Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000258                                                              18    1482
NP_001035957                                                           18    1482
XP_006721990                                                           18    1482
XP_006721989                                                           18    1482
XP_005258041                                                           18    1482
XP_006721988                                                           18    1482
XP_006721987                                                           18    1482
XP_006721986                                                           18    1482
XP_005258040                                                           18    1482
XP_006721985                                                           18    1482
NP_002728                                                              17    3301
NP_001229713                                                           16    5631
NP_000402                                                              16    5631
NP_001229714                                                           16    5631
NP_115545                                                              16    5631
XP_006724059                                                           16    5631
XP_006724058                                                           16    5631
XP_006724057                                                           16    5631
XP_005261013                                                           16    5631
XP_005261012                                                           16    5631
XP_006724056                                                           16    5631
XP_005261010                                                           16    5631
NP_079421                                                              16    7355
NP_056504                                                              16    7355
NP_037373                                                              16    7355
XP_005255967                                                           16    7355
XP_005255966                                                           16    7355
XP_005270233                                                           16    7355
XP_005270231                                                           16    7355
XP_005270230                                                           16    7355
XP_005270229                                                           16    7355
XP_005270228                                                           16    7355
XP_005250035                                                           16    7355
XP_005250034                                                           16    7355
XP_005250033                                                           16    7355
NP_001074001                                                           16    7355
NP_001273331                                                           15    9605
NP_000237                                                              15    9605
NP_758963                                                              15    9605
NP_001129610                                                           15    9605
NP_631896                                                              15    9605
NP_001095139                                                           15    9605
NP_001274150                                                           15    9605
NP_005409                                                              15    9605
NP_003857                                                              15    9605
NP_998783                                                              15    9605
NP_036556                                                              15    9605
XP_006720946                                                           15    9605
XP_005255380                                                           15    9605
XP_006720945                                                           15    9605
XP_006720944                                                           15    9605
XP_005255378                                                           15    9605
XP_005255377                                                           15    9605
XP_006720943                                                           15    9605
XP_005253141                                                           15    9605
XP_005253140                                                           15    9605
XP_005253137                                                           15    9605
XP_005253136                                                           15    9605
XP_006718348                                                           15    9605
XP_006718347                                                           15    9605
XP_005253134                                                           15    9605
XP_006714467                                                           15    9605
XP_005263382                                                           15    9605
XP_005263381                                                           15    9605
XP_006714466                                                           15    9605
XP_005263380                                                           15    9605
XP_006714465                                                           15    9605
XP_005263379                                                           15    9605
XP_006714464                                                           15    9605
XP_006714463                                                           15    9605
XP_005273153                                                           15    9605
XP_006711335                                                           15    9605
>NP_000258
          Length = 2818

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RVIAILDKL 9
            RV AILDKL
Sbjct: 1949 RVTAILDKL 1957
>NP_001035957
          Length = 2839

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RVIAILDKL 9
            RV AILDKL
Sbjct: 1970 RVTAILDKL 1978
>XP_006721990
          Length = 2823

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RVIAILDKL 9
            RV AILDKL
Sbjct: 1980 RVTAILDKL 1988
>XP_006721989
          Length = 2823

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RVIAILDKL 9
            RV AILDKL
Sbjct: 1980 RVTAILDKL 1988
>XP_005258041
          Length = 2836

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RVIAILDKL 9
            RV AILDKL
Sbjct: 1949 RVTAILDKL 1957
>XP_006721988
          Length = 2846

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RVIAILDKL 9
            RV AILDKL
Sbjct: 1959 RVTAILDKL 1967
>XP_006721987
          Length = 2849

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RVIAILDKL 9
            RV AILDKL
Sbjct: 1980 RVTAILDKL 1988
>XP_006721986
          Length = 2854

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RVIAILDKL 9
            RV AILDKL
Sbjct: 1967 RVTAILDKL 1975
>XP_005258040
          Length = 2857

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RVIAILDKL 9
            RV AILDKL
Sbjct: 1970 RVTAILDKL 1978
>XP_006721985
          Length = 2867

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RVIAILDKL 9
            RV AILDKL
Sbjct: 1980 RVTAILDKL 1988
>NP_002728
          Length = 672

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   RVIAILDK 8
           RV+A+LDK
Sbjct: 389 RVLALLDK 396
>NP_001229713
          Length = 726

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RVIAILDKL 9
           RV+ +L+KL
Sbjct: 639 RVVTVLEKL 647
>NP_000402
          Length = 726

