Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results 
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done




                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000537                                                              17    2528
NP_001263689                                                           17    2528
NP_001119584                                                           17    2528
NP_001119586                                                           17    2528
NP_001263625                                                           17    2528
NP_001119590                                                           17    2528
NP_001263690                                                           17    2528
NP_001119585                                                           17    2528
NP_001263624                                                           17    2528
NP_001119588                                                           17    2528
NP_001119587                                                           17    2528
NP_001119589                                                           17    2528
NP_001263627                                                           17    2528
NP_001263628                                                           17    2528
NP_001263626                                                           17    2528
NP_071940                                                              16    7355
XP_005268066                                                           16    7355
NP_775924                                                              15    9605
NP_848599                                                              15    9605
NP_005952                                                              15    9605
XP_006713081                                                           15    9605
NP_112208                                                              15    9605



>NP_000537
          Length = 393

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RRLILTIIT 9
           RR ILTIIT
Sbjct: 248 RRPILTIIT 256





>NP_001263689
          Length = 354

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RRLILTIIT 9
           RR ILTIIT
Sbjct: 209 RRPILTIIT 217





>NP_001119584
          Length = 393

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RRLILTIIT 9
           RR ILTIIT
Sbjct: 248 RRPILTIIT 256





>NP_001119586
          Length = 341

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RRLILTIIT 9
           RR ILTIIT
Sbjct: 248 RRPILTIIT 256





>NP_001263625
          Length = 302

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RRLILTIIT 9
           RR ILTIIT
Sbjct: 209 RRPILTIIT 217





>NP_001119590
          Length = 354

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RRLILTIIT 9
           RR ILTIIT
Sbjct: 209 RRPILTIIT 217





>NP_001263690
          Length = 354

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RRLILTIIT 9
           RR ILTIIT
Sbjct: 209 RRPILTIIT 217





>NP_001119585
          Length = 346

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RRLILTIIT 9
           RR ILTIIT
Sbjct: 248 RRPILTIIT 256





>NP_001263624
          Length = 307

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RRLILTIIT 9
           RR ILTIIT
Sbjct: 209 RRPILTIIT 217





>NP_001119588
          Length = 209

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RRLILTIIT 9
           RR ILTIIT
Sbjct: 116 RRPILTIIT 124





>NP_001119587
          Length = 261

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RRLILTIIT 9
           RR ILTIIT
Sbjct: 116 RRPILTIIT 124





>NP_001119589
          Length = 214

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RRLILTIIT 9
           RR ILTIIT
Sbjct: 116 RRPILTIIT 124





>NP_001263627
          Length = 182

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  RRLILTIIT 9
          RR ILTIIT
Sbjct: 89 RRPILTIIT 97





>NP_001263628
          Length = 187

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  RRLILTIIT 9
          RR ILTIIT
Sbjct: 89 RRPILTIIT 97





>NP_001263626
          Length = 234

 Score = 17.3 bits (33), Expect =  2528
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  RRLILTIIT 9
          RR ILTIIT
Sbjct: 89 RRPILTIIT 97





>NP_071940
          Length = 938

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   RRLILTIIT 9
           RR++LT+++
Sbjct: 212 RRILLTLVS 220





>XP_005268066
          Length = 1172

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   RRLILTIIT 9
           RR++LT+++
Sbjct: 446 RRILLTLVS 454





>NP_775924
          Length = 645

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  LILTIIT 9
          LILTI+T
Sbjct: 31 LILTILT 37





>NP_848599
          Length = 3092

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    RRLILTII 8
            RRL+LT++
Sbjct: 2719 RRLLLTML 2726





>NP_005952
          Length = 2439

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    RRLILTI 7
            RRL+LT+
Sbjct: 2418 RRLVLTL 2424





>XP_006713081
          Length = 3964

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    RRLILTII 8
            RRL+LT++
Sbjct: 3591 RRLLLTML 3598





>NP_112208
          Length = 321

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  LILTIIT 9
          LI+TIIT
Sbjct: 42 LIITIIT 48





  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.352    0.163    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 381,772
Number of extensions: 621
Number of successful extensions: 22
Number of sequences better than 10000.0: 22
Number of HSP's gapped: 22
Number of HSP's successfully gapped: 22
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.8 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package