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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001013433                                                           18    1135
NP_060785                                                              18    1135
NP_361014                                                              18    1135
NP_003599                                                              17    4312
NP_001258867                                                           16    5631
NP_001401                                                              16    5631
NP_001123620                                                           16    7355
NP_001123619                                                           16    7355
NP_115734                                                              16    7355
NP_001123618                                                           16    7355
NP_060606                                                              15    9605
XP_006719085                                                           15    9605
XP_006719084                                                           15    9605
XP_006719083                                                           15    9605
NP_001138430                                                           15    9605

>NP_001013433
          Length = 589

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QRRRIISVQ 9
           QRRRI SVQ
Sbjct: 103 QRRRITSVQ 111



>NP_060785
          Length = 627

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QRRRIISVQ 9
           QRRRI SVQ
Sbjct: 141 QRRRITSVQ 149



>NP_361014
          Length = 707

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   QRRRIISVQ 9
           QRRRI SVQ
Sbjct: 221 QRRRITSVQ 229



>NP_003599
          Length = 337

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   QRRRIISV 8
           QR+RI+SV
Sbjct: 318 QRKRILSV 325



>NP_001258867
          Length = 2845

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QRRRIISVQ 9
            + RRI+SVQ
Sbjct: 2021 ETRRILSVQ 2029



>NP_001401
          Length = 2778

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    QRRRIISVQ 9
            + RRI+SVQ
Sbjct: 1954 ETRRILSVQ 1962



>NP_001123620
          Length = 456

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QRRRIISVQ 9
           +RRRI+ V+
Sbjct: 378 ERRRILEVE 386



>NP_001123619
          Length = 456

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QRRRIISVQ 9
           +RRRI+ V+
Sbjct: 378 ERRRILEVE 386



>NP_115734
          Length = 488

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QRRRIISVQ 9
           +RRRI+ V+
Sbjct: 410 ERRRILEVE 418



>NP_001123618
          Length = 456

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QRRRIISVQ 9
           +RRRI+ V+
Sbjct: 378 ERRRILEVE 386



>NP_060606
          Length = 3477

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    QRRRIISVQ 9
            QR+ +IS+Q
Sbjct: 1751 QRKAVISLQ 1759



>XP_006719085
          Length = 684

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   RRIISVQ 9
           RRIISV+
Sbjct: 419 RRIISVE 425



>XP_006719084
          Length = 732

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   RRIISVQ 9
           RRIISV+
Sbjct: 470 RRIISVE 476



>XP_006719083
          Length = 735

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   RRIISVQ 9
           RRIISV+
Sbjct: 470 RRIISVE 476



>NP_001138430
          Length = 731

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   RRIISVQ 9
           RRIISV+
Sbjct: 469 RRIISVE 475



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.341    0.143    0.348 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 372,301
Number of extensions: 249
Number of successful extensions: 15
Number of sequences better than 10000.0: 15
Number of HSP's gapped: 15
Number of HSP's successfully gapped: 15
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.6 bits)
S2: 28 (15.4 bits)