Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000236                                                              21     229
NP_001120972                                                           21     229
XP_006716052                                                           21     229
XP_006716051                                                           21     229
NP_892006                                                              17    4312
NP_149062                                                              17    4312
XP_006715488                                                           17    4312
XP_006715487                                                           17    4312
XP_006715486                                                           17    4312
XP_006715485                                                           17    4312
XP_006715484                                                           17    4312
XP_006715483                                                           17    4312
XP_006715482                                                           17    4312
XP_006715481                                                           17    4312
XP_006715480                                                           17    4312
XP_006715479                                                           17    4312
XP_006715478                                                           17    4312
XP_006715477                                                           17    4312
XP_006715476                                                           17    4312
XP_006715475                                                           17    4312
XP_006715474                                                           17    4312
XP_006715473                                                           17    4312
XP_006715472                                                           17    4312
XP_006715471                                                           17    4312
XP_006715470                                                           17    4312
NP_001229679                                                           17    4312
NP_001277141                                                           16    5631
NP_114151                                                              16    5631
NP_076985                                                              16    7355
NP_067018                                                              16    7355
NP_066192                                                              16    7355
NP_777576                                                              16    7355
XP_005266250                                                           16    7355
NP_001248357                                                           15    9605
NP_663731                                                              15    9605
NP_001248356                                                           15    9605
NP_077320                                                              15    9605
NP_775110                                                              15    9605
NP_000061                                                              15    9605
NP_001167560                                                           15    9605
NP_114423                                                              15    9605
NP_001167561                                                           15    9605
NP_060681                                                              15    9605
NP_061950                                                              15    9605
NP_061949                                                              15    9605
NP_066307                                                              15    9605
XP_005260914                                                           15    9605
XP_005260913                                                           15    9605
XP_006715623                                                           15    9605
XP_006715622                                                           15    9605
XP_005267190                                                           15    9605
XP_005267189                                                           15    9605
XP_005267187                                                           15    9605
XP_005267185                                                           15    9605
XP_005267184                                                           15    9605
XP_006711938                                                           15    9605
XP_006711937                                                           15    9605
XP_006711936                                                           15    9605
XP_006711935                                                           15    9605
XP_006711934                                                           15    9605
XP_006711933                                                           15    9605
XP_006711932                                                           15    9605
XP_006710801                                                           15    9605
NP_009055                                                              15    9605
>NP_000236
          Length = 1390

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   RQLGASLND 9
           RQ+GASLND
Sbjct: 331 RQIGASLND 339
>NP_001120972
          Length = 1408

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   RQLGASLND 9
           RQ+GASLND
Sbjct: 331 RQIGASLND 339
>XP_006716052
          Length = 1409

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   RQLGASLND 9
           RQ+GASLND
Sbjct: 350 RQIGASLND 358
>XP_006716051
          Length = 1427

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   RQLGASLND 9
           RQ+GASLND
Sbjct: 350 RQIGASLND 358
>NP_892006
          Length = 8797

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RQLGASLND 9
            RQLG +L+D
Sbjct: 8336 RQLGKALDD 8344
>NP_149062
          Length = 8749

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RQLGASLND 9
            RQLG +L+D
Sbjct: 8288 RQLGKALDD 8296
>XP_006715488
          Length = 8721

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RQLGASLND 9
            RQLG +L+D
Sbjct: 8348 RQLGKALDD 8356
>XP_006715487
          Length = 8744

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RQLGASLND 9
            RQLG +L+D
Sbjct: 8371 RQLGKALDD 8379
>XP_006715486
          Length = 8758

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RQLGASLND 9
            RQLG +L+D
Sbjct: 8371 RQLGKALDD 8379
>XP_006715485
          Length = 8793

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RQLGASLND 9
            RQLG +L+D
Sbjct: 8318 RQLGKALDD 8326
>XP_006715484
          Length = 8794

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RQLGASLND 9
            RQLG +L+D
Sbjct: 8319 RQLGKALDD 8327
>XP_006715483
          Length = 8795

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RQLGASLND 9
            RQLG +L+D
Sbjct: 8320 RQLGKALDD 8328
>XP_006715482
          Length = 8797

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RQLGASLND 9
            RQLG +L+D
Sbjct: 8336 RQLGKALDD 8344
>XP_006715481
          Length = 8799

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RQLGASLND 9
            RQLG +L+D
Sbjct: 8324 RQLGKALDD 8332
>XP_006715480
          Length = 8799

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RQLGASLND 9
            RQLG +L+D
Sbjct: 8324 RQLGKALDD 8332
>XP_006715479
          Length = 8804

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RQLGASLND 9
            RQLG +L+D
Sbjct: 8343 RQLGKALDD 8351
>XP_006715478
          Length = 8809

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RQLGASLND 9
            RQLG +L+D
Sbjct: 8348 RQLGKALDD 8356
>XP_006715477
          Length = 8822

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RQLGASLND 9
            RQLG +L+D
Sbjct: 8347 RQLGKALDD 8355
>XP_006715476
          Length = 8823

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RQLGASLND 9
            RQLG +L+D
Sbjct: 8348 RQLGKALDD 8356
>XP_006715475
          Length = 8827

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RQLGASLND 9
            RQLG +L+D
Sbjct: 8366 RQLGKALDD 8374
>XP_006715474
          Length = 8829

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RQLGASLND 9
            RQLG +L+D
Sbjct: 8354 RQLGKALDD 8362
>XP_006715473
          Length = 8832

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RQLGASLND 9
            RQLG +L+D
Sbjct: 8371 RQLGKALDD 8379
>XP_006715472
          Length = 8839

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RQLGASLND 9
            RQLG +L+D
Sbjct: 8364 RQLGKALDD 8372
>XP_006715471
          Length = 8842

