ S+DI+R
Sbjct: 1050 RILSEDIER 1058
>XP_005265385
          Length = 1291

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RVTSKDIQR 9
           R+ S+DI+R
Sbjct: 953 RILSEDIER 961
>NP_000375
          Length = 4563

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    RVTSKDIQ 8
            R+T  DIQ
Sbjct: 2150 RITENDIQ 2157
>NP_006266
          Length = 344

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  VTSKDIQR 9
          V  KDIQR
Sbjct: 13 VREKDIQR 20
>NP_001161842
          Length = 1782

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    TSKDIQR 9
            TSK++QR
Sbjct: 1394 TSKELQR 1400
>NP_001074260
          Length = 194

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VTSKDIQR 9
           VTSKD+ R
Sbjct: 104 VTSKDMLR 111
>NP_055595
          Length = 1698

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    TSKDIQR 9
            TSK++QR
Sbjct: 1310 TSKELQR 1316
>NP_001276061
          Length = 134

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VTSKDIQR 9
           VTSKD+ R
Sbjct: 95  VTSKDMLR 102
>NP_443081
          Length = 185

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VTSKDIQR 9
           VTSKD+ R
Sbjct: 95  VTSKDMLR 102
>NP_001922
          Length = 647

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   RVTSKDI 7
           R+T KDI
Sbjct: 383 RITKKDI 389
>NP_037374
          Length = 193

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  RVTSKDIQ 8
          R+T  DIQ
Sbjct: 36 RITDNDIQ 43
>NP_006769
          Length = 481

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VTSKDIQR 9
           V S+D+QR
Sbjct: 383 VVSEDVQR 390
>NP_001074261
          Length = 185

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VTSKDIQR 9
           VTSKD+ R
Sbjct: 95  VTSKDMLR 102
>XP_006715348
          Length = 1734

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    TSKDIQR 9
            TSK++QR
Sbjct: 1342 TSKELQR 1348
>XP_005249560
          Length = 1750

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    TSKDIQR 9
            TSK++QR
Sbjct: 1362 TSKELQR 1368
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.319    0.128    0.317 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 439,227
Number of extensions: 588
Number of successful extensions: 73
Number of sequences better than 10000.0: 73
Number of HSP's gapped: 73
Number of HSP's successfully gapped: 73
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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