Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005148                                                              19     869
NP_009297                                                              19     869
NP_055603                                                              16    5631
NP_150088                                                              16    5631
XP_006717402                                                           16    5631
XP_006717401                                                           16    5631
XP_005252380                                                           16    5631
XP_005252379                                                           16    5631
XP_005252378                                                           16    5631
XP_005252377                                                           16    5631
NP_001265473                                                           16    7355
NP_000057                                                              16    7355
NP_001096121                                                           16    7355
NP_001265472                                                           16    7355
NP_998770                                                              16    7355
XP_006722698                                                           16    7355
XP_006722697                                                           16    7355
XP_006716616                                                           16    7355
XP_005271223                                                           16    7355
XP_006710936                                                           16    7355
NP_113676                                                              15    9605
NP_003413                                                              15    9605
NP_002902                                                              15    9605
NP_932172                                                              15    9605
XP_006723423                                                           15    9605
XP_006723422                                                           15    9605
XP_006723421                                                           15    9605
XP_005259261                                                           15    9605
XP_005259260                                                           15    9605
XP_005260072                                                           15    9605
XP_006718983                                                           15    9605
XP_006718982                                                           15    9605
XP_006718981                                                           15    9605
XP_006718980                                                           15    9605
XP_006718979                                                           15    9605
XP_005248339                                                           15    9605
NP_115828                                                              15    9605
NP_001139500                                                           15    9605
NP_079280                                                              15    9605
>NP_005148
          Length = 1130

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QRSILLRYE 9
           QRSI LRYE
Sbjct: 160 QRSISLRYE 168
>NP_009297
          Length = 1149

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QRSILLRYE 9
           QRSI LRYE
Sbjct: 179 QRSISLRYE 187
>NP_055603
          Length = 442

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QRSILLRY 8
           +RS+LL+Y
Sbjct: 258 ERSLLLKY 265
>NP_150088
          Length = 442

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QRSILLRY 8
           +RS+LL+Y
Sbjct: 258 ERSLLLKY 265
>XP_006717402
          Length = 392

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QRSILLRY 8
           +RS+LL+Y
Sbjct: 208 ERSLLLKY 215
>XP_006717401
          Length = 392

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QRSILLRY 8
           +RS+LL+Y
Sbjct: 208 ERSLLLKY 215
>XP_005252380
          Length = 442

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QRSILLRY 8
           +RS+LL+Y
Sbjct: 258 ERSLLLKY 265
>XP_005252379
          Length = 442

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QRSILLRY 8
           +RS+LL+Y
Sbjct: 258 ERSLLLKY 265
>XP_005252378
          Length = 442

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QRSILLRY 8
           +RS+LL+Y
Sbjct: 258 ERSLLLKY 265
>XP_005252377
          Length = 442

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QRSILLRY 8
           +RS+LL+Y
Sbjct: 258 ERSLLLKY 265
>NP_001265473
          Length = 529

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RSILLRYE 9
           RS++L YE
Sbjct: 247 RSLMLHYE 254
>NP_000057
          Length = 591

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RSILLRYE 9
           RS++L YE
Sbjct: 309 RSLMLHYE 316
>NP_001096121
          Length = 538

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QRSILLRYE 9
           QRS L+R+E
Sbjct: 475 QRSSLVRHE 483
>NP_001265472
          Length = 539

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RSILLRYE 9
           RS++L YE
Sbjct: 257 RSLMLHYE 264
>NP_998770
          Length = 492

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QRSILLRYE 9
           Q SILLR++
Sbjct: 216 QSSILLRHQ 224
>XP_006722698
          Length = 388

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QRSILLRYE 9
           QRS L+R+E
Sbjct: 325 QRSSLVRHE 333
>XP_006722697
          Length = 537

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QRSILLRYE 9
           QRS L+R+E
Sbjct: 474 QRSSLVRHE 482
>XP_006716616
          Length = 492

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QRSILLRYE 9
           Q SILLR++
Sbjct: 216 QSSILLRHQ 224
>XP_005271223
          Length = 628

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RSILLRYE 9
           RS++L YE
Sbjct: 346 RSLMLHYE 353
>XP_006710936
          Length = 630

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RSILLRYE 9
           RS++L YE
Sbjct: 348 RSLMLHYE 355
>NP_113676
          Length = 705

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ILLRYE 9
           +LLRYE
Sbjct: 243 VLLRYE 248
>NP_003413
          Length = 734

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QRSILLRYE 9
           QRS LLR++
Sbjct: 367 QRSNLLRHQ 375
>NP_002902
          Length = 1118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ILLRYE 9
           +LLRYE
Sbjct: 292 VLLRYE 297
>NP_932172
          Length = 734

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QRSILLRYE 9
           QRS LLR++
Sbjct: 367 QRSNLLRHQ 375
>XP_006723423
          Length = 734

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QRSILLRYE 9
           QRS LLR++
Sbjct: 367 QRSNLLRHQ 375
>XP_006723422
          Length = 734

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QRSILLRYE 9
           QRS LLR++
Sbjct: 367 QRSNLLRHQ 375
>XP_006723421
          Length = 719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QRSILLRYE 9
           QRS LLR++
Sbjct: 352 QRSNLLRHQ 360
>XP_005259261
          Length = 775

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QRSILLRYE 9
           QRS LLR++
Sbjct: 408 QRSNLLRHQ 416
>XP_005259260
          Length = 775

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   QRSILLRYE 9
           QRS LLR++
Sbjct: 408 QRSNLLRHQ 416
>XP_005260072
          Length = 1129

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   ILLRYE 9
           +LLRYE
Sbjct: 292 VLLRYE 297
>XP_006718983
          Length = 702

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RSILLRYE 9
           +SILL+Y+
Sbjct: 438 QSILLKYQ 445
>XP_006718982
          Length = 727

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RSILLRYE 9
           +SILL+Y+
Sbjct: 438 QSILLKYQ 445
>XP_006718981
          Length = 763

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RSILLRYE 9
           +SILL+Y+
Sbjct: 438 QSILLKYQ 445
>XP_006718980
          Length = 779

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RSILLRYE 9
           +SILL+Y+
Sbjct: 438 QSILLKYQ 445
>XP_006718979
          Length = 844

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RSILLRYE 9
           +SILL+Y+
Sbjct: 438 QSILLKYQ 445
>XP_005248339
          Length = 2584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  SILLRY 8
          SILLRY
Sbjct: 12 SILLRY 17
>NP_115828
          Length = 628

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   QRSILLRYE 9
           QRS  LRYE
Sbjct: 298 QRSNGLRYE 306
>NP_001139500
          Length = 628

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   QRSILLRYE 9
           QRS  LRYE
Sbjct: 298 QRSNGLRYE 306
>NP_079280
          Length = 951

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RSILLRYE 9
           +SILL+Y+
Sbjct: 438 QSILLKYQ 445
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.331    0.144    0.372 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 396,775
Number of extensions: 787
Number of successful extensions: 39
Number of sequences better than 10000.0: 39
Number of HSP's gapped: 39
Number of HSP's successfully gapped: 39
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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