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RQLGASLND 9
            RQLG +L+D
Sbjct: 8367 RQLGKALDD 8375
>XP_006715470
          Length = 8846

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    RQLGASLND 9
            RQLG +L+D
Sbjct: 8371 RQLGKALDD 8379
>NP_001229679
          Length = 245

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  QLGASLND 9
          +LGA LND
Sbjct: 87 KLGAELND 94
>NP_001277141
          Length = 393

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RQLGASLND 9
           R+ GAS+ND
Sbjct: 286 REDGASVND 294
>NP_114151
          Length = 355

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RQLGASLND 9
           R+ GAS+ND
Sbjct: 248 REDGASVND 256
>NP_076985
          Length = 1104

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    RQLGASLND 9
            RQL   LND
Sbjct: 1083 RQLDTKLND 1091
>NP_067018
          Length = 220

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RQLGASL 7
           R+LGASL
Sbjct: 158 RELGASL 164
>NP_066192
          Length = 217

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RQLGASL 7
           R+LGASL
Sbjct: 158 RELGASL 164
>NP_777576
          Length = 1749

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QLGASLND 9
           Q+GASL D
Sbjct: 696 QIGASLMD 703
>XP_005266250
          Length = 125

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  RQLGASLND 9
          RQ G+SL+D
Sbjct: 24 RQPGSSLSD 32
>NP_001248357
          Length = 975

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RQLGASLN 8
           +Q+G SLN
Sbjct: 894 KQVGVSLN 901
>NP_663731
          Length = 890

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RQLGASLN 8
           +Q+G SLN
Sbjct: 809 KQVGVSLN 816
>NP_001248356
          Length = 896

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RQLGASLN 8
           +Q+G SLN
Sbjct: 815 KQVGVSLN 822
>NP_077320
          Length = 815

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RQLGASL 7
           R+LGASL
Sbjct: 493 RKLGASL 499
>NP_775110
          Length = 729

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RQLGASL 7
           R+LGASL
Sbjct: 445 RKLGASL 451
>NP_000061
          Length = 821

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RQLGASL 7
           R+LGASL
Sbjct: 493 RKLGASL 499
>NP_001167560
          Length = 875

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LGASLN 8
           LGASLN
Sbjct: 524 LGASLN 529
>NP_114423
          Length = 891

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LGASLN 8
           LGASLN
Sbjct: 540 LGASLN 545
>NP_001167561
          Length = 918

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LGASLN 8
           LGASLN
Sbjct: 567 LGASLN 572
>NP_060681
          Length = 678

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   RQLGAS 6
           RQLGAS
Sbjct: 206 RQLGAS 211
>NP_061950
          Length = 530

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  QLGASLN 8
          QLG SLN
Sbjct: 65 QLGRSLN 71
>NP_061949
          Length = 530

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  QLGASLN 8
          QLG SLN
Sbjct: 65 QLGKSLN 71
>NP_066307
          Length = 530

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2  QLGASLN 8
          QLG SLN
Sbjct: 65 QLGRSLN 71
>XP_005260914
          Length = 856

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LGASLN 8
           LGASLN
Sbjct: 505 LGASLN 510
>XP_005260913
          Length = 998

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LGASLN 8
           LGASLN
Sbjct: 647 LGASLN 652
>XP_006715623
          Length = 957

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RQLGASLND 9
           RQLG  L+D
Sbjct: 513 RQLGLLLHD 521
>XP_006715622
          Length = 2499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    RQLGASLND 9
            RQLG  L+D
Sbjct: 2055 RQLGLLLHD 2063
>XP_005267190
          Length = 3424

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    RQLGASLND 9
            RQLG  L+D
Sbjct: 2980 RQLGLLLHD 2988
>XP_005267189
          Length = 3425

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    RQLGASLND 9
            RQLG  L+D
Sbjct: 2994 RQLGLLLHD 3002
>XP_005267187
          Length = 3433

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    RQLGASLND 9
            RQLG  L+D
Sbjct: 2989 RQLGLLLHD 2997
>XP_005267185
          Length = 3437

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    RQLGASLND 9
            RQLG  L+D
Sbjct: 2993 RQLGLLLHD 3001
>XP_005267184
          Length = 3438

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    RQLGASLND 9
            RQLG  L+D
Sbjct: 2994 RQLGLLLHD 3002
>XP_006711938
          Length = 896

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RQLGASLN 8
           +Q+G SLN
Sbjct: 815 KQVGVSLN 822
>XP_006711937
          Length = 926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RQLGASLN 8
           +Q+G SLN
Sbjct: 845 KQVGVSLN 852
>XP_006711936
          Length = 926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RQLGASLN 8
           +Q+G SLN
Sbjct: 845 KQVGVSLN 852
>XP_006711935
          Length = 926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RQLGASLN 8
           +Q+G SLN
Sbjct: 845 KQVGVSLN 852
>XP_006711934
          Length = 926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RQLGASLN 8
           +Q+G SLN
Sbjct: 845 KQVGVSLN 852
>XP_006711933
          Length = 932

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RQLGASLN 8
           +Q+G SLN
Sbjct: 851 KQVGVSLN 858
>XP_006711932
          Length = 939

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RQLGASLN 8
           +Q+G SLN
Sbjct: 858 KQVGVSLN 865
>XP_006710801
          Length = 647

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   RQLGAS 6
           RQLGAS
Sbjct: 162 RQLGAS 167
>NP_009055
          Length = 3433

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    RQLGASLND 9
            RQLG  L+D
Sbjct: 2989 RQLGLLLHD 2997
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.311    0.130    0.341 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 443,111
Number of extensions: 826
Number of successful extensions: 64
Number of sequences better than 10000.0: 64
Number of HSP's gapped: 64
Number of HSP's successfully gapped: 64
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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