Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_733751                                                              19     869
XP_006716142                                                           19     869
XP_005250088                                                           19     869
XP_006716141                                                           19     869
XP_005250085                                                           19     869
XP_006716140                                                           19     869
XP_005250084                                                           19     869
XP_005250083                                                           19     869
XP_005250082                                                           19     869
NP_689475                                                              18    1935
XP_006722996                                                           18    1935
XP_005260201                                                           18    1935
XP_005260199                                                           18    1935
NP_002068                                                              17    4312
XP_006717126                                                           17    4312
XP_005251986                                                           17    4312
XP_006717125                                                           17    4312
NP_001229695                                                           16    5631
NP_004737                                                              16    5631
NP_001003809                                                           16    5631
NP_001229693                                                           16    5631
NP_001229690                                                           16    5631
NP_001229692                                                           16    5631
NP_001229691                                                           16    5631
NP_001229694                                                           16    5631
XP_005258233                                                           16    5631
XP_005258232                                                           16    5631
XP_005258231                                                           16    5631
XP_006722430                                                           16    5631
XP_005258230                                                           16    5631
XP_005258229                                                           16    5631
XP_005258228                                                           16    5631
NP_001129465                                                           16    7355
NP_694943                                                              16    7355
XP_006722455                                                           16    7355
XP_005258255                                                           16    7355
NP_004250                                                              15    9605
NP_065829                                                              15    9605
XP_005257879                                                           15    9605
XP_006722249                                                           15    9605
XP_005257875                                                           15    9605
>NP_733751
          Length = 4911

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RSVSEESVN 9
           RSVSEES N
Sbjct: 110 RSVSEESAN 118
>XP_006716142
          Length = 4927

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RSVSEESVN 9
           RSVSEES N
Sbjct: 111 RSVSEESAN 119
>XP_005250088
          Length = 4928

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RSVSEESVN 9
           RSVSEES N
Sbjct: 111 RSVSEESAN 119
>XP_006716141
          Length = 4959

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RSVSEESVN 9
           RSVSEES N
Sbjct: 111 RSVSEESAN 119
>XP_005250085
          Length = 4979

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RSVSEESVN 9
           RSVSEES N
Sbjct: 111 RSVSEESAN 119
>XP_006716140
          Length = 4982

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RSVSEESVN 9
           RSVSEES N
Sbjct: 111 RSVSEESAN 119
>XP_005250084
          Length = 4982

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RSVSEESVN 9
           RSVSEES N
Sbjct: 111 RSVSEESAN 119
>XP_005250083
          Length = 4982

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RSVSEESVN 9
           RSVSEES N
Sbjct: 110 RSVSEESAN 118
>XP_005250082
          Length = 4983

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RSVSEESVN 9
           RSVSEES N
Sbjct: 111 RSVSEESAN 119
>NP_689475
          Length = 499

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  RSVSEESVN 9
          RSV+EE VN
Sbjct: 79 RSVTEEKVN 87
>XP_006722996
          Length = 404

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  RSVSEESVN 9
          RSV+EE VN
Sbjct: 84 RSVTEEKVN 92
>XP_005260201
          Length = 420

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  RSVSEESVN 9
          RSV+EE VN
Sbjct: 84 RSVTEEKVN 92
>XP_005260199
          Length = 504

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  RSVSEESVN 9
          RSV+EE VN
Sbjct: 84 RSVTEEKVN 92
>NP_002068
          Length = 767

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1  RSVSEESV 8
          RSVS+ESV
Sbjct: 27 RSVSKESV 34
>XP_006717126
          Length = 767

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1  RSVSEESV 8
          RSVS+ESV
Sbjct: 27 RSVSKESV 34
>XP_005251986
          Length = 767

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1  RSVSEESV 8
          RSVS+ESV
Sbjct: 27 RSVSKESV 34
>XP_006717125
          Length = 767

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1  RSVSEESV 8
          RSVS+ESV
Sbjct: 27 RSVSKESV 34
>NP_001229695
          Length = 685

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RSVSEESVN 9
           R+VSE S+N
Sbjct: 107 RAVSEVSIN 115
>NP_004737
          Length = 977

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RSVSEESVN 9
           R+VSE S+N
Sbjct: 409 RAVSEVSIN 417
>NP_001003809
          Length = 675

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RSVSEESVN 9
           R+VSE S+N
Sbjct: 107 RAVSEVSIN 115
>NP_001229693
          Length = 683

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RSVSEESVN 9
           R+VSE S+N
Sbjct: 115 RAVSEVSIN 123
>NP_001229690
          Length = 929

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RSVSEESVN 9
           R+VSE S+N
Sbjct: 409 RAVSEVSIN 417
>NP_001229692
          Length = 699

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RSVSEESVN 9
           R+VSE S+N
Sbjct: 121 RAVSEVSIN 129
>NP_001229691
          Length = 661

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RSVSEESVN 9
           R+VSE S+N
Sbjct: 121 RAVSEVSIN 129
>NP_001229694
          Length = 627

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RSVSEESVN 9
           R+VSE S+N
Sbjct: 107 RAVSEVSIN 115
>XP_005258233
          Length = 672

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RSVSEESVN 9
           R+VSE S+N
Sbjct: 94  RAVSEVSIN 102
>XP_005258232
          Length = 693

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RSVSEESVN 9
           R+VSE S+N
Sbjct: 115 RAVSEVSIN 123
>XP_005258231
          Length = 695

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RSVSEESVN 9
           R+VSE S+N
Sbjct: 117 RAVSEVSIN 125
>XP_006722430
          Length = 731

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RSVSEESVN 9
           R+VSE S+N
Sbjct: 153 RAVSEVSIN 161
>XP_005258230
          Length = 737

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RSVSEESVN 9
           R+VSE S+N
Sbjct: 159 RAVSEVSIN 167
>XP_005258229
          Length = 987

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RSVSEESVN 9
           R+VSE S+N
Sbjct: 409 RAVSEVSIN 417
>XP_005258228
          Length = 987

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RSVSEESVN 9
           R+VSE S+N
Sbjct: 409 RAVSEVSIN 417
>NP_001129465
          Length = 583

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VSEESVN 9
           VSEES+N
Sbjct: 207 VSEESLN 213
>NP_694943
          Length = 522

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VSEESVN 9
           VSEES+N
Sbjct: 146 VSEESLN 152
>XP_006722455
          Length = 329

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VSEESVN 9
           VSEES+N
Sbjct: 207 VSEESLN 213
>XP_005258255
          Length = 522

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VSEESVN 9
           VSEES+N
Sbjct: 146 VSEESLN 152
>NP_004250
          Length = 991

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RSVSEESVN 9
           RSV EE+ N
Sbjct: 957 RSVKEEAQN 965
>NP_065829
          Length = 1907

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RSVSEES 7
           RSVSE+S
Sbjct: 288 RSVSEDS 294
>XP_005257879
          Length = 586

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RSVSEESVN 9
           RSV EE+ N
Sbjct: 552 RSVKEEAQN 560
>XP_006722249
          Length = 607

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RSVSEESVN 9
           RSV EE+ N
Sbjct: 573 RSVKEEAQN 581
>XP_005257875
          Length = 1012

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RSVSEESVN 9
           RSV EE+ N
Sbjct: 978 RSVKEEAQN 986
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.281   0.0999    0.213 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 404,620
Number of extensions: 445
Number of successful extensions: 41
Number of sequences better than 10000.0: 41
Number of HSP's gapped: 41
Number of HSP's successfully gapped: 41
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.7 bits)
S2: 28 (15.4 bits)

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