Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_115927                                                              20     509
NP_079410                                                              17    3301
NP_001004311                                                           17    3301
XP_005256233                                                           17    3301
XP_005256232                                                           17    3301
XP_005256231                                                           17    3301
XP_005256229                                                           17    3301
XP_005256228                                                           17    3301
XP_005256227                                                           17    3301
XP_006721346                                                           17    3301
XP_005256226                                                           17    3301
XP_006721345                                                           17    3301
XP_006721344                                                           17    3301
XP_006721343                                                           17    3301
XP_005256225                                                           17    3301
XP_006710237                                                           17    3301
NP_001234926                                                           17    4312
NP_002947                                                              17    4312
NP_065928                                                              17    4312
NP_937883                                                              17    4312
XP_005256527                                                           17    4312
XP_006719618                                                           17    4312
XP_006719617                                                           17    4312
XP_006719616                                                           17    4312
XP_006719615                                                           17    4312
XP_006719614                                                           17    4312
XP_005253652                                                           17    4312
XP_005253651                                                           17    4312
XP_005253650                                                           17    4312
NP_003615                                                              16    5631
NP_015561                                                              16    5631
NP_060050                                                              16    5631
NP_015559                                                              16    5631
NP_002263                                                              16    5631
XP_005259721                                                           16    5631
XP_005269983                                                           16    5631
XP_005269982                                                           16    5631
XP_006717970                                                           16    5631
NP_001263309                                                           16    7355
NP_057733                                                              16    7355
NP_659492                                                              16    7355
NP_001008240                                                           16    7355
NP_004632                                                              15    9605
NP_002462                                                              15    9605
NP_001182555                                                           15    9605
NP_006735                                                              15    9605
NP_000248                                                              15    9605
NP_065935                                                              15    9605
NP_064612                                                              15    9605
XP_005261469                                                           15    9605
XP_006723903                                                           15    9605
XP_006723902                                                           15    9605
XP_005256332                                                           15    9605
XP_005267754                                                           15    9605
XP_005267753                                                           15    9605
XP_005267752                                                           15    9605
XP_006720215                                                           15    9605
XP_006720214                                                           15    9605
XP_005267751                                                           15    9605
XP_005270080                                                           15    9605
XP_005252668                                                           15    9605
XP_006717572                                                           15    9605
XP_005252667                                                           15    9605
XP_005252666                                                           15    9605
XP_005252665                                                           15    9605
XP_005252663                                                           15    9605
XP_005252662                                                           15    9605
NP_848544                                                              15    9605
NP_055107                                                              15    9605
>NP_115927
          Length = 1321

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   RERVRLLNR 9
           RER RLLNR
Sbjct: 696 RERARLLNR 704
>NP_079410
          Length = 2881

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    ERVRLLNR 9
            ERV+L+NR
Sbjct: 2543 ERVQLINR 2550
>NP_001004311
          Length = 219

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  RERVRLLNR 9
          RER++ LNR
Sbjct: 75 RERIKNLNR 83
>XP_005256233
          Length = 2391

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    ERVRLLNR 9
            ERV+L+NR
Sbjct: 2053 ERVQLINR 2060
>XP_005256232
          Length = 2424

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    ERVRLLNR 9
            ERV+L+NR
Sbjct: 2086 ERVQLINR 2093
>XP_005256231
          Length = 2573

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    ERVRLLNR 9
            ERV+L+NR
Sbjct: 2560 ERVQLINR 2567
>XP_005256229
          Length = 2881

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    ERVRLLNR 9
            ERV+L+NR
Sbjct: 2543 ERVQLINR 2550
>XP_005256228
          Length = 2882

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    ERVRLLNR 9
            ERV+L+NR
Sbjct: 2544 ERVQLINR 2551
>XP_005256227
          Length = 2897

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    ERVRLLNR 9
            ERV+L+NR
Sbjct: 2559 ERVQLINR 2566
>XP_006721346
          Length = 2898

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    ERVRLLNR 9
            ERV+L+NR
Sbjct: 2560 ERVQLINR 2567
>XP_005256226
          Length = 2898

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    ERVRLLNR 9
            ERV+L+NR
Sbjct: 2560 ERVQLINR 2567
>XP_006721345
          Length = 2898

