Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_733751                                                              19     665
XP_006716142                                                           19     665
XP_005250088                                                           19     665
XP_006716141                                                           19     665
XP_005250085                                                           19     665
XP_006716140                                                           19     665
XP_005250084                                                           19     665
XP_005250083                                                           19     665
XP_005250082                                                           19     665
XP_006715411                                                           17    2528
NP_542781                                                              17    2528
NP_003473                                                              17    3301
XP_006719679                                                           17    3301
XP_005269219                                                           17    3301
XP_006719678                                                           17    3301
XP_006719677                                                           17    3301
NP_005617                                                              17    4312
XP_006710879                                                           17    4312
XP_006710878                                                           17    4312
NP_612395                                                              16    5631
NP_001122403                                                           16    5631
XP_006714477                                                           16    5631
NP_955352                                                              16    7355
NP_001274371                                                           16    7355
NP_001274368                                                           16    7355
NP_001274372                                                           16    7355
NP_001274366                                                           16    7355
NP_001274369                                                           16    7355
NP_004594                                                              16    7355
NP_689706                                                              16    7355
NP_001159375                                                           16    7355
XP_005250609                                                           16    7355
XP_005263289                                                           16    7355
XP_006714373                                                           16    7355
XP_005263286                                                           16    7355
XP_005270565                                                           16    7355
XP_005270564                                                           16    7355
NP_008996                                                              15    9605
NP_055062                                                              15    9605
NP_001258867                                                           15    9605
NP_631896                                                              15    9605
NP_005409                                                              15    9605
NP_998783                                                              15    9605
NP_001401                                                              15    9605
XP_005253141                                                           15    9605
XP_005253140                                                           15    9605
XP_005253138                                                           15    9605
XP_005253137                                                           15    9605
XP_005253136                                                           15    9605
XP_006718348                                                           15    9605
XP_006718347                                                           15    9605
XP_005253134                                                           15    9605
XP_006714485                                                           15    9605
XP_005263418                                                           15    9605
XP_005263417                                                           15    9605
XP_006714484                                                           15    9605
XP_005263416                                                           15    9605
XP_006714483                                                           15    9605
XP_005263415                                                           15    9605
>NP_733751
          Length = 4911

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   RGRSKLKS 8
           RGRSKLKS
Sbjct: 907 RGRSKLKS 914
>XP_006716142
          Length = 4927

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   RGRSKLKS 8
           RGRSKLKS
Sbjct: 908 RGRSKLKS 915
>XP_005250088
          Length = 4928

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   RGRSKLKS 8
           RGRSKLKS
Sbjct: 908 RGRSKLKS 915
>XP_006716141
          Length = 4959

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   RGRSKLKS 8
           RGRSKLKS
Sbjct: 908 RGRSKLKS 915
>XP_005250085
          Length = 4979

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   RGRSKLKS 8
           RGRSKLKS
Sbjct: 908 RGRSKLKS 915
>XP_006716140
          Length = 4982

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   RGRSKLKS 8
           RGRSKLKS
Sbjct: 908 RGRSKLKS 915
>XP_005250084
          Length = 4982

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   RGRSKLKS 8
           RGRSKLKS
Sbjct: 908 RGRSKLKS 915
>XP_005250083
          Length = 4982

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   RGRSKLKS 8
           RGRSKLKS
Sbjct: 907 RGRSKLKS 914
>XP_005250082
          Length = 4983

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   RGRSKLKS 8
           RGRSKLKS
Sbjct: 908 RGRSKLKS 915
>XP_006715411
          Length = 166

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  RGRSKLKSL 9
          RGRS+ KSL
Sbjct: 82 RGRSRSKSL 90
>NP_542781
          Length = 261

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RGRSKLKSL 9
           RGRS+ KSL
Sbjct: 177 RGRSRSKSL 185
>NP_003473
          Length = 5537

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    RGRSKLKS 8
            RGR++LKS
Sbjct: 1324 RGRARLKS 1331
>XP_006719679
          Length = 5536

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    RGRSKLKS 8
            RGR++LKS
Sbjct: 1324 RGRARLKS 1331
>XP_005269219
          Length = 5537

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    RGRSKLKS 8
            RGR++LKS
Sbjct: 1324 RGRARLKS 1331
>XP_006719678
          Length = 5539

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    RGRSKLKS 8
            RGR++LKS
Sbjct: 1324 RGRARLKS 1331
>XP_006719677
          Length = 5540

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    RGRSKLKS 8
            RGR++LKS
Sbjct: 1324 RGRARLKS 1331
>NP_005617
          Length = 494

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RGRSKLKSL 9
           RGRS+ KSL
Sbjct: 319 RGRSQEKSL 327
>XP_006710879
          Length = 371

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RGRSKLKSL 9
           RGRS+ KSL
Sbjct: 196 RGRSQEKSL 204
>XP_006710878
          Length = 371

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   RGRSKLKSL 9
           RGRS+ KSL
Sbjct: 196 RGRSQEKSL 204
>NP_612395
          Length = 494

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RGRSKLKS 8
           +GR KLKS
Sbjct: 332 QGRKKLKS 339
>NP_001122403
          Length = 389

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RGRSKLKS 8
           +GR KLKS
Sbjct: 332 QGRKKLKS 339
>XP_006714477
          Length = 364

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RGRSKLKS 8
           +GR KLKS
Sbjct: 332 QGRKKLKS 339
>NP_955352
          Length = 842