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RVIAILDKL 9
           RV+ +L+KL
Sbjct: 639 RVVTVLEKL 647
>NP_001229714
          Length = 726

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RVIAILDKL 9
           RV+ +L+KL
Sbjct: 639 RVVTVLEKL 647
>NP_115545
          Length = 780

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RVIAILD 7
           RVIA+LD
Sbjct: 236 RVIAVLD 242
>XP_006724059
          Length = 726

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RVIAILDKL 9
           RV+ +L+KL
Sbjct: 639 RVVTVLEKL 647
>XP_006724058
          Length = 726

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RVIAILDKL 9
           RV+ +L+KL
Sbjct: 639 RVVTVLEKL 647
>XP_006724057
          Length = 726

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RVIAILDKL 9
           RV+ +L+KL
Sbjct: 639 RVVTVLEKL 647
>XP_005261013
          Length = 726

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RVIAILDKL 9
           RV+ +L+KL
Sbjct: 639 RVVTVLEKL 647
>XP_005261012
          Length = 726

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RVIAILDKL 9
           RV+ +L+KL
Sbjct: 639 RVVTVLEKL 647
>XP_006724056
          Length = 821

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RVIAILDKL 9
           RV+ +L+KL
Sbjct: 734 RVVTVLEKL 742
>XP_005261010
          Length = 873

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RVIAILDKL 9
           RV+ +L+KL
Sbjct: 786 RVVTVLEKL 794
>NP_079421
          Length = 1665

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    RVIAILDKL 9
            + IA+LDK+
Sbjct: 1552 QTIAVLDKM 1560
>NP_056504
          Length = 1009

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   RVIAILDKL 9
           RVI I DKL
Sbjct: 767 RVIFIADKL 775
>NP_037373
          Length = 1164

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RVIAILDKL 9
           RV AIL+KL
Sbjct: 119 RVNAILEKL 127
>XP_005255967
          Length = 1154

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RVIAILDKL 9
           RV AIL+KL
Sbjct: 119 RVNAILEKL 127
>XP_005255966
          Length = 1190

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RVIAILDKL 9
           RV AIL+KL
Sbjct: 119 RVNAILEKL 127
>XP_005270233
          Length = 927

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RVIAILDKL 9
           + IA+LDK+
Sbjct: 814 QTIAVLDKM 822
>XP_005270231
          Length = 1627

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    RVIAILDKL 9
            + IA+LDK+
Sbjct: 1514 QTIAVLDKM 1522
>XP_005270230
          Length = 1627

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    RVIAILDKL 9
            + IA+LDK+
Sbjct: 1514 QTIAVLDKM 1522
>XP_005270229
          Length = 1637

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    RVIAILDKL 9
            + IA+LDK+
Sbjct: 1524 QTIAVLDKM 1532
>XP_005270228
          Length = 1666

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    RVIAILDKL 9
            + IA+LDK+
Sbjct: 1553 QTIAVLDKM 1561
>XP_005250035
          Length = 1009

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   RVIAILDKL 9
           RVI I DKL
Sbjct: 767 RVIFIADKL 775
>XP_005250034
          Length = 1009

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   RVIAILDKL 9
           RVI I DKL
Sbjct: 767 RVIFIADKL 775
>XP_005250033
          Length = 1009

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   RVIAILDKL 9
           RVI I DKL
Sbjct: 767 RVIFIADKL 775
>NP_001074001
          Length = 1100

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VIAILDKL 9
           +IA+LDK+
Sbjct: 411 IIALLDKV 418
>NP_001273331
          Length = 1131

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RVIAILDK 8
           RVIA+L K
Sbjct: 415 RVIAVLGK 422
>NP_000237
          Length = 1130

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RVIAILDK 8
           RVIA+L K
Sbjct: 414 RVIAVLGK 421
>NP_758963
          Length = 611

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VIAILDKL 9
           V+AILD L
Sbjct: 603 VVAILDHL 610
>NP_001129610
          Length = 1054

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   RVIAILDKL 9
           RV+ ++DK+
Sbjct: 329 RVLGVIDKV 337
>NP_631896
          Length = 717

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RVIAILDKL 9
           RVI + DKL
Sbjct: 478 RVIFVADKL 486
>NP_001095139
          Length = 924

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VIAILDKL 9
           +IA++DKL
Sbjct: 535 IIAMVDKL 542
>NP_001274150
          Length = 885