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    ERVRLLNR 9
            ERV+L+NR
Sbjct: 2560 ERVQLINR 2567
>XP_006721344
          Length = 2898

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    ERVRLLNR 9
            ERV+L+NR
Sbjct: 2560 ERVQLINR 2567
>XP_006721343
          Length = 2898

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    ERVRLLNR 9
            ERV+L+NR
Sbjct: 2560 ERVQLINR 2567
>XP_005256225
          Length = 2898

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    ERVRLLNR 9
            ERV+L+NR
Sbjct: 2560 ERVQLINR 2567
>XP_006710237
          Length = 274

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  ERVRLLNR 9
          ERVRLL R
Sbjct: 51 ERVRLLER 58
>NP_001234926
          Length = 1438

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RERVRLLNR 9
           RE+V LLN+
Sbjct: 422 REKVELLNQ 430
>NP_002947
          Length = 1427

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RERVRLLNR 9
           RE+V LLN+
Sbjct: 422 REKVELLNQ 430
>NP_065928
          Length = 4427

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   RERVRLLNR 9
           +ER+RLL++
Sbjct: 698 KERIRLLDK 706
>NP_937883
          Length = 1392

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RERVRLLNR 9
           RE+V LLN+
Sbjct: 422 REKVELLNQ 430
>XP_005256527
          Length = 4427

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   RERVRLLNR 9
           +ER+RLL++
Sbjct: 698 KERIRLLDK 706
>XP_006719618
          Length = 1394

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RERVRLLNR 9
           RE+V LLN+
Sbjct: 422 REKVELLNQ 430
>XP_006719617
          Length = 1401

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RERVRLLNR 9
           RE+V LLN+
Sbjct: 422 REKVELLNQ 430
>XP_006719616
          Length = 1405

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RERVRLLNR 9
           RE+V LLN+
Sbjct: 422 REKVELLNQ 430
>XP_006719615
          Length = 1429

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RERVRLLNR 9
           RE+V LLN+
Sbjct: 422 REKVELLNQ 430
>XP_006719614
          Length = 1440

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RERVRLLNR 9
           RE+V LLN+
Sbjct: 422 REKVELLNQ 430
>XP_005253652
          Length = 1440

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RERVRLLNR 9
           RE+V LLN+
Sbjct: 422 REKVELLNQ 430
>XP_005253651
          Length = 1440

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RERVRLLNR 9
           RE+V LLN+
Sbjct: 422 REKVELLNQ 430
>XP_005253650
          Length = 1440

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RERVRLLNR 9
           RE+V LLN+
Sbjct: 422 REKVELLNQ 430
>NP_003615
          Length = 562

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RERVRLLN 8
           R+RV+L+N
Sbjct: 262 RDRVKLIN 269
>NP_015561
          Length = 567

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RERVRLLN 8
           R+RV+L+N
Sbjct: 267 RDRVKLIN 274
>NP_060050
          Length = 708

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ERVRLLNR 9
           + VRLLNR
Sbjct: 298 DEVRLLNR 305
>NP_015559
          Length = 499

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RERVRLLN 8
           R+RV+L+N
Sbjct: 199 RDRVKLIN 206
>NP_002263
          Length = 520

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RERVRLLN 8
           RE+++LLN
Sbjct: 138 REQIKLLN 145
>XP_005259721
          Length = 494

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RERVRLLN 8
           R+RV+L+N
Sbjct: 194 RDRVKLIN 201
>XP_005269983
          Length = 708

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ERVRLLNR 9
           + VRLLNR
Sbjct: 298 DEVRLLNR 305
>XP_005269982
          Length = 734

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ERVRLLNR 9
           + VRLLNR
Sbjct: 324 DEVRLLNR 331
>XP_006717970
          Length = 734

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ERVRLLNR 9
           + VRLLNR
Sbjct: 324 DEVRLLNR 331
>NP_001263309
          Length = 851

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ERVRLLNR 9
           ER+ +LNR
Sbjct: 517 ERITMLNR 524
>NP_057733
          Length = 851

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ERVRLLNR 9
           ER+ +LNR
Sbjct: 517 ERITMLNR 524
>NP_659492
          Length = 404

