Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001177957                                                           18    1482
NP_036602                                                              18    1482
XP_006715974                                                           18    1482
NP_055752                                                              17    4312
XP_006717783                                                           17    4312
XP_006717782                                                           17    4312
NP_009057                                                              16    5631
NP_057336                                                              16    7355
NP_060656                                                              16    7355
XP_006712120                                                           16    7355
XP_005264512                                                           16    7355
XP_005264511                                                           16    7355
XP_006712119                                                           16    7355
XP_005264510                                                           16    7355
XP_006712118                                                           16    7355
XP_005264509                                                           16    7355
XP_005264508                                                           16    7355
XP_006712117                                                           16    7355
XP_005264507                                                           16    7355
XP_005264506                                                           16    7355
XP_005245376                                                           16    7355
XP_005245374                                                           16    7355
NP_001026895                                                           15    9605
NP_076996                                                              15    9605
NP_004740                                                              15    9605
NP_112162                                                              15    9605
NP_954573                                                              15    9605
NP_001230706                                                           15    9605
NP_001230705                                                           15    9605
NP_001248763                                                           15    9605
NP_055494                                                              15    9605
NP_862820                                                              15    9605
NP_001184188                                                           15    9605
NP_036513                                                              15    9605
XP_006719009                                                           15    9605
XP_006719008                                                           15    9605
XP_005248763                                                           15    9605
XP_005248762                                                           15    9605
XP_005248761                                                           15    9605
XP_006714561                                                           15    9605
XP_006711625                                                           15    9605
XP_005245577                                                           15    9605
XP_005245576                                                           15    9605
>NP_001177957
          Length = 859

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   QQLVSQLL 8
           QQLVSQLL
Sbjct: 767 QQLVSQLL 774
>NP_036602
          Length = 923

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   QQLVSQLL 8
           QQLVSQLL
Sbjct: 831 QQLVSQLL 838
>XP_006715974
          Length = 875

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   QQLVSQLL 8
           QQLVSQLL
Sbjct: 783 QQLVSQLL 790
>NP_055752
          Length = 1132

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   QQLVSQLL 8
           Q+L+SQLL
Sbjct: 596 QELISQLL 603
>XP_006717783
          Length = 641

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   QQLVSQLL 8
           Q+L+SQLL
Sbjct: 596 QELISQLL 603
>XP_006717782
          Length = 1089

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   QQLVSQLL 8
           Q+L+SQLL
Sbjct: 553 QELISQLL 560
>NP_009057
          Length = 806

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   QQLVSQLLT 9
           +++VSQLLT
Sbjct: 322 RRIVSQLLT 330
>NP_057336
          Length = 4857

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    QQLVSQLLT 9
            QQ++SQ+L+
Sbjct: 2988 QQIMSQILS 2996
>NP_060656
          Length = 853

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LVSQLLT 9
           L+SQLLT
Sbjct: 313 LISQLLT 319
>XP_006712120
          Length = 4812

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    QQLVSQLLT 9
            QQ++SQ+L+
Sbjct: 2943 QQIMSQILS 2951
>XP_005264512
          Length = 4840

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    QQLVSQLLT 9
            QQ++SQ+L+
Sbjct: 2971 QQIMSQILS 2979
>XP_005264511
          Length = 4847

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    QQLVSQLLT 9
            QQ++SQ+L+
Sbjct: 3015 QQIMSQILS 3023
>XP_006712119
          Length = 4851

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    QQLVSQLLT 9
            QQ++SQ+L+
Sbjct: 2982 QQIMSQILS 2990
>XP_005264510
          Length = 4861

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    QQLVSQLLT 9
            QQ++SQ+L+
Sbjct: 2992 QQIMSQILS 3000
>XP_006712118
          Length = 4864

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    QQLVSQLLT 9
            QQ++SQ+L+
Sbjct: 3015 QQIMSQILS 3023
>XP_005264509
          Length = 4870

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    QQLVSQLLT 9
            QQ++SQ+L+
Sbjct: 3001 QQIMSQILS 3009
>XP_005264508
          Length = 4875

