Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006715                                                              20     390
NP_005913                                                              20     390
XP_005267046                                                           20     390
XP_005267045                                                           20     390
NP_003110                                                              18    1935
XP_006721327                                                           18    1935
NP_001017535                                                           17    3301
NP_000367                                                              17    3301
NP_001017536                                                           17    3301
NP_001167555                                                           17    3301
NP_037406                                                              17    3301
XP_006719650                                                           17    3301
XP_006717836                                                           17    3301
XP_006717835                                                           17    3301
XP_006717834                                                           17    3301
XP_006717833                                                           17    3301
XP_005246746                                                           17    4312
NP_001186306                                                           16    5631
NP_055977                                                              16    5631
NP_001159777                                                           16    5631
NP_001011655                                                           16    5631
NP_001159778                                                           16    5631
NP_612408                                                              16    5631
XP_006713887                                                           16    5631
XP_006713886                                                           16    5631
XP_005269429                                                           16    5631
XP_005269428                                                           16    5631
NP_000611                                                              16    7355
NP_001191147                                                           16    7355
NP_001191142                                                           16    7355
NP_001191143                                                           16    7355
NP_689812                                                              16    7355
NP_002888                                                              16    7355
NP_000880                                                              16    7355
NP_058520                                                              16    7355
NP_001171182                                                           16    7355
NP_001003793                                                           16    7355
NP_001171183                                                           16    7355
NP_001003792                                                           16    7355
NP_055298                                                              16    7355
XP_006719608                                                           16    7355
XP_005269118                                                           16    7355
XP_006719607                                                           16    7355
XP_005269117                                                           16    7355
XP_006719606                                                           16    7355
XP_006719605                                                           16    7355
XP_005269116                                                           16    7355
XP_006719604                                                           16    7355
XP_006719491                                                           16    7355
XP_006719490                                                           16    7355
XP_006719489                                                           16    7355
XP_006719439                                                           16    7355
XP_005268909                                                           16    7355
XP_005268908                                                           16    7355
XP_006713172                                                           16    7355
XP_005265122                                                           16    7355
XP_005265120                                                           16    7355
XP_005265121                                                           16    7355
XP_006713171                                                           16    7355
XP_005265119                                                           16    7355
XP_005265118                                                           16    7355
XP_005265117                                                           16    7355
XP_006712738                                                           16    7355
XP_006712737                                                           16    7355
XP_006712736                                                           16    7355
XP_005246797                                                           16    7355
XP_005246798                                                           16    7355
XP_005246796                                                           16    7355
XP_006712735                                                           16    7355
XP_005246795                                                           16    7355
XP_005246794                                                           16    7355
XP_006712734                                                           16    7355
NP_002889                                                              16    7355
NP_037440                                                              15    9605
XP_005247460                                                           15    9605
XP_005247459                                                           15    9605
>NP_006715
          Length = 1558

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   RALGFAKML 9
           +ALGFAKML
Sbjct: 814 KALGFAKML 822
>NP_005913
          Length = 1608

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   RALGFAKML 9
           +ALGFAKML
Sbjct: 814 KALGFAKML 822
>XP_005267046
          Length = 1554

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   RALGFAKML 9
           +ALGFAKML
Sbjct: 814 KALGFAKML 822
>XP_005267045
          Length = 1604

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   RALGFAKML 9
           +ALGFAKML
Sbjct: 814 KALGFAKML 822
>NP_003110
          Length = 795

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   ALGFAKML 9
           ALGFA+ML
Sbjct: 603 ALGFAQML 610
>XP_006721327
          Length = 809

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   ALGFAKML 9
           ALGFA+ML
Sbjct: 603 ALGFAQML 610
>NP_001017535
          Length = 427

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RALGFAKML 9
           + +GFAKM+
Sbjct: 240 KVIGFAKMI 248
>NP_000367
          Length = 427

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RALGFAKML 9
           + +GFAKM+
Sbjct: 240 KVIGFAKMI 248
>NP_001017536
          Length = 477

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RALGFAKML 9
           + +GFAKM+
Sbjct: 290 KVIGFAKMI 298
>NP_001167555
          Length = 575

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RALGFAKML 9
           RALG+AK +
Sbjct: 275 RALGYAKAI 283
>NP_037406
          Length = 575

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RALGFAKML 9
           RALG+AK +
Sbjct: 275 RALGYAKAI 283
>XP_006719650
          Length = 427

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   RALGFAKML 9
           + +GFAKM+
Sbjct: 240 KVIGFAKMI 248
>XP_006717836
          Length = 406

