Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000258                                                              20     390
NP_001035957                                                           20     390
XP_006721991                                                           20     390
XP_006721990                                                           20     390
XP_006721989                                                           20     390
XP_005258041                                                           20     390
XP_006721988                                                           20     390
XP_006721987                                                           20     390
XP_006721986                                                           20     390
XP_005258040                                                           20     390
XP_006721985                                                           20     390
NP_001243199                                                           17    2528
NP_015556                                                              17    2528
NP_001243198                                                           17    2528
NP_005836                                                              17    4312
NP_113620                                                              17    4312
NP_001129426                                                           17    4312
NP_001248379                                                           17    4312
NP_001248380                                                           17    4312
XP_005254082                                                           17    4312
XP_006719977                                                           17    4312
XP_005272282                                                           17    4312
XP_005272281                                                           17    4312
NP_002232                                                              16    7355
NP_006280                                                              16    7355
NP_055872                                                              16    7355
NP_001258733                                                           16    7355
NP_002616                                                              16    7355
NP_659444                                                              16    7355
NP_008890                                                              16    7355
NP_001258734                                                           16    7355
XP_005262071                                                           16    7355
XP_006723416                                                           16    7355
XP_006723415                                                           16    7355
XP_006723414                                                           16    7355
XP_005258689                                                           16    7355
XP_006719852                                                           16    7355
XP_005266357                                                           16    7355
XP_006719851                                                           16    7355
XP_006719850                                                           16    7355
XP_006719849                                                           16    7355
XP_006719848                                                           16    7355
XP_005266356                                                           16    7355
XP_006719847                                                           16    7355
XP_006719846                                                           16    7355
XP_006719845                                                           16    7355
XP_006719844                                                           16    7355
XP_006719843                                                           16    7355
XP_006719842                                                           16    7355
XP_005251759                                                           16    7355
XP_005251758                                                           16    7355
XP_006716915                                                           16    7355
XP_005251621                                                           16    7355
NP_689633                                                              16    7355
NP_001138985                                                           15    9605
NP_055581                                                              15    9605
NP_066268                                                              15    9605
NP_001138944                                                           15    9605
NP_115635                                                              15    9605
NP_001138987                                                           15    9605
NP_001138986                                                           15    9605
NP_001138945                                                           15    9605
NP_653213                                                              15    9605
XP_006722454                                                           15    9605
XP_006722453                                                           15    9605
XP_006722452                                                           15    9605
XP_006722451                                                           15    9605
XP_006722450                                                           15    9605
XP_006722449                                                           15    9605
XP_006722448                                                           15    9605
XP_006722447                                                           15    9605
XP_006719238                                                           15    9605
XP_005249975                                                           15    9605
XP_006710296                                                           15    9605
NP_001166600                                                           15    9605
NP_056525                                                              15    9605
>NP_000258
          Length = 2818

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RFFLDTASD 9
            RFFLD ASD
Sbjct: 1456 RFFLDIASD 1464
>NP_001035957
          Length = 2839

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RFFLDTASD 9
            RFFLD ASD
Sbjct: 1477 RFFLDIASD 1485
>XP_006721991
          Length = 1632

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RFFLDTASD 9
            RFFLD ASD
Sbjct: 1487 RFFLDIASD 1495
>XP_006721990
          Length = 2823

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RFFLDTASD 9
            RFFLD ASD
Sbjct: 1487 RFFLDIASD 1495
>XP_006721989
          Length = 2823

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RFFLDTASD 9
            RFFLD ASD
Sbjct: 1487 RFFLDIASD 1495
>XP_005258041
          Length = 2836

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RFFLDTASD 9
            RFFLD ASD
Sbjct: 1456 RFFLDIASD 1464
>XP_006721988
          Length = 2846

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RFFLDTASD 9
            RFFLD ASD
Sbjct: 1466 RFFLDIASD 1474
>XP_006721987
          Length = 2849

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RFFLDTASD 9
            RFFLD ASD
Sbjct: 1487 RFFLDIASD 1495
>XP_006721986
          Length = 2854

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RFFLDTASD 9
            RFFLD ASD
Sbjct: 1474 RFFLDIASD 1482
>XP_005258040
          Length = 2857

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RFFLDTASD 9
            RFFLD ASD
Sbjct: 1477 RFFLDIASD 1485
>XP_006721985
          Length = 2867

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    RFFLDTASD 9
            RFFLD ASD
Sbjct: 1487 RFFLDIASD 1495
>NP_001243199
          Length = 597

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RFFLDTAS 8
           RF+LDT S
Sbjct: 282 RFYLDTVS 289
>NP_015556
          Length = 665

