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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006197                                                              18    1135
XP_005265800                                                           18    1135
XP_006714103                                                           18    1135
XP_006714102                                                           18    1135
XP_006726603                                                           18    1482
XP_006725215                                                           18    1482
XP_006719239                                                           18    1482
XP_006719237                                                           18    1482
NP_277047                                                              16    5631
NP_940820                                                              16    7355
NP_001028776                                                           16    7355
NP_001028777                                                           16    7355
NP_055266                                                              16    7355
NP_079083                                                              16    7355
XP_006715751                                                           16    7355
XP_005249757                                                           16    7355
XP_006715750                                                           16    7355
NP_904325                                                              15    9605
NP_009029                                                              15    9605
NP_001826                                                              15    9605
NP_001264661                                                           15    9605
NP_003725                                                              15    9605
XP_006726806                                                           15    9605
XP_006724391                                                           15    9605
XP_005261338                                                           15    9605
XP_005277858                                                           15    9605
XP_006724390                                                           15    9605
XP_006724389                                                           15    9605
XP_005277857                                                           15    9605
XP_006722322                                                           15    9605
XP_006719964                                                           15    9605
XP_006719963                                                           15    9605
XP_006719962                                                           15    9605
XP_006719961                                                           15    9605
XP_006719960                                                           15    9605
XP_005266656                                                           15    9605
XP_006710095                                                           15    9605
NP_004285                                                              15    9605

>NP_006197
          Length = 1089

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QRLSADSVY 9
            QRLSADS Y
Sbjct: 1010 QRLSADSGY 1018



>XP_005265800
          Length = 1089

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QRLSADSVY 9
            QRLSADS Y
Sbjct: 1010 QRLSADSGY 1018



>XP_006714103
          Length = 1111

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QRLSADSVY 9
            QRLSADS Y
Sbjct: 1032 QRLSADSGY 1040



>XP_006714102
          Length = 1114

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    QRLSADSVY 9
            QRLSADS Y
Sbjct: 1035 QRLSADSGY 1043



>XP_006726603
          Length = 1264

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   QRLSADSVY 9
           Q+LSA+SVY
Sbjct: 414 QQLSAESVY 422



>XP_006725215
          Length = 1264

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   QRLSADSVY 9
           Q+LSA+SVY
Sbjct: 414 QQLSAESVY 422



>XP_006719239
          Length = 1066

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   QRLSADSVY 9
           Q+LSA+SVY
Sbjct: 629 QQLSAESVY 637



>XP_006719237
          Length = 1263

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   QRLSADSVY 9
           Q+LSA+SVY
Sbjct: 414 QQLSAESVY 422



>NP_277047
          Length = 417

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   QRLSADSVY 9
           +RL+AD+V+
Sbjct: 114 ERLAADTVF 122



>NP_940820
          Length = 887

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QRLSADSV 8
           Q+LSAD V
Sbjct: 742 QKLSADQV 749



>NP_001028776
          Length = 852

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QRLSADSV 8
           Q+LSAD V
Sbjct: 707 QKLSADQV 714



>NP_001028777
          Length = 882

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QRLSADSV 8
           Q+LSAD V
Sbjct: 737 QKLSADQV 744



>NP_055266
          Length = 847

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QRLSADSV 8
           Q+LSAD V
Sbjct: 702 QKLSADQV 709



>NP_079083
          Length = 321

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  SADSVY 9
          SADSVY
Sbjct: 21 SADSVY 26



>XP_006715751
          Length = 796

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QRLSADSV 8
           Q+LSAD V
Sbjct: 651 QKLSADQV 658



>XP_005249757
          Length = 886

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QRLSADSV 8
           Q+LSAD V
Sbjct: 742 QKLSADQV 749



>XP_006715750
          Length = 887

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QRLSADSV 8
           Q+LSAD V
Sbjct: 742 QKLSADQV 749



>NP_904325
          Length = 1153

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   QRLSADS 7
           QRL ADS
Sbjct: 657 QRLDADS 663



>NP_009029
          Length = 1640

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   RLSADSVY 9
           R+SAD+++
Sbjct: 297 RISADTIF 304



>NP_001826
          Length = 1583

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   RLSADSVY 9
           R+SAD+++
Sbjct: 297 RISADTIF 304



>NP_001264661
          Length = 220

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   SADSVY 9
           SADS+Y
Sbjct: 176 SADSIY 181



>NP_003725
          Length = 763

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   SADSVY 9
           SADS+Y
Sbjct: 719 SADSIY 724



>XP_006726806
          Length = 259

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   SADSVY 9
           SADS+Y
Sbjct: 215 SADSIY 220



>XP_006724391
          Length = 1567

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   RLSADSVY 9
           R+SAD+++
Sbjct: 318 RISADTIF 325



>XP_005261338
          Length = 1570

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   RLSADSVY 9
           R+SAD+++
Sbjct: 318 RISADTIF 325



>XP_005277858
          Length = 1604

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   RLSADSVY 9
           R+SAD+++
Sbjct: 318 RISADTIF 325



>XP_006724390
          Length = 1623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   RLSADSVY 9
           R+SAD+++
Sbjct: 280 RISADTIF 287



>XP_006724389
          Length = 1653

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   RLSADSVY 9
           R+SAD+++
Sbjct: 318 RISADTIF 325



>XP_005277857
          Length = 1661

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   RLSADSVY 9
           R+SAD+++
Sbjct: 318 RISADTIF 325



>XP_006722322
          Length = 259

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   SADSVY 9
           SADS+Y
Sbjct: 215 SADSIY 220



>XP_006719964
          Length = 444

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   RLSADSVY 9
           R+S D VY
Sbjct: 241 RISGDGVY 248



>XP_006719963
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   RLSADSVY 9
           R+S D VY
Sbjct: 241 RISGDGVY 248



>XP_006719962
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   RLSADSVY 9
           R+S D VY
Sbjct: 241 RISGDGVY 248



>XP_006719961
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   RLSADSVY 9
           R+S D VY
Sbjct: 241 RISGDGVY 248



>XP_006719960
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   RLSADSVY 9
           R+S D VY
Sbjct: 241 RISGDGVY 248



>XP_005266656
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   RLSADSVY 9
           R+S D VY
Sbjct: 241 RISGDGVY 248



>XP_006710095
          Length = 259

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   SADSVY 9
           SADS+Y
Sbjct: 215 SADSIY 220



>NP_004285
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   RLSADSVY 9
           R+S D VY
Sbjct: 241 RISGDGVY 248



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.313    0.122    0.308 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 391,161
Number of extensions: 536
Number of successful extensions: 38
Number of sequences better than 10000.0: 38
Number of HSP's gapped: 38
Number of HSP's successfully gapped: 38
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)