Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              18    1482
NP_671714                                                              18    1482
XP_006715890                                                           18    1482
XP_005250160                                                           18    1482
XP_005250159                                                           18    1482
NP_055472                                                              17    3301
XP_005260678                                                           17    3301
NP_001123363                                                           16    5631
NP_694985                                                              16    7355
NP_006738                                                              16    7355
XP_005274246                                                           16    7355
NP_006355                                                              15    9605
XP_005267319                                                           15    9605
XP_006712935                                                           15    9605
XP_006712934                                                           15    9605
XP_006712933                                                           15    9605
NP_852118                                                              15    9605
>NP_005742
          Length = 3907

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    RLQAVSES 8
            RLQAVSES
Sbjct: 1371 RLQAVSES 1378
>NP_671714
          Length = 3899

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    RLQAVSES 8
            RLQAVSES
Sbjct: 1371 RLQAVSES 1378
>XP_006715890
          Length = 3860

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    RLQAVSES 8
            RLQAVSES
Sbjct: 1371 RLQAVSES 1378
>XP_005250160
          Length = 3939

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    RLQAVSES 8
            RLQAVSES
Sbjct: 1371 RLQAVSES 1378
>XP_005250159
          Length = 3952

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    RLQAVSES 8
            RLQAVSES
Sbjct: 1371 RLQAVSES 1378
>NP_055472
          Length = 1089

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1  RLQAVSES 8
          RLQAVS+S
Sbjct: 36 RLQAVSDS 43
>XP_005260678
          Length = 1089

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1  RLQAVSES 8
          RLQAVS+S
Sbjct: 36 RLQAVSDS 43
>NP_001123363
          Length = 535

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RLQAVSESM 9
           RLQ+V ES+
Sbjct: 415 RLQSVEESL 423
>NP_694985
          Length = 1042

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    RLQAVSES 8
            RLQA SES
Sbjct: 1015 RLQAESES 1022
>NP_006738
          Length = 1042

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    RLQAVSES 8
            RLQA SES
Sbjct: 1015 RLQAESES 1022
>XP_005274246
          Length = 1042

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    RLQAVSES 8
            RLQA SES
Sbjct: 1015 RLQAESES 1022
>NP_006355
          Length = 765

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LQAVSESM 9
           LQA+ ESM
Sbjct: 144 LQALKESM 151
>XP_005267319
          Length = 789

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LQAVSESM 9
           LQA+ ESM
Sbjct: 144 LQALKESM 151
>XP_006712935
          Length = 977

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LQAVSESM 9
           LQAV ES+
Sbjct: 786 LQAVGESL 793
>XP_006712934
          Length = 1583

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LQAVSESM 9
           LQAV ES+
Sbjct: 682 LQAVGESL 689
>XP_006712933
          Length = 1687

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LQAVSESM 9
           LQAV ES+
Sbjct: 786 LQAVGESL 793
>NP_852118
          Length = 1684

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LQAVSESM 9
           LQAV ES+
Sbjct: 783 LQAVGESL 790
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.309    0.112    0.245 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 239,941
Number of extensions: 313
Number of successful extensions: 17
Number of sequences better than 10000.0: 17
Number of HSP's gapped: 17
Number of HSP's successfully gapped: 17
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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