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RGRSKLKS 8
           R +SKLKS
Sbjct: 789 RAKSKLKS 796
>NP_001274371
          Length = 842

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RGRSKLKS 8
           R +SKLKS
Sbjct: 789 RAKSKLKS 796
>NP_001274368
          Length = 842

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RGRSKLKS 8
           R +SKLKS
Sbjct: 789 RAKSKLKS 796
>NP_001274372
          Length = 842

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RGRSKLKS 8
           R +SKLKS
Sbjct: 789 RAKSKLKS 796
>NP_001274366
          Length = 830

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RGRSKLKS 8
           R +SKLKS
Sbjct: 777 RAKSKLKS 784
>NP_001274369
          Length = 842

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RGRSKLKS 8
           R +SKLKS
Sbjct: 789 RAKSKLKS 796
>NP_004594
          Length = 288

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  RSKLKSL 9
          RSKLKS+
Sbjct: 90 RSKLKSI 96
>NP_689706
          Length = 420

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RGRSKLKS 8
           RGR K+K+
Sbjct: 192 RGRKKIKA 199
>NP_001159375
          Length = 251

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  RSKLKSL 9
          RSKLKS+
Sbjct: 90 RSKLKSI 96
>XP_005250609
          Length = 280

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  RSKLKSL 9
          RSKLKS+
Sbjct: 90 RSKLKSI 96
>XP_005263289
          Length = 842

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RGRSKLKS 8
           R +SKLKS
Sbjct: 789 RAKSKLKS 796
>XP_006714373
          Length = 857

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RGRSKLKS 8
           R +SKLKS
Sbjct: 804 RAKSKLKS 811
>XP_005263286
          Length = 869

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RGRSKLKS 8
           R +SKLKS
Sbjct: 816 RAKSKLKS 823
>XP_005270565
          Length = 407

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RGRSKLKS 8
           RGR K+K+
Sbjct: 179 RGRKKIKA 186
>XP_005270564
          Length = 407

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RGRSKLKS 8
           RGR K+K+
Sbjct: 179 RGRKKIKA 186
>NP_008996
          Length = 378

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RGRSKLK 7
           RGR+KL+
Sbjct: 264 RGRAKLR 270
>NP_055062
          Length = 1499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GRSKLKSL 9
           GR+KLK +
Sbjct: 529 GRNKLKKI 536
>NP_001258867
          Length = 2845

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   RGRSKLKS 8
           RGR  LKS
Sbjct: 935 RGRGALKS 942
>NP_631896
          Length = 717

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RGRSKLKSL 9
           RG+ +LK L
Sbjct: 208 RGKKRLKKL 216
>NP_005409
          Length = 1137

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RGRSKLKSL 9
           RG+ +LK L
Sbjct: 628 RGKKRLKKL 636
>NP_998783
          Length = 1137

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RGRSKLKSL 9
           RG+ +LK L
Sbjct: 628 RGKKRLKKL 636
>NP_001401
          Length = 2778

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   RGRSKLKS 8
           RGR  LKS
Sbjct: 868 RGRGALKS 875
>XP_005253141
          Length = 717

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RGRSKLKSL 9
           RG+ +LK L
Sbjct: 208 RGKKRLKKL 216
>XP_005253140
          Length = 717

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RGRSKLKSL 9
           RG+ +LK L
Sbjct: 208 RGKKRLKKL 216
>XP_005253138
          Length = 850

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RGRSKLKSL 9
           RG+ +LK L
Sbjct: 658 RGKKRLKKL 666
>XP_005253137
          Length = 1137

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RGRSKLKSL 9
           RG+ +LK L
Sbjct: 628 RGKKRLKKL 636
>XP_005253136
          Length = 1137

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RGRSKLKSL 9
           RG+ +LK L
Sbjct: 628 RGKKRLKKL 636
>XP_006718348
          Length = 1137

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RGRSKLKSL 9
           RG+ +LK L
Sbjct: 628 RGKKRLKKL 636
>XP_006718347
          Length = 1137

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RGRSKLKSL 9
           RG+ +LK L
Sbjct: 628 RGKKRLKKL 636
>XP_005253134
          Length = 1167

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RGRSKLKSL 9
           RG+ +LK L
Sbjct: 658 RGKKRLKKL 666
>XP_006714485
          Length = 1585

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GRSKLKSL 9
           GR+KLK +
Sbjct: 574 GRNKLKKI 581
>XP_005263418
          Length = 1654

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GRSKLKSL 9
           GR+KLK +
Sbjct: 684 GRNKLKKI 691
>XP_005263417
          Length = 1660

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GRSKLKSL 9
           GR+KLK +
Sbjct: 690 GRNKLKKI 697
>XP_006714484
          Length = 1685

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GRSKLKSL 9
           GR+KLK +
Sbjct: 690 GRNKLKKI 697
>XP_005263416
          Length = 1693

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GRSKLKSL 9
           GR+KLK +
Sbjct: 690 GRNKLKKI 697
>XP_006714483
          Length = 1695

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GRSKLKSL 9
           GR+KLK +
Sbjct: 684 GRNKLKKI 691
>XP_005263415
          Length = 1701

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GRSKLKSL 9
           GR+KLK +
Sbjct: 690 GRNKLKKI 697
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.314    0.130    0.325 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 432,782
Number of extensions: 486
Number of successful extensions: 59
Number of sequences better than 10000.0: 59
Number of HSP's gapped: 59
Number of HSP's successfully gapped: 59
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package