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RERVRLLNR 9
           +ER+RLL +
Sbjct: 180 KERIRLLRQ 188
>NP_001008240
          Length = 343

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RERVRLLNR 9
           +ER+RLL +
Sbjct: 180 KERIRLLRQ 188
>NP_004632
          Length = 1027

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RERVRLLN 8
           +ER++LLN
Sbjct: 784 KERLQLLN 791
>NP_002462
          Length = 1939

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RERVRLLN 8
           R+R R+LN
Sbjct: 721 RQRYRILN 728
>NP_001182555
          Length = 1068

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RERVRLLN 8
           +ER++LLN
Sbjct: 768 KERLQLLN 775
>NP_006735
          Length = 201

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  RVRLLN 8
          RVRLLN
Sbjct: 78 RVRLLN 83
>NP_000248
          Length = 1935

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RERVRLLN 8
           R+R R+LN
Sbjct: 719 RQRYRILN 726
>NP_065935
          Length = 1983

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RERVRLLN 8
           R+R R+LN
Sbjct: 768 RQRYRILN 775
>NP_064612
          Length = 894

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RERVRLLNR 9
           +ER +LLN+
Sbjct: 457 KERSKLLNK 465
>XP_005261469
          Length = 394

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ERVRLLNR 9
           E VR++NR
Sbjct: 137 ETVRIINR 144
>XP_006723903
          Length = 1989

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RERVRLLN 8
           R+R R+LN
Sbjct: 768 RQRYRILN 775
>XP_006723902
          Length = 1787

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RERVRLLN 8
           R+R R+LN
Sbjct: 566 RQRYRILN 573
>XP_005256332
          Length = 507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RERVRLLNR 9
           +ER +LLN+
Sbjct: 308 KERSKLLNK 316
>XP_005267754
          Length = 1087

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RERVRLLN 8
           R+R R+LN
Sbjct: 719 RQRYRILN 726
>XP_005267753
          Length = 1935

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RERVRLLN 8
           R+R R+LN
Sbjct: 719 RQRYRILN 726
>XP_005267752
          Length = 993

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RERVRLLN 8
           R+R R+LN
Sbjct: 761 RQRYRILN 768
>XP_006720215
          Length = 1968

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RERVRLLN 8
           R+R R+LN
Sbjct: 750 RQRYRILN 757
>XP_006720214
          Length = 1978

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RERVRLLN 8
           R+R R+LN
Sbjct: 760 RQRYRILN 767
>XP_005267751
          Length = 1979

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RERVRLLN 8
           R+R R+LN
Sbjct: 761 RQRYRILN 768
>XP_005270080
          Length = 265

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   RVRLLN 8
           RVRLLN
Sbjct: 142 RVRLLN 147
>XP_005252668
          Length = 839

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RERVRLLN 8
           +ER++LLN
Sbjct: 539 KERLQLLN 546
>XP_006717572
          Length = 1003

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RERVRLLN 8
           +ER++LLN
Sbjct: 784 KERLQLLN 791
>XP_005252667
          Length = 1052

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RERVRLLN 8
           +ER++LLN
Sbjct: 752 KERLQLLN 759
>XP_005252666
          Length = 1057

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RERVRLLN 8
           +ER++LLN
Sbjct: 757 KERLQLLN 764
>XP_005252665
          Length = 1068

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RERVRLLN 8
           +ER++LLN
Sbjct: 768 KERLQLLN 775
>XP_005252663
          Length = 1084

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RERVRLLN 8
           +ER++LLN
Sbjct: 784 KERLQLLN 791
>XP_005252662
          Length = 1084

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   RERVRLLN 8
           +ER++LLN
Sbjct: 784 KERLQLLN 791
>NP_848544
          Length = 100

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  RERVRLL 7
          RER RLL
Sbjct: 72 RERARLL 78
>NP_055107
          Length = 412

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ERVRLLNR 9
           E VR++NR
Sbjct: 155 ETVRIINR 162
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.338    0.150    0.394 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 419,448
Number of extensions: 766
Number of successful extensions: 69
Number of sequences better than 10000.0: 69
Number of HSP's gapped: 69
Number of HSP's successfully gapped: 69
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)

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