Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_443179                                                              19     665
XP_005266703                                                           19     665
NP_996803                                                              17    3301
NP_060774                                                              16    5631
NP_001009555                                                           16    5631
NP_001122396                                                           16    5631
NP_001230278                                                           16    5631
XP_006714166                                                           16    5631
XP_006714165                                                           16    5631
XP_005262824                                                           16    5631
XP_006714164                                                           16    5631
XP_006714163                                                           16    5631
XP_006714162                                                           16    5631
XP_006714161                                                           16    5631
XP_006714160                                                           16    5631
XP_005262823                                                           16    5631
NP_001122395                                                           16    5631
NP_001180263                                                           16    7355
NP_001002292                                                           16    7355
NP_004960                                                              16    7355
NP_079187                                                              16    7355
NP_001159418                                                           16    7355
NP_001032412                                                           16    7355
NP_001099007                                                           16    7355
XP_005269823                                                           16    7355
XP_006712793                                                           16    7355
NP_060719                                                              15    9605
NP_001258968                                                           15    9605
NP_001011649                                                           15    9605
NP_065194                                                              15    9605
NP_001110                                                              15    9605
NP_054908                                                              15    9605
NP_001274420                                                           15    9605
NP_055994                                                              15    9605
NP_037530                                                              15    9605
NP_001608                                                              15    9605
NP_056065                                                              15    9605
NP_001185731                                                           15    9605
NP_001185730                                                           15    9605
NP_006381                                                              15    9605
NP_001171983                                                           15    9605
NP_003751                                                              15    9605
NP_001003800                                                           15    9605
NP_001078                                                              15    9605
XP_005259278                                                           15    9605
XP_006717248                                                           15    9605
XP_006717247                                                           15    9605
XP_006717246                                                           15    9605
XP_006717245                                                           15    9605
XP_006717244                                                           15    9605
XP_006717243                                                           15    9605
XP_006717242                                                           15    9605
XP_005247992                                                           15    9605
XP_005247991                                                           15    9605
XP_005247990                                                           15    9605
XP_005246382                                                           15    9605
XP_005264244                                                           15    9605
NP_001177924                                                           15    9605
>NP_443179
          Length = 2170

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    RAPVLLKK 8
            RAPVLLKK
Sbjct: 1784 RAPVLLKK 1791
>XP_005266703
          Length = 1501

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    RAPVLLKK 8
            RAPVLLKK
Sbjct: 1115 RAPVLLKK 1122
>NP_996803
          Length = 1137

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   RAPVLLKK 8
           RAPVLL++
Sbjct: 369 RAPVLLRR 376
>NP_060774
          Length = 360

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   APVLLKK 8
           APVLL+K
Sbjct: 201 APVLLRK 207
>NP_001009555
          Length = 790

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   PVLLKKS 9
           P+LLKKS
Sbjct: 142 PLLLKKS 148
>NP_001122396
          Length = 731

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   PVLLKKS 9
           P+LLKKS
Sbjct: 142 PLLLKKS 148
>NP_001230278
          Length = 767

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   PVLLKKS 9
           P+LLKKS
Sbjct: 142 PLLLKKS 148
>XP_006714166
          Length = 536

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   PVLLKKS 9
           P+LLKKS
Sbjct: 422 PLLLKKS 428
>XP_006714165
          Length = 790

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   PVLLKKS 9
           P+LLKKS
Sbjct: 142 PLLLKKS 148
>XP_005262824
          Length = 790

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   PVLLKKS 9
           P+LLKKS
Sbjct: 142 PLLLKKS 148
>XP_006714164
          Length = 1011

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   PVLLKKS 9
           P+LLKKS
Sbjct: 363 PLLLKKS 369
>XP_006714163
          Length = 1011

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   PVLLKKS 9
           P+LLKKS
Sbjct: 363 PLLLKKS 369
>XP_006714162
          Length = 1011

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   PVLLKKS 9
           P+LLKKS
Sbjct: 363 PLLLKKS 369
>XP_006714161
          Length = 1020

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   PVLLKKS 9
           P+LLKKS
Sbjct: 372 PLLLKKS 378
>XP_006714160
          Length = 1047

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   PVLLKKS 9
           P+LLKKS
Sbjct: 422 PLLLKKS 428
>XP_005262823
          Length = 1070

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   PVLLKKS 9
           P+LLKKS
Sbjct: 422 PLLLKKS 428
>NP_001122395
          Length = 767

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   PVLLKKS 9
           P+LLKKS
Sbjct: 142 PLLLKKS 148
>NP_001180263
          Length = 450

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RAPVLLKK 8
           R PVLL+K
Sbjct: 170 RPPVLLEK 177
>NP_001002292
          Length = 543

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RAPVLLKK 8
           R PVLL+K
Sbjct: 259 RPPVLLEK 266
>NP_004960
          Length = 1019

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RAPVLLKK 8
           + P+LLKK
Sbjct: 637 KQPILLKK 644
>NP_079187
          Length = 541

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RAPVLLKK 8
           R PVLL+K
Sbjct: 261 RPPVLLEK 268
>NP_001159418
          Length = 464

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  RAPVLLKK 8
          + P+LLKK
Sbjct: 82 KQPILLKK 89
>NP_001032412
          Length = 2649