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RFFLDTAS 8
           RF+LDT S
Sbjct: 350 RFYLDTVS 357
>NP_001243198
          Length = 597

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RFFLDTAS 8
           RF+LDT S
Sbjct: 282 RFYLDTVS 289
>NP_005836
          Length = 1325

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RFFLDTASD 9
           R+FL+T+ D
Sbjct: 880 RYFLETSRD 888
>NP_113620
          Length = 277

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RFFLDTASD 9
           R F+DT SD
Sbjct: 155 RLFVDTDSD 163
>NP_001129426
          Length = 201

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RFFLDTASD 9
           R F+DT SD
Sbjct: 155 RLFVDTDSD 163
>NP_001248379
          Length = 268

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RFFLDTASD 9
           R F+DT SD
Sbjct: 146 RLFVDTDSD 154
>NP_001248380
          Length = 282

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RFFLDTASD 9
           R F+DT SD
Sbjct: 160 RLFVDTDSD 168
>XP_005254082
          Length = 1282

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RFFLDTASD 9
           R+FL+T+ D
Sbjct: 837 RYFLETSRD 845
>XP_006719977
          Length = 1295

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RFFLDTASD 9
           R+FL+T+ D
Sbjct: 850 RYFLETSRD 858
>XP_005272282
          Length = 254

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RFFLDTASD 9
           R F+DT SD
Sbjct: 132 RLFVDTDSD 140
>XP_005272281
          Length = 291

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   RFFLDTASD 9
           R F+DT SD
Sbjct: 169 RLFVDTDSD 177
>NP_002232
          Length = 379

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FFLDTASD 9
           F +DTASD
Sbjct: 238 FQVDTASD 245
>NP_006280
          Length = 2541

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    LDTASD 9
            LDTASD
Sbjct: 1152 LDTASD 1157
>NP_055872
          Length = 4678

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    FFLDTASD 9
            F L+TASD
Sbjct: 2119 FSLETASD 2126
>NP_001258733
          Length = 449

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   FFLDTASD 9
           +FLD +SD
Sbjct: 381 YFLDKSSD 388
>NP_002616
          Length = 471

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   FFLDTASD 9
           +FLD +SD
Sbjct: 403 YFLDKSSD 410
>NP_659444
          Length = 1033

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RFFLDTASD 9
           +FF D +SD
Sbjct: 119 KFFRDVSSD 127
>NP_008890
          Length = 662

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   RFFLDTAS 8
           +FF+DT++
Sbjct: 421 KFFMDTST 428
>NP_001258734
          Length = 406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   FFLDTASD 9
           +FLD +SD
Sbjct: 338 YFLDKSSD 345
>XP_005262071
          Length = 448

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   FFLDTASD 9
           +FLD +SD
Sbjct: 380 YFLDKSSD 387
>XP_006723416
          Length = 513

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   RFFLDTAS 8
           +FF+DT++
Sbjct: 272 KFFMDTST 279
>XP_006723415
          Length = 664

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   RFFLDTAS 8
           +FF+DT++
Sbjct: 423 KFFMDTST 430
>XP_006723414
          Length = 664

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   RFFLDTAS 8
           +FF+DT++
Sbjct: 423 KFFMDTST 430
>XP_005258689
          Length = 934

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  RFFLDTASD 9
          +FF D +SD
Sbjct: 20 KFFRDVSSD 28
>XP_006719852
          Length = 4752

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    FFLDTASD 9
            F L+TASD
Sbjct: 2119 FSLETASD 2126
>XP_005266357
          Length = 4600

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    FFLDTASD 9
            F L+TASD
Sbjct: 2119 FSLETASD 2126
>XP_006719851
          Length = 4689

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    FFLDTASD 9
            F L+TASD
Sbjct: 2119 FSLETASD 2126
>XP_006719850
          Length = 4697

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    FFLDTASD 9
            F L+TASD
Sbjct: 2119 FSLETASD 2126
>XP_006719849
          Length = 4703

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    FFLDTASD 9
            F L+TASD
Sbjct: 2119 FSLETASD 2126
>XP_006719848
          Length = 4737

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    FFLDTASD 9
            F L+TASD
Sbjct: 2119 FSLETASD 2126
>XP_005266356
          Length = 4755

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    FFLDTASD 9
            F L+TASD
Sbjct: 2119 FSLETASD 2126
>XP_006719847
          Length = 4761

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    FFLDTASD 9
            F L+TASD
Sbjct: 2083 FSLETASD 2090
>XP_006719846
          Length = 4763