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   RVIAILDKL 9
           RV+ ++DK+
Sbjct: 160 RVLGVIDKV 168
>NP_005409
          Length = 1137

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RVIAILDKL 9
           RVI + DKL
Sbjct: 898 RVIFVADKL 906
>NP_003857
          Length = 924

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VIAILDKL 9
           +IA++DKL
Sbjct: 535 IIAMVDKL 542
>NP_998783
          Length = 1137

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RVIAILDKL 9
           RVI + DKL
Sbjct: 898 RVIFVADKL 906
>NP_036556
          Length = 1066

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   RVIAILDKL 9
           RV+ ++DK+
Sbjct: 341 RVLGVIDKV 349
>XP_006720946
          Length = 1081

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RVIAILDK 8
           RVIA+L K
Sbjct: 365 RVIAVLGK 372
>XP_005255380
          Length = 1082

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RVIAILDK 8
           RVIA+L K
Sbjct: 366 RVIAVLGK 373
>XP_006720945
          Length = 1096

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RVIAILDK 8
           RVIA+L K
Sbjct: 380 RVIAVLGK 387
>XP_006720944
          Length = 1097

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RVIAILDK 8
           RVIA+L K
Sbjct: 381 RVIAVLGK 388
>XP_005255378
          Length = 1145

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RVIAILDK 8
           RVIA+L K
Sbjct: 429 RVIAVLGK 436
>XP_005255377
          Length = 1146

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RVIAILDK 8
           RVIA+L K
Sbjct: 430 RVIAVLGK 437
>XP_006720943
          Length = 1208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RVIAILDK 8
           RVIA+L K
Sbjct: 492 RVIAVLGK 499
>XP_005253141
          Length = 717

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RVIAILDKL 9
           RVI + DKL
Sbjct: 478 RVIFVADKL 486
>XP_005253140
          Length = 717

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RVIAILDKL 9
           RVI + DKL
Sbjct: 478 RVIFVADKL 486
>XP_005253137
          Length = 1137

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RVIAILDKL 9
           RVI + DKL
Sbjct: 898 RVIFVADKL 906
>XP_005253136
          Length = 1137

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RVIAILDKL 9
           RVI + DKL
Sbjct: 898 RVIFVADKL 906
>XP_006718348
          Length = 1137

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RVIAILDKL 9
           RVI + DKL
Sbjct: 898 RVIFVADKL 906
>XP_006718347
          Length = 1137

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RVIAILDKL 9
           RVI + DKL
Sbjct: 898 RVIFVADKL 906
>XP_005253134
          Length = 1167

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RVIAILDKL 9
           RVI + DKL
Sbjct: 928 RVIFVADKL 936
>XP_006714467
          Length = 595

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VIAILDKL 9
           +IA++DKL
Sbjct: 544 IIAMVDKL 551
>XP_005263382
          Length = 753

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VIAILDKL 9
           +IA++DKL
Sbjct: 350 IIAMVDKL 357
>XP_005263381
          Length = 762

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VIAILDKL 9
           +IA++DKL
Sbjct: 359 IIAMVDKL 366
>XP_006714466
          Length = 762

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VIAILDKL 9
           +IA++DKL
Sbjct: 359 IIAMVDKL 366
>XP_005263380
          Length = 809

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VIAILDKL 9
           +IA++DKL
Sbjct: 406 IIAMVDKL 413
>XP_006714465
          Length = 924

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VIAILDKL 9
           +IA++DKL
Sbjct: 535 IIAMVDKL 542
>XP_005263379
          Length = 933

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VIAILDKL 9
           +IA++DKL
Sbjct: 544 IIAMVDKL 551
>XP_006714464
          Length = 938

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VIAILDKL 9
           +IA++DKL
Sbjct: 535 IIAMVDKL 542
>XP_006714463
          Length = 947

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VIAILDKL 9
           +IA++DKL
Sbjct: 544 IIAMVDKL 551
>XP_005273153
          Length = 885

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   RVIAILDKL 9
           RV+ ++DK+
Sbjct: 160 RVLGVIDKV 168
>XP_006711335
          Length = 945

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   RVIAILDKL 9
           RV+ ++DK+
Sbjct: 220 RVLGVIDKV 228
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.340    0.158    0.394 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 397,410
Number of extensions: 488
Number of successful extensions: 72
Number of sequences better than 10000.0: 72
Number of HSP's gapped: 72
Number of HSP's successfully gapped: 72
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)

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