Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005148                                                              19     665
NP_009297                                                              19     665
NP_113676                                                              18    1935
NP_065996                                                              17    4312
NP_060113                                                              17    4312
XP_006722025                                                           17    4312
XP_006722024                                                           17    4312
XP_005257527                                                           17    4312
XP_005257526                                                           17    4312
XP_005257525                                                           17    4312
XP_005257524                                                           17    4312
XP_005270063                                                           17    4312
XP_005270062                                                           17    4312
XP_005270061                                                           17    4312
NP_006341                                                              16    5631
NP_037541                                                              16    5631
NP_057413                                                              16    5631
NP_001032309                                                           16    5631
XP_005258934                                                           16    5631
XP_005258933                                                           16    5631
XP_005248460                                                           16    5631
XP_005248459                                                           16    5631
XP_005248458                                                           16    5631
XP_005248457                                                           16    5631
XP_006713267                                                           16    5631
XP_005265278                                                           16    5631
XP_006713266                                                           16    5631
NP_001165450                                                           16    5631
NP_056481                                                              16    7355
NP_001265473                                                           16    7355
NP_000057                                                              16    7355
NP_055524                                                              16    7355
NP_001265472                                                           16    7355
XP_006723838                                                           16    7355
XP_005260450                                                           16    7355
XP_006723837                                                           16    7355
XP_006723836                                                           16    7355
XP_006723835                                                           16    7355
XP_005271223                                                           16    7355
XP_006710936                                                           16    7355
NP_005111                                                              15    9605
NP_055603                                                              15    9605
NP_150088                                                              15    9605
NP_002902                                                              15    9605
NP_064733                                                              15    9605
NP_001004419                                                           15    9605
NP_037401                                                              15    9605
NP_001184246                                                           15    9605
XP_005262376                                                           15    9605
XP_005262374                                                           15    9605
XP_005260072                                                           15    9605
XP_006719748                                                           15    9605
XP_006718983                                                           15    9605
XP_006718982                                                           15    9605
XP_006718981                                                           15    9605
XP_006718980                                                           15    9605
XP_006718979                                                           15    9605
XP_006717402                                                           15    9605
XP_006717401                                                           15    9605
XP_005252380                                                           15    9605
XP_005252379                                                           15    9605
XP_005252378                                                           15    9605
XP_005252377                                                           15    9605
XP_005248339                                                           15    9605
NP_079280                                                              15    9605
>NP_005148
          Length = 1130

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RSILLRYEG 9
           RSI LRYEG
Sbjct: 161 RSISLRYEG 169
>NP_009297
          Length = 1149

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RSILLRYEG 9
           RSI LRYEG
Sbjct: 180 RSISLRYEG 188
>NP_113676
          Length = 705

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ILLRYEG 9
           +LLRYEG
Sbjct: 243 VLLRYEG 249
>NP_065996
          Length = 3184

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ILLRYEG 9
           +LLRY+G
Sbjct: 321 VLLRYDG 327
>NP_060113
          Length = 628

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LLRYEG 9
           LLRYEG
Sbjct: 206 LLRYEG 211
>XP_006722025
          Length = 464

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  LLRYEG 9
          LLRYEG
Sbjct: 42 LLRYEG 47
>XP_006722024
          Length = 523

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LLRYEG 9
           LLRYEG
Sbjct: 231 LLRYEG 236
>XP_005257527
          Length = 628

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LLRYEG 9
           LLRYEG
Sbjct: 206 LLRYEG 211
>XP_005257526
          Length = 630

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LLRYEG 9
           LLRYEG
Sbjct: 208 LLRYEG 213
>XP_005257525
          Length = 651

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LLRYEG 9
           LLRYEG
Sbjct: 229 LLRYEG 234
>XP_005257524
          Length = 653

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   LLRYEG 9
           LLRYEG
Sbjct: 231 LLRYEG 236
>XP_005270063
          Length = 2005

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ILLRYEG 9
           +LLRY+G
Sbjct: 321 VLLRYDG 327
>XP_005270062
          Length = 3184

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ILLRYEG 9
           +LLRY+G
Sbjct: 321 VLLRYDG 327
>XP_005270061
          Length = 3184

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ILLRYEG 9
           +LLRY+G
Sbjct: 321 VLLRYDG 327
>NP_006341
          Length = 317

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   RSILLRYEG 9
           RSI L YEG
Sbjct: 229 RSIGLAYEG 237
>NP_037541
          Length = 344

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   RSILLRYEG 9
           RSI L YEG
Sbjct: 229 RSIGLAYEG 237
>NP_057413
          Length = 866

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  ILLRYEG 9
          +LLRY+G
Sbjct: 80 LLLRYDG 86
>NP_001032309
          Length = 432

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RSILLRYEG 9
           RS L+R+EG
Sbjct: 420 RSDLIRHEG 428
>XP_005258934
          Length = 411

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RSILLRYEG 9
           RS L+R+EG
Sbjct: 399 RSDLIRHEG 407
>XP_005258933
          Length = 432

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RSILLRYEG 9
           RS L+R+EG
Sbjct: 420 RSDLIRHEG 428
>XP_005248460
          Length = 316

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   RSILLRYEG 9
           RSI L YEG
Sbjct: 229 RSIGLAYEG 237
>XP_005248459
          Length = 330

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   RSILLRYEG 9
           RSI L YEG
Sbjct: 229 RSIGLAYEG 237
>XP_005248458
          Length = 343

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   RSILLRYEG 9
           RSI L YEG
Sbjct: 229 RSIGLAYEG 237
>XP_005248457
          Length = 357

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   RSILLRYEG 9
           RSI L YEG
Sbjct: 229 RSIGLAYEG 237
>XP_006713267
          Length = 866

