Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_055365                                                              18    1135
XP_005269076                                                           17    4312
NP_001166935                                                           16    7355
NP_057726                                                              16    7355
NP_060111                                                              16    7355
NP_001166934                                                           16    7355
NP_001166936                                                           16    7355
XP_005254495                                                           16    7355
XP_006719559                                                           16    7355
XP_006719558                                                           16    7355
XP_005269072                                                           16    7355
XP_005269071                                                           16    7355
XP_005269070                                                           16    7355
XP_006719557                                                           16    7355
XP_005269069                                                           16    7355
XP_006719556                                                           16    7355
XP_005269068                                                           16    7355
XP_005269067                                                           16    7355
XP_005269066                                                           16    7355
XP_005269065                                                           16    7355
XP_005269064                                                           16    7355
NP_001079990                                                           16    7355
NP_036469                                                              15    9605
NP_001018008                                                           15    9605
NP_001008723                                                           15    9605
NP_001276332                                                           15    9605
NP_001276334                                                           15    9605
NP_071757                                                              15    9605
NP_665803                                                              15    9605
XP_005274634                                                           15    9605
XP_005274633                                                           15    9605
XP_005254710                                                           15    9605
XP_005254709                                                           15    9605
XP_005254708                                                           15    9605
XP_005254707                                                           15    9605
XP_005254706                                                           15    9605
XP_005254705                                                           15    9605
XP_005254704                                                           15    9605
XP_005254703                                                           15    9605
XP_006718007                                                           15    9605
>NP_055365
          Length = 1032

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   SRIRAIQE 9
           SRIRAIQE
Sbjct: 906 SRIRAIQE 913
>XP_005269076
          Length = 368

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  SRIRAIQE 9
          SRIRA++E
Sbjct: 6  SRIRAVRE 13
>NP_001166935
          Length = 1674

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RSRIRAIQE 9
           R RI+A+QE
Sbjct: 436 RVRIKAMQE 444
>NP_057726
          Length = 3674

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    RSRIRAIQE 9
            R ++RA+QE
Sbjct: 1709 REQLRALQE 1717
>NP_060111
          Length = 1661

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RSRIRAIQE 9
           R RI+A+QE
Sbjct: 436 RVRIKAMQE 444
>NP_001166934
          Length = 1637

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RSRIRAIQE 9
           R RI+A+QE
Sbjct: 436 RVRIKAMQE 444
>NP_001166936
          Length = 1621

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RSRIRAIQE 9
           R RI+A+QE
Sbjct: 436 RVRIKAMQE 444
>XP_005254495
          Length = 3694

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    RSRIRAIQE 9
            R ++RA+QE
Sbjct: 1729 REQLRALQE 1737
>XP_006719559
          Length = 1650

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RSRIRAIQE 9
           R RI+A+QE
Sbjct: 436 RVRIKAMQE 444
>XP_006719558
          Length = 1644

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RSRIRAIQE 9
           R RI+A+QE
Sbjct: 436 RVRIKAMQE 444
>XP_005269072
          Length = 1607

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RSRIRAIQE 9
           R RI+A+QE
Sbjct: 436 RVRIKAMQE 444
>XP_005269071
          Length = 1614

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RSRIRAIQE 9
           R RI+A+QE
Sbjct: 436 RVRIKAMQE 444
>XP_005269070
          Length = 1627

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RSRIRAIQE 9
           R RI+A+QE
Sbjct: 436 RVRIKAMQE 444
>XP_006719557
          Length = 1631

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RSRIRAIQE 9
           R RI+A+QE
Sbjct: 436 RVRIKAMQE 444
>XP_005269069
          Length = 1632

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RSRIRAIQE 9
           R RI+A+QE
Sbjct: 436 RVRIKAMQE 444
>XP_006719556
          Length = 1655

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RSRIRAIQE 9
           R RI+A+QE
Sbjct: 436 RVRIKAMQE 444
>XP_005269068
          Length = 1657

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RSRIRAIQE 9
           R RI+A+QE
Sbjct: 436 RVRIKAMQE 444
>XP_005269067
          Length = 1662

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RSRIRAIQE 9
           R RI+A+QE
Sbjct: 436 RVRIKAMQE 444
>XP_005269066
          Length = 1668

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RSRIRAIQE 9
           R RI+A+QE
Sbjct: 436 RVRIKAMQE 444
>XP_005269065
          Length = 1670

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RSRIRAIQE 9
           R RI+A+QE
Sbjct: 436 RVRIKAMQE 444
>XP_005269064
          Length = 1675

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RSRIRAIQE 9
           R RI+A+QE
Sbjct: 436 RVRIKAMQE 444
>NP_001079990
          Length = 74

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  RSRIRAIQE 9
          RSR+RA  E
Sbjct: 12 RSRLRAFPE 20
>NP_036469
          Length = 551

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SRIRAIQE 9
           +R+RA+QE
Sbjct: 370 ARLRAMQE 377
>NP_001018008
          Length = 245

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  RSRIRAIQE 9
          R +IR++QE
Sbjct: 11 RRKIRSLQE 19
>NP_001008723
          Length = 872

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RSRIRAIQE 9
           R+R RA++E
Sbjct: 694 RTRCRALEE 702
>NP_001276332
          Length = 987

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  RSRIRAIQ 8
          R+R RAIQ
Sbjct: 63 RTRARAIQ 70
>NP_001276334
          Length = 1030

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  RSRIRAIQ 8
          R+R RAIQ
Sbjct: 63 RTRARAIQ 70
>NP_071757
          Length = 1030

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  RSRIRAIQ 8
          R+R RAIQ
Sbjct: 63 RTRARAIQ 70
>NP_665803
          Length = 1025

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RSRIRAIQE 9
           R+R +A+QE
Sbjct: 711 RTRTKALQE 719
>XP_005274634
          Length = 710

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  RIRAIQE 9
          R+R+IQE
Sbjct: 8  RVRSIQE 14
>XP_005274633
          Length = 711

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  RIRAIQE 9
          R+R+IQE
Sbjct: 8  RVRSIQE 14
>XP_005254710
          Length = 245

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  RSRIRAIQE 9
          R +IR++QE
Sbjct: 11 RRKIRSLQE 19
>XP_005254709
          Length = 248

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  RSRIRAIQE 9
          R +IR++QE
Sbjct: 11 RRKIRSLQE 19
>XP_005254708
          Length = 248

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  RSRIRAIQE 9
          R +IR++QE
Sbjct: 11 RRKIRSLQE 19
>XP_005254707
          Length = 248

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  RSRIRAIQE 9
          R +IR++QE
Sbjct: 11 RRKIRSLQE 19
>XP_005254706
          Length = 248

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  RSRIRAIQE 9
          R +IR++QE
Sbjct: 11 RRKIRSLQE 19
>XP_005254705
          Length = 248

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  RSRIRAIQE 9
          R +IR++QE
Sbjct: 11 RRKIRSLQE 19
>XP_005254704
          Length = 251

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  RSRIRAIQE 9
          R +IR++QE
Sbjct: 11 RRKIRSLQE 19
>XP_005254703
          Length = 275

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  RSRIRAIQE 9
          R +IR++QE
Sbjct: 11 RRKIRSLQE 19
>XP_006718007
          Length = 1050

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  RSRIRAIQ 8
          R+R RAIQ
Sbjct: 84 RTRARAIQ 91
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.330    0.135    0.322 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 343,581
Number of extensions: 526
Number of successful extensions: 40
Number of sequences better than 10000.0: 40
Number of HSP's gapped: 40
Number of HSP's successfully gapped: 40
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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