Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000537                                                              17    3301
NP_001263689                                                           17    3301
NP_001119584                                                           17    3301
NP_001119586                                                           17    3301
NP_001263625                                                           17    3301
NP_001119590                                                           17    3301
NP_001263690                                                           17    3301
NP_001119585                                                           17    3301
NP_001263624                                                           17    3301
NP_001119588                                                           17    3301
NP_001119587                                                           17    3301
NP_001119589                                                           17    3301
NP_001263627                                                           17    3301
NP_001263628                                                           17    3301
NP_001263626                                                           17    3301
XP_005276382                                                           17    4312
XP_006725162                                                           17    4312
XP_005251181                                                           17    4312
XP_005276079                                                           17    4312
NP_775924                                                              16    5631
NP_112208                                                              16    7355
NP_062873                                                              15    9605
NP_062874                                                              15    9605
NP_000863                                                              15    9605
>NP_000537
          Length = 393

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RLILTIITL 9
           R ILTIITL
Sbjct: 249 RPILTIITL 257
>NP_001263689
          Length = 354

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RLILTIITL 9
           R ILTIITL
Sbjct: 210 RPILTIITL 218
>NP_001119584
          Length = 393

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RLILTIITL 9
           R ILTIITL
Sbjct: 249 RPILTIITL 257
>NP_001119586
          Length = 341

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RLILTIITL 9
           R ILTIITL
Sbjct: 249 RPILTIITL 257
>NP_001263625
          Length = 302

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RLILTIITL 9
           R ILTIITL
Sbjct: 210 RPILTIITL 218
>NP_001119590
          Length = 354

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RLILTIITL 9
           R ILTIITL
Sbjct: 210 RPILTIITL 218
>NP_001263690
          Length = 354

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RLILTIITL 9
           R ILTIITL
Sbjct: 210 RPILTIITL 218
>NP_001119585
          Length = 346

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RLILTIITL 9
           R ILTIITL
Sbjct: 249 RPILTIITL 257
>NP_001263624
          Length = 307

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RLILTIITL 9
           R ILTIITL
Sbjct: 210 RPILTIITL 218
>NP_001119588
          Length = 209

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RLILTIITL 9
           R ILTIITL
Sbjct: 117 RPILTIITL 125
>NP_001119587
          Length = 261

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RLILTIITL 9
           R ILTIITL
Sbjct: 117 RPILTIITL 125
>NP_001119589
          Length = 214

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RLILTIITL 9
           R ILTIITL
Sbjct: 117 RPILTIITL 125
>NP_001263627
          Length = 182

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  RLILTIITL 9
          R ILTIITL
Sbjct: 90 RPILTIITL 98
>NP_001263628
          Length = 187

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  RLILTIITL 9
          R ILTIITL
Sbjct: 90 RPILTIITL 98
>NP_001263626
          Length = 234

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  RLILTIITL 9
          R ILTIITL
Sbjct: 90 RPILTIITL 98
>XP_005276382
          Length = 138

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  RLILTIITL 9
          RL+LT+ TL
Sbjct: 3  RLVLTLCTL 11
>XP_006725162
          Length = 138

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  RLILTIITL 9
          RL+LT+ TL
Sbjct: 3  RLVLTLCTL 11
>XP_005251181
          Length = 138

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  RLILTIITL 9
          RL+LT+ TL
Sbjct: 3  RLVLTLCTL 11
>XP_005276079
          Length = 138

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  RLILTIITL 9
          RL+LT+ TL
Sbjct: 3  RLVLTLCTL 11
>NP_775924
          Length = 645

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  LILTIITL 9
          LILTI+T+
Sbjct: 31 LILTILTI 38
>NP_112208
          Length = 321

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  LILTIITL 9
          LI+TIIT+
Sbjct: 42 LIITIITV 49
>NP_062873
          Length = 479

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  ILTIITL 9
          ILT+ITL
Sbjct: 87 ILTLITL 93
>NP_062874
          Length = 432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  ILTIITL 9
          ILT+ITL
Sbjct: 87 ILTLITL 93
>NP_000863
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  ILTIITL 9
          ILT+ITL
Sbjct: 87 ILTLITL 93
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.351    0.166    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 364,510
Number of extensions: 546
Number of successful extensions: 24
Number of sequences better than 10000.0: 24
Number of HSP's gapped: 24
Number of HSP's successfully gapped: 24
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.7 bits)
S2: 28 (15.4 bits)

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