Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005148                                                              19     665
NP_009297                                                              19     665
NP_001165375                                                           16    5631
NP_055518                                                              16    5631
XP_005276812                                                           16    5631
XP_006713491                                                           16    5631
XP_005276811                                                           16    5631
XP_006713490                                                           16    5631
XP_005276810                                                           16    5631
XP_005276809                                                           16    5631
XP_006713489                                                           16    5631
XP_005276808                                                           16    5631
NP_001238892                                                           15    9605
NP_003172                                                              15    9605
NP_001257413                                                           15    9605
NP_001238891                                                           15    9605
NP_056410                                                              15    9605
NP_004904                                                              15    9605
XP_006725061                                                           15    9605
XP_006721413                                                           15    9605
XP_005256386                                                           15    9605
>NP_005148
          Length = 1130

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    RIANGAITK 9
            RIA+GAITK
Sbjct: 1021 RIASGAITK 1029
>NP_009297
          Length = 1149

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    RIANGAITK 9
            RIA+GAITK
Sbjct: 1040 RIASGAITK 1048
>NP_001165375
          Length = 1506

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RIANGAITK 9
           RIANG  T+
Sbjct: 903 RIANGIATR 911
>NP_055518
          Length = 1507

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RIANGAITK 9
           RIANG  T+
Sbjct: 904 RIANGIATR 912
>XP_005276812
          Length = 1507

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RIANGAITK 9
           RIANG  T+
Sbjct: 904 RIANGIATR 912
>XP_006713491
          Length = 1425

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RIANGAITK 9
           RIANG  T+
Sbjct: 822 RIANGIATR 830
>XP_005276811
          Length = 1507

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RIANGAITK 9
           RIANG  T+
Sbjct: 904 RIANGIATR 912
>XP_006713490
          Length = 1507

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RIANGAITK 9
           RIANG  T+
Sbjct: 904 RIANGIATR 912
>XP_005276810
          Length = 1507

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RIANGAITK 9
           RIANG  T+
Sbjct: 904 RIANGIATR 912
>XP_005276809
          Length = 1507

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RIANGAITK 9
           RIANG  T+
Sbjct: 904 RIANGIATR 912
>XP_006713489
          Length = 1507

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RIANGAITK 9
           RIANG  T+
Sbjct: 904 RIANGIATR 912
>XP_005276808
          Length = 1507

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RIANGAITK 9
           RIANG  T+
Sbjct: 904 RIANGIATR 912
>NP_001238892
          Length = 791

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   ANGAIT 8
           ANGA+T
Sbjct: 129 ANGAVT 134
>NP_003172
          Length = 435

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   IANGAIT 8
           ++NGA+T
Sbjct: 353 VSNGAVT 359
>NP_001257413
          Length = 377

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   IANGAIT 8
           ++NGA+T
Sbjct: 295 VSNGAVT 301
>NP_001238891
          Length = 871

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   ANGAIT 8
           ANGA+T
Sbjct: 129 ANGAVT 134
>NP_056410
          Length = 871

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   ANGAIT 8
           ANGA+T
Sbjct: 129 ANGAVT 134
>NP_004904
          Length = 631

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  RIANGAI 7
          ++ANGAI
Sbjct: 18 KLANGAI 24
>XP_006725061
          Length = 904

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   ANGAIT 8
           ANGA+T
Sbjct: 129 ANGAVT 134
>XP_006721413
          Length = 597

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  RIANGAI 7
          ++ANGAI
Sbjct: 18 KLANGAI 24
>XP_005256386
          Length = 632

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  RIANGAI 7
          ++ANGAI
Sbjct: 18 KLANGAI 24
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.318    0.131    0.343 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 431,416
Number of extensions: 355
Number of successful extensions: 21
Number of sequences better than 10000.0: 21
Number of HSP's gapped: 21
Number of HSP's successfully gapped: 21
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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