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   RAPVLLKK 8
           R PVLL+K
Sbjct: 259 RRPVLLQK 266
>NP_001099007
          Length = 1687

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RAPVLLKKS 9
           + PVLL+K+
Sbjct: 888 KCPVLLRKN 896
>XP_005269823
          Length = 1019

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RAPVLLKK 8
           + P+LLKK
Sbjct: 637 KQPILLKK 644
>XP_006712793
          Length = 1887

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    RAPVLLKKS 9
            + PVLL+K+
Sbjct: 1088 KCPVLLRKN 1096
>NP_060719
          Length = 1893

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RAPVLLKKS 9
           R P+L+K S
Sbjct: 937 RLPILIKPS 945
>NP_001258968
          Length = 1663

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RAPVLLKKS 9
           R P+L+K S
Sbjct: 707 RLPILIKPS 715
>NP_001011649
          Length = 1814

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RAPVLLKKS 9
           R P+L+K S
Sbjct: 937 RLPILIKPS 945
>NP_065194
          Length = 1819

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    PVLLKKS 9
            PVL+K+S
Sbjct: 1481 PVLMKRS 1487
>NP_001110
          Length = 737

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RAPVLLKKS 9
           R P  LKKS
Sbjct: 723 RTPSFLKKS 731
>NP_054908
          Length = 768

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RAPVLLKKS 9
           R P  LKKS
Sbjct: 754 RTPSFLKKS 762
>NP_001274420
          Length = 1795

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RAPVLLKKS 9
           R P+ +KKS
Sbjct: 604 RKPIQIKKS 612
>NP_055994
          Length = 1297

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   APVLLKK 8
           +PVL+KK
Sbjct: 180 SPVLIKK 186
>NP_037530
          Length = 707

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   RAPVLLK 7
           RAP LLK
Sbjct: 467 RAPCLLK 473
>NP_001608
          Length = 726

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RAPVLLKKS 9
           R P  LKKS
Sbjct: 710 RTPSFLKKS 718
>NP_056065
          Length = 824

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RAPVLLKK 8
           R+P+LL K
Sbjct: 581 RSPILLPK 588
>NP_001185731
          Length = 1591

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    RAPVLLK 7
            R P+LLK
Sbjct: 1498 RVPILLK 1504
>NP_001185730
          Length = 1621

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    RAPVLLK 7
            R P+LLK
Sbjct: 1528 RVPILLK 1534
>NP_006381
          Length = 1037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   APVLLKKS 9
           A +LLKKS
Sbjct: 441 AEILLKKS 448
>NP_001171983
          Length = 726

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RAPVLLKKS 9
           R P  LKKS
Sbjct: 710 RTPSFLKKS 718
>NP_003751
          Length = 1585

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    RAPVLLK 7
            R P+LLK
Sbjct: 1492 RVPILLK 1498
>NP_001003800
          Length = 855

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RAPVLLKK 8
           R+P+LL K
Sbjct: 581 RSPILLPK 588
>NP_001078
          Length = 434

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   RAPVLL 6
           RAPVLL
Sbjct: 185 RAPVLL 190
>XP_005259278
          Length = 707

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   RAPVLLK 7
           RAP LLK
Sbjct: 467 RAPCLLK 473
>XP_006717248
          Length = 1664

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RAPVLLKKS 9
           R P+L+K S
Sbjct: 708 RLPILIKPS 716
>XP_006717247
          Length = 1670

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RAPVLLKKS 9
           R P+L+K S
Sbjct: 708 RLPILIKPS 716
>XP_006717246
          Length = 1820

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RAPVLLKKS 9
           R P+L+K S
Sbjct: 937 RLPILIKPS 945
>XP_006717245
          Length = 1861

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RAPVLLKKS 9
           R P+L+K S
Sbjct: 905 RLPILIKPS 913
>XP_006717244
          Length = 1867

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RAPVLLKKS 9
           R P+L+K S
Sbjct: 905 RLPILIKPS 913
>XP_006717243
          Length = 1889

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RAPVLLKKS 9
           R P+L+K S
Sbjct: 927 RLPILIKPS 935
>XP_006717242
          Length = 1898

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RAPVLLKKS 9
           R P+L+K S
Sbjct: 936 RLPILIKPS 944
>XP_005247992
          Length = 768

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RAPVLLKKS 9
           R P  LKKS
Sbjct: 754 RTPSFLKKS 762
>XP_005247991
          Length = 799

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RAPVLLKKS 9
           R P  LKKS
Sbjct: 785 RTPSFLKKS 793
>XP_005247990
          Length = 799

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   RAPVLLKKS 9
           R P  LKKS
Sbjct: 785 RTPSFLKKS 793
>XP_005246382
          Length = 435

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   RAPVLL 6
           RAPVLL
Sbjct: 186 RAPVLL 191
>XP_005264244
          Length = 1795

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   RAPVLLKKS 9
           R P+ +KKS
Sbjct: 604 RKPIQIKKS 612
>NP_001177924
          Length = 832

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   APVLLKKS 9
           A +LLKKS
Sbjct: 236 AEILLKKS 243
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.318    0.131    0.342 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 693,826
Number of extensions: 1123
Number of successful extensions: 58
Number of sequences better than 10000.0: 58
Number of HSP's gapped: 58
Number of HSP's successfully gapped: 58
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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