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    FFLDTASD 9
            F L+TASD
Sbjct: 2119 FSLETASD 2126
>XP_006719845
          Length = 4772

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    FFLDTASD 9
            F L+TASD
Sbjct: 2119 FSLETASD 2126
>XP_006719844
          Length = 4789

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    FFLDTASD 9
            F L+TASD
Sbjct: 2119 FSLETASD 2126
>XP_006719843
          Length = 4794

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    FFLDTASD 9
            F L+TASD
Sbjct: 2119 FSLETASD 2126
>XP_006719842
          Length = 4797

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    FFLDTASD 9
            F L+TASD
Sbjct: 2119 FSLETASD 2126
>XP_005251759
          Length = 330

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   FFLDTA 7
           FF+DTA
Sbjct: 234 FFIDTA 239
>XP_005251758
          Length = 340

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   FFLDTA 7
           FF+DTA
Sbjct: 244 FFIDTA 249
>XP_006716915
          Length = 2542

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    LDTASD 9
            LDTASD
Sbjct: 1152 LDTASD 1157
>XP_005251621
          Length = 2542

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    LDTASD 9
            LDTASD
Sbjct: 1152 LDTASD 1157
>NP_689633
          Length = 409

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   FFLDTA 7
           FF+DTA
Sbjct: 313 FFIDTA 318
>NP_001138985
          Length = 414

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   FFLDTAS 8
           FFL TAS
Sbjct: 271 FFLTTAS 277
>NP_055581
          Length = 414

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   FFLDTAS 8
           FFL TAS
Sbjct: 271 FFLTTAS 277
>NP_066268
          Length = 354

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   RFFLDTA 7
           +FF+DT+
Sbjct: 258 KFFIDTS 264
>NP_001138944
          Length = 1114

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    RFFLDT 6
            RFFL+T
Sbjct: 1094 RFFLET 1099
>NP_115635
          Length = 790

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   RFFLDTA 7
           R+F+DTA
Sbjct: 410 RWFVDTA 416
>NP_001138987
          Length = 346

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   FFLDTAS 8
           FFL TAS
Sbjct: 203 FFLTTAS 209
>NP_001138986
          Length = 434

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   FFLDTAS 8
           FFL TAS
Sbjct: 291 FFLTTAS 297
>NP_001138945
          Length = 512

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   RFFLDT 6
           RFFL+T
Sbjct: 444 RFFLET 449
>NP_653213
          Length = 2211

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    RFFLDT 6
            RFFL+T
Sbjct: 2143 RFFLET 2148
>XP_006722454
          Length = 1144

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    RFFLDT 6
            RFFL+T
Sbjct: 1076 RFFLET 1081
>XP_006722453
          Length = 1162

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    RFFLDT 6
            RFFL+T
Sbjct: 1094 RFFLET 1099
>XP_006722452
          Length = 1162

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    RFFLDT 6
            RFFL+T
Sbjct: 1094 RFFLET 1099
>XP_006722451
          Length = 1206

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    RFFLDT 6
            RFFL+T
Sbjct: 1138 RFFLET 1143
>XP_006722450
          Length = 1249

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    RFFLDT 6
            RFFL+T
Sbjct: 1236 RFFLET 1241
>XP_006722449
          Length = 1256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    RFFLDT 6
            RFFL+T
Sbjct: 1236 RFFLET 1241
>XP_006722448
          Length = 1304

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    RFFLDT 6
            RFFL+T
Sbjct: 1236 RFFLET 1241
>XP_006722447
          Length = 1933

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    RFFLDT 6
            RFFL+T
Sbjct: 1865 RFFLET 1870
>XP_006719238
          Length = 141

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  RFFLDT 6
          +FFLDT
Sbjct: 45 QFFLDT 50
>XP_005249975
          Length = 414

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   FFLDTAS 8
           FFL TAS
Sbjct: 271 FFLTTAS 277
>XP_006710296
          Length = 141

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  RFFLDT 6
          +FFLDT
Sbjct: 45 QFFLDT 50
>NP_001166600
          Length = 457

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   RFFLDT 6
           RFFL+T
Sbjct: 444 RFFLET 449
>NP_056525
          Length = 478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  FFLDTAS 8
          FF+DT S
Sbjct: 87 FFVDTGS 93
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.335    0.143    0.421 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 392,581
Number of extensions: 493
Number of successful extensions: 76
Number of sequences better than 10000.0: 76
Number of HSP's gapped: 76
Number of HSP's successfully gapped: 76
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.3 bits)
S2: 28 (15.4 bits)

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