Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001895                                                              18    1135
NP_001091680                                                           18    1135
NP_001091679                                                           18    1135
XP_006713048                                                           18    1135
XP_006713047                                                           18    1135
XP_006713046                                                           18    1135
XP_005264943                                                           18    1135
NP_001277114                                                           17    3301
NP_068375                                                              17    3301
NP_004870                                                              17    4312
NP_001277064                                                           17    4312
NP_001001323                                                           16    5631
NP_001673                                                              16    5631
NP_001123537                                                           16    5631
NP_004136                                                              16    5631
XP_006722821                                                           16    5631
XP_006722820                                                           16    5631
XP_005259972                                                           16    5631
XP_006722819                                                           16    5631
XP_006722818                                                           16    5631
XP_005268976                                                           16    5631
NP_619639                                                              16    7355
NP_733842                                                              16    7355
NP_660187                                                              16    7355
NP_149163                                                              16    7355
NP_115972                                                              16    7355
NP_001186434                                                           16    7355
NP_899067                                                              16    7355
NP_001268436                                                           16    7355
NP_542403                                                              16    7355
NP_899069                                                              16    7355
NP_001186435                                                           16    7355
NP_005994                                                              16    7355
NP_001159392                                                           15    9605
NP_000925                                                              15    9605
NP_001159393                                                           15    9605
NP_001231933                                                           15    9605
NP_005588                                                              15    9605
NP_001026885                                                           15    9605
NP_001231931                                                           15    9605
NP_848639                                                              15    9605
NP_056100                                                              15    9605
NP_443066                                                              15    9605
NP_997289                                                              15    9605
NP_001166094                                                           15    9605
NP_995315                                                              15    9605
NP_002490                                                              15    9605
NP_001231934                                                           15    9605
XP_006725318                                                           15    9605
XP_005258911                                                           15    9605
XP_005258910                                                           15    9605
XP_005259621                                                           15    9605
XP_006722822                                                           15    9605
XP_005259620                                                           15    9605
XP_006722494                                                           15    9605
XP_005256760                                                           15    9605
XP_005256758                                                           15    9605
XP_005256757                                                           15    9605
XP_005256756                                                           15    9605
XP_005256755                                                           15    9605
XP_005254473                                                           15    9605
XP_005254472                                                           15    9605
XP_005254471                                                           15    9605
XP_005254470                                                           15    9605
XP_005254469                                                           15    9605
XP_005254468                                                           15    9605
XP_005254467                                                           15    9605
XP_005254465                                                           15    9605
XP_005250956                                                           15    9605
NP_001166095                                                           15    9605
NP_001153019                                                           15    9605
NP_000828                                                              15    9605
NP_001009184                                                           15    9605
NP_996776                                                              15    9605
>NP_001895
          Length = 781

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  QQSYLVSGI 9
          QQSYL SGI
Sbjct: 27 QQSYLDSGI 35
>NP_001091680
          Length = 781

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  QQSYLVSGI 9
          QQSYL SGI
Sbjct: 27 QQSYLDSGI 35
>NP_001091679
          Length = 781

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  QQSYLVSGI 9
          QQSYL SGI
Sbjct: 27 QQSYLDSGI 35
>XP_006713048
          Length = 720

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  QQSYLVSGI 9
          QQSYL SGI
Sbjct: 27 QQSYLDSGI 35
>XP_006713047
          Length = 774

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  QQSYLVSGI 9
          QQSYL SGI
Sbjct: 20 QQSYLDSGI 28
>XP_006713046
          Length = 774

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  QQSYLVSGI 9
          QQSYL SGI
Sbjct: 20 QQSYLDSGI 28
>XP_005264943
          Length = 781

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  QQSYLVSGI 9
          QQSYL SGI
Sbjct: 27 QQSYLDSGI 35
>NP_001277114
          Length = 931

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QSYLVSG 8
           QSY+VSG
Sbjct: 202 QSYIVSG 208
>NP_068375
          Length = 941

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QSYLVSG 8
           QSY+VSG
Sbjct: 212 QSYIVSG 218
>NP_004870
          Length = 340

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QQSYLVSG 8
           Q SY++SG
Sbjct: 256 QSSYIISG 263
>NP_001277064
          Length = 326

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   QQSYLVSG 8
           Q SY++SG
Sbjct: 242 QSSYIISG 249
>NP_001001323
          Length = 1176

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SYLVSGI 9
           SYLV+GI
Sbjct: 512 SYLVTGI 518
>NP_001673
          Length = 1220