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    QQLVSQLLT 9
            QQ++SQ+L+
Sbjct: 3006 QQIMSQILS 3014
>XP_006712117
          Length = 4878

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    QQLVSQLLT 9
            QQ++SQ+L+
Sbjct: 3009 QQIMSQILS 3017
>XP_005264507
          Length = 4880

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    QQLVSQLLT 9
            QQ++SQ+L+
Sbjct: 3011 QQIMSQILS 3019
>XP_005264506
          Length = 4884

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    QQLVSQLLT 9
            QQ++SQ+L+
Sbjct: 3015 QQIMSQILS 3023
>XP_005245376
          Length = 718

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LVSQLLT 9
           L+SQLLT
Sbjct: 178 LISQLLT 184
>XP_005245374
          Length = 911

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LVSQLLT 9
           L+SQLLT
Sbjct: 371 LISQLLT 377
>NP_001026895
          Length = 619

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQLVSQLL 8
           +QL SQLL
Sbjct: 392 EQLASQLL 399
>NP_076996
          Length = 662

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QLVSQLLT 9
           +L+SQ+LT
Sbjct: 294 KLISQMLT 301
>NP_004740
          Length = 631

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   QQLVSQLLT 9
           Q+L+++LLT
Sbjct: 201 QELLAELLT 209
>NP_112162
          Length = 521

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   QQLVSQLLT 9
           Q+L+++LLT
Sbjct: 201 QELLAELLT 209
>NP_954573
          Length = 521

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   QQLVSQLLT 9
           Q+L+++LLT
Sbjct: 201 QELLAELLT 209
>NP_001230706
          Length = 474

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQLVSQLL 8
           Q+L SQLL
Sbjct: 127 QELTSQLL 134
>NP_001230705
          Length = 491

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQLVSQLL 8
           Q+L SQLL
Sbjct: 118 QELTSQLL 125
>NP_001248763
          Length = 642

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   QQLVSQLLT 9
           Q+L+++LLT
Sbjct: 212 QELLAELLT 220
>NP_055494
          Length = 500

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQLVSQLL 8
           Q+L SQLL
Sbjct: 127 QELTSQLL 134
>NP_862820
          Length = 712

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QQLVSQLL 8
           Q+L+SQL+
Sbjct: 149 QKLISQLM 156
>NP_001184188
          Length = 568

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  QQLVSQLL 8
          Q+L+SQL+
Sbjct: 6  QKLISQLM 13
>NP_036513
          Length = 711

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QQLVSQLL 8
           Q+L+SQL+
Sbjct: 149 QKLISQLM 156
>XP_006719009
          Length = 438

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQLVSQLL 8
           Q+L SQLL
Sbjct: 127 QELTSQLL 134
>XP_006719008
          Length = 461

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQLVSQLL 8
           Q+L SQLL
Sbjct: 127 QELTSQLL 134
>XP_005248763
          Length = 659

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QQLVSQLL 8
           Q+L+SQL+
Sbjct: 96  QKLISQLM 103
>XP_005248762
          Length = 659

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QQLVSQLL 8
           Q+L+SQL+
Sbjct: 96  QKLISQLM 103
>XP_005248761
          Length = 684

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   QQLVSQLL 8
           Q+L+SQL+
Sbjct: 149 QKLISQLM 156
>XP_006714561
          Length = 662

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QLVSQLLT 9
           +L+SQ+LT
Sbjct: 294 KLISQMLT 301
>XP_006711625
          Length = 557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQLVSQLL 8
           +QL SQLL
Sbjct: 392 EQLASQLL 399
>XP_005245577
          Length = 567

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQLVSQLL 8
           +QL SQLL
Sbjct: 392 EQLASQLL 399
>XP_005245576
          Length = 576

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   QQLVSQLL 8
           +QL SQLL
Sbjct: 392 EQLASQLL 399
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.317    0.125    0.282 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 297,665
Number of extensions: 504
Number of successful extensions: 43
Number of sequences better than 10000.0: 43
Number of HSP's gapped: 43
Number of HSP's successfully gapped: 43
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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