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  ILLRYEG 9
          +LLRY+G
Sbjct: 80 LLLRYDG 86
>XP_005265278
          Length = 866

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  ILLRYEG 9
          +LLRY+G
Sbjct: 80 LLLRYDG 86
>XP_006713266
          Length = 866

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  ILLRYEG 9
          +LLRY+G
Sbjct: 80 LLLRYDG 86
>NP_001165450
          Length = 513

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RSILLRYEG 9
           RS L+R+EG
Sbjct: 501 RSDLIRHEG 509
>NP_056481
          Length = 406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SILLRYEG 9
           S+L RY+G
Sbjct: 127 SVLSRYQG 134
>NP_001265473
          Length = 529

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RSILLRYE 8
           RS++L YE
Sbjct: 247 RSLMLHYE 254
>NP_000057
          Length = 591

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RSILLRYE 8
           RS++L YE
Sbjct: 309 RSLMLHYE 316
>NP_055524
          Length = 3546

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    SILLRYEG 9
            S+L+ YEG
Sbjct: 3170 SVLVAYEG 3177
>NP_001265472
          Length = 539

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RSILLRYE 8
           RS++L YE
Sbjct: 257 RSLMLHYE 264
>XP_006723838
          Length = 406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SILLRYEG 9
           S+L RY+G
Sbjct: 127 SVLSRYQG 134
>XP_005260450
          Length = 406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SILLRYEG 9
           S+L RY+G
Sbjct: 127 SVLSRYQG 134
>XP_006723837
          Length = 422

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SILLRYEG 9
           S+L RY+G
Sbjct: 143 SVLSRYQG 150
>XP_006723836
          Length = 434

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SILLRYEG 9
           S+L RY+G
Sbjct: 155 SVLSRYQG 162
>XP_006723835
          Length = 434

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SILLRYEG 9
           S+L RY+G
Sbjct: 155 SVLSRYQG 162
>XP_005271223
          Length = 628

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RSILLRYE 8
           RS++L YE
Sbjct: 346 RSLMLHYE 353
>XP_006710936
          Length = 630

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RSILLRYE 8
           RS++L YE
Sbjct: 348 RSLMLHYE 355
>NP_005111
          Length = 2177

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   ILLRYEG 9
           +LLRY G
Sbjct: 279 LLLRYSG 285
>NP_055603
          Length = 442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RSILLRY 7
           RS+LL+Y
Sbjct: 259 RSLLLKY 265
>NP_150088
          Length = 442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RSILLRY 7
           RS+LL+Y
Sbjct: 259 RSLLLKY 265
>NP_002902
          Length = 1118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   ILLRYE 8
           +LLRYE
Sbjct: 292 VLLRYE 297
>NP_064733
          Length = 546

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RSILLRYEG 9
           RS+ L+Y+G
Sbjct: 292 RSLRLQYKG 300
>NP_001004419
          Length = 194

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SILLRYEG 9
           + LLRY+G
Sbjct: 120 NFLLRYKG 127
>NP_037401
          Length = 191

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   SILLRYEG 9
           + LLRY+G
Sbjct: 120 NFLLRYKG 127
>NP_001184246
          Length = 154

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  SILLRYEG 9
          + LLRY+G
Sbjct: 83 NFLLRYKG 90
>XP_005262376
          Length = 2155

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   ILLRYEG 9
           +LLRY G
Sbjct: 279 LLLRYSG 285
>XP_005262374
          Length = 2180

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   ILLRYEG 9
           +LLRY G
Sbjct: 279 LLLRYSG 285
>XP_005260072
          Length = 1129

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   ILLRYE 8
           +LLRYE
Sbjct: 292 VLLRYE 297
>XP_006719748
          Length = 545

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RSILLRYEG 9
           RS+ L+Y+G
Sbjct: 291 RSLRLQYKG 299
>XP_006718983
          Length = 702

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RSILLRYE 8
           +SILL+Y+
Sbjct: 438 QSILLKYQ 445
>XP_006718982
          Length = 727

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RSILLRYE 8
           +SILL+Y+
Sbjct: 438 QSILLKYQ 445
>XP_006718981
          Length = 763

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RSILLRYE 8
           +SILL+Y+
Sbjct: 438 QSILLKYQ 445
>XP_006718980
          Length = 779

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RSILLRYE 8
           +SILL+Y+
Sbjct: 438 QSILLKYQ 445
>XP_006718979
          Length = 844

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RSILLRYE 8
           +SILL+Y+
Sbjct: 438 QSILLKYQ 445
>XP_006717402
          Length = 392

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RSILLRY 7
           RS+LL+Y
Sbjct: 209 RSLLLKY 215
>XP_006717401
          Length = 392

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RSILLRY 7
           RS+LL+Y
Sbjct: 209 RSLLLKY 215
>XP_005252380
          Length = 442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RSILLRY 7
           RS+LL+Y
Sbjct: 259 RSLLLKY 265
>XP_005252379
          Length = 442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RSILLRY 7
           RS+LL+Y
Sbjct: 259 RSLLLKY 265
>XP_005252378
          Length = 442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RSILLRY 7
           RS+LL+Y
Sbjct: 259 RSLLLKY 265
>XP_005252377
          Length = 442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RSILLRY 7
           RS+LL+Y
Sbjct: 259 RSLLLKY 265
>XP_005248339
          Length = 2584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  SILLRY 7
          SILLRY
Sbjct: 12 SILLRY 17
>NP_079280
          Length = 951

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RSILLRYE 8
           +SILL+Y+
Sbjct: 438 QSILLKYQ 445
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.328    0.151    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 437,714
Number of extensions: 747
Number of successful extensions: 65
Number of sequences better than 10000.0: 65
Number of HSP's gapped: 65
Number of HSP's successfully gapped: 65
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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