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SYLVSGI 9
           SYLV+GI
Sbjct: 512 SYLVTGI 518
>NP_001123537
          Length = 2022

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   QQSYLVSGI 9
           Q SYL SGI
Sbjct: 301 QVSYLESGI 309
>NP_004136
          Length = 2157

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   QQSYLVSGI 9
           Q SYL SGI
Sbjct: 301 QVSYLESGI 309
>XP_006722821
          Length = 1462

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   QQSYLVSGI 9
           Q SYL SGI
Sbjct: 301 QVSYLESGI 309
>XP_006722820
          Length = 2140

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   QQSYLVSGI 9
           Q SYL SGI
Sbjct: 301 QVSYLESGI 309
>XP_005259972
          Length = 2141

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   QQSYLVSGI 9
           Q SYL SGI
Sbjct: 301 QVSYLESGI 309
>XP_006722819
          Length = 2156

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   QQSYLVSGI 9
           Q SYL SGI
Sbjct: 301 QVSYLESGI 309
>XP_006722818
          Length = 2157

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   QQSYLVSGI 9
           Q SYL SGI
Sbjct: 301 QVSYLESGI 309
>XP_005268976
          Length = 1249

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   SYLVSGI 9
           SYLV+GI
Sbjct: 512 SYLVTGI 518
>NP_619639
          Length = 4074

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    QQSYLVSG 8
            Q +YLVSG
Sbjct: 2698 QLTYLVSG 2705
>NP_733842
          Length = 3396

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    QQSYLVSG 8
            Q +YLVSG
Sbjct: 2698 QLTYLVSG 2705
>NP_660187
          Length = 1344

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QQSYLVSG 8
           QQ+++VSG
Sbjct: 579 QQAWIVSG 586
>NP_149163
          Length = 1382

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QQSYLVSG 8
           QQ+++VSG
Sbjct: 579 QQAWIVSG 586
>NP_115972
          Length = 1382

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QQSYLVSG 8
           QQ+++VSG
Sbjct: 579 QQAWIVSG 586
>NP_001186434
          Length = 556

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  YLVSGI 9
          YLVSGI
Sbjct: 49 YLVSGI 54
>NP_899067
          Length = 518

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  YLVSGI 9
          YLVSGI
Sbjct: 11 YLVSGI 16
>NP_001268436
          Length = 518

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  YLVSGI 9
          YLVSGI
Sbjct: 11 YLVSGI 16
>NP_542403
          Length = 559

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  YLVSGI 9
          YLVSGI
Sbjct: 52 YLVSGI 57
>NP_899069
          Length = 448

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  YLVSGI 9
          YLVSGI
Sbjct: 11 YLVSGI 16
>NP_001186435
          Length = 518

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  YLVSGI 9
          YLVSGI
Sbjct: 11 YLVSGI 16
>NP_005994
          Length = 274

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SYLVSGI 9
           SYLV+G+
Sbjct: 114 SYLVTGV 120
>NP_001159392
          Length = 491

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QQSYLVSGI 9
           +QS +VSG+
Sbjct: 370 EQSLVVSGV 378
>NP_000925
          Length = 491

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QQSYLVSGI 9
           +QS +VSG+
Sbjct: 370 EQSLVVSGV 378
>NP_001159393
          Length = 427

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QQSYLVSGI 9
           +QS +VSG+
Sbjct: 306 EQSLVVSGV 314
>NP_001231933
          Length = 439

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   QQSYLVSGI 9
           Q+S++ SG+
Sbjct: 217 QESFVTSGV 225
>NP_005588
          Length = 428

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   QQSYLVSGI 9
           Q+S++ SG+
Sbjct: 217 QESFVTSGV 225
>NP_001026885
          Length = 1027

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   QSYLVSGI 9
           ++Y+VSG+
Sbjct: 572 EAYIVSGL 579
>NP_001231931
          Length = 508

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   QQSYLVSGI 9
           Q+S++ SG+
Sbjct: 217 QESFVTSGV 225
>NP_848639
          Length = 836

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   QQSYLV 6
           QQSYL+
Sbjct: 228 QQSYLI 233
>NP_056100
          Length = 1490

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   QSYLVSG 8
           Q YL+SG
Sbjct: 482 QRYLISG 488
>NP_443066
          Length = 1457

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   QSYLVSG 8
           Q YL+SG
Sbjct: 482 QRYLISG 488
>NP_997289
          Length = 534

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   QSYLVSG 8
           Q+YL+SG
Sbjct: 254 QNYLLSG 260
>NP_001166094
          Length = 1408

