Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_444256                                                              18    1482
NP_444254                                                              18    1482
NP_444253                                                              18    1482
NP_444255                                                              18    1482
XP_005247551                                                           18    1482
XP_005247550                                                           18    1482
XP_006713712                                                           18    1482
XP_005247549                                                           18    1482
>NP_444256
          Length = 1794

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RLSSMVMIS 9
            RLSSM MIS
Sbjct: 1637 RLSSMAMIS 1645
>NP_444254
          Length = 1845

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RLSSMVMIS 9
            RLSSM MIS
Sbjct: 1688 RLSSMAMIS 1696
>NP_444253
          Length = 1914

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RLSSMVMIS 9
            RLSSM MIS
Sbjct: 1757 RLSSMAMIS 1765
>NP_444255
          Length = 1863

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RLSSMVMIS 9
            RLSSM MIS
Sbjct: 1706 RLSSMAMIS 1714
>XP_005247551
          Length = 1855

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RLSSMVMIS 9
            RLSSM MIS
Sbjct: 1698 RLSSMAMIS 1706
>XP_005247550
          Length = 1856

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RLSSMVMIS 9
            RLSSM MIS
Sbjct: 1699 RLSSMAMIS 1707
>XP_006713712
          Length = 1923

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RLSSMVMIS 9
            RLSSM MIS
Sbjct: 1767 RLSSMAMIS 1775
>XP_005247549
          Length = 1924

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RLSSMVMIS 9
            RLSSM MIS
Sbjct: 1767 RLSSMAMIS 1775
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.332    0.127    0.278 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 132,623
Number of extensions: 82
Number of successful extensions: 8
Number of sequences better than 10000.0: 8
Number of HSP's gapped: 8
Number of HSP's successfully gapped: 8
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package