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RALGFAKML 9
           RALG+AK +
Sbjct: 106 RALGYAKAI 114
>XP_006717835
          Length = 406

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RALGFAKML 9
           RALG+AK +
Sbjct: 106 RALGYAKAI 114
>XP_006717834
          Length = 487

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RALGFAKML 9
           RALG+AK +
Sbjct: 187 RALGYAKAI 195
>XP_006717833
          Length = 487

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RALGFAKML 9
           RALG+AK +
Sbjct: 187 RALGYAKAI 195
>XP_005246746
          Length = 898

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  RALGFAKML 9
          RALGF ++L
Sbjct: 2  RALGFPQLL 10
>NP_001186306
          Length = 720

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RALGFAK 7
           +ALGFAK
Sbjct: 434 QALGFAK 440
>NP_055977
          Length = 724

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RALGFAK 7
           +ALGFAK
Sbjct: 438 QALGFAK 444
>NP_001159777
          Length = 475

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RALGFAK 7
           +ALGFAK
Sbjct: 322 QALGFAK 328
>NP_001011655
          Length = 428

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RALGFAK 7
           +ALGFAK
Sbjct: 275 QALGFAK 281
>NP_001159778
          Length = 396

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RALGFAK 7
           +ALGFAK
Sbjct: 275 QALGFAK 281
>NP_612408
          Length = 438

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RALGFAK 7
           +ALGFAK
Sbjct: 275 QALGFAK 281
>XP_006713887
          Length = 336

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RALGFAK 7
           +ALGFAK
Sbjct: 172 QALGFAK 178
>XP_006713886
          Length = 382

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RALGFAK 7
           +ALGFAK
Sbjct: 218 QALGFAK 224
>XP_005269429
          Length = 427

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RALGFAK 7
           +ALGFAK
Sbjct: 275 QALGFAK 281
>XP_005269428
          Length = 439

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   RALGFAK 7
           +ALGFAK
Sbjct: 275 QALGFAK 281
>NP_000611
          Length = 1434

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RALGFAKM 8
           RA+GF K+
Sbjct: 732 RAIGFKKL 739
>NP_001191147
          Length = 1468

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RALGFAKM 8
           RA+GF K+
Sbjct: 732 RAIGFKKL 739
>NP_001191142
          Length = 1098

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RALGFAKM 8
           RA+GF K+
Sbjct: 396 RAIGFKKL 403
>NP_001191143
          Length = 1098

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RALGFAKM 8
           RA+GF K+
Sbjct: 396 RAIGFKKL 403
>NP_689812
          Length = 586

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  RALGFAKM 8
          RALG AK+
Sbjct: 11 RALGVAKL 18
>NP_002888
          Length = 403

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RALGFAKM 8
           R +GFA+M
Sbjct: 181 RGVGFARM 188
>NP_000880
          Length = 798

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RALGFAKML 9
           RALGF++ L
Sbjct: 458 RALGFSEEL 466
>NP_058520
          Length = 406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RALGFAKM 8
           R +GFA+M
Sbjct: 181 RGVGFARM 188
>NP_001171182
          Length = 421

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RALGFAKM 8
           R +GFA+M
Sbjct: 180 RGVGFARM 187
>NP_001003793
          Length = 437

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RALGFAKM 8
           R +GFA+M
Sbjct: 180 RGVGFARM 187
>NP_001171183
          Length = 433

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RALGFAKM 8
           R +GFA+M
Sbjct: 180 RGVGFARM 187
>NP_001003792
          Length = 419

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RALGFAKM 8
           R +GFA+M
Sbjct: 179 RGVGFARM 186
>NP_055298
          Length = 420

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RALGFAKM 8
           R +GFA+M
Sbjct: 180 RGVGFARM 187
>XP_006719608
          Length = 352

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  RALGFAKM 8
          R +GFA+M
Sbjct: 50 RGVGFARM 57
>XP_005269118
          Length = 388

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RALGFAKM 8
           R +GFA+M
Sbjct: 175 RGVGFARM 182
>XP_006719607
          Length = 407

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RALGFAKM 8
           R +GFA+M
Sbjct: 175 RGVGFARM 182
>XP_005269117
          Length = 419

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RALGFAKM 8
           R +GFA+M
Sbjct: 175 RGVGFARM 182
>XP_006719606
          Length = 429

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RALGFAKM 8
           R +GFA+M
Sbjct: 175 RGVGFARM 182
>XP_006719605
          Length = 448