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SYLVSGI 9
           SYLV+G+
Sbjct: 914 SYLVTGL 920
>NP_995315
          Length = 499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   QQSYLVSGI 9
           Q+S++ SG+
Sbjct: 208 QESFVTSGV 216
>NP_002490
          Length = 1461

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SYLVSGI 9
           SYLV+G+
Sbjct: 914 SYLVTGL 920
>NP_001231934
          Length = 430

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   QQSYLVSGI 9
           Q+S++ SG+
Sbjct: 208 QESFVTSGV 216
>XP_006725318
          Length = 555

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QQSYLVSGI 9
           +QS +VSG+
Sbjct: 434 EQSLVVSGV 442
>XP_005258911
          Length = 798

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   QQSYLV 6
           QQSYL+
Sbjct: 190 QQSYLI 195
>XP_005258910
          Length = 810

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   QQSYLV 6
           QQSYL+
Sbjct: 202 QQSYLI 207
>XP_005259621
          Length = 511

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   QQSYLVSGI 9
           Q+S++ SG+
Sbjct: 217 QESFVTSGV 225
>XP_006722822
          Length = 526

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   QQSYLVSGI 9
           Q+S++ SG+
Sbjct: 208 QESFVTSGV 216
>XP_005259620
          Length = 535

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   QQSYLVSGI 9
           Q+S++ SG+
Sbjct: 217 QESFVTSGV 225
>XP_006722494
          Length = 1490

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   QSYLVSG 8
           Q YL+SG
Sbjct: 482 QRYLISG 488
>XP_005256760
          Length = 464

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QQSYLVSGI 9
           +QS +VSG+
Sbjct: 343 EQSLVVSGV 351
>XP_005256758
          Length = 491

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QQSYLVSGI 9
           +QS +VSG+
Sbjct: 370 EQSLVVSGV 378
>XP_005256757
          Length = 495

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QQSYLVSGI 9
           +QS +VSG+
Sbjct: 374 EQSLVVSGV 382
>XP_005256756
          Length = 526

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QQSYLVSGI 9
           +QS +VSG+
Sbjct: 405 EQSLVVSGV 413
>XP_005256755
          Length = 555

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   QQSYLVSGI 9
           +QS +VSG+
Sbjct: 434 EQSLVVSGV 442
>XP_005254473
          Length = 1408

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SYLVSGI 9
           SYLV+G+
Sbjct: 914 SYLVTGL 920
>XP_005254472
          Length = 1428

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SYLVSGI 9
           SYLV+G+
Sbjct: 934 SYLVTGL 940
>XP_005254471
          Length = 1450

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SYLVSGI 9
           SYLV+G+
Sbjct: 914 SYLVTGL 920
>XP_005254470
          Length = 1454

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SYLVSGI 9
           SYLV+G+
Sbjct: 918 SYLVTGL 924
>XP_005254469
          Length = 1461

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SYLVSGI 9
           SYLV+G+
Sbjct: 914 SYLVTGL 920
>XP_005254468
          Length = 1465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SYLVSGI 9
           SYLV+G+
Sbjct: 918 SYLVTGL 924
>XP_005254467
          Length = 1470

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SYLVSGI 9
           SYLV+G+
Sbjct: 934 SYLVTGL 940
>XP_005254465
          Length = 1481

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SYLVSGI 9
           SYLV+G+
Sbjct: 934 SYLVTGL 940
>XP_005250956
          Length = 371

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  QQSYLVSG 8
          ++S+LVSG
Sbjct: 4  EKSFLVSG 11
>NP_001166095
          Length = 1450

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SYLVSGI 9
           SYLV+G+
Sbjct: 914 SYLVTGL 920
>NP_001153019
          Length = 441

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   QSYLVSG 8
           Q+YL+SG
Sbjct: 254 QNYLLSG 260
>NP_000828
          Length = 371

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  QQSYLVSG 8
          ++S+LVSG
Sbjct: 4  EKSFLVSG 11
>NP_001009184
          Length = 371

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  QQSYLVSG 8
          ++S+LVSG
Sbjct: 4  EKSFLVSG 11
>NP_996776
          Length = 267

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   SYLVSGI 9
           S+L+SGI
Sbjct: 101 SFLISGI 107
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.314    0.130    0.333 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 494,612
Number of extensions: 879
Number of successful extensions: 74
Number of sequences better than 10000.0: 74
Number of HSP's gapped: 74
Number of HSP's successfully gapped: 74
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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