Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000258                                                              18    1135
NP_001035957                                                           18    1135
XP_006721990                                                           18    1135
XP_006721989                                                           18    1135
XP_005258041                                                           18    1135
XP_006721988                                                           18    1135
XP_006721987                                                           18    1135
XP_006721986                                                           18    1135
XP_005258040                                                           18    1135
XP_006721985                                                           18    1135
NP_002728                                                              17    2528
NP_689418                                                              16    5631
NP_115545                                                              16    5631
NP_001017535                                                           16    7355
NP_000367                                                              16    7355
NP_001017536                                                           16    7355
NP_079421                                                              16    7355
XP_006719650                                                           16    7355
XP_005270233                                                           16    7355
XP_005270231                                                           16    7355
XP_005270230                                                           16    7355
XP_005270229                                                           16    7355
XP_005270228                                                           16    7355
NP_001273331                                                           15    9605
NP_000237                                                              15    9605
NP_056041                                                              15    9605
NP_001230332                                                           15    9605
XP_006720946                                                           15    9605
XP_005255380                                                           15    9605
XP_006720945                                                           15    9605
XP_006720944                                                           15    9605
XP_005255378                                                           15    9605
XP_005255377                                                           15    9605
XP_006720943                                                           15    9605
XP_005255273                                                           15    9605
XP_005255272                                                           15    9605
XP_005255271                                                           15    9605
XP_005255270                                                           15    9605
XP_005255268                                                           15    9605
XP_005255267                                                           15    9605
NP_001074001                                                           15    9605
>NP_000258
          Length = 2818

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QRVIAILDK 9
            QRV AILDK
Sbjct: 1948 QRVTAILDK 1956
>NP_001035957
          Length = 2839

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QRVIAILDK 9
            QRV AILDK
Sbjct: 1969 QRVTAILDK 1977
>XP_006721990
          Length = 2823

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QRVIAILDK 9
            QRV AILDK
Sbjct: 1979 QRVTAILDK 1987
>XP_006721989
          Length = 2823

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QRVIAILDK 9
            QRV AILDK
Sbjct: 1979 QRVTAILDK 1987
>XP_005258041
          Length = 2836

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QRVIAILDK 9
            QRV AILDK
Sbjct: 1948 QRVTAILDK 1956
>XP_006721988
          Length = 2846

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QRVIAILDK 9
            QRV AILDK
Sbjct: 1958 QRVTAILDK 1966
>XP_006721987
          Length = 2849

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QRVIAILDK 9
            QRV AILDK
Sbjct: 1979 QRVTAILDK 1987
>XP_006721986
          Length = 2854

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QRVIAILDK 9
            QRV AILDK
Sbjct: 1966 QRVTAILDK 1974
>XP_005258040
          Length = 2857

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QRVIAILDK 9
            QRV AILDK
Sbjct: 1969 QRVTAILDK 1977
>XP_006721985
          Length = 2867

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QRVIAILDK 9
            QRV AILDK
Sbjct: 1979 QRVTAILDK 1987
>NP_002728
          Length = 672

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   QRVIAILDK 9
           +RV+A+LDK
Sbjct: 388 KRVLALLDK 396
>NP_689418
          Length = 839

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QRVIAILDK 9
           QR++ I+DK
Sbjct: 255 QRLVTIVDK 263
>NP_115545
          Length = 780

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RVIAILD 8
           RVIA+LD
Sbjct: 236 RVIAVLD 242
>NP_001017535
          Length = 427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QRVIAIL 7
           QR+IAIL
Sbjct: 129 QRIIAIL 135
>NP_000367
          Length = 427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QRVIAIL 7
           QR+IAIL
Sbjct: 129 QRIIAIL 135
>NP_001017536
          Length = 477

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QRVIAIL 7
           QR+IAIL
Sbjct: 179 QRIIAIL 185
>NP_079421
          Length = 1665

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QRVIAILDK 9
            ++ IA+LDK
Sbjct: 1551 EQTIAVLDK 1559
>XP_006719650
          Length = 427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   QRVIAIL 7
           QR+IAIL
Sbjct: 129 QRIIAIL 135
>XP_005270233
          Length = 927

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QRVIAILDK 9
           ++ IA+LDK
Sbjct: 813 EQTIAVLDK 821
>XP_005270231
          Length = 1627

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QRVIAILDK 9
            ++ IA+LDK
Sbjct: 1513 EQTIAVLDK 1521
>XP_005270230
          Length = 1627

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QRVIAILDK 9
            ++ IA+LDK
Sbjct: 1513 EQTIAVLDK 1521
>XP_005270229
          Length = 1637

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QRVIAILDK 9
            ++ IA+LDK
Sbjct: 1523 EQTIAVLDK 1531
>XP_005270228
          Length = 1666

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QRVIAILDK 9
            ++ IA+LDK
Sbjct: 1552 EQTIAVLDK 1560
>NP_001273331
          Length = 1131

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RVIAILDK 9
           RVIA+L K
Sbjct: 415 RVIAVLGK 422
>NP_000237
          Length = 1130

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RVIAILDK 9
           RVIA+L K
Sbjct: 414 RVIAVLGK 421
>NP_056041
          Length = 1053

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QRVIAILD 8
           QR+ A+LD
Sbjct: 821 QRIAALLD 828
>NP_001230332
          Length = 906

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QRVIAILD 8
           QR+ A+LD
Sbjct: 803 QRIAALLD 810
>XP_006720946
          Length = 1081

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RVIAILDK 9
           RVIA+L K
Sbjct: 365 RVIAVLGK 372
>XP_005255380
          Length = 1082

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RVIAILDK 9
           RVIA+L K
Sbjct: 366 RVIAVLGK 373
>XP_006720945
          Length = 1096

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RVIAILDK 9
           RVIA+L K
Sbjct: 380 RVIAVLGK 387
>XP_006720944
          Length = 1097

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RVIAILDK 9
           RVIA+L K
Sbjct: 381 RVIAVLGK 388
>XP_005255378
          Length = 1145

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RVIAILDK 9
           RVIA+L K
Sbjct: 429 RVIAVLGK 436
>XP_005255377
          Length = 1146

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RVIAILDK 9
           RVIA+L K
Sbjct: 430 RVIAVLGK 437
>XP_006720943
          Length = 1208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RVIAILDK 9
           RVIA+L K
Sbjct: 492 RVIAVLGK 499
>XP_005255273
          Length = 884

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QRVIAILD 8
           QR+ A+LD
Sbjct: 821 QRIAALLD 828
>XP_005255272
          Length = 925

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QRVIAILD 8
           QR+ A+LD
Sbjct: 821 QRIAALLD 828
>XP_005255271
          Length = 998

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QRVIAILD 8
           QR+ A+LD
Sbjct: 821 QRIAALLD 828
>XP_005255270
          Length = 1035

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QRVIAILD 8
           QR+ A+LD
Sbjct: 803 QRIAALLD 810
>XP_005255268
          Length = 1037

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QRVIAILD 8
           QR+ A+LD
Sbjct: 805 QRIAALLD 812
>XP_005255267
          Length = 1051

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QRVIAILD 8
           QR+ A+LD
Sbjct: 819 QRIAALLD 826
>NP_001074001
          Length = 1100

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VIAILDK 9
           +IA+LDK
Sbjct: 411 IIALLDK 417
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.334    0.148    0.366 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 359,948
Number of extensions: 548
Number of successful extensions: 41
Number of sequences better than 10000.0: 41
Number of HSP's gapped: 41
Number of HSP's successfully gapped: 41
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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