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RALGFAKM 8
           R +GFA+M
Sbjct: 175 RGVGFARM 182
>XP_005269116
          Length = 448

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RALGFAKM 8
           R +GFA+M
Sbjct: 175 RGVGFARM 182
>XP_006719604
          Length = 477

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RALGFAKM 8
           R +GFA+M
Sbjct: 175 RGVGFARM 182
>XP_006719491
          Length = 1434

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RALGFAKM 8
           RA+GF K+
Sbjct: 732 RAIGFKKL 739
>XP_006719490
          Length = 1468

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RALGFAKM 8
           RA+GF K+
Sbjct: 732 RAIGFKKL 739
>XP_006719489
          Length = 1468

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RALGFAKM 8
           RA+GF K+
Sbjct: 732 RAIGFKKL 739
>XP_006719439
          Length = 782

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RALGFAKML 9
           RALGF++ L
Sbjct: 458 RALGFSEEL 466
>XP_005268909
          Length = 798

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RALGFAKML 9
           RALGF++ L
Sbjct: 458 RALGFSEEL 466
>XP_005268908
          Length = 798

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   RALGFAKML 9
           RALGF++ L
Sbjct: 458 RALGFSEEL 466
>XP_006713172
          Length = 291

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RALGFAKM 8
           R +GFA+M
Sbjct: 180 RGVGFARM 187
>XP_005265122
          Length = 328

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  RALGFAKM 8
          R +GFA+M
Sbjct: 71 RGVGFARM 78
>XP_005265120
          Length = 342

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  RALGFAKM 8
          R +GFA+M
Sbjct: 85 RGVGFARM 92
>XP_005265121
          Length = 342

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  RALGFAKM 8
          R +GFA+M
Sbjct: 85 RGVGFARM 92
>XP_006713171
          Length = 403

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RALGFAKM 8
           R +GFA+M
Sbjct: 146 RGVGFARM 153
>XP_005265119
          Length = 419

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RALGFAKM 8
           R +GFA+M
Sbjct: 180 RGVGFARM 187
>XP_005265118
          Length = 420

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RALGFAKM 8
           R +GFA+M
Sbjct: 180 RGVGFARM 187
>XP_005265117
          Length = 436

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RALGFAKM 8
           R +GFA+M
Sbjct: 179 RGVGFARM 186
>XP_006712738
          Length = 403

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RALGFAKM 8
           R +GFA+M
Sbjct: 162 RGVGFARM 169
>XP_006712737
          Length = 405

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RALGFAKM 8
           R +GFA+M
Sbjct: 183 RGVGFARM 190
>XP_006712736
          Length = 408

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RALGFAKM 8
           R +GFA+M
Sbjct: 183 RGVGFARM 190
>XP_005246797
          Length = 419

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RALGFAKM 8
           R +GFA+M
Sbjct: 181 RGVGFARM 188
>XP_005246798
          Length = 419

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RALGFAKM 8
           R +GFA+M
Sbjct: 178 RGVGFARM 185
>XP_005246796
          Length = 420

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RALGFAKM 8
           R +GFA+M
Sbjct: 179 RGVGFARM 186
>XP_006712735
          Length = 421

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RALGFAKM 8
           R +GFA+M
Sbjct: 183 RGVGFARM 190
>XP_005246795
          Length = 421

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RALGFAKM 8
           R +GFA+M
Sbjct: 180 RGVGFARM 187
>XP_005246794
          Length = 422

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RALGFAKM 8
           R +GFA+M
Sbjct: 181 RGVGFARM 188
>XP_006712734
          Length = 424

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RALGFAKM 8
           R +GFA+M
Sbjct: 183 RGVGFARM 190
>NP_002889
          Length = 407

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   RALGFAKM 8
           R +GFA+M
Sbjct: 175 RGVGFARM 182
>NP_037440
          Length = 319

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   GFAKML 9
           GFAKM+
Sbjct: 129 GFAKMI 134
>XP_005247460
          Length = 319

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   GFAKML 9
           GFAKM+
Sbjct: 129 GFAKMI 134
>XP_005247459
          Length = 319

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   GFAKML 9
           GFAKM+
Sbjct: 129 GFAKMI 134
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.342    0.148    0.413 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 362,175
Number of extensions: 287
Number of successful extensions: 76
Number of sequences better than 10000.0: 76
Number of HSP's gapped: 76
Number of HSP's successfully gapped: 76
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.6 bits)
S2: 28 (